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公开(公告)号:US06812706B2
公开(公告)日:2004-11-02
申请号:US10387762
申请日:2003-03-12
申请人: Jimmy Leung , Layne Howard , James Higgins , Bao Nguyen
发明人: Jimmy Leung , Layne Howard , James Higgins , Bao Nguyen
IPC分类号: G01V300
CPC分类号: G01R33/307
摘要: An NMR sample tube assembly for holding a sample comprises a sample tube, a sealing plug for sealing the sample within the sample tube, and a rotor for spinning the assembly. The plug is clamped to the sample tube by an axial force. Preferably, the sample tube has a sealing flange protruding from the sample tube exterior along an inlet region of the sample tube. A filling part of the plug is sized to maintain an air escape clearance between the filling part and the sample tube for allowing air to escape out of the sample tube as the filling part is inserted therein. The rotor is secured to a protruding sealing part of the plug and clamps the sealing part to the sealing flange. The designs allow the use of wide sample tube mouths, and reduce the amount of air bubbles present in the samples during measurements.
摘要翻译: 用于保持样品的NMR样品管组件包括样品管,用于密封样品管内的样品的密封塞和用于旋转组件的转子。 插头通过轴向力夹在样品管上。 优选地,样品管具有沿着样品管的入口区域从样品管外部突出的密封凸缘。 塞子的填充部分的尺寸设置成在填充部分和样品管之间保持空气逸出间隙,以便当填充部分插入其中时允许空气从样品管中逸出。 转子固定在插头的突出的密封部分上并将密封部分夹紧到密封凸缘上。 这些设计允许使用宽的样品管口,并且在测量期间减少样品中存在的气泡的量。
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公开(公告)号:US09688689B2
公开(公告)日:2017-06-27
申请号:US14709852
申请日:2015-05-12
申请人: Ha-Soon Choi , James Paul Lajiness , Srinivasa Reddy Natala , Bao Nguyen , Hank Michael James Petrassi , Zhicheng Wang
发明人: Ha-Soon Choi , James Paul Lajiness , Srinivasa Reddy Natala , Bao Nguyen , Hank Michael James Petrassi , Zhicheng Wang
IPC分类号: C07D493/08 , A61K31/443 , A61K31/4245 , A61K31/4155 , A61K31/506 , A61K31/34 , A61K31/4439 , A61K31/5377 , A61K31/351 , A61K31/4545 , A61K31/4525 , A61K31/497 , A61K31/444 , A61K45/06 , C07D491/18
CPC分类号: A61K31/443 , A61K31/34 , A61K31/351 , A61K31/4155 , A61K31/416 , A61K31/4245 , A61K31/4433 , A61K31/4439 , A61K31/444 , A61K31/4525 , A61K31/4545 , A61K31/497 , A61K31/506 , A61K31/5377 , A61K45/06 , A61L27/54 , A61L2300/412 , A61L2430/06 , C07D491/18 , C07D493/08 , C12N5/0655 , C12N2501/999 , C12N2506/1346
摘要: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds, and methods of using such compounds for treatment of joint damage or joint injury in a mammal, and for inducing differentiation of mesenchymal stem cells into chondrocytes.
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公开(公告)号:US20150051206A1
公开(公告)日:2015-02-19
申请号:US14241884
申请日:2012-08-29
申请人: Jon Loren , Xiaolin Li , Xiaodong Liu , Valentina Molteni , Juliet Nabakka , Bao Nguyen , Hank Michael James Petrassi , Vince Yeh , Paul Vincent Rucker
发明人: Jon Loren , Xiaolin Li , Xiaodong Liu , Valentina Molteni , Juliet Nabakka , Bao Nguyen , Hank Michael James Petrassi , Vince Yeh , Paul Vincent Rucker
IPC分类号: C07D471/04
CPC分类号: C07D471/04
摘要: The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases.
摘要翻译: 本发明提供了可用作蛋白激酶抑制剂的化合物及其药物组合物,以及使用这些化合物治疗,改善或预防与异常或失调激酶活性相关的病症的方法。 在一些实施方案中,本发明提供了使用这些化合物治疗,改善或预防涉及c-kit或c-kit和PDGFR(PDGFRα,PDGFR&bgr))激酶的异常活化的疾病或病症的方法。
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公开(公告)号:US08754071B2
公开(公告)日:2014-06-17
申请号:US14031792
申请日:2013-09-19
申请人: Valentina Molenti , Hank Michael James Petrassi , Xiaolin Li , Xiaodong Liu , Jon Loren , Juliet Nabakka , Bao Nguyen , Vince Yeh
发明人: Valentina Molenti , Hank Michael James Petrassi , Xiaolin Li , Xiaodong Liu , Jon Loren , Juliet Nabakka , Bao Nguyen , Vince Yeh
IPC分类号: A61K31/437 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61P1/00 , A61P1/16 , A61P3/00 , A61P3/10 , A61P7/00 , A61P9/12 , A61P11/00 , A61P11/02 , A61P11/06 , A61P17/00 , A61P29/00 , A61P37/00 , A61P37/08
CPC分类号: C07D491/107 , C07D471/04 , C07D491/044 , C07D491/048 , C07D498/04
摘要: The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases.
