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    VALVES AND OTHER FLOW CONTROL IN FLUIDIC SYSTEMS INCLUDING MICROFLUIDIC SYSTEMS
    2.
    发明申请
    VALVES AND OTHER FLOW CONTROL IN FLUIDIC SYSTEMS INCLUDING MICROFLUIDIC SYSTEMS 审中-公开
    流体系统中的阀门和其他流量控制，包括微流体系统

    公开(公告)号：US20160250638A1

    公开(公告)日：2016-09-01

    申请号：US15148955

    申请日：2016-05-06

    申请人： President and Fellows of Harvard College

    发明人： Adam R. Abate ,  David A. Weitz

    IPC分类号： B01L3/00 ,  F16K99/00

    CPC分类号： B01L3/502738 ,  B01L3/0268 ,  B01L3/502746 ,  B01L3/502784 ,  B01L2200/0605 ,  B01L2200/0636 ,  B01L2200/146 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2400/0487 ,  B01L2400/0655 ,  B01L2400/082 ,  F16K99/0017 ,  F16K99/0026 ,  F16K99/0055 ,  Y10T436/2575

    摘要： Articles and methods for controlling flow in fluidic systems, especially in microfluidic systems, are provided. In one aspect, a microfluidic system described herein includes a configuration such that the actuation of a single valve can allow the switching of fluids from a first fluid path (e.g., a first channel section) to a second fluid path (e.g., a second channel section). This may be achieved, for example, by incorporating a valve with a first channel section, which may have a lower hydrodynamic resistance than a second channel section prior to actuation of the valve. Actuation of the valve can cause only the hydrodynamic resistance of the first channel section to increase, thereby redirecting fluid flow into the second channel section (which now has a relatively lower hydrodynamic resistance). In some embodiments, the valve comprises a control channel for introducing a positive or reduced pressure, and is adapted to modulate fluid flow in an adjacent channel section by constricting or expanding the channel section. For example, the valve and/or the channel section may be formed in a flexible material and actuation of the valve may be achieved by applying a positive or reduced pressure to the valve to cause deformation of both the valve and the channel section. Another aspect of the invention includes articles and methods associated with manipulation of multiphase materials (e.g., dispersions). For instance, one or more valves may be combined with a flow focusing system so as to form droplets of different volumes and/or frequencies without the need to vary flow rates of the fluids when they are introduced into the fluidic system.

    摘要翻译： 提供了用于控制流体系统流动的文章和方法，特别是在微流体系统中。 在一个方面，本文所述的微流体系统包括使得单个阀的致动可以允许流体从第一流体路径（例如，第一通道部分）切换到第二流体路径（例如，第二通道 部分）。 这可以通过例如通过结合具有第一通道部分的阀来实现，该阀在致动阀之前可具有比第二通道部分更低的流体动力阻力。 阀的致动只能使第一通道部分的流体动力阻力增加，从而将流体流转向第二通道部分（其现在具有相对较低的流体动力阻力）。 在一些实施例中，阀包括用于引入正压或减压的控制通道，并且适于通过收缩或扩大通道部分来调制相邻通道部分中的流体流动。 例如，阀和/或通道部分可以形成为柔性材料，并且可以通过向阀施加正压或减压以使阀和通道部分变形来实现阀的致动。 本发明的另一方面包括与多相材料（例如分散体）的操作有关的制品和方法。 例如，一个或多个阀可以与流动聚焦系统组合，以便形成不同体积和/或频率的液滴，而不需要在将流体引入流体系统时改变流体的流速。

    MICROFLUIDIC PRESSURE AMPLIFIER CIRCUITS AND ELECTROSTATIC GATES FOR PNEUMATIC MICROSYSTEMS
    3.
    发明申请
    MICROFLUIDIC PRESSURE AMPLIFIER CIRCUITS AND ELECTROSTATIC GATES FOR PNEUMATIC MICROSYSTEMS 有权
    微型压力放大器电路和静电屏蔽气囊

    公开(公告)号：US20130313452A1

    公开(公告)日：2013-11-28

    申请号：US13901200

    申请日：2013-05-23

    申请人： The Board of Trustees of the University of Illinois

    发明人： Joshua D. Tice ,  Thomas A. Bassett ,  Amit V. Desai ,  Christopher A. Apblett ,  Paul A. Kenis

    IPC分类号： F16K31/02

    CPC分类号： F16K31/02 ,  F16K99/0026 ,  F16K99/0051 ,  F16K2099/0084

    摘要： An electrostatic actuator is provide that can include a fluidic line, a first electrode, and a second electrode such that a gate chamber portion of the fluidic line is sandwiched between the first electrode and the second electrode. The electrostatic actuator can also include a pressure-balancing channel in fluid communication with the gate chamber portion where the first electrode is sandwiched between the pressure-balancing channel and the gate chamber portion. A pneumatic valve system is provided which includes an electrostatic gate and a fluidic channel fluidly separate from a fluidic control line. A pneumatic valve portion of the fluidic control line can be positioned relative to a portion of the fluidic channel such that expansion of the pneumatic valve portion restricts fluid flow through the fluidic channel. Methods of using an electrostatic actuator and a pneumatic valve system are also provided.

