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31.发明授权Vascular catheter assembly for tissue penetration and for cardiac stimulation and methods thereof 失效用于组织穿透和用于心脏刺激的血管导管组件及其方法
公开(公告)号：US5330496A
公开(公告)日：1994-07-19
申请号：US695724
申请日：1991-05-06
申请人： Clifton A. Alferness
发明人： Clifton A. Alferness
CPC分类号： A61B5/0422 , A61B17/320016 , A61M25/0105 , A61N1/0587 , A61B2017/00247 , A61B2018/00392 , A61M25/0113
摘要： A vascular catheter apparatus for penetration through tissue and for cardiac stimulation, and a methods thereof, are disclosed. The apparatus includes a tubular member having a lumen, and a blunt-end stylet within the lumen. An actuation mechanism causes axial movement of the stylet relative to the catheter tube such that the blunt end of the stylet separate tissue for passage of the catheter through the bored tissue. The stylet itself, or an additional stylet, includes a proximal electrode adapted to be oriented in a cardiac chamber and a distal electrode adapted to be oriented adjacent to the epicardium of the heart to cause cardiac stimulation.
摘要翻译： 公开了用于穿透组织并用于心脏刺激的血管导管装置及其方法。 该装置包括具有内腔的管状构件和内腔内的平头端管心针。 致动机构导致探针相对于导管的轴向移动，使得探针的钝端分开组织以使导管通过钻孔组织。 探针本身或另外的探针包括适于被定向在心室中的近端电极和适于被定向成邻近心脏心外膜的远端电极以引起心脏刺激。
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公开(公告)号：US5304218A
公开(公告)日：1994-04-19
申请号：US892177
申请日：1992-06-02
申请人： Clifton A. Alferness
发明人： Clifton A. Alferness
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： An arrangement and method facilitates the implantation of an electrode of an endocardial or intravenous lead at an implantation site within the heart of a human. The arrangement includes a guide wire which is formed of flexible material and which may be fed along a predetermined path which includes the implantation site. The arrangement further includes a lead formed of flexible material which includes a proximal end, a distal end, and an electrode to be implanted. The lead further includes an integrally formed follower which slidingly engages the guide wire to permit the lead to be guided along the predetermined path until the electrode to be implanted resides at its implantation site. Thereafter, the guide wire is retracted along the predetermined path to cause the electrode to remain at its implantation site.
摘要翻译： 布置和方法有助于在人的心脏内的植入部位植入心内膜或静脉内引线的电极。 该装置包括由柔性材料形成并且可以沿着包括植入部位的预定路径进给的导丝。 该装置还包括由柔性材料形成的引线，其包括近端，远端和待植入的电极。 引线还包括一体形成的从动件，其滑动地接合导丝，以允许引线沿着预定路径被引导，直到待植入的电极位于其注入位置。 此后，引导线沿着预定路径缩回以使电极保持在其植入位置。
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33.发明授权Atrial defibrillator and method for providing interval timing prior to cardioversion 失效心房除颤器和在心脏复律前提供间隔时间的方法
公开(公告)号：US5207219A
公开(公告)日：1993-05-04
申请号：US965195
申请日：1992-10-23
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/395 , A61N1/3987
摘要： An implantable atrial defibrillator provides cardioverting electrical energy to the atria of a human heart in need of cardioversion. The atrial defibrillator includes a first detector for detecting ventricular activations of the heart, a second detector for detecting atrial activity of the heart, and an atrial fibrillation detector responsive to the second detector for determining when the atria of the heart are in need of cardioversion. The atrial defibrillator also includes a cardioverting stage for applying the cardioverting electrical energy to the atria of the heart when the atria of the heart are in need of cardioversion and when the time between immediately successive ventricular activations is greater than a preselected minimum time interval.
