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31.
公开(公告)号:US20240252697A1
公开(公告)日:2024-08-01
申请号:US18629098
申请日:2024-04-08
Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Se , The University of Strathclyde
Inventor: Chintamani Atreya , Michelle Maclean , John G. Anderson , Scott J. MacGregor
CPC classification number: A61L2/0052 , A61L2/084 , A61L2202/122 , A61L2202/22
Abstract: Disclosed herein are methods and devices for the inactivation of pathogens (e.g., bacteria, viruses, etc.) in ex vivo stored blood products, such as plasma and/or platelets, by means of directing visible light radiation from an illuminating device into blood product storage containers in order to achieve effective pathogen inactivation without the presence of an added photosensitising agent in the blood product. An exemplary apparatus includes a control unit that operates a light source that emits light in the wavelength region of about 380-500 nm which is directed onto blood product storage bags at sufficient intensity to penetrate the bag material and the opaque blood product therein in order to inactivate pathogens in the blood product but at dose levels that cause no significant detrimental effects on the blood product.
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公开(公告)号:US11964944B2
公开(公告)日:2024-04-23
申请号:US17831049
申请日:2022-06-02
Applicant: The University of Chicago , University of Leeds , The J. Craig Venter Institute , Institute For Systems Biology , U.S. Government, as represented by The Secretary of The Army Medical Command (MEDCOM) , The University of Strathclyde
Inventor: Rima McLeod , Martin McPhillie , Colin W. G. Fishwick , Hernan Alejandro Lorenzi , Kai Wang , Taek-Kyun Kim , Yong Zhou , Leroy E. Hood , Ying Zhou , Kamal El Bissati , Mark Hickman , QiGui Li , Craig Roberts
IPC: C07D215/233 , A61P33/06 , C07D401/12 , C07D405/12 , C07D471/04 , C07D487/04
CPC classification number: C07D215/233 , A61P33/06 , C07D401/12 , C07D405/12 , C07D471/04 , C07D487/04
Abstract: Disclosed herein are novel compounds for treating apicomplexan parasite related disorders, methods for their use; cell line and non-human animal models of the dormant parasite phenotype and methods for their use in identifying new drugs to treat apicomplexan parasite related disorders, and biomarkers to identify disease due to the parasite and its response to treatment.
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公开(公告)号:US11747302B2
公开(公告)日:2023-09-05
申请号:US17261336
申请日:2019-07-11
Applicant: NPL Management Limited , The University of Strathclyde
Inventor: Witold Chalupczak , Rafal Gartman , Patrick Bevington
IPC: G01N27/82
CPC classification number: G01N27/82
Abstract: Disclosed herein is a method of detecting a material response. The method includes providing an oscillating primary magnetic field to cause as ample to produce a secondary magnetic field. The method also includes reducing the effect on an atomic magnetometer of components of the primary and secondary magnetic fields in a direction substantially orthogonal to a surface of the sample. The method also includes detecting the secondary magnetic field with the atomic magnetometer to detect the material response.
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公开(公告)号:US20230252672A1
公开(公告)日:2023-08-10
申请号:US18014609
申请日:2021-07-06
Applicant: University of Strathclyde
Inventor: Michael Strain
CPC classification number: G06T7/73 , G06T7/33 , G03F9/7088 , G06T2207/30148 , G06T2207/30204
Abstract: A method for use in the spatial registration of first and second objects comprises fixing the first and second objects to the same motion control stage in an unknown spatial relationship, using an imaging system to acquire an image of the first object, determining a position and orientation of the first object in a frame of reference of the motion control stage based at least in part on the acquired image of the first object, using the imaging system to acquire an image of the second object, and determining a position and orientation of the second object in the frame of reference of the motion control stage based at least in part on the acquired image of the second object. The method may be used in the spatial registration of first and second objects and, in particular though not exclusively, for use in the spatial registration of optical or electronic components relative to one another, or for use in the alignment of a first object such as an optical or electronic component relative to a second object such as a feature, a structure, a target area or a target region defined on a substrate or a wafer.
