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公开(公告)号：US06656493B2
公开(公告)日：2003-12-02
申请号：US09682164
申请日：2001-07-30
IPC分类号： A61K4736
CPC分类号： A61K8/733 , A61K8/19 , A61K8/73 , A61K8/731 , A61K8/732 , A61K8/97 , A61K9/0056 , A61K9/7007 , A61K2800/594 , A61Q11/00
摘要： Improved edible films for mucoadhesion are provided. The films include at least three types film forming agents other than pullulan, such as maltodextrins, hydrocolloids and fillers. Medicaments and other additive agents can also be incorporated into the edible films. In this regard, the edible films can be utilized to deliver or release the medicaments into an oral cavity, thereby providing effective oral treatment with respect to, for example, oral cleansing and breath freshening.
摘要翻译： 提供改进的用于粘膜粘附的可食用膜。 膜包括除支链淀粉以外的至少三种成膜剂，例如麦芽糖糊精，水胶体和填料。 药剂和其他添加剂也可以并入可食用膜中。 在这方面，可以使用可食用的膜来将药物输送或释放到口腔中，从而为例如口腔清洁和呼吸清新提供有效的口服治疗。
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32.发明授权公开(公告)号：US06350480B1
公开(公告)日：2002-02-26
申请号：US09749983
申请日：2000-12-27
申请人： Philip W. Urnezis , Philip Mazzone , Michael J. Greenberg , Michael T. Bunczek , David G. Barkalow , George W. Monen
发明人： Philip W. Urnezis , Philip Mazzone , Michael J. Greenberg , Michael T. Bunczek , David G. Barkalow , George W. Monen
IPC分类号： A23G330
摘要： A method for producing a chewing gum with an improved release of a lipophilic active agent, as well as the chewing gum so produced, is obtained by using a hydrophilic gum base. The preferred and novel gum base includes hydrophilic polymers, hydrophilic softeners/emulsifiers and fillers, but is essentially free of hydrophobic elastomers and hydrophobic softeners, as well as waxes and elastomer solvents. The lipophilic active agent is preferably added to a coating on a chewing gum pellet made using a hydrophilic gum base, such as by being mixed into a coating solution. The coating solution may contain a high-intensity sweetener. An active agent may also be used in the gum core.
摘要翻译： 通过使用亲水性胶基获得具有改善的亲脂性活性剂的释放以及所生产的口香糖的口香糖的制造方法。 优选和新颖的胶基包括亲水性聚合物，亲水软化剂/乳化剂和填料，但基本上不含疏水性弹性体和疏水软化剂，以及蜡和弹性体溶剂。 优选将亲脂性活性剂加入到使用亲水性胶基制备的口香糖颗粒上的涂层中，例如通过混合到涂布溶液中。 涂层溶液可以含有高强度甜味剂。 胶囊芯中也可以使用活性剂。
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公开(公告)号：US5405623A
公开(公告)日：1995-04-11
申请号：US125296
申请日：1993-09-22
摘要： Methods and compositions for providing improved processability for chewing gum. Pursuant to the present invention, the particle size of the sorbitol component is chosen so that a chewing gum composition is created that is sufficiently firm for processability through a typical chewing gum manufacturing process. To this end, a method is provided for regulating the firmness of a chewing gum composition including sorbitol comprising the step of selecting the particle size distribution of the sorbitol so as to create a chewing gum having desired firmness. By choosing sorbitol with reduced particle sizes, a firm chewing gum is achieved. Likewise, by choosing sorbitol with an increased particle size, a softer chewing gum is achieved.
摘要翻译： 为口香糖提供改善的加工性的方法和组合物。 根据本发明，选择山梨糖醇组分的粒径，使得通过典型的口香糖制造方法产生对于可加工性足够坚固的口香糖组合物。 为此，提供了一种用于调节包含山梨糖醇的口香糖组合物的硬度的方法，该方法包括选择山梨醇的粒度分布以产生具有所需硬度的口香糖的步骤。 通过选择具有减小的粒度的山梨糖醇，实现了稳定的口香糖。 同样，通过选择具有增加的粒度的山梨糖醇，可获得较软的口香糖。
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34.发明授权
公开(公告)号：US5200214A
公开(公告)日：1993-04-06
申请号：US868545
申请日：1992-04-14
摘要： Specific mixtures of tocopherol homologs exhibit surprisingly improved antioxidant effects in mint oil and mint-flavored chewing gum compositions. The mixtures of homologs fall within the range of 7-15% by weight alpha tocopherol, 45-70% by weight gamma tocopherol and 20-35% by weight delta tocopherol. Homologue mixtures within this range are superior to the constituent homologs used alone, and to other homologue mixtures, in terms of antioxidant effects. The compositions of the invention facilitate the replacement of controversial synthetic antioxidants currently used in mint oil and mint-flavored chewing gum, with naturally occurring tocopherols.
摘要翻译： 生育酚同系物的特定混合物在薄荷油和薄荷味口香糖组合物中表现出惊人的改善的抗氧化作用。 同系物的混合物落在7-15重量％的α-生育酚，45-70重量％的γ-生育酚和20-35重量％的δ生育酚的范围内。 在该范围内的同系物混合物优于单独使用的组分同系物，以及抗氧化作用方面优于其他同系物混合物。 本发明的组合物便于将当前用于薄荷油和薄荷味口香糖的有争议的合成抗氧化剂与天然存在的生育酚进行置换。
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