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公开(公告)号：US07192434B2
公开(公告)日：2007-03-20
申请号：US10132562
申请日：2002-04-25
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B17/12022 , A61B17/12172 , A61B17/221 , A61B2017/00867 , A61B2017/22045 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0008 , A61F2230/0067 , A61F2230/008 , A61F2230/0093 , A61M25/0074 , A61M25/0082 , A61M25/09 , A61M2025/0079 , A61M2025/09183
摘要： An embolic protection device or system for use in a lumen of a vessel in a patient's vascular system. The device filters debris and blood clots in a body lumen and/or prevents them from moving distally from a treatment site in a vessel and causing emboli. The device may include a filter placed distally of the treatment site. The device may include an occlusive element placed either distally or proximally of the treatment site.
摘要翻译： 一种用于患者血管系统中血管内腔的栓塞保护装置或系统。 该装置过滤器体内的碎屑和血块，和/或阻止它们远离血管内的治疗部位并引起栓塞。 该装置可以包括放置在治疗部位的远侧的过滤器。 该装置可以包括放置在治疗部位的远侧或近端的闭塞元件。
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公开(公告)号：US07166120B2
公开(公告)日：2007-01-23
申请号：US10194734
申请日：2002-07-12
申请人： Richard S. Kusleika
发明人： Richard S. Kusleika
CPC分类号： A61B17/221 , A61B2017/22067 , A61F2/013 , A61F2/958 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0071 , A61F2230/008
摘要： A device, method, and system of deploying an embolic protection device at a location distal to a treatment site in a vessel of a patient. A delivery catheter is encircled by a sealing member which is expandable from a delivery configuration to a deployed configuration. The device creates a seal to prevent the flow of blood during the treatment of vascular disease. A distal protection element is delivered by the delivery catheter and deployed to filter or remove embolic debris.
摘要翻译： 一种在患者血管中远处治疗部位的位置部署栓塞保护装置的装置，方法和系统。 输送导管被密封构件包围，该密封构件从输送构型可展开到展开构型。 该装置产生密封以防止血管疾病治疗过程中的血液流动。 远端保护元件由输送导管输送并展开以过滤或去除栓塞碎片。
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公开(公告)号：US06911037B2
公开(公告)日：2005-06-28
申请号：US10093091
申请日：2002-03-06
CPC分类号： A61B17/0057 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00623
摘要： The present invention provides a septal defect closure device (10) having a first occluding disk (30) having a first flexible membrane (32) attached to a first frame (34) and a second occluding disk (20) having a second flexible membrane (22) attached to a separate second frame (24). The first frame has at least two outwardly extending loops joined to one another by flexible joints. These loops are attached to the first membrane to define taut fabric petals when the first disk is in a deployed configuration. A central portion of the first membrane is joined to the central portion of the second membrane via a joining segment, which may comprise a conjoint disk. The flexible joints of the first frame are received within the joining segment. This septal defect closure device provides enhanced retrievability.
摘要翻译： 本发明提供了一种隔膜缺损闭合装置（10），其具有第一闭塞盘（30），该第一闭塞盘具有附接到第一框架（34）的第一柔性膜（32）和具有第二柔性膜的第二闭塞盘（20） 22）连接到单独的第二框架（24）。 第一框架具有通过柔性接头彼此连接的至少两个向外延伸的环。 当第一个磁盘处于部署配置中时，这些环连接到第一个膜以确定拉紧的织物瓣。 第一膜的中心部分经由连接段连接到第二膜的中心部分，该连接段可以包括联合盘。 第一框架的柔性接头被接收在接合段内。 该间隔缺损闭合装置提供增强的可检索性。
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公开(公告)号：US06773448B2
公开(公告)日：2004-08-10
申请号：US10093572
申请日：2002-03-08
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0008 , A61F2230/0069 , A61F2230/008 , A61F2230/0093 , A61M25/09 , A61M2025/0079 , A61M2025/09183
摘要： A distal protection device for use in a body lumen. The device includes a functional element which may be a filter or an occlusive element. The device includes means for controlling the movement and placement of the functional element along a guidewire. Motion of the guidewire can be independent of the motion of the functional element.
