Method for improvement of tolerance for therapeutically effective agents delivered by inhalation
    32.
    发明申请
    Method for improvement of tolerance for therapeutically effective agents delivered by inhalation 有权
    通过吸入改善治疗有效药物耐受性的方法

    公开(公告)号:US20060062738A1

    公开(公告)日:2006-03-23

    申请号:US11045234

    申请日:2005-01-28

    CPC classification number: A61K9/0075 A61K9/0078 A61K9/008

    Abstract: A method for improvement of tolerance for therapeutically effective agents delivered by inhalation comprising a pretreatment of a patient with a nebulized lidocaine or a lidocaine-like compound administered immediately or up to about thirty minutes before administration of the primary therapeutically effective agent. The pretreatment of the patient with the nebulized lidocaine or a lidocaine-like compound improves airway tolerance and deposition of the agent in the lungs and makes such deposition more safe, efficacious, controllable and predictable. The method of the invention is especially useful for enhancement of deposition of immunosuppressive agents in the lung(s) of transplant patients, improved tolerance of the drugs by reducing cough, and improving pulmonary drug deposition.

    Abstract translation: 一种用于改善通过吸入递送的治疗有效药物的耐受性的方法,其包括在给予主要治疗有效药剂之前立即施用或至多约30分钟施用雾化的利多卡因或利多卡因样化合物的患者的预处理。 患有雾化利多卡因或利多卡因样化合物的患者的预处理改善了气道耐受性并且将药物沉积在肺中,并使得沉积更安全,有效,可控和可预测。 本发明的方法对于增强免疫抑制剂在移植患者的肺中的沉积特别有用,通过减少咳嗽改善药物的耐受性并改善肺部药物沉积。

    PANEL MOUNTING BRACKET WITH GROUNDING MID-CLAMP AND RELATED METHODS

    公开(公告)号:US20180102731A1

    公开(公告)日:2018-04-12

    申请号:US15729125

    申请日:2017-10-10

    Inventor: Kevin Stapleton

    Abstract: A system for mounting a plurality of solar panels on a building may include mounting brackets each including a base to be positioned on the building and a vertical extension coupled to the base. A plurality of interior mounting clamps may each include a leg to be coupled to the vertical extension of a given panel mounting bracket. Each interior mounting clamp may also include a first lateral arm coupled to a distal end of the leg on a first side thereof for securing a first panel to the given panel mounting bracket with the first lateral arm having a first thickness, and a second lateral arm coupled to the distal end of the leg on a second side thereof opposite the first side for securing a second panel to the given panel mounting bracket with the second lateral arm having a second thickness less than the first thickness.

    Panel mounting bracket with under-mounting clamp and related methods

    公开(公告)号:US09628018B2

    公开(公告)日:2017-04-18

    申请号:US15203043

    申请日:2016-07-06

    Inventor: Kevin Stapleton

    Abstract: A system for mounting a solar panel(s) on a building, where the solar panel has an outer frame defining a lip. The system may include a plurality of panel mounting brackets each including a base to be positioned on the building, and a vertical extension having a proximal end coupled to the base and a distal end vertically spaced apart from the base, with the distal end defining a fastener channel therein. The system may also include a plurality of mounting clamps each including a bottom flange, and a top flange spaced apart from the bottom flange and partially overhanging the bottom flange and defining a slot therebetween to receive the lip. An end extension may couple respective ends of the bottom flange and top flange together, and a fastener channel connector may be coupled to the bottom flange and configured to be slidably received within the fastener channel.

    PANEL MOUNTING BRACKET ASSEMBLY INCLUDING AN ADJUSTABLE HEIGHT EXTENSION DEVICE AND RELATED METHODS
    35.
    发明申请
    PANEL MOUNTING BRACKET ASSEMBLY INCLUDING AN ADJUSTABLE HEIGHT EXTENSION DEVICE AND RELATED METHODS 审中-公开
    面板安装支架组件,包括可调高度延伸装置及相关方法

    公开(公告)号:US20170019058A1

    公开(公告)日:2017-01-19

    申请号:US15278544

    申请日:2016-09-28

    Inventor: Kevin Stapleton

    Abstract: A system for mounting a solar panel(s) may include a panel mounting bracket(s) having a base to be positioned on a building and a vertical extension including spaced apart vertical sidewalls extending vertically upward from the base and defining a cavity therebetween with a cross-support member extending laterally between the vertical sidewalls across the cavity. An adjustable height extension device is also provided which may include a lower portion carried within the cavity of the vertical extension and vertically slidable within the cavity, an upper portion carried by the lower portion to be connected with the solar panel(s), and a vertical height adjustment member including a head carried by the upper portion and a shaft threadably received by the cross support member to cause the lower portion to slide vertically within the cavity to adjust a vertical height of the upper portion as the vertical height adjustment member is rotated.

