Abstract:
Inhalation device and associated method for facilitating inhalation by a patient of powder medicaments contained in a receptacle. The inhalation device has a chamber for receiving the receptacle. A ring is circumferentially coupled to an inner surface of the chamber to achieve a higher reproducible emitted dose of medicament from the receptacle. The inhalation device also includes an improved implement for puncturing the receptacle, requiring less force and experiencing fewer failures.
Abstract:
A method for improvement of tolerance for therapeutically effective agents delivered by inhalation comprising a pretreatment of a patient with a nebulized lidocaine or a lidocaine-like compound administered immediately or up to about thirty minutes before administration of the primary therapeutically effective agent. The pretreatment of the patient with the nebulized lidocaine or a lidocaine-like compound improves airway tolerance and deposition of the agent in the lungs and makes such deposition more safe, efficacious, controllable and predictable. The method of the invention is especially useful for enhancement of deposition of immunosuppressive agents in the lung(s) of transplant patients, improved tolerance of the drugs by reducing cough, and improving pulmonary drug deposition.
Abstract:
A system for mounting a plurality of solar panels on a building may include mounting brackets each including a base to be positioned on the building and a vertical extension coupled to the base. A plurality of interior mounting clamps may each include a leg to be coupled to the vertical extension of a given panel mounting bracket. Each interior mounting clamp may also include a first lateral arm coupled to a distal end of the leg on a first side thereof for securing a first panel to the given panel mounting bracket with the first lateral arm having a first thickness, and a second lateral arm coupled to the distal end of the leg on a second side thereof opposite the first side for securing a second panel to the given panel mounting bracket with the second lateral arm having a second thickness less than the first thickness.
Abstract:
A system for mounting a solar panel(s) on a building, where the solar panel has an outer frame defining a lip. The system may include a plurality of panel mounting brackets each including a base to be positioned on the building, and a vertical extension having a proximal end coupled to the base and a distal end vertically spaced apart from the base, with the distal end defining a fastener channel therein. The system may also include a plurality of mounting clamps each including a bottom flange, and a top flange spaced apart from the bottom flange and partially overhanging the bottom flange and defining a slot therebetween to receive the lip. An end extension may couple respective ends of the bottom flange and top flange together, and a fastener channel connector may be coupled to the bottom flange and configured to be slidably received within the fastener channel.
Abstract:
A system for mounting a solar panel(s) may include a panel mounting bracket(s) having a base to be positioned on a building and a vertical extension including spaced apart vertical sidewalls extending vertically upward from the base and defining a cavity therebetween with a cross-support member extending laterally between the vertical sidewalls across the cavity. An adjustable height extension device is also provided which may include a lower portion carried within the cavity of the vertical extension and vertically slidable within the cavity, an upper portion carried by the lower portion to be connected with the solar panel(s), and a vertical height adjustment member including a head carried by the upper portion and a shaft threadably received by the cross support member to cause the lower portion to slide vertically within the cavity to adjust a vertical height of the upper portion as the vertical height adjustment member is rotated.
Abstract:
A system is provided for mounting at least one solar panel on a roof having standing seams protruding outwardly therefrom. The system may include a plurality of panel mounting brackets each comprising first and second flanges laterally spaced apart to define a seam channel therebetween, with the seam channel for receiving a given standing seam therein when the first and second flanges are positioned on the roof straddling the given standing seam. Each panel mounting bracket may also include a vertical extension portion carried by the first and second flanges. The system may further include a plurality of clamps each configured to couple the vertical extension portion of a respective panel mounting bracket with the at least one solar panel.
Abstract:
A method for improvement of tolerance for therapeutically effective agents delivered by inhalation comprising a pretreatment of a patient with a nebulized lidocaine or a lidocaine-like compound administered immediately or up to about thirty minutes before administration of the primary therapeutically effective agent. The pretreatment of the patient with the nebulized lidocaine or a lidocaine-like compound improves airway tolerance and deposition of the agent in the lungs and makes such deposition more safe, efficacious, controllable and predictable. The method of the invention is especially useful for enhancement of deposition of immunosuppressive agents in the lung(s) of transplant patients, improved tolerance of the drugs by reducing cough, and improving pulmonary drug deposition.
Abstract:
An anti-tussive nebulized solution for targeted delivery of lidocaine into conducting and central airways. A method for treatment of cough and tussive attacks or episodes using said lidocaine solution. A nebulized lidocaine solution administered in daily dose from about 10 mg to 80 mg of lidocaine dissolved in a saline and nebulized into an aerosol having a mass median aerodynamic diameter 3 μm to 10 μm and a geometric standard deviation less than 1.7 using an electronic nebulizer.
Abstract:
Inhalation device and associated method for facilitating inhalation by a patient of powder medicaments contained in a receptacle. The inhalation device has a chamber for receiving the receptacle. A ring is circumferentially coupled to an inner surface of the chamber to achieve a higher reproducible emitted dose of medicament from the receptacle. The inhalation device also includes an improved implement for puncturing the receptacle, requiring less force and experiencing fewer failures.
Abstract:
Inhaler and associated method for facilitating inhalation of dry powder medicaments by a patient. The inhaler is light and compact, allowing for convenient storage and portability by a patient. Additionally, a minimal number of steps are required by the patient to use the device from start to finish. The inhaler is self-contained, being provided to the patient with medicament having been pre-stored in a powder chamber. Upon release from this chamber, an accurate dosage of the dry powder medicament is available for inhalation. The inhaler may simply be disposed of following use.