摘要翻译： 用于体腔内的远端保护装置。 该装置包括可以是过滤器或闭塞元件的功能元件。 该装置包括用于控制沿着导丝的功能元件的移动和放置的装置。 导丝的运动可以独立于功能元件的运动。
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公开(公告)号：US06733474B2
公开(公告)日：2004-05-11
申请号：US09815144
申请日：2001-03-22
申请人： Richard S. Kusleika
发明人： Richard S. Kusleika
IPC分类号： A61M3100
CPC分类号： A61M25/104 , A61M25/0032 , A61M25/007 , A61M25/1011 , A61M2025/0057 , A61M2025/1013 , A61M2025/105
摘要： A combination dilatation and drug delivery device includes a flexible catheter, a drug delivery sheath mounted to a distal end region of the catheter and a dilatation balloon also mounted to the catheter and contained within a compartment formed by the sheath. The sheath is radially expandable by supplying a liquid therapeutic agent to the compartment under a moderate pressure. The dilatation balloon is expandable by providing a dilatation fluid to the balloon under a much higher pressure. The sheath can be formed of a highly elastic material or can be made quite thin, and in either case is mounted independently of the dilatation balloon. Thus when radially expanded, the sheath is moved into a conforming contact with surrounding vascular tissue. The conforming contact protects tissue and the therapeutic agent from exposure to blood, and more effectively confines the therapeutic agent to the intended treatment area. The sheath either is naturally porous or is provided with multiple pores, whereby the therapeutic agent perfuses through the sheath into the surrounding tissue.
摘要翻译： 组合扩张和药物递送装置包括柔性导管，安装到导管的远端区域的药物递送护套和还安装到导管并且容纳在由护套形成的隔室内的扩张球囊。 通过在中等压力下将液体治疗剂供应到隔室，护套可径向扩张。 通过在高得多的压力下向球囊提供膨胀流体来扩张膨胀气囊。 护套可以由高弹性材料形成，或者可以制成相当薄，并且在任一种情况下均可独立于膨胀气囊安装。 因此，当径向膨胀时，护套被移动到与周围血管组织的符合接触。 合适的接触保护组织和治疗剂免于接触血液，并且更有效地将治疗剂限制在预期的治疗区域。 护套是天然多孔的或设置有多个孔，由此治疗剂通过治疗护套灌注到周围的组织中。
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公开(公告)号：USD464730S1
公开(公告)日：2002-10-22
申请号：US29113275
申请日：1999-11-02
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公开(公告)号：US08579958B2
公开(公告)日：2013-11-12
申请号：US13614035
申请日：2012-09-13
申请人： Richard S. Kusleika
发明人： Richard S. Kusleika
IPC分类号： A61F2/82
摘要： A stent delivery assembly is provided that includes a microcatheter, a delivery tube, a stent, and an elongate release member. The stent can have a first end that is (i) disposed within a delivery tube lumen and (ii) constrained by the delivery tube from radially expanding beyond a delivery tube lumen diameter. The stent can have a second end that is (i) disposed outside of a delivery tube distal end and (ii) substantially radially unconstrained by the delivery tube to expand beyond the delivery tube lumen diameter. The elongate release member can be moveable between first and second positions to engage or release the stent.
摘要翻译： 提供了一种支架输送组件，其包括微导管，输送管，支架和细长释放构件。 支架可以具有第一端，其第一端（i）设置在输送管内腔内，和（ii）由输送管约束，从而径向扩张超过输送管腔直径。 支架可以具有第二端，其第二端是（i）设置在输送管远端的外侧，以及（ii）基本上径向地不受输送管约束以扩张超过输送管腔直径。 细长释放构件可以在第一和第二位置之间移动以接合或释放支架。
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公开(公告)号：US08317850B2
公开(公告)日：2012-11-27
申请号：US12477613
申请日：2009-06-03
申请人： Richard S. Kusleika
发明人： Richard S. Kusleika
IPC分类号： A61F2/82
摘要： A delivery device includes a delivery tube having an elongate release member. An everted stent may be releasably captured by the elongate release member between the release member and the delivery tube. The captured and everted stent can be distally advanced to a target site, followed by manipulating the release member to free the captured stent. Some devices utilize distal advancement of the release member while other devices use proximal retraction of the release member to free the captured stent. Once released, the stent is free to self-expand or be expanded against the surrounding blockage and/or vessel walls. In some methods, a guide catheter or microcatheter is also included and disposed about the everted and captured stent to advance the stent, delivery tube, and release member to a location near the site to be stented.