    Abstract translation: 一种用于安装太阳能电池板的系统可以包括具有要被定位在建筑物上的基座的面板安装支架和垂直延伸部分,该垂直延伸部分包括从底部向上垂直向上延伸的间隔开的垂直侧壁,并在其间限定一个空腔 交叉支撑构件横向延伸穿过空腔。 还提供了可调节的高度延伸装置,其可以包括承载在垂直延伸部的空腔内的下部,并且可以在空腔内垂直滑动,由下部承载以与太阳能电池板连接的上部, 垂直高度调节构件包括由上部承载的头部和由十字支撑构件螺纹地容纳的轴,以使得下部在空腔内垂直滑动,以在垂直高度调节构件旋转时调节上部的垂直高度 。

    Panel mounting bracket for standing seam roof and related methods
    36.
    发明授权
    Panel mounting bracket for standing seam roof and related methods 有权
    用于立式屋顶的面板安装支架及相关方法

    公开(公告)号:US09145685B2

    公开(公告)日:2015-09-29

    申请号:US14056209

    申请日:2013-10-17

    Inventor: Kevin Stapleton

    Abstract: A system is provided for mounting at least one solar panel on a roof having standing seams protruding outwardly therefrom. The system may include a plurality of panel mounting brackets each comprising first and second flanges laterally spaced apart to define a seam channel therebetween, with the seam channel for receiving a given standing seam therein when the first and second flanges are positioned on the roof straddling the given standing seam. Each panel mounting bracket may also include a vertical extension portion carried by the first and second flanges. The system may further include a plurality of clamps each configured to couple the vertical extension portion of a respective panel mounting bracket with the at least one solar panel.

    Abstract translation: 提供一种用于将至少一个太阳能电池板安装在具有从其向外突出的立起接缝的屋顶上的系统。 系统可以包括多个面板安装支架,每个面板安装支架包括横向间隔开的第一和第二凸缘以在其间限定接缝通道,其中当第一和第二凸缘位于横跨 给定立缝。 每个面板安装支架还可包括由第一和第二凸缘承载的垂直延伸部分。 系统还可以包括多个夹具,每个夹具被配置为将相应的面板安装支架的垂直延伸部分与至少一个太阳能面板联接。

    Method for improvement of tolerance for therapeutically effective agents delivered by inhalation
    37.
    发明授权
    Method for improvement of tolerance for therapeutically effective agents delivered by inhalation 有权
    通过吸入改善治疗有效药物耐受性的方法

    公开(公告)号:US07452524B2

    公开(公告)日:2008-11-18

    申请号:US11045234

    申请日:2005-01-28

    CPC classification number: A61K9/0075 A61K9/0078 A61K9/008

    Abstract: A method for improvement of tolerance for therapeutically effective agents delivered by inhalation comprising a pretreatment of a patient with a nebulized lidocaine or a lidocaine-like compound administered immediately or up to about thirty minutes before administration of the primary therapeutically effective agent. The pretreatment of the patient with the nebulized lidocaine or a lidocaine-like compound improves airway tolerance and deposition of the agent in the lungs and makes such deposition more safe, efficacious, controllable and predictable. The method of the invention is especially useful for enhancement of deposition of immunosuppressive agents in the lung(s) of transplant patients, improved tolerance of the drugs by reducing cough, and improving pulmonary drug deposition.

    Abstract translation: 一种用于改善通过吸入递送的治疗有效药物的耐受性的方法,其包括在给予主要治疗有效药剂之前立即施用或至多约30分钟施用雾化的利多卡因或利多卡因样化合物的患者的预处理。 患有雾化利多卡因或利多卡因样化合物的患者的预处理改善了气道耐受性并且将药物沉积在肺中,并使得沉积更安全,有效,可控和可预测。 本发明的方法对于增强免疫抑制剂在移植患者的肺中的沉积特别有用,通过减少咳嗽改善药物的耐受性并改善肺部药物沉积。

    Targeted delivery of lidocaine and other local anesthetics and a method for treatment of cough and tussive attacks
    38.
    发明授权
    Targeted delivery of lidocaine and other local anesthetics and a method for treatment of cough and tussive attacks 失效
    目标输送利多卡因和其他局部麻醉剂,以及治疗咳嗽和咳嗽发作的方法

    公开(公告)号:US07452523B2

    公开(公告)日:2008-11-18

    申请号:US11045226

    申请日:2005-01-28

    CPC classification number: A61K9/0075 A61K9/0078 A61K9/008

    Abstract: An anti-tussive nebulized solution for targeted delivery of lidocaine into conducting and central airways. A method for treatment of cough and tussive attacks or episodes using said lidocaine solution. A nebulized lidocaine solution administered in daily dose from about 10 mg to 80 mg of lidocaine dissolved in a saline and nebulized into an aerosol having a mass median aerodynamic diameter 3 μm to 10 μm and a geometric standard deviation less than 1.7 using an electronic nebulizer.

    Abstract translation: 一种用于将利多卡因有针对性地输送到导管和中央气道中的抗咳嗽雾化溶液。 使用利多卡因溶液治疗咳嗽和咳嗽发作或发作的方法。 雾化的利多卡因溶液以约10mg至80mg的溶解在盐水中的利多卡因和使用电子雾化器雾化成质量中值空气动力学直径3mum至10um,几何标准偏差的气溶胶施用。

    Inhalation device and method
    40.
    发明授权

    公开(公告)号:US07032593B2

    公开(公告)日:2006-04-25

    申请号:US10123319

    申请日:2002-04-17

    CPC classification number: A61M15/0028 A61M11/002 A61M2202/064

    Abstract: Inhaler and associated method for facilitating inhalation of dry powder medicaments by a patient. The inhaler is light and compact, allowing for convenient storage and portability by a patient. Additionally, a minimal number of steps are required by the patient to use the device from start to finish. The inhaler is self-contained, being provided to the patient with medicament having been pre-stored in a powder chamber. Upon release from this chamber, an accurate dosage of the dry powder medicament is available for inhalation. The inhaler may simply be disposed of following use.

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