公开(公告)号：US20070004759A1

公开(公告)日：2007-01-04

申请号：US10573988

申请日：2004-10-02

Applicant: Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

Inventor： Jordi Tormo i Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

IPC: A01N43/90 ,  A01N37/18

CPC classification number: A01N43/90 ,  A01N37/22 ,  A01N2300/00

Abstract: The invention relates to fungicidal mixtures for combating rice pathogens containing in the form of active agents 1) a triazolopyrimidine derivative of formula (I) and 2) fenhexamid of formula (II) at a synergistically effective quantity and to a method for combating rice pathogens by the compound of formula (1) and the compound of formula (1) mixtures and the use the compound of formula (I) with the compound of formula (II) for producing such mixtures and agents containing said mixtures.

Abstract translation: 本发明涉及用于防治含有活性剂形式的水稻病原体的杀真菌混合物1）式（I）的三氮代嘧啶衍生物和2）协同有效量的式（II）的十六酰胺和通过以下方式对抗水稻病原体的方法： 式（1）化合物和式（1）化合物的混合物，以及将式（I）化合物与式（II）化合物用于制备含有所述混合物的混合物和试剂。

公开(公告)号：US07153860B2

公开(公告)日：2006-12-26

申请号：US10471532

申请日：2002-03-13

Applicant: Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Hubert Sauter ,  Markus Gewehr ,  Bernd Müller ,  Jordi Tormo i Blasco ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

Inventor： Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Hubert Sauter ,  Markus Gewehr ,  Bernd Müller ,  Jordi Tormo i Blasco ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC: C07D239/42 ,  A01N43/54 ,  C07D239/47

CPC classification number: C07D239/42 ,  A01N43/54 ,  A01N43/56 ,  A01N43/60 ,  A01N43/647 ,  A01N43/653 ,  A01N43/713 ,  A01N43/90 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D403/04 ,  C07D473/06 ,  C07D487/04

Abstract: The invention relates to 5-phenylpyrimidine of formula (I) wherein the substituents have the following designations: R1 represents a five to ten-membered saturated, partially unsaturated or aromatic monocyclic or bicyclic heterocycle which contains between one and four heteroatoms from the group O, N or S, and which can be substituted as defined in the description; R2 represents hydrogen, halogen, cyano, alkyl, halogenalkyl or alkoxy; R3 and R4 represent hydrogen, alkyl, halogenalkyl, cycloalkyl, halogencycloalkyl, alkenyl, halogenalkenyl, cycloalkenyl, alkinyl, halogenalkinyl or cycloalkinyl; together with the nitrogen atom to which they are bonded, R3 and R4 can also form a five or six-membered ring which can be split by a heteroatom and can carry at least one substituent; R5 and R6 represent hydrogen, halogen, alkyl, halogenalkyl or alkoxy; R1 and R8 represent hydrogen, halogen, alkyl or halogenalkyl; and R9 represents hydrogen, halogen, alkyl, alkoxy, cycloalkoxy, halogenalkoxy or alkoxycarbonyl. The invention also relates to methods and intermediate products for producing said compounds and the use of the same for controlling pathogenic fungi

Abstract translation: 本发明涉及式（I）的5-苯基嘧啶，其中取代基具有以下指定：R 1表示5至10元饱和，部分不饱和或芳族单环或双环杂环，其含有一个 和来自O，N或S基团的四个杂原子，并且可以如说明书中定义的那样被取代; R 2表示氢，卤素，氰基，烷基，卤代烷基或烷氧基; R 3和R 4代表氢，烷基，卤代烷基，环烷基，卤代烷基，烯基，卤代烯基，环烯基，炔基，卤代炔基或环炔基; 与它们所键合的氮原子一起，R 3和R 4还可以形成五元或六元环，其可以被杂原子分解并且可以携带 至少一个取代基; R 5和R 6代表氢，卤素，烷基，卤代烷基或烷氧基; R 1和R 8代表氢，卤素，烷基或卤代烷基; R 9表示氢，卤素，烷基，烷氧基，环烷氧基，卤代烷氧基或烷氧基羰基。 本发明还涉及用于生产所述化合物的方法和中间产物及其用于控制​​致病真菌的用途

公开(公告)号：US07148227B2

公开(公告)日：2006-12-12

申请号：US10508409

申请日：2003-03-19

Applicant: Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl ,  Ulrich Schöfl