摘要翻译： 输送装置包括具有细长释放构件的输送管。 永久性支架可以由释放构件和输送管之间的细长释放构件可释放地捕获。 捕获的和断端的支架可以远端前进到目标部位，随后操纵释放构件以释放被捕获的支架。 一些装置利用释放构件的远端前进，而其他装置使用释放构件的近端缩回以释放所捕获的支架。 一旦释放，支架可自由扩张或扩大到周围的阻塞和/或血管壁。 在一些方法中，引导导管或微导管还包括并布置在绕过和捕获的支架周围，以将支架，输送管和释放构件推进到待固定位点附近的位置。
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公开(公告)号：US20120035649A1
公开(公告)日：2012-02-09
申请号：US13270794
申请日：2011-10-11
申请人： Richard S. Kusleika
发明人： Richard S. Kusleika
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61B17/221 , A61B2017/2212 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0069
摘要： The present invention provides a method of deploying a medical filter within a channel in a patient's body and filter systems which can be used in such a method. Such a filter may include a radially expandable body 52 having an opening 56 in a proximal length thereof. In one method, the filter is urged along a length of the channel with the filter body in a radially reduced configuration. This body is expanded to substantially fill the lumen of the vessel and orient the opening in the body proximally. Body fluid is permitted to enter the filter body through the proximally oriented opening and pass distally through the distal length of the body so that the distal length of the body filters from the body fluid particulate material entrained therein. The proximal length of the body can be drawn into the retrieval catheter, thereby effectively closing the proximally oriented opening within the catheter to retain the particulate material within the enclosure. In a preferred embodiment, the filter body 52 is formed of a porous, resilient fabric having pores therein and the proximal opening 56 is at least five times the size of such pores.
摘要翻译： 本发明提供了一种在病人体内的通道内部署医疗过滤器的方法和可以用于这种方法的过滤系统。 这种过滤器可以包括在其近端具有开口56的径向可扩张体52。 在一种方法中，过滤器沿着通道的长度被推动，过滤体处于径向减小的构型。 该体膨胀以基本上填充血管的内腔并将体内的开口向近侧定向。 允许体液通过近端取向的开口进入过滤体，并通过身体的远端长度通过，使得身体的远端长度从夹带在体液颗粒物质中过滤。 身体的近端长度可以被拉入取回导管，从而有效地关闭导管内的向近侧定向的开口以将颗粒材料保持在外壳内。 在优选实施例中，过滤器主体52由其中具有孔的多孔弹性织物形成，并且近端开口56是这种孔的尺寸的至少五倍。
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公开(公告)号：US20120022634A1
公开(公告)日：2012-01-26
申请号：US13247310
申请日：2011-09-28
申请人： Richard S. Kusleika , Rick Kravik
发明人： Richard S. Kusleika , Rick Kravik
CPC分类号： A61L29/18 , A61L29/02 , A61L31/022 , A61L31/18
摘要： Medical devices made at least in part of amorphous metals or alloys are provided. Certain embodiments include filters, stents, guidewires, snares, and coils comprised of amorphous metal. Methods of forming the medical devices, including methods of shape setting amorphous metals or alloys into components of medical devices are also provided. Methods of using amorphous metal medical devices are also provided.
摘要翻译： 提供至少部分无定形金属或合金制成的医疗器械。 某些实施例包括由无定形金属组成的滤器，支架，导线，圈套和线圈。 还提供了形成医疗装置的方法，包括将非晶态金属或合金成形为医疗装置的部件的方法。 还提供了使用非晶金属医疗器械的方法。
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