Abstract:
4-R.sup.4 -R.sup.5 -2-Saccharinylmethyl heterocyclic carboxylates, useful in the treatment of degenerative diseases, are prepared by reacting a 4-R.sup.4 -R.sup.5 -2-halomethylsaccharin with either a heterocyclic carboxylic acid in the presence of an acid-acceptor or the alkali metal salt of a heterocyclic carboxylic acid.
Abstract:
Substituted N-cycloalkylmethyl-1H-pyrazolo[3,4-b]quinolin-4-amines, pharmaceutical compositions containing them and methods for a) effecting c-GMP-phosphodiesterase inhibition, b) treating heart failure and/or hypertension, c) reversing or reducing nitrate-induced tolerance and d) treating angina pectoris, congestive heart disease and myocardial infarction utilizing them.
Abstract:
A garbled circuit is generated for a client in a leakage-resilient manner with a reduced memory requirement. The garbled circuit is used for secure function evaluation between the client and a server. The garbled circuit is generated with a reduced storage requirement by obtaining a token from the server; querying the token gate-by-gate, wherein for each gate of the garbled circuit, the token generates new wire garblings and stores them with the client using a Stream Cipher and interacts with the leakage-protected area to generate a garbled table for the gate; and receiving the garbled circuit from the token. The token comprises a leakage-protected area. The Stream Cipher is leakage-resilient and can be a symmetric-key cryptographic primitive that has a secret key as an input and generates an unbounded stream of pseudorandom bits as an output. The number of evaluations of the Stream Cipher is kept to a substantial minimum. For example, the Stream Cipher can execute with a same key only twice, such as only once for an encryption and only once for a decryption.
Abstract:
Described herein are novel acetal compounds capable as nucleating agents for polyolefins. The present invention relates to such compounds synthesized by reacting aromatic aldehydes with polyols and further, to the achievement of high crystallization temperatures in polypropylene compositions upon dispersal therein of formulations containing one or more of the said acetal compounds.
Abstract:
A garbled circuit is generated for a client in a leakage-resilient manner with a reduced memory requirement. The garbled circuit is used for secure function evaluation between the client and a server. The garbled circuit is generated with a reduced storage requirement by obtaining a token from the server; querying the token gate-by-gate, wherein for each gate of the garbled circuit, the token generates new wire garblings and stores them with the client using a Stream Cipher and interacts with the leakage-protected area to generate a garbled table for the gate; and receiving the garbled circuit from the token. The token comprises a leakage-protected area. The Stream Cipher is leakage-resilient and can be a symmetric-key cryptographic primitive that has a secret key as an input and generates an unbounded stream of pseudorandom bits as an output. The number of evaluations of the Stream Cipher is kept to a substantial minimum.
Abstract:
Solid dispersions of stable, amorphous opioid antagonists, particularly [[2(S)-[[4(R)-(3-hydroxyphenyl)-3(R),4-dimethyl-piperidinyl]methyl]-1-oxo-3-phenylpropyl]amino]acetic acid, with improved water solubility and bioavailability are disclosed. Also disclosed are methods of preventing or treating a side effect associated with an opioid. In addition, methods of treating or preventing pain, ileus, and opioid bowel dysfunction are disclosed.
Abstract:
There is provided a system and method of providing program tracking information. An exemplary method comprises compiling a program into a plurality of instruction bundles. The exemplary method also comprises placing an instruction to store program tracking information in a local path table or a global path table into at least one of the plurality of instruction bundles.
Abstract:
Embodiments of the invention relate to exceptions. In a Java embodiment, if the count of a program statement that causes the exception reaches a threshold, then the Java Virtual Machine (JVM) searches for the throw statement corresponding to that program statement. The JVM then identifies the catch clause corresponding to the throw statement, and depending on implementations, the JVM may replace the throw statement with the catch block or replace the throw statement with a jump to the catch block. As a result, in both situations, program execution, when being supposed to execute the throw statement, executes instructions of the catch block, and avoids execution of the throw statement that would invoke the exception handler, which improves system performance.
Abstract:
A technique for reducing non-local access, in dynamically generated code that resides in a code buffer of a NUMA computer system including multiple nodes, for improving overall performance of dynamic optimization systems. In one example embodiment, this is accomplished by partitioning the code buffer into multiple smaller code buffers and assigning each of the multiple smaller code buffers to one of the multiple nodes. Statically determining which methods in the generated code are executed by a thread and then to place those methods in associated one of the multiple smaller code buffers to reduce memory latencies introduced by non-local accesses.
Abstract:
Single step process for the preparation of lower α-alkene polymerisation heterogeneous solid catalyst, wherein the procatalyst is obtained by reacting organomagnesium precursor and titanium tetrahalide or titanium haloalkoxo species of the formula Ti(OR)m Xn, with a hydrocarbon or halohydrocarbon solvent and internal electron donor and optionally an acid halide under microwave irradiation of 300 to 1200 W. The mole ratio of the organomagnesium precursor to the titanium tetrachloride or titanium haloalko species is 1:6 to 1:20 and the mole ratios of the electron donor and acid halide to titanium is 0.3 to 1.5 and 0.02 to 0.2, respectively.