公开(公告)号：US08213015B2

公开(公告)日：2012-07-03

申请号：US12237398

申请日：2008-09-25

Applicant: Karsten Kraizcek ,  Beno Mueller ,  Timothy Beerling

Inventor： Karsten Kraizcek ,  Beno Mueller ,  Timothy Beerling

IPC: G01N21/00

CPC classification number: G01N30/74 ,  B81B2201/058 ,  B81B2203/0338 ,  B81B2203/0392 ,  B81C1/00071 ,  H01L31/101

Abstract: An integrated flow cell, the flow cell comprising a semiconductor substrate, and a fluidic conduit having an at least partially transparent semiconductor oxide tubing, wherein the semiconductor oxide tubing is formed with the semiconductor substrate.

Abstract translation: 集成流通池，所述流动池包括半导体衬底和具有至少部分透明的半导体氧化物管的流体导管，其中所述半导体氧化物管与所述半导体衬底形成。

公开(公告)号：US20090206293A1

公开(公告)日：2009-08-20

申请号：US12032419

申请日：2008-02-15

Applicant: Timothy Beerling ,  Harry F. Prest

Inventor： Timothy Beerling ,  Harry F. Prest

IPC: F16K7/12

CPC classification number: F16K99/0001 ,  F16K99/0026 ,  F16K99/0059 ,  G05D7/0694

Abstract: An apparatus and method for controlling the flow of fluid though a channel. A first substrate defines features comprising a first channel. At least a portion of the first channel is bounded a deformable material having a first contour in which the first channel has a first cross-sectional area and a second contour in which the first channel has a second cross-sectional area.

Abstract translation: 用于控制通过通道的流体流动的装置和方法。 第一衬底限定包括第一通道的特征。 第一通道的至少一部分被界定为具有第一轮廓的可变形材料，其中第一通道具有第一横截面积和第二轮廓，其中第一通道具有第二横截面积。

公开(公告)号：US20090087924A1

公开(公告)日：2009-04-02

申请号：US11864982

申请日：2007-09-29

Applicant: Magdalena Bynum ,  Timothy Beerling ,  Brian Peter ,  Marc Valer Serra ,  Hui Wang

Inventor： Magdalena Bynum ,  Timothy Beerling ,  Brian Peter ,  Marc Valer Serra ,  Hui Wang

IPC: G01N33/543 ,  B01J19/00 ,  G01N21/64

CPC classification number: G01N33/6803 ,  B01L3/5027 ,  B01L3/502753 ,  B01L9/527 ,  G01N21/33 ,  G01N21/553 ,  G01N33/54386 ,  G01N2021/6439 ,  G01N2458/00

Abstract: The microfluidic reverse affinity-blot device of the present disclosure combines affinity binding for isolation and/or enrichment of protein(s) from a sample, followed by separation/identification thereof. In general terms, a microfluidic reverse affinity-blot device is a closed system of interconnected components that is comprised of defined points of entry and exit, wherein the interconnected components include a capture region upstream from a protein separation region and subsequent detection region. Methods of use are also described.

Abstract translation: 本公开的微流体反向亲和力印迹装置结合亲和结合用于从样品中分离和/或富集蛋白质，然后分离/鉴定。 通常来说，微流体反向亲和印迹装置是由限定的入口和出口点组成的互连部件的封闭系统，其中相互连接的部件包括蛋白质分离区域和后续检测区域上游的捕获区域。 还描述了使用方法。

公开(公告)号：US07488908B2

公开(公告)日：2009-02-10

申请号：US11254906

申请日：2005-10-20

Applicant: Timothy Beerling

Inventor： Timothy Beerling

IPC: H01H29/00

CPC classification number: H01H29/06 ,  H01H29/28 ,  H01H2029/008

Abstract: A liquid metal switch uses a conductive liquid droplet of a material containing gallium as a substitute for mercury. A secondary fluid surrounding the material containing gallium prevents the formation of oxide on a surface of the conductive liquid droplet.