Inventor： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl ,  Ulrich Schöfl

IPC: A61K31/519 ,  C07D487/04 ,  C07C69/738

CPC classification number: C07D487/04 ,  A01N43/90 ,  C07C255/57

Abstract: The invention relates to triazolopyrimidines of formula (I), in which the substituents are defined as follows: L1 represents cyano, S(═O)nA1 or C(═O)A2, wherein A1 stands for hydrogen, hydroxy, alkyl, alkylamino or dialkylamino; A2 stands for C1–C8 alkoxy, C1–C6 haloalkoxy or one of the groups named in A1; and n stands for 0, 1 or 2; L2, L3 represent hydrogen or halogen; L4, L5 represent hydrogen, halogen or alkyl; X represents halogen, cyano, alkyl, haloalkyl, alkoxy or haloalkoxy; R1 represents alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, alkadienyl, haloalkenyl, cycloalkenyl, alkynyl, haloalkynyl or cycloalkynyl, phenyl, naphthyl, or a five to ten-membered saturated, partially unsaturated or aromatic heterocyclus containing between one and four heteroatoms from the group containing O, N or S; R2 represents hydrogen or R1; R1 and R2 can form, together with the nitrogen atom to which they are bonded, a five or six-membered ring, which can be interrupted and/or substituted by an atom from the group O, N and S; whereby R1 and/or R2 can be substituted in accordance with the description. The invention also relates to methods and intermediate products for producing said compounds, to agents containing the latter and to the use of said compounds for combating harmful fungi.

Abstract translation: 本发明涉及式（I）的三唑并嘧啶，其中取代基定义如下：L 1表示氰基，S（-O）n A 1 或其中A 1代表氢，羟基，烷基，烷基氨基或二烷基氨基;或C（= O） A 2代表C 1 -C 8烷氧基，C 1 -C 6烷基，C 1 -C 6 - >卤代烷氧基或在A 中命名的基团之一; 而n代表0,1或2; L 2，L 3表示氢或卤素; L 4，L 5代表氢，卤素或烷基; X表示卤素，氰基，烷基，卤代烷基，烷氧基或卤代烷氧基; R 1表示烷基，卤代烷基，环烷基，卤代环烷基，烯基，链烯基，卤代烯基，环烯基，炔基，卤代炔基或环炔基，苯基，萘基或五至十元饱和，部分不饱和或芳族杂环 含有一个至四个来自含有O，N或S的基团的杂原子; R 2表示氢或R 1; R 1和R 2可以与它们所键合的氮原子一起形成五元或六元环，其可被中断和/或被 来自O，N和S族的原子; 其中R 1和/或R 2可以根据描述被取代。 本发明还涉及用于生产所述化合物的方法和中间产物，含有后者的试剂和所述化合物用于防治有害真菌的用途。

公开(公告)号：US20060264447A1

公开(公告)日：2006-11-23

申请号：US10574083

申请日：2004-10-07

Applicant: Jordi Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

Inventor： Jordi Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

IPC: A01N43/90 ,  A01N43/40

CPC classification number: A01N43/90 ,  A01N43/40 ,  A01N2300/00

Abstract: Fungicidal mixtures for controlling rice pathogens, which mixtures comprise, as active components, 1) the triazolopyrimidine derivative of the formula I, and 2) fluazinam of the formula II, in a synergistically effective amount, methods for controlling rice pathogens using mixtures of the compound I with the compound II, the use of the compound I with the compound II for preparing such mixtures and compositions comprising these mixtures are described.

Abstract translation: 用于控制水稻病原体的杀真菌混合物，其混合物包含作为活性组分的1）式I的三唑并嘧啶衍生物和2）协同有效量的式II的氟啶胺，使用化合物的混合物控制水稻病原体的方法 I与化合物II，描述了化合物I与化合物II用于制备这种混合物的用途和包含这些混合物的组合物。

公开(公告)号：US20060258685A1

公开(公告)日：2006-11-16

申请号：US10558251

申请日：2004-05-27

Applicant: Olivier Wagner ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Wassilios Grammenos ,  Andreas Gypser ,  Bernd Muller ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Jordi Blasco ,  Alan Akers ,  John-Bryan Speakman ,  Michael Rack ,  Reinhard Stierl ,  Maria Scherer ,  Ulrich Schofl ,  Siegfried Strathmann

Inventor： Olivier Wagner ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Wassilios Grammenos ,  Andreas Gypser ,  Bernd Muller ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Jordi Blasco ,  Alan Akers ,  John-Bryan Speakman ,  Michael Rack ,  Reinhard Stierl ,  Maria Scherer ,  Ulrich Schofl ,  Siegfried Strathmann