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公开(公告)号：US4066086A
公开(公告)日：1978-01-03
申请号：US722626
申请日：1976-09-13
CPC分类号： A61N1/37217 , A61N1/365 , A61N1/37223
摘要： A body implantable device for providing electrical stimulation to living animal tissue. The device includes a pulse generator having at least one alterable output parameter and circuitry responsive to first externally generated signals for altering the alterable output parameter in predetermined correspondence with the number of said first signals. The output parameter altering circuitry is enabled only during the occurrence of second signals having characteristics discriminable from the characteristics of the first signals. In a preferred embodiment, the first signals are pulses of radio frequency energy and the second signals are magnetic. The invention may be embodied in a cardiac pacemaker of either the asynchronous or demand type and the second signals may be employed to cause a demand cardiac pacemaker to revert to an asynchronous operation.
摘要翻译： 一种用于向活的动物组织提供电刺激的身体可植入装置。 该装置包括具有至少一个可变输出参数的脉冲发生器和响应于第一外部产生的信号的电路，用于以与所述第一信号的数量预定对应的方式改变可变输出参数。 输出参数改变电路仅在具有可与第一信号的特性区分的特性的第二信号的出现期间被使能。 在优选实施例中，第一信号是射频能量的脉冲，第二信号是磁性的。 本发明可以体现在异步或需求类型的心脏起搏器中，并且可以采用第二信号来引起心脏起搏器的需求恢复到异步操作。
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公开(公告)号：US08758308B2
公开(公告)日：2014-06-24
申请号：US11705811
申请日：2007-02-12
IPC分类号： A61M5/31
CPC分类号： A61M5/1452 , A61M5/1408 , A61M5/14248 , A61M5/14526 , A61M5/1454 , A61M5/16881 , A61M2005/1405 , A61M2005/1426 , A61M2005/1585 , A61M2005/1587 , A61M2025/0266
摘要： A disposable infusion device comprises a base arranged to adhere to a patient's skin, a cannula arranged to extend from the base to beneath the patient's skin to deliver a liquid medicament to the patient, and a source arranged to provide the cannula with a liquid medicament. The source includes a compressible tube that pumps the liquid medicament to the cannula.
摘要翻译： 一次性输注装置包括布置成粘附到患者皮肤的基部，布置成从基部延伸到患者皮肤下方以将液体药物递送到患者的插管，以及布置成为套管提供液体药物的源。 源包括将液体药物泵送到套管的可压缩管。
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公开(公告)号：US08753315B2
公开(公告)日：2014-06-17
申请号：US13360485
申请日：2012-01-27
CPC分类号： A61M5/1424 , A61M5/1454 , A61M2005/1405
摘要： A fully manually powered infusion device provides both basal and bolus delivery of a liquid medicament to a patient. In some embodiments, the device includes a main reservoir that supplies the liquid medicament, an outlet port that delivers the liquid medicament to the patient, a basal dispenser that delivers a substantially constant flow of the liquid medicament to the outlet port, and a manually actuated bolus pump that delivers a bolus dose of the liquid medicament from the main reservoir to the outlet when actuated. The basal medicament supply delivers a volume of the liquid medicament from the main reservoir to the basal dispenser consonant with each actuation of the bolus pump.
摘要翻译： 完全手动输液装置提供液体药物到患者的基础和推注。 在一些实施例中，该装置包括供给液体药物的主储存器，将液体药物输送给患者的出口端口，将液体药物的基本上恒定的流量输送到出口的基础分配器，以及手动致动 推动泵，其在致动时将液体药物从主容器输送到出口。 基础药物供应器通过每次推动推注泵将一定体积的液体药物从主储存器输送到基础分配器辅助器。
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37.发明授权Tissue fixation devices and a transoral endoscopic gastroesophageal flap valve restoration device and assembly using same 有权组织固定装置和经口内镜胃食管瓣瓣修复装置及组装使用方法公开(公告)号：US08657837B2
公开(公告)日：2014-02-25
申请号：US12460510
申请日：2009-07-18
IPC分类号： A61B17/08
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/064 , A61B17/068 , A61B2017/00827 , A61B2017/0409 , A61B2017/0414 , A61B2017/0419
摘要： Tissue fasteners carried on a tissue piercing deployment wire fasten tissue layers of a mammalian body together. The fasteners include a first member, a second member, and a connecting member extending between the first and second members. The first and second members are substantially parallel to each other. The fasteners may be deployed in limited spaces and in various applications including the restoration of a gastroesophageal flap valve.
