Cardiac function comprising implantation of embryonic stem cell in which differentiation has been initiated
    31.
    发明授权
    Cardiac function comprising implantation of embryonic stem cell in which differentiation has been initiated 失效
    心脏功能包括植入已经开始分化的胚胎干细胞

    公开(公告)号:US06534052B1

    公开(公告)日:2003-03-18

    申请号:US09655124

    申请日:2000-09-05

    IPC分类号: A01N6300

    摘要: The present invention is a method for markedly improving cardiac function and repairing heart tissue in a living mammalian subject after the occurrence of a myocardial infarction. The method is a surgical technique which introduces and implants mammalian embryonic stem cells into the infarcted area of the myocardium. After implantation, the embryonic stem cells form stable grafts and survive indefinitely within the infarcted area of the heart in the living host. The demonstrated beneficial effects of the method include a decreased infarcted area and improved cardiac function as assessed by hemodynamic and echocardiographic measurements.

    摘要翻译: 本发明是在心肌梗塞发生后,显着改善活体哺乳动物受试者的心脏功能和修复心脏组织的方法。 该方法是将哺乳动物胚胎干细胞引入并植入心肌梗塞区域的手术技术。 植入后,胚胎干细胞形成稳定的移植物并在生物体内的心脏梗死区域内无限期地存活。 所述方法的有益效果包括通过血液动力学和超声心动图测量评估的梗塞面积减少和心脏功能改善。

    PROCESSOR BASED LOGIC SIMULATION ACCELERATION AND EMULATION SYSTEM

    公开(公告)号:US20220091907A1

    公开(公告)日:2022-03-24

    申请号:US17448216

    申请日:2021-09-21

    发明人: Yong FU

    IPC分类号: G06F9/52 G06F9/50

    摘要: An emulation and simulation acceleration system includes a plurality of processors, wherein each of the plurality of processors is configured to run a separate simulation task in a parallel manner. Each of the plurality of processors includes a local memory for instructions and data, a memory space for saving received data from other processors of the plurality of processors. The system includes a plurality of connection channels between each processor of the plurality of processors, wherein each of the plurality of connection channels is either virtual or physical, and each of the plurality of connection channels extends through computer hardware or memory mapping. The system includes a plurality of system interfaces configured to interface with other systems for expansion to a larger system or to connect with external target system. Each of the plurality of system interfaces contains a virtual interface and a physical interface for connecting with other simulators.

    BINDING ASSEMBLY WITH ANTI-ESCAPE TENSION SETTINGS FOR CLIPLESS BICYCLE PEDAL

    公开(公告)号:US20210394862A1

    公开(公告)日:2021-12-23

    申请号:US16908761

    申请日:2020-06-23

    申请人: Yong-Fu Chen

    发明人: Yong-Fu Chen

    IPC分类号: B62M3/08

    摘要: The binding assembly includes a fixed binding, an adjustable binding, two torsion springs, an adjusting nut and an adjusting bolt. The fixed binding has a bow portion, a pair of stoppers and a pair of pivoting portions. The pivoting portions are passed by a pivot. The adjustable binding has an adjusting base plate and a pair of pivoting plates. The pivoting plates are passed by the pivot. Each torsion spring has an upper end and a lower end and is put around the pivot. The lower ends are stopped by the stoppers. The adjusting nut has a threaded hole and two shoulders separately abutting against the two upper ends. The adjusting bolt has a head and a threaded rod with an enlarged end. The threaded rod passes through the adjusting base plate and screws with the threaded hole. The enlarged end projects from the threaded hole and cannot escape.

    Cleat for racing bicycle shoe
    34.
    发明授权

    公开(公告)号:US10800483B2

    公开(公告)日:2020-10-13

    申请号:US16137732

    申请日:2018-09-21

    申请人: Yong-Fu Chen

    发明人: Yong-Fu Chen

    IPC分类号: B62M3/08 A43B5/14

    摘要: Disclosed is a cleat with an adjustable pad. The cleat includes a cleat body, an anti-slip buffer and a support base. The cleat body has three fixing holes and a central hole among the three fixing holes. A top side of the central hole is formed with a recess. The recess has a front portion and a rear portion. The central is located in the front portion. The anti-slip buffer is of a hat shape corresponding to the central hole and capable of selectively being placed in the central hole in different directions to form two protrudent heights. The support base is of a shape corresponding to the recess and capable of selectively being placed in the recess in different directions to adjustably support the anti-slip buffer.