    摘要翻译： 提供静电致动器，其可以包括流体管线，第一电极和第二电极，使得流体管线的门室部分被夹在第一电极和第二电极之间。 静电致动器还可以包括与门室部分流体连通的压力平衡通道，其中第一电极夹在压力平衡通道和门室部分之间。 提供了一种气动阀系统，其包括静电门和与流体控制线流体分离的流体通道。 流体控制线的气动阀部分可以相对于流体通道的一部分定位，使得气动阀部分的膨胀限制流体流过流体通道的流体。 还提供了使用静电致动器和气动阀系统的方法。

    Flow resistor
    9.
    发明申请
    Flow resistor 审中-公开
    流量电阻器

    公开(公告)号：US20120273077A1

    公开(公告)日：2012-11-01

    申请号：US13404061

    申请日：2012-02-24

    申请人： Walter LANG ,  Kai BURDORF

    发明人： Walter LANG ,  Kai BURDORF

    IPC分类号： F16L55/027

    CPC分类号： F16K99/0001 ,  F16K99/0015 ,  F16K99/0026 ,  F16K99/0034 ,  F16K99/0036 ,  F16K99/0061 ,  F16K2099/0074 ,  F16K2099/0086

    摘要： A flow resistor having a flow conduit with an inlet opening and an outlet opening, and a membrane forming a wall of the flow conduit, and a cross section of the flow of the flow conduit can be varied by exerting pressure on the membrane. The flow resistor has a cavity containing a medium with a positive temperature coefficient and a flow chamber; the membrane separates the cavity from the flow chamber and is both the wall of the cavity as well as the wall of the flow conduit, wherein the flow conduit is constructed as a helical recess, open to the membrane, in a surface of a lower cover that closes the flow chamber, wherein an inflow opening is arranged in the center of an area fixed by the flow conduit and wherein an outflow opening is arranged on the edge side.

    摘要翻译： 具有具有入口开口和出口开口的流动导管和形成流动导管的壁的膜的流动阻力器以及流动管道的流动的横截面可以通过施加膜上的压力来改变。 流量电阻器具有包含具有正温度系数的介质和流动室的空腔; 所述膜将所述空腔与所述流动室分离，并且是所述空腔的壁以及所述流动管道的壁，其中所述流动导管构造为在所述下盖的表面中的开口的螺旋形凹部 关闭流动室，其中流入口布置在由流动管道固定的区域的中心，并且其中流出口布置在边缘侧。

    Valves with Hydraulic Actuation System
    10.
    发明申请
    Valves with Hydraulic Actuation System 审中-公开
    带液压驱动系统的阀门

    公开(公告)号：US20120181460A1

    公开(公告)日：2012-07-19

    申请号：US13349832

    申请日：2012-01-13

    申请人： David Eberhart ,  Ezra Van Gelder

    发明人： David Eberhart ,  Ezra Van Gelder

    IPC分类号： F16K31/00

    CPC分类号： F16K99/0015 ,  F16K99/0026 ,  F16K99/0059

    摘要： This invention provides a device comprising at least one diaphragm valve actuated by a hydraulic actuation system. The device comprises a fluidics layer, an actuation layer and an elastic layer sandwiched between the fluidics layer and the actuation layer. The diaphragm valve comprises: a valve inlet and valve outlet comprised in the fluidics layer; a valve seat; a diaphragm comprised in the elastic layer; and an actuator. The diaphragm is actuatable to move into contact or out of contact with the valve seat, thereby closing or opening the diaphragm valve. The actuator comprises: a hydraulic conduit; a translator; and an incompressible fluid contained within the hydraulic conduit, wherein the incompressible fluid communicates with the translator and with the diaphragm. Translation of the translator transmits pressure through the incompressible fluid to actuate the diaphragm. The invention also provides systems including elements to operate the device and methods of using the device.

    摘要翻译： 本发明提供了一种包括由液压致动系统致动的至少一个隔膜阀的装置。 该装置包括流体层，致动层和夹在流体层和致动层之间的弹性层。 隔膜阀包括：流体层中包括的阀入口和阀出口; 阀座; 包括在弹性层中的隔膜; 和致动器。 隔膜可致动以与阀座接触或脱离接触，从而关闭或打开隔膜阀。 致动器包括：液压管道; 翻译员 以及包含在液压管道内的不可压缩流体，其中不可压缩流体与平移器和隔膜连通。 翻译器的翻译通过不可压缩流体传递压力以致动隔膜。 本发明还提供了包括用于操作设备的元件和使用该设备的方法的系统。