Abstract translation: 液体金属开关使用含有镓的材料的导电液滴作为汞的替代物。 围绕含有镓的材料的次级流体防止在导电液滴的表面上形成氧化物。

公开(公告)号：US20070218454A1

公开(公告)日：2007-09-20

申请号：US11378760

申请日：2006-03-16

Applicant: Reid Brennen ,  Timothy Beerling ,  Hongfeng Yin ,  Kevin Killeen

Inventor： Reid Brennen ,  Timothy Beerling ,  Hongfeng Yin ,  Kevin Killeen

IPC: C12Q1/00

CPC classification number: G01N21/0303 ,  G01N2021/036 ,  G01N2201/0245

Abstract: The present invention relates to an optical detection cell for micro-fluidics. The detection cell provides a first layer, a detection cell layer contacting the first layer, a third layer contacting the detection cell layer and a detection channel defined through the detection cell to serve as a light path for receiving light for detecting a molecule Methods of detecting molecules and making the detection cell are also disclosed

Abstract translation: 本发明涉及一种用于微流体学的光学检测单元。 检测单元提供第一层，接触第一层的检测单元层，接触检测单元层的第三层和通过检测单元定义的检测通道，用作接收用于检测分子的光的光路。检测方法 分子和制备检测电池也被公开

公开(公告)号：US20070125178A1

公开(公告)日：2007-06-07

申请号：US11297019

申请日：2005-12-07

Applicant: Steven Rosenau ,  Timothy Beerling ,  Michael Frank

Inventor： Steven Rosenau ,  Timothy Beerling ,  Michael Frank

IPC: G01L9/12

CPC classification number: G01L9/0095

Abstract: Capacitive sensors using liquid metals can be fabricated using MEMS device design and fabrication techniques. Movement of the liquid metal in response to a stimulus can provide measurable changes in capacitance of the devices.

Abstract translation: 使用液体金属的电容传感器可以使用MEMS器件设计和制造技术来制造。 液体金属响应于刺激的移动可以提供装置的电容的可测量的变化。

公开(公告)号：US07183509B2

公开(公告)日：2007-02-27

申请号：US11391583

申请日：2006-03-28

Applicant: Timothy Beerling

Inventor： Timothy Beerling

IPC: H01H57/00

CPC classification number: H01H29/00 ,  H01H59/0009 ,  H01H2029/008

Abstract: A switch comprises a first switch element configured to actuate by electrowetting, the first switch element comprising at least two radio frequency contacts and at least two control electrodes. The switch also comprises at least two additional switch elements configured to make and break an electrical connection between the at least two control electrodes of the first switch element.

Abstract translation: 开关包括被配置为通过电润湿致动的第一开关元件，所述第一开关元件包括至少两个射频触点和至少两个控制电极。 开关还包括至少两个额外的开关元件，其被配置为制造和断开第一开关元件的至少两个控制电极之间的电连接。

公开(公告)号：US20060249361A1

公开(公告)日：2006-11-09

申请号：US11391583

申请日：2006-03-28

Applicant: Timothy Beerling

Inventor： Timothy Beerling

IPC: H01H57/00

CPC classification number: H01H29/00 ,  H01H59/0009 ,  H01H2029/008

Abstract: A switch comprises a first switch element configured to actuate by electrowetting, the first switch element comprising at least two radio frequency contacts and at least two control electrodes. The switch also comprises at least two additional switch elements configured to make and break an electrical connection between the at least two control electrodes of the first switch element.

公开(公告)号：US20060201795A1

公开(公告)日：2006-09-14

申请号：US11416284

申请日：2006-05-02

Applicant: Timothy Beerling

Inventor： Timothy Beerling

IPC: H01H29/00

CPC classification number: H01H59/0009 ,  H01H29/00 ,  H01H2001/0042 ,  H01H2029/008

Abstract: An electronic switch comprises a substrate having a surface and an embedded electrode, a droplet of conductive liquid located over the embedded electrode, and a power source configured to create an electric circuit including the droplet of conductive liquid. The surface comprises a feature that determines a contact angle between the surface and the droplet.

公开(公告)号：US20060108209A1

公开(公告)日：2006-05-25

申请号：US10996823

申请日：2004-11-24

Applicant: Timothy Beerling

Inventor： Timothy Beerling

IPC: H01H29/00

CPC classification number: H01H59/0009 ,  H01H29/00 ,  H01H2001/0042 ,  H01H2029/008

Abstract: An electronic switch comprises a substrate having a surface and an embedded electrode, a droplet of conductive liquid located over the embedded electrode, and a power source configured to create an electric circuit including the droplet of conductive liquid. The surface comprises a feature that determines a contact angle between the surface and the droplet.