摘要翻译： 携带在组织穿刺部署线上的组织紧固件将哺乳动物身体的组织层紧固在一起。 紧固件包括第一构件，第二构件和在第一构件和第二构件之间延伸的连接构件。 第一和第二构件基本上彼此平行。 紧固件可以在有限的空间和各种应用中部署，包括恢复胃食管瓣阀。
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公开(公告)号：US08277372B2
公开(公告)日：2012-10-02
申请号：US12719553
申请日：2010-03-08
IPC分类号： A61F2/02
CPC分类号： A61F2/2481 , A61F2002/0068
摘要： A cardiac support device comprising a jacket of flexible and biocompatible material having a first axis for alignment generally parallel to a longitudinal axis of a patient's heart and a second axis that is transverse to the first axis. The material exhibits an amount of expansion in response to a force applied to the material along the first axis that is different than an amount of expansion in response to the force applied to the material along the second axis.
摘要翻译： 一种心脏支持装置，其包括柔性和生物相容性材料的护套，其具有大致平行于患者心脏的纵向轴线的对准的第一轴线和横向于第一轴线的第二轴线。 该材料响应于沿着第一轴施加到材料上的力而响应于沿着沿着第二轴施加到材料的力而产生的膨胀量不同的膨胀量。
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公开(公告)号：US20120165856A1
公开(公告)日：2012-06-28
申请号：US13415616
申请日：2012-03-08
申请人： Clifton A. Alferness
发明人： Clifton A. Alferness
IPC分类号： A61M29/00
CPC分类号： A61B17/12104 , A61B17/12022 , A61B17/1204 , A61B17/12159 , A61B17/12172 , A61B2017/1205 , A61B2017/22051 , A61B2017/22067 , A61F2002/043
摘要： An intra-bronchial device may be placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member that prevents air from being inhaled into the lung portion, and an anchor that anchors the obstruction device within the air passageway. The anchor may piercingly engage the air passageway wall. The anchor may be releasable from the air passageway for removal of the obstructing member. The anchor may be releasable by collapsing a portion of the obstructing member, or by drawing the obstructing member toward the larynx. The obstructing member may be a one-way valve.
摘要翻译： 可以将支气管内装置放置并锚定在患者的空气通道中以折叠与空气通道相关联的肺部分。 该装置包括防止空气被吸入肺部的阻塞构件，以及将阻塞装置固定在空气通道内的锚固件。 锚固件可以穿透空气通道壁。 锚固件可以从空气通道释放以去除阻塞构件。 锚固件可以通过塌缩阻塞构件的一部分，或者通过将阻塞构件拉向喉部来释放。 阻塞构件可以是单向阀。
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公开(公告)号：US08177805B2
公开(公告)日：2012-05-15
申请号：US13198546
申请日：2011-08-04
申请人： Clifton A. Alferness
发明人： Clifton A. Alferness
IPC分类号： A61M29/00
CPC分类号： A61B17/12104 , A61B17/12022 , A61B17/1204 , A61B17/12159 , A61B17/12172 , A61B2017/1205 , A61B2017/22051 , A61B2017/22067 , A61F2002/043
摘要： An intra-bronchial device may be placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member that prevents air from being inhaled into the lung portion, and an anchor that anchors the obstruction device within the air passageway. The anchor may piercingly engage the air passageway wall. The anchor may be releasable from the air passageway for removal of the obstructing member. The anchor may be releasable by collapsing a portion of the obstructing member, or by drawing the obstructing member toward the larynx. The obstructing member may be a one-way valve.
摘要翻译： 可以将支气管内装置放置并锚定在患者的空气通道中以折叠与空气通道相关联的肺部分。 该装置包括防止空气被吸入肺部的阻塞构件，以及将阻塞装置固定在空气通道内的锚固件。 锚固件可以穿透空气通道壁。 锚固件可以从空气通道释放以去除阻塞构件。 锚固件可以通过塌缩阻塞构件的一部分，或者通过将阻塞构件拉向喉部来释放。 阻塞构件可以是单向阀。
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