公开(公告)号：US08679810B2

公开(公告)日：2014-03-25

申请号：US11673601

申请日：2007-02-12

Applicant: Ning Man Cheng ,  Yun Chung Leung ,  Wai Hung Lo

Inventor： Ning Man Cheng ,  Yun Chung Leung ,  Wai Hung Lo

IPC: C12N9/96 ,  C12N9/14 ,  C12N9/78 ,  C12P21/06 ,  A61K38/46 ,  A61K38/00 ,  C07H21/04

CPC classification number: C12N9/78 ,  A61K38/00 ,  C12N9/14

Abstract: The present invention provides an isolated and substantially purified recombinant human arginase having sufficiently high enzymatic activity and stability to maintain Adequate Arginine Depletion in a patient. The present invention also provides a pharmaceutical composition comprising the modified invention enzyme and method for treatment of diseases using the pharmaceutical composition.

Abstract translation: 本发明提供了具有足够高的酶活性和稳定性的分离和基本纯化的重组人精氨酸酶，以维持患者中足够的精氨酸消耗。 本发明还提供了包含该修饰的发明酶的药物组合物和使用该药物组合物治疗疾病的方法。

公开(公告)号：US20130295073A1

公开(公告)日：2013-11-07

申请号：US13995503

申请日：2011-12-16

Applicant: Ning Man Cheng

Inventor： Ning Man Cheng

IPC: A61K47/48 ,  A61K31/704 ,  A61K38/50

CPC classification number: A61K47/48215 ,  A61K31/704 ,  A61K38/50 ,  A61K47/60 ,  A61K2300/00

Abstract: The present invention provides a method for treatment of leukemia comprising administration of arginase to a subject in need thereof. In one embodiment, the leukemia is lymphocytic or myeloid. In another embodiment, the leukemia is arsenic resistant. In a further embodiment, the arginase is pegylated recombinant human arginase. In another embodiment, the arginase can be administrated in combination with a second therapeutic agent such as Doxorubicin in the treatment of leukemia.

Abstract translation: 本发明提供了一种治疗白血病的方法，包括向有需要的受试者施用精氨酸酶。 在一个实施方案中，白血病是淋巴细胞或骨髓。 在另一个实施方案中，白血病是耐砷的。 在另一个实施方案中，精氨酸酶是聚乙二醇化的重组人精氨酸酶。 在另一个实施方案中，精氨酸酶可以与第二治疗剂如多柔比星组合施用于白血病的治疗。

公开(公告)号：US20130190195A1

公开(公告)日：2013-07-25

申请号：US13555898

申请日：2012-07-23

Applicant: Man Cheng

Inventor： Man Cheng

IPC: C12Q1/68

CPC classification number: C12Q1/6809 ,  C12Q2523/313 ,  C12Q2535/125 ,  C12Q2563/149 ,  C12Q2565/543

Abstract: Particles that generate electromagnetic spectra upon appropriate illumination and in which the spectra can be converted to codes that reflect differences in the spectra are functionalized with a plurality of identical primer pairs on which bridge amplification can be performed. Using these particles, nucleic acids in a biological sample are amplified and exposed to a label that sends a signal only when bound to double-stranded DNA. The code for each particle is correlated with the primer pairs, and the captured nucleic acids are thus detected and identified. The procedure is useful for multiplex DNA or RNA detection as well as counting of target DNA and RNA molecules in the sample.

Abstract translation: 在适当的照射下产生电磁光谱并且其中光谱可被转换成反映光谱差异的代码的粒子可以用多个相同的引物对进行功能化，在该引物对上可进行桥接扩增。 使用这些颗粒，生物样品中的核酸被扩增并暴露于仅当结合到双链DNA时才发送信号的标签。 每个粒子的代码与引物对相关，因此检测和鉴定所捕获的核酸。 该程序可用于多重DNA或RNA检测以及样品中靶DNA和RNA分子的计数。

公开(公告)号：US08451896B2

公开(公告)日：2013-05-28

申请号：US12581316

申请日：2009-10-19

Applicant: Chi Keung Fong ,  Wai Kuen Cham ,  Ka Man Cheng ,  Yu Liu

Inventor： Chi Keung Fong ,  Wai Kuen Cham ,  Ka Man Cheng ,  Yu Liu

IPC: H04N7/12 ,  H04N7/50

CPC classification number: H04N7/50 ,  H04N19/126 ,  H04N19/159 ,  H04N19/172 ,  H04N19/196 ,  H04N19/61

Abstract: The invention relates to adjusting the quantization parameter in digital video coding. A shift value (QP Shift) is used to adjust the quantization parameter. The shift value is determined in a determining step 101. The video nature is determined and compared with a threshold in a comparing step 102 to adjust the shift value adaptively according to the frame type in an adjusting step 103. The shift value shifts the quantization parameter in a shifting step 104.