    Molecular transporter compositions comprising dendrimeric oligoguanidine with a tri-functional core that facilitates delivery into cells in vivo
    35.
    发明授权
    Molecular transporter compositions comprising dendrimeric oligoguanidine with a tri-functional core that facilitates delivery into cells in vivo 有权
    分子转运蛋白组合物包含具有三官能核心的树状聚合寡核苷酸,其有助于体内递送到细胞中

    公开(公告)号:US08637492B2

    公开(公告)日:2014-01-28

    申请号:US13317530

    申请日:2011-10-20

    申请人: Yong-Fu Li

    发明人: Yong-Fu Li

    IPC分类号: A61K31/675

    摘要: Novel molecular transporter compositions and their use for transporting bioactive substances into cells in living animals are disclosed. To afford in vivo delivery, the composition is covalently linked to the bioactive substance and the resultant composite structure is introduced into the subject. The transporter composition includes multiple guanidine moieties on a dendrimeric scaffold having a tri-functional core. The tri-functional core is a phosphorodiamidate or phosphoramide moiety.

    摘要翻译: 公开了新型分子转运体组合物及其将生物活性物质输送到活体动物细胞中的用途。 为了提供体内递送,组合物与生物活性物质共价连接,并将所得复合结构引入受试者。 转运蛋白组合物在具有三官能核心的树枝状聚合物支架上包含多个胍部分。 三官能核心是磷酰二胺或磷酰胺部分。

    Light string system
    36.
    发明授权
    Light string system 有权
    灯串系统

    公开(公告)号:US08419455B2

    公开(公告)日:2013-04-16

    申请号:US13560602

    申请日:2012-07-27

    IPC分类号: H01R29/00

    CPC分类号: H01R31/08 H01R33/09 H01R33/96

    摘要: A lamp system used in a light string system comprises a light assembly and a socket assembly. The light assembly comprises a light source, a base in communication with the light source, and a bypass activating system. The socket assembly comprises a socket adapted to receive the light assembly and a bypass mechanism having a first position and a second position. The bypass mechanism is in the first position when the light assembly is not seated in the socket assembly. When the bypass mechanism in the first position, current flows across the bypass mechanism. When the light assembly is inserted into the socket assembly, the bypass activating system of the light assembly moves the bypass mechanism into the second position, and current flows through the light source instead of the bypass mechanism.

    摘要翻译: 用于灯串系统的灯系统包括灯组件和插座组件。 灯组件包括光源,与光源连通的基座和旁路启动系统。 插座组件包括适于容纳灯组件的插座和具有第一位置和第二位置的旁路机构。 当灯组件未安装在插座组件中时,旁路机构处于第一位置。 当旁路机构处于第一位置时,电流流过旁路机构。 当灯组件插入插座组件中时,灯组件的旁路启动系统将旁路机构移动到第二位置,并且电流流过光源而不是旁路机构。

    CARD EDGE CONNECTOR
    37.
    发明申请
    CARD EDGE CONNECTOR 有权
    卡边缘连接器

    公开(公告)号:US20130090016A1

    公开(公告)日:2013-04-11

    申请号:US13346509

    申请日:2012-01-09

    申请人: Yong Fu Wang

    发明人: Yong Fu Wang

    IPC分类号: H01R24/20

    摘要: A card edge connector includes an insulating body having a base body, multiple first terminals, and multiple second terminals. A first body and a second body extend from a front end of the base body sequentially from bottom to top. Multiple recessed first receiving slots are disposed at the first body. A recessed first retaining slot is disposed at the first body and a side wall of each of the first receiving slots. Each of the first terminals has a first retaining portion retained in the first retaining slot with a first connecting portion bent and extends laterally thereof. A first elastic section extends forwards from the first connecting portion and located in the first receiving slot. A first contact arm extends forwards from the rear end of the first elastic section and has a first contact portion which enters the first insertion space.