IPC: A61K31/519 ,  C07D487/04

CPC classification number: C07D487/04 ,  A01N43/90

Abstract: The invention relates to substituted pyrazolopyrimidines of formula (I) wherein the substituents have the following designations: L represents halogen, alkyl, halogenalkyl, alkenyl, alkoxy, amino, NHR, NR2, cyano, S(═O)nA1 or C(═O)A2, R representing alkyl or alkylcarbonyl, A1 representing hydrogen, hydroxy, alkyl, alkylamino or dialkylamino, n representing 0, 1 or 2, and A2 representing alkenyl, alkoxy, halogenalkoxy or one of the groups cited for A1; m represents 0 or 1 to 5; R1 represents alkyl, halogenalkyl, cycloalkyl, halogencycloalkyl, alkenyl, alkadienyl, halogenalkenyl, cycloalkenyl, alkinyl, halogenalkinyl or cycloalkinyl, phenyl, naphthyl, or a five-membered to ten-membered saturated, partially unsaturated or aromatic heterocycle containing between one and four heteroatoms from the group O, N or S; and R2 represents hydrogen or one of the groups cited for R1. Together with the nitrogen atom to which they are bonded, R1 and R2 can form a five-membered to six-membered ring that can be interrupted by an atom from the groups O, N and S, and R1 and/or R2 can also be substituted according to the description. Furthermore, in formula (I): X represents halogen, cyano, OH, alkyl, alkoxy or halogenalkoxy; Y represents a five-membered to ten-membered saturated, partially unsaturated or aromatic heterocycle according to the description, or a group X or another group according to the description; p represents 1 or 2, the groups Y being potentially different when p=2; and p represents 0, when X is according to the description. The invention also relates to methods and intermediate products for producing said compounds, agents containing the same, and the use thereof for controlling phytopathogenic fungi.

公开(公告)号：US20060172891A1

公开(公告)日：2006-08-03

申请号：US10548840

申请日：2004-03-20

Applicant: Markus Gewehr ,  Bernd Muller ,  Thomas Grote ,  Wassilios Grammenos ,  Andreas Gypser ,  Jordi Blasco ,  Anja Schwogler ,  Joachim Rheinheimer ,  Carsten Blettner ,  Frank Schieweck ,  Michael Rack ,  Ulrich Schofl ,  Siegfried Strathmann ,  Reinhard Stierl ,  Jan Rether

Inventor： Markus Gewehr ,  Bernd Muller ,  Thomas Grote ,  Wassilios Grammenos ,  Andreas Gypser ,  Jordi Blasco ,  Anja Schwogler ,  Joachim Rheinheimer ,  Carsten Blettner ,  Frank Schieweck ,  Michael Rack ,  Ulrich Schofl ,  Siegfried Strathmann ,  Reinhard Stierl ,  Jan Rether

IPC: C07D333/22 ,  A01N43/10

CPC classification number: C07D333/38

Abstract: The invention relates to novel biphenyl carboxamides of formula (I), wherein A, R, Z, X, Y, m and n have the meanings given in the description, to multiple methods for producing these substances, to their use for combating unwanted micro-organisms and to novel intermediate products and the production thereof.

公开(公告)号：US20060167017A1

公开(公告)日：2006-07-27

申请号：US10539039

申请日：2003-12-16

Applicant: Bernd Muller ,  Jordi Blasco ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Wassilios Grammenos ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

Inventor： Bernd Muller ,  Jordi Blasco ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Wassilios Grammenos ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

IPC: C07D487/04 ,  A01N43/90

CPC classification number: C07D487/04

Abstract: Triazolopyrimidines of the formula I where the index and the substituents are as defined below: R1 is C1-C10-alkyl, C2-C10-alkenyl, C2-C10-alkynyl, C3-C10-cycloalkyl, C3-C10-cycloalkenyl, phenyl, naphthyl, or a five- to ten-membered saturated, partially unsaturated or aromatic heterocycle which is attached via carbon to the triazolopyrimidine and contains one to four heteroatoms from the group consisting of N, O and S; R2 is C1-C4-alkyl which may be substituted by halogen, cyano, nitro or C1-C2-alkoxy; n is 0 or an integer from 1 to 4; R is as defined in the description; X is SOm—Rx, NRxRy or NRx—(C═O)—Ry; m is 0 or an integer from 1 to 3; and processes for preparing these compounds, compositions comprising them and their use for controlling harmful fungi are described.

Abstract translation: 其中指数和取代基如下定义的式I的三唑并嘧啶：R 1是C 1 -C 10 - 烷基， C 1 -C 10亚烷基，C 2 -C 10 - 炔基，C 3 - 亚烷基 C 1 -C 10 - 环烷基，C 3 -C 10 - 环烯基，苯基，萘基或五至十元饱和的， 部分不饱和或芳族杂环，其通过碳连接到三唑并嘧啶并且包含一至四个由N，O和S组成的组的杂原子; R 2是可以被卤素，氰基，硝基或C 1 H 3取代的C 1 -C 4 - 烷基 -C 2 - 烷氧基; n为0或1至4的整数; R如说明书所定义; X是SO x，x，x，x，y，x，y，x， - （CO）-R y; m为0或1〜3的整数; 并描述了制备这些化合物的方法，包含它们的组合物及其用于控制​​有害真菌的用途。

公开(公告)号：US20060154927A1

公开(公告)日：2006-07-13

申请号：US10561188

申请日：2004-06-19

Applicant: Jordi I Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhart Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

Inventor： Jordi I Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhart Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

IPC: A01N43/90

CPC classification number: A01N43/90 ,  A01N37/38 ,  A01N2300/00

Abstract: Fungicidal mixtures for controlling rice pathogens, comprising, as active components, 1) the triazolopyrimidine derivative of the formula I, and 2) an acryloylmorpholide of the formula II, in which X is chlorine or fluorine, in a synergistically effective amount, methods for controlling rice pathogens using mixtures of the compound I with the compounds II, the use of the compound I and the compounds II for preparing such mixtures and compositions comprising these mixtures are described.