Abstract translation: 本发明涉及在数字视频编码中调整量化参数。 移位值（QP Shift）用于调整量化参数。 在确定步骤10​​1中确定移位值。在比较步骤102中确定视频特性并将其与阈值进行比较，以在调整步骤103中根据帧类型自适应地调整移位值。移位值将量化参数 在移动步骤104中。

公开(公告)号：US08259819B2

公开(公告)日：2012-09-04

申请号：US12635383

申请日：2009-12-10

Applicant: Yu Liu ,  Yan Huo ,  Ka Man Cheng

Inventor： Yu Liu ,  Yan Huo ,  Ka Man Cheng

IPC: H04N11/02

CPC classification number: G06T5/20 ,  H04N19/117 ,  H04N19/147 ,  H04N19/196 ,  H04N19/463 ,  H04N19/82

Abstract: The present invention relates to method and apparatus for improving video quality. The present invention provides a unified loop filter including: a pixel determining unit which determines the type of a pixel based on boundary strength; a similarity transforming unit which transforms a nonlinear filter into a nonlinear similarity-ordered statistics filter; and an integrating unit which integrates the nonlinear similarity-ordered statistics filter with a linear image filtering portion. The unified loop filter is applicable to filter reconstructed frames when an encoder or a decoder is processing a video signal.

Abstract translation: 本发明涉及用于提高视频质量的方法和装置。 本发明提供一种统一的环路滤波器，包括：像素确定单元，其基于边界强度确定像素的类型; 相似度变换单元，其将非线性滤波器变换为非线性相似性排序统计滤波器; 以及将非线性相似性排序统计滤波器与线性图像滤波部分进行积分的积分单元。 统一环路滤波器适用于在编码器或解码器处理视频信号时对重构帧进行滤波。

公开(公告)号：US20110192855A1

公开(公告)日：2011-08-11

申请号：US12854178

申请日：2010-08-11

Applicant: Ashleigh Ka Ying Chu ,  Nga Man Cheng ,  Chung Man Shum

Inventor： Ashleigh Ka Ying Chu ,  Nga Man Cheng ,  Chung Man Shum

IPC: B65D1/40

CPC classification number: B65D85/72 ,  B65D1/0292 ,  Y10S215/90

Abstract: A carbonated beverage container includes a bottle having a flexible sidewall of generally circular cross section, a cap for closing a top opening of the bottle, pairs of coupling elements provided on diametrically opposite portions of the sidewall respectively and configured to be pushed towards each other and couple together, thereby partially collapsing the bottle and expelling a predetermined amount of air therefrom. A method of preserving the taste of carbonated beverage in a container is also disclosed.

Abstract translation: 碳酸饮料容器包括具有大致圆形横截面的柔性侧壁的瓶子，用于封闭瓶子顶部开口的盖子，分别设置在侧壁的径向相对部分上并被配置为被推向彼此的一对联接元件， 连在一起，从而部分地塌缩瓶子并从中排出预定量的空气。 还公开了一种在容器中保持碳酸饮料的味道的方法。

公开(公告)号：US20110000358A1

公开(公告)日：2011-01-06

申请号：US12919765

申请日：2009-02-26

Applicant: Ning-Man Cheng ,  Alexander Hsiao Wang Ling

Inventor： Ning-Man Cheng ,  Alexander Hsiao Wang Ling

IPC: G10D3/18

CPC classification number: G10D3/18

Abstract: A shoulder rest (50) comprises an attachment piece (60), an abutment piece (62), and a padding piece (64) and is adapted for supporting a stringed instrument (80) such as violin or viola during playing, wherein the attachment piece (60) is adapted to clip onto an end button (82) of the stringed instrument (80) such that the contact surface between the stringed instrument (80) and the shoulder rest (50) is juxtaposing a bottom block of the stringed instrument (80).