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公开(公告)号:US11596304B2
公开(公告)日:2023-03-07
申请号:US16651449
申请日:2018-08-22
Applicant: University of Strathclyde
Inventor: Martin David Dawson , Keith Mathieson , Gabor Varkonyi , Jonathan McKendry
IPC: H04B10/114 , A61B5/00 , A61N1/372 , H04L7/00 , A61B5/24
Abstract: An interface or communications system for a neural probe, the interface or communications system comprising at least one probe interface, an optical communications interface and a processing system. The at least one probe interface is configured to interface with at least one neural probe so as to receive data collected by the probe. The processing system is configured to process the data from the at least one probe interface and provide the processed data to the optical communications interface. The optical communications interface is configured to communicate the processed data to a remote device, e.g. using optical wireless communications. The optical communications interface has the large bandwidth available that will allow the scaling up of recording sites from the neural probe without resulting in undue size, weight and/or power consumption.
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公开(公告)号:US11414385B2
公开(公告)日:2022-08-16
申请号:US16063877
申请日:2016-12-20
Applicant: The University of Chicago , University of Leeds , The J. Craig Venter Institute , Institute For Systems Biology , U.S. Government, as represented by The Secretary of The Army Medical Command (MEDCOM) , The University of Strathclyde
Inventor: Rima McLeod , Martin McPhillie , Colin W. G. Fishwick , Hernan Alejandro Lorenzi , Kai Wang , Taek-Kyun Kim , Yong Zhou , Leroy E. Hood , Ying Zhou , Kamal El Bissati , Mark Hickman , QiGui Li , Craig Roberts
IPC: C07D215/233 , A61P33/06 , C07D401/12 , C07D405/12 , C07D471/04 , C07D487/04
Abstract: Disclosed herein; are novel compounds for treating apicomplexan parasite related disorders, methods for their use; cell line and non-human animal models of the dormant parasite phenotype and methods for their use in identifying new drugs to treat apicomplexan parasite related disorders, and biomarkers to identify disease due to the parasite and its response to treatment.
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公开(公告)号:US20210236670A1
公开(公告)日:2021-08-05
申请号:US17178155
申请日:2021-02-17
Applicant: University of Strathclyde
Inventor: John Galloway Anderson , Michelle Maclean , Gerald Alexander Woolsey , Scott John MacGregor
Abstract: A method for inactivating medically important Gram-positive bacteria including Methicillin-resistant Staphylococcus aureus (MRSA), Coagulase-Negative Staphylococcus (CONS), Streptococcus, Enterococcus and Clostridium species, comprising exposure to visible light, and in particular light within the wavelength range 400-500 nm.
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公开(公告)号:US11021516B2
公开(公告)日:2021-06-01
申请号:US16332231
申请日:2017-09-11
Applicant: Research Foundation of the City University of New York , University of Strathclyde , Carnegie Mellon University
Inventor: Rein V. Ulijn , Ayala Lampel , Tell Tuttle , Gary Scott , Scott McPhee , Christopher Bettinger
Abstract: A self-assembling peptide is provided that is enzymatically oxidized to form a polymeric pigment. The monomeric peptide has three amino acids (tyrosine (Y), one phenylalanine (F), and one aspartic acid (D) or one lysine (K)) and, following self-assembly and treatment with a tyrosinase enzyme oxidizes and polymerizes into a material with predetermined properties.
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公开(公告)号:US10849768B2
公开(公告)日:2020-12-01
申请号:US15557294
申请日:2016-03-11
Applicant: University of Strathclyde
Inventor: Arjan Buis
Abstract: A prosthesis socket casting device having a housing and a flexible membrane for receiving a residual limb, the housing and the membrane defining a cavity for containing a fluid. Within the housing are means that are a function of the patient's weight for altering the distribution of the reactive fluid pressure applied when the residual limb is received within the membrane. In a preferred embodiment, the altering means comprise a movable piston that is provided at a lower end of the housing.
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40.
公开(公告)号:US20200281796A1
公开(公告)日:2020-09-10
申请号:US16652520
申请日:2018-10-02
Applicant: University of Strathclyde
Inventor: Heba Lakany , Lijo Chacko-Varughese
Abstract: An apparatus (10) for the rehabilitation, assistance and/or augmentation of arm strength in a user (U) comprises a support arrangement (12) for supporting the apparatus (10) on the user (U), a linkage arrangement (14) coupled to the support arrangement (12) and for coupling to an arm (A) of the user (U), and an actuation arrangement (16) for operating the linkage arrangement (14) and thereby manipulating the user's arm (A) in response to a user input signal.
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