Abstract translation: 用于控制水稻病原体的杀真菌混合物，其包含作为活性组分的1）式I的三唑并嘧啶衍生物，和2）式Ⅱ的丙烯酰吗啉，其中X为氯或氟，协同有效量，控制方法 描述了使用化合物I与化合物II的混合物的水稻病原体，化合物I和化合物II用于制备这种混合物的使用和包含这些混合物的组合物的用途。

公开(公告)号：US20060154924A1

公开(公告)日：2006-07-13

申请号：US11332221

申请日：2006-01-17

Applicant: Klaus Schelberger ,  Maria Scherer ,  Reinhold Saur ,  Karl Eicken ,  Egon Haden ,  Eberhard Ammermann ,  Thomas Grote ,  Gisela Lorenz ,  Siegfried Strathmann

Inventor： Klaus Schelberger ,  Maria Scherer ,  Reinhold Saur ,  Karl Eicken ,  Egon Haden ,  Eberhard Ammermann ,  Thomas Grote ,  Gisela Lorenz ,  Siegfried Strathmann

IPC: A01N43/56 ,  A01N43/12 ,  A01N43/58 ,  A01N43/54 ,  A01N43/40 ,  A01N43/78

CPC classification number: A01N43/40 ,  A01N43/84 ,  A01N43/56 ,  A01N43/10 ,  A01N37/52 ,  A01N2300/00

Abstract: Fungicidal mixtures, comprising as active components a) a morpholine or piperidine derivative I selected from the group of the compounds Ia, Ib, Ic and Id b) compounds of the formula II where the substituents X1 to X5 and R1 to R4 are as defined below: X1 is C1-C4-haloalkyl, C1-C4-haloalkoxy or halogen; X2 to X5 are, independently of one another, hydrogen, halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy or C1-C4-haloalkoxy; R1 is C1-C4-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C1-C4-alkyl-C3-C7-cycloalkyl, C1-C4-alkyl-C3-C7-cycloalkenyl, where these radicals may carry substituents selected from the group consisting of halogen, cyano and C1-C4-alkoxy, R2 is a phenyl radical or a 5- or 6-membered saturated or unsaturated heterocyclyl radical having at least one heteroatom selected from the group consisting of N, O and S, where the cyclic radicals may have one to three substituents selected from the group consisting of halogen, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-haloalkyl, C1-C4-haloalkoxy, C1-C4-alkoxy-C2-C4-alkenyl, C1-C4-alkoxy-C2-C4-alkynyl, R3 and R4 are, independently of one another, hydrogen, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-alkylthio, N-C1-C4-alkylamino, C1-C4-haloalkyl or C1-C4-haloalkoxy in a synergistically effective amount are described.

公开(公告)号：US20060128727A1

公开(公告)日：2006-06-15

申请号：US10559461

申请日：2004-06-08

Applicant: Jordi Tormo I Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

Inventor： Jordi Tormo I Blasco ,  Thomas Grote ,  Maria Scherer ,  Reinhard Stierl ,  Siegfried Strathmann ,  Ulrich Schofl

IPC: A01N43/54 ,  A01N43/90

CPC classification number: A01N43/90 ,  A01N43/54 ,  A01N2300/00

Abstract: Fungicidal mixtures, comprising, as active components: 1) the triazolopyrimidine derivative of the formula I, 2) a pyrimidineanilide of the formula II, in which R is methyl, cyclopropyl or 1-propynyl, in a synergistically effective amount, methods for controlling harmful fungi from the class of the Oomycetes using mixtures of the compound I with one of the compounds II, and the use of the compound I with one of the compounds II for preparing such mixtures and compositions comprising these mixtures are described.

Abstract translation: 包含作为活性成分的杀真菌混合物：1）式I的三唑并嘧啶衍生物，2）式Ⅱ的嘧啶酰苯胺，其中R是甲基，环丙基或1-丙炔基，协同有效量，用于控制有害的 描述了使用化合物I与化合物II之一的混合物从卵菌纲类中获得的真菌，以及化合物I与化合物II之一用于制备这些混合物和包含这些混合物的组合物的用途。