    摘要翻译: 卡缘连接器包括具有基体,多个第一端子和多个第二端子的绝缘体。 第一主体和第二主体从底部的前端顺序地从底部延伸到顶部。 多个凹进的第一接收槽设置在第一主体处。 凹陷的第一保持槽设置在第一主体和每个第一接收槽的侧壁。 每个第一端子具有保持在第一保持狭槽中的第一保持部分,第一连接部分弯曲并横向延伸。 第一弹性部分从第一连​​接部分向​​前延伸并且位于第一接收槽中。 第一接触臂从第一弹性部分的后端向前延伸并且具有进入第一插入空间的第一接触部分。

    Molecular transporter compositions comprising dendrimeric oligoguanidine with a tri-functional core that facilitates delivery into cells in vivo
    38.
    发明申请
    Molecular transporter compositions comprising dendrimeric oligoguanidine with a tri-functional core that facilitates delivery into cells in vivo 有权
    分子转运蛋白组合物包含具有三官能核心的树状聚合寡核苷酸,其有助于体内递送到细胞中

    公开(公告)号:US20120035358A1

    公开(公告)日:2012-02-09

    申请号:US13317530

    申请日:2011-10-20

    申请人: Yong-Fu Li

    发明人: Yong-Fu Li

    IPC分类号: C07F9/6558

    摘要: Novel molecular transporter compositions and their use for transporting bioactive substances into cells in living animals are disclosed. To afford in vivo delivery, the composition is covalently linked to the bioactive substance and the resultant composite structure is introduced into the subject. The transporter composition includes multiple guanidine moieties on a dendrimeric scaffold having a tri-functional core. The tri-functional core is a phosphorodiamidate or phosphoramide moiety.

    摘要翻译: 公开了新型分子转运体组合物及其将生物活性物质输送到活体动物细胞中的用途。 为了提供体内递送,组合物与生物活性物质共价连接,并将所得复合结构引入受试者。 转运蛋白组合物在具有三官能核心的树枝状聚合物支架上包含多个胍部分。 三官能核心是磷酰二胺或磷酰胺部分。

    CONNECTOR SYSTEM
    39.
    发明申请
    CONNECTOR SYSTEM 有权
    连接器系统

    公开(公告)号:US20120009360A1

    公开(公告)日:2012-01-12

    申请号:US12982015

    申请日:2010-12-30

    IPC分类号: A47G33/06 B23P11/00

    摘要: A connector system facilitates the connection of a first tree trunk to a second tree trunk of an artificial tree system, and further protects one or more ends of a trunk when, for example, the artificial tree system is being shipped or stored. The connector system comprises a sleeve. The sleeve comprises a cylindrical shaped body. The outer of the body has a uniform cylindrical shape. The interior of the sleeve has different diameters at its top and bottom. The interior includes a notch or shoulder. The shoulder is in proximity to the top end of the sleeve. The sleeve further comprises a cutout for assisting with connecting and securing the trunks together.

    摘要翻译: 连接器系统有助于将第一树干连接到人造树系统的第二树干,并且当例如人造树系统正在运输或存储时,进一步保护干线的一端或多端。 连接器系统包括套筒。 套筒包括圆柱形的主体。 身体的外部具有均匀的圆柱形状。 套筒的内部在其顶部和底部具有不同的直径。 内部包括凹口或肩部。 肩膀靠近套筒的顶端。 套筒还包括用于辅助将树干连接并固定在一起的切口。

    Molecular transporter compositions comprising dendrimeric oligoguanidine with a triazine core that facilitate delivery into cells in vivo
    40.
    发明授权
    Molecular transporter compositions comprising dendrimeric oligoguanidine with a triazine core that facilitate delivery into cells in vivo 有权
    分子转运蛋白组合物,其包含具有三嗪核心的树状聚寡聚核苷酸,其有助于体内递送到细胞中

    公开(公告)号:US07935816B2

    公开(公告)日:2011-05-03

    申请号:US11977800

    申请日:2007-10-25

    申请人: Yong-Fu Li

    发明人: Yong-Fu Li

    摘要: Preparations of novel molecular transporter compositions and their use for transporting bioactive substances into cells in living animals are disclosed. To afford in vivo delivery, the composition is covalently linked to the bioactive substance and the resultant composite structure is introduced into the subject. The transporter composition includes multiple guanidine moieties on a dendrimeric scaffold having a triazine core.

    摘要翻译: 公开了新型分子转运体组合物的制备及其将生物活性物质输送到活体动物细胞中的用途。 为了提供体内递送,组合物与生物活性物质共价连接,并将所得复合结构引入受试者。 转运蛋白组合物在具有三嗪核心的树枝状聚合物支架上包含多个胍部分。