Abstract translation: 肩部支架（50）包括安装件（60），邻接件（62）和衬垫件（64），并且适于在玩耍期间支撑诸如小提琴或中提琴的弦乐器（80），其中附件 片（60）适于夹在弦乐器（80）的端部按钮（82）上，使得弦乐器（80）和肩部支架（50）之间的接触表面并列着弦乐器的底部块 （80）。

公开(公告)号：US20100329341A1

公开(公告)日：2010-12-30

申请号：US12493785

申请日：2009-06-29

Applicant: Yan Ho KAM ,  Wan Chi SIU ,  Yui Lam CHAN ,  Wai Lam HUI ,  Wai Hong WONG ,  Ka Man CHENG ,  Yan HUO

Inventor： Yan Ho KAM ,  Wan Chi SIU ,  Yui Lam CHAN ,  Wai Lam HUI ,  Wai Hong WONG ,  Ka Man CHENG ,  Yan HUO

IPC: H04N7/26

CPC classification number: H04N19/157 ,  H04N19/109 ,  H04N19/11 ,  H04N19/139 ,  H04N19/14 ,  H04N19/176 ,  H04N19/61

Abstract: Method and apparatus for providing a fast and accurate video coding process are disclosed. After checking the coding history of certain coded video frame units of a video, the order of the inter prediction and the intra prediction is adaptively exchanged for each coding video frame unit of an inter frame. Furthermore, the computations for coding modes in the latter part of the computation order are selectively skipped so as to speed up the coding process without degrading the video quality.

Abstract translation: 公开了提供快速准确的视频编码过程的方法和装置。 在检查视频的某些编码视频帧单元的编码历史之后，针对帧间的每个编码视频帧单元自适应地交换帧间预测和帧内预测的顺序。 此外，选择性地跳过计算顺序的后半部分中的编码模式的计算，以便加速编码处理而不降低视频质量。

公开(公告)号：US20090147087A1

公开(公告)日：2009-06-11

申请号：US12000109

申请日：2007-12-10

Applicant: Chien-Man Cheng ,  I-Ping Huang

Inventor： Chien-Man Cheng ,  I-Ping Huang

IPC: H04N5/225

CPC classification number: H04N1/00278 ,  H04N1/00347 ,  H04N1/0044 ,  H04N1/00458 ,  H04N2101/00 ,  H04N2201/0087 ,  H04N2201/0089 ,  H04N2201/216

Abstract: A digital photo frame printer includes a printer casing module, an image-capturing module, an image-processing module, an image-displaying module, and an image-printing module. The image-capturing module is disposed in the printer casing module for capturing images of external objects. The image-processing module is disposed in the printer casing module and electrically connected with the image-capturing module for processing the images that have been captured via the image-capturing module. The image-displaying module is disposed in the printer casing module and electrically connected with the image-processing module for displaying images that have been processed via the image-processing module. The image-printing module is disposed in the printer casing module and electrically connected with the image-processing module for printing images that have been processed via the image-processing module.

Abstract translation: 数码相框打印机包括打印机外壳模块，图像捕获模块，图像处理模块，图像显示模块和图像打印模块。 图像捕获模块设置在打印机外壳模块中，用于捕获外部对象的图像。 图像处理模块设置在打印机壳体模块中并与图像捕获模块电连接，用于处理通过图像捕获模块捕获的图像。 图像显示模块设置在打印机外壳模块中，并与图像处理模块电连接，用于显示经由图像处理模块处理过的图像。 图像打印模块设置在打印机外壳模块中并与图像处理模块电连接，用于打印经由图像处理模块处理的图像。

公开(公告)号：US20080299638A1

公开(公告)日：2008-12-04

申请号：US11680631

申请日：2007-03-01

Applicant: Ning Man CHENG

Inventor： Ning Man CHENG

IPC: C12N9/96 ,  C12N9/78

CPC classification number: A61K38/50

Abstract: The invention discloses methods for treating hepatitis with human arginase I modified by polyethylene glycol and uses of it in manufacturing of a medicament.

Abstract translation: 本发明公开了用聚乙二醇修饰的人类精氨酸酶I治疗肝炎的方法及其在制备药物中的用途。