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    CLAY-BASED HEMOSTATIC AGENTS AND DEVICES FOR THE DELIVERY THEREOF
    32.
    发明申请
    CLAY-BASED HEMOSTATIC AGENTS AND DEVICES FOR THE DELIVERY THEREOF 有权
    基于粘土的催化剂及其输送装置

    公开(公告)号：US20140171848A1

    公开(公告)日：2014-06-19

    申请号：US14185873

    申请日：2014-02-20

    申请人： Z-Medica, LLC

    发明人： Raymond J. Huey ,  Denny Lo ,  Daniel J. Burns ,  Giacomo Basadonna ,  Francis X. Hursey

    IPC分类号： A61L15/18 ,  A61L15/42

    CPC分类号： A61L15/44 ,  A61F13/00012 ,  A61F13/00063 ,  A61L15/18 ,  A61L15/28 ,  A61L15/425 ,  A61L2300/404 ,  A61L2300/406 ,  A61L2400/04 ,  A61L2400/16

    摘要： A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

    摘要翻译： 用于促进血液凝结的止血装置包括纱布基底，布置在纱布基底上的粘土材料，以及布置在纱布基底上以粘合粘土材料的多元醇，例如甘油等。 当该装置用于治疗流血的伤口时，至少一部分粘土材料与从伤口发出的血液接触以引起凝血。 可以应用于流血伤口以促进血液凝结的绷带包括安装在其上的柔性基底和纱布基底。 纱布基材包括粘土材料和多元醇。 止血海绵还包括纱布基底和止血材料和多元醇在基底的第一表面上的分散体。

    Hemostatic devices
    34.
    发明授权
    Hemostatic devices 有权

    公开(公告)号：US10960100B2

    公开(公告)日：2021-03-30

    申请号：US15429935

    申请日：2017-02-10

    申请人： Z-Medica, LLC

    发明人： Dina Dubey ,  Denny Lo

    IPC分类号： A61L15/16 ,  A61L15/28 ,  A61L15/44 ,  A61L15/46 ,  A61L15/18

    摘要： Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon.

    Clay-based hemostatic agents and devices for the delivery thereof
    36.
    发明授权
    Clay-based hemostatic agents and devices for the delivery thereof 有权
    基于粘土的止血剂和用于输送的装置

    公开(公告)号：US08784876B2

    公开(公告)日：2014-07-22

    申请号：US13911616

    申请日：2013-06-06

    申请人： Z-Medica, LLC

    发明人： Raymond J. Huey ,  Denny Lo ,  Daniel J. Burns ,  Giacomo Basadonna ,  Francis X. Hursey

    IPC分类号： A61L15/14 ,  A61K9/14 ,  A61F13/00 ,  A61L15/16 ,  A61L15/18

    CPC分类号： A61F13/534 ,  A61L15/18 ,  A61L15/44 ,  A61L2300/102 ,  A61L2300/402 ,  A61L2300/404 ,  A61L2300/41 ,  A61L2300/418 ,  A61L2400/04

    摘要： A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

    摘要翻译： 用于促进血液凝结的装置包括颗粒形式的粘土材料和用于容纳粘土材料的容器。 容器的至少一部分由网格限定。 另一种装置包括纱布基底和布置在纱布基底上的粘土材料。 另一种装置是包括基底，安装在基底上的网和保留在网中的粘土材料颗粒的绷带。 止血海绵包括基材，设置在基材的第一表面上的止血材料和设置在基材的第二表面上的脱模剂。 脱模剂设置在基材的卷绕接触表面上。 当治疗出血的伤口时，止血海绵的施用使至少一部分止血材料通过脱模剂和通过基底与血液接触。