摘要翻译: 本发明提供了可用作蛋白激酶抑制剂的化合物及其药物组合物,以及使用这些化合物治疗,改善或预防与异常或失调激酶活性相关的病症的方法。 在一些实施方案中,本发明提供了使用这些化合物治疗,改善或预防涉及c-kit或c-kit和PDGFR(PDGFRα,PDGFR&bgr))激酶的异常活化的疾病或病症的方法。
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公开(公告)号:US07792075B2
公开(公告)日:2010-09-07
申请号:US11327242
申请日:2006-01-05
申请人: Tom Chin , Bao Nguyen
发明人: Tom Chin , Bao Nguyen
IPC分类号: G06F15/16
CPC分类号: H04W74/0816 , H04W52/0261 , H04W74/0866 , Y02D70/142 , Y02D70/146
摘要: A method and apparatus to perform persistence tests for a mobile station in a network are described. The apparatus includes a random number generator, a timer module, and a processor coupled to the random number generator and the timer module. A counter for the random number generator configured to count access slots is initialized. One or more random numbers are successively generated, until a value of a generated random number is lower than a first predetermined value. At the same time, the counter is successively incremented based on the number of generated random numbers. When the counter value is higher than or equal to a second predetermined value of successive iterations, or, in the alternative, when the value of the generated random number is lower than the first predetermined value, the mobile station is deactivated for a predetermined number of access slots equal to the counter value. A timer interrupt further runs subsequent to the expiration of the predetermined number of access slots. Finally, if an access probe needs to be transmitted to the network, the timer interrupt is disabled and a random access number is generated in preparation for transmission of the access probe to enable access to the network.
摘要翻译: 描述了对网络中的移动台执行持久性测试的方法和装置。 该装置包括随机数发生器,定时器模块和耦合到随机数发生器和定时器模块的处理器。 被配置为对接入时隙进行计数的随机数发生器的计数器被初始化。 连续产生一个或多个随机数,直到生成的随机数的值低于第一预定值。 同时,计数器依据生成的随机数的顺序依次递增。 当计数器值高于或等于连续迭代的第二预定值时,或者替代地,当生成的随机数的值低于第一预定值时,移动站停用预定数量的 访问时隙等于计数器值。 在预定数量的接入时隙到期之后,定时器中断进一步运行。 最后,如果接入探测器需要发送到网络,则定时器中断被禁用,随机接入号码被准备用于传输接入探测器以便能够访问网络。
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公开(公告)号:US20090300118A1
公开(公告)日:2009-12-03
申请号:US12130996
申请日:2008-05-30
申请人: Bao Nguyen , Fredi Jaramillo
发明人: Bao Nguyen , Fredi Jaramillo
IPC分类号: G06F15/16
摘要: In an embodiment of the invention, a method for subscriber auditing in a mobile messaging system can be provided. The method can include deploying a mobile messaging system for use in cooperation with a communicatively coupled e-mail server, pushing e-mail from the e-mail server to wireless devices belonging to different subscribers through the mobile messaging system, counting the subscribers and comparing a number of the subscribers to a permitted number of licensed subscribers for the mobile messaging system, and alerting an administrator of the mobile messaging system when the number of the subscribers counted crosses a threshold value less than the licensed subscribers. In one aspect of the embodiment, the threshold value can be zero thus an alert is only sent when the number of subscribers counted exceeds the permitted number of licensed subscribers.
摘要翻译: 在本发明的实施例中,可以提供在移动消息系统中的用户审计方法。 该方法可以包括部署移动消息系统以与通信耦合的电子邮件服务器配合使用,通过移动消息系统将电子邮件从电子邮件服务器推送到属于不同用户的无线设备,对用户进行计数和比较 当移动消息系统的许可用户的许可数量的许多订户,并且当所计数的用户数量跨过小于许可用户的阈值时,提醒移动消息系统的管理员。 在该实施例的一个方面中,阈值可以为零,因此仅当所计数的用户数量超过许可用户的允许数量时才发送警报。
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公开(公告)号:US20080176762A1
公开(公告)日:2008-07-24
申请号:US12018319
申请日:2008-01-23
CPC分类号: B01J19/0046 , B01J2219/00497 , B01J2219/00549 , B01J2219/00563 , B01J2219/00585 , B01J2219/00655 , B01J2219/00709 , C40B40/00 , C40B50/00 , G01N33/54326 , G01N33/54366 , G06K19/06187
摘要: Microdevices containing a predetermined preferential axis of magnetization are disposed in an array having discreet regions. Under influence of a magnetic field, the microdevices can have at least twelve discrete orientations, and can advantageously be flipped upside down in place. Microdevices can be coded in a manner that supports a coding space of at least 102, 103, 106 or even 1010 or more choices, and can include one or more chemically reactive sites. The regions can be defined by long and short bars, in which microdevices span gaps between the longer bars, and the shorter bars measure less than 60% of such gaps. Preferred embodiments are also provided to produce microfabricated microdevices for magnetic assembly-based arraying.
