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公开(公告)号：US3459754A
公开(公告)日：1969-08-05
申请号：US3459754D
申请日：1967-02-09
Applicant: AMERICAN HOME PROD
Inventor： BELL STANLEY C
IPC: C07D487/04 , C07D51/48 , A61K21/00 , A61K27/00
CPC classification number: C07D487/04 , Y10S514/912
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32.发明授权5-(m-sulfamoylphenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-one 失效5-（M-磺酰基苯基）-1,3-二氢-2H-哒嗪-2,3-苯并二吖庚因-2-酮
公开(公告)号：US3458501A
公开(公告)日：1969-07-29
申请号：US3458501D
申请日：1967-02-09
Applicant: AMERICAN HOME PROD
Inventor： BELL STANLEY C , CONKLIN GEORGE L
IPC: A61K31/55 , C07D243/24 , C07D53/06 , A61K27/00
CPC classification number: C07D243/24 , A61K31/55
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公开(公告)号：US3452041A
公开(公告)日：1969-06-24
申请号：US3452041D
申请日：1965-05-19
Applicant: AMERICAN HOME PROD
Inventor： BELL STANLEY C , CONKLIN GEORGE L
IPC: C07D233/72 , C07D233/80 , C07D233/88 , C07D295/13 , C07D49/32 , A61K27/00
CPC classification number: C07D295/13 , C07D233/80 , C07D233/88
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公开(公告)号：US3417101A
公开(公告)日：1968-12-17
申请号：US65697467
申请日：1967-01-10
Applicant: AMERICAN HOME PROD
Inventor： BELL STANLEY C , CHILDRESS SCOTT J
IPC: C07D219/08 , C07D311/86
CPC classification number: C07D311/86 , C07C2603/18 , C07D219/08
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35.发明授权Intermediates for the preparation of 1, 3-dihydro-5-aryl-2h-1, 4-benzodiazepin-2-ones 4-oxides 失效用于制备1,3-二氢-5-芳基-2h-1,4-苯并二氮杂-4-氧化物的中间体
公开(公告)号：US3401200A
公开(公告)日：1968-09-10
申请号：US64490067
申请日：1967-06-09
Applicant: AMERICAN HOME PROD
Inventor： BELL STANLEY C
IPC: C07C233/00 , C07D213/50 , C07D243/24 , C07D243/28 , C07D307/46 , C07D333/22
CPC classification number: C07D243/24 , C07C233/00 , C07D213/50 , C07D307/46 , C07D333/22
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Patent Agency Ranking36.发明授权
公开(公告)号：US3324114A
公开(公告)日：1967-06-06
申请号：US37828464
申请日：1964-06-26
Applicant: AMERICAN HOME PROD
Inventor： BELL STANLEY C
IPC: B25B15/00 , C07D243/24 , C07D243/26 , C07D409/04 , F16B23/00
CPC classification number: B25B15/008 , C07D243/24 , C07D409/04
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37.发明授权Process for the preparation of hexahydro-1, 3-dimethyl-4-phenylazepine-4-carboxylic acid, ethyl ester 失效制备六氢-1,3-二甲基-4-苯吖庚因-4-甲酸乙酯的方法
公开(公告)号：US3316244A
公开(公告)日：1967-04-25
申请号：US37308964
申请日：1964-06-05
Applicant: AMERICAN HOME PROD
Inventor： BELL STANLEY C , CHILDRESS SCOTT J
CPC classification number: C07D295/088
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38.发明授权2-alkylideneamino-2h-1, 2, 4-benzothiadiazine 1, 1-dioxides and related compounds 失效2-亚烷基氨基-2h-1,2,4-苯并噻二嗪1,1-二氧化物及相关化合物
公开(公告)号：US3314950A
公开(公告)日：1967-04-18
申请号：US34483064
申请日：1964-02-14
Applicant: AMERICAN HOME PROD
Inventor： WEI PETER H L , BELL STANLEY C
IPC: C07D285/24
CPC classification number: C07D285/24
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39.发明授权Process for preparing 1, 3-dihydro-5-aryl-2h-1, 4-benzodiazepin-2-one 4-oxides 失效制备1,3-二氢-5-芳基-2h-1,4-苯并二氮杂-1,1-二氧化物的方法
公开(公告)号：US3313805A
公开(公告)日：1967-04-11
申请号：US55927566
申请日：1966-06-21
Applicant: AMERICAN HOME PROD
Inventor： BELL STANLEY C
IPC: C07C233/00 , C07D243/24
CPC classification number: C07D243/24 , C07C233/00
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40.发明授权1,2-Dihydro- and 1,2,3,4-tetrahydro-1-oxo-3-isoquinolinecarboxylic acid derivatives as anti-allergic agents 失效1,2-二氢 - 和1,2,3,4-四氢-1-氧代-3-异喹啉羧酸衍生物作为抗过敏剂
公开(公告)号：US3928612A
公开(公告)日：1975-12-23
申请号：US51134174
申请日：1974-10-02
Applicant: AMERICAN HOME PROD
Inventor： SELLSTEDT JOHN H , GUINOSSO CHARLES J , BELL STANLEY C
IPC: A61K31/47 , C07D217/26
CPC classification number: C07D217/26 , A61K31/47 , Y10S514/826
Abstract: Atopic allergic reactions, such as hives asthma, hay fever, allergic rhinitis, urticaria, conjunctivitis, food allergies, and the like, are prevented in a sensitive, warm-blooded animal by administration of a compound of the formula:
IN WHICH R1 is -H alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, hydroxyalkoxy of 2 to 6 carbon atoms, halo, -NO2, -NH2, dialkylamino having from 1 to 6 carbon atoms in each alkyl group, -CONH2, -SO2NH2, carbalkoxy having from 2 to 6 carbon atoms or alkylthio of 1 to 6 carbon atoms; and R2 is -H, alkyl of 1 to 6 carbon atoms, an alkali metal cation or the ammonium cation, WHEREIN THE DOTTED LINE APPEARING IN THE STRUCTURAL FORMULA REPRESENTS OPTIONAL UNSATURATION.Abstract translation: 在敏感的温血动物中通过施用下式化合物来防止特应性过敏反应，例如荨麻疹哮喘，花粉症，过敏性鼻炎，荨麻疹，结膜炎，食物过敏等。
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