摘要翻译: 包含预定的磁化优选轴的微器件设置在具有谨慎区域的阵列中。 在磁场的影响下,微器件可以具有至少十二个离散取向,并且可以有利地在适当位置上翻翻。 可以以支持至少10个,10个,10个,6个,甚至10个以上的编码空间的方式对微器件进行编码。 10个或更多个选择,并且可以包括一个或多个化学反应位点。 这些区域可以由长条和短条定义,其中微型设备跨越长条之间的间隙,较短的条测量小于这种间隙的60%。 还提供了优选实施例以产生用于基于磁性组件的排列的微加工微型器件。
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公开(公告)号:US20080081622A1
公开(公告)日:2008-04-03
申请号:US11674738
申请日:2007-02-14
申请人: Jayasri Gunaratnam , Noushad Naqvi , Bryan Taylor , Craig Swann , Hugh Hind , Bao Nguyen , Darcy Phipps
发明人: Jayasri Gunaratnam , Noushad Naqvi , Bryan Taylor , Craig Swann , Hugh Hind , Bao Nguyen , Darcy Phipps
IPC分类号: H04Q7/20
摘要: Reject code handling is utilized for a more time-efficient selection of data-capable networks. One illustrative method for use in selecting a wireless communication network for communications involves the steps of causing a request for data connectivity to be transmitted through a first wireless network; reattempting the request for data connectivity through the first wireless network one or more times if a reject code comprising a non-critical error is received in response to the request for data connectivity through the first wireless network; and attempting to select a second wireless network for communications without reattempting the request for data connectivity through the first wireless network one or more times if a reject code comprising a critical error is received in response to the request for data connectivity through the first wireless network.
摘要翻译: 拒绝代码处理用于更有效地选择具有数据能力的网络。 用于选择用于通信的无线通信网络的一种说明性方法包括以下步骤:通过第一无线网络发送对数据连接的请求; 如果响应于通过第一无线网络的数据连接的请求而接收到包括非关键错误的拒绝代码,则重新尝试通过第一无线网络进行数据连接的请求; 以及如果响应于通过所述第一无线网络的数据连接的请求而接收到包括关键错误的拒绝代码,则尝试选择用于通信的第二无线网络而不重新尝试通过所述第一无线网络进行数据连接的请求。
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公开(公告)号:US20070099475A1
公开(公告)日:2007-05-03
申请号:US11476409
申请日:2006-06-27
申请人: Chinh Le , Bao Nguyen , Tam Nguyen
发明人: Chinh Le , Bao Nguyen , Tam Nguyen
IPC分类号: H01R13/64
CPC分类号: G06F1/185 , H01R12/7047
摘要: A PCI card comprises upper and lower surfaces; a mounting hole defining first and second holes, the first hole having a larger diameter than the second hole; a stud that is inserted into the mounting hole and flushed to the upper surface; and a port connector provided on the stud to minimize space consumption. The first and second holes are concentric circles. Alternatively, the first and second holes are not perfect circles.
摘要翻译: PCI卡包括上表面和下表面; 限定第一孔和第二孔的安装孔,所述第一孔具有比所述第二孔更大的直径; 插入安装孔并冲洗到上表面的螺柱; 以及设置在螺柱上的端口连接器以最小化空间消耗。 第一和第二孔是同心圆。 或者,第一和第二孔不是正圆。
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公开(公告)号:US20060127837A1
公开(公告)日:2006-06-15
申请号:US11301471
申请日:2005-12-12
申请人: Bao Nguyen , Liet Nguyen
发明人: Bao Nguyen , Liet Nguyen
IPC分类号: A61C3/00
CPC分类号: A61C19/063 , A61C19/066 , A61N1/30
摘要: An embodiment of the present invention is a technique for dental bleaching. A tray covers teeth of a user and has a reservoir. A conductor is placed inside the tray. The conductor is covered by a bleaching agent when the bleaching agent fills the reservoir. The conductor is electrically connected to a negative terminal of a power source to cause regeneration of free radicals decomposed from the bleaching agent when power is applied.
摘要翻译: 本发明的一个实施方案是牙科漂白技术。 托盘覆盖使用者的牙齿并具有储存器。 导体放置在托盘内。 当漂白剂填充储存器时,导体被漂白剂覆盖。 导体电连接到电源的负极端子,以在施加电力时引起从漂白剂分解的自由基的再生。
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