公开(公告)号：US4031090A

公开(公告)日：1977-06-21

申请号：US651942

申请日：1976-01-23

Applicant: David Goldstein ,  William Henry Kibbel, Jr. ,  Roger C. Hollenbach

Inventor： David Goldstein ,  William Henry Kibbel, Jr. ,  Roger C. Hollenbach

IPC: C07D251/34 ,  C07D251/36 ,  C07D251/32

CPC classification number: C07D251/36 ,  C07D251/34

Abstract: Process for preparing a granulated, stabilized alkali metal dichloroisocyanurate by mixing 10-70% of an alkali metal dichloroisocyanurate with 25-75% of cyanuric acid or alkali metal salt thereof, and 5-50% of an inorganic salt, having a pH in water of at least 9, wherein the ingredients are a homogeneous powder and are compacted under pressure, and the compacts crushed to provide a -10 +70 mesh product fraction.

Abstract translation: 通过将10-70％的碱金属二氯异氰脲酸酯与25-75％的三聚氰酸或其碱金属盐和5-50％的无机盐混合制备颗粒状稳定的碱金属二氯异氰脲酸酯的方法，其中pH在水中 至少为9，其中所述成分是均匀的粉末并在压力下压实，并且压块被压碎以提供-10 + 70目的产品级分。

公开(公告)号：US20170325498A1

公开(公告)日：2017-11-16

申请号：US15664575

申请日：2017-07-31

Applicant: David Goldstein

Inventor： David Goldstein

IPC: A24D3/16 ,  A24F1/32 ,  A24F1/02

CPC classification number: A24D3/16 ,  A24F1/02 ,  A24F1/30 ,  A24F1/32 ,  A24F9/00 ,  B01D39/201 ,  B01D41/00 ,  B01D46/10 ,  B01D47/021 ,  B01D50/004 ,  B01D53/14 ,  B01D53/18 ,  B01D2221/10 ,  G01N2001/4066

Abstract: The present invention relates to an improved water pipe comprising a chamber containing water in its lower portion, its upper compact cylindrical portion serving as a smoke collection reservoir; a bowl for combusting tobacco or medicinal herbs, the smoke directed through a tube to the water chamber below the water; and a mouth piece for applying suction to the interior of the chamber to inhale the smoke.

公开(公告)号：US09352260B2

公开(公告)日：2016-05-31

申请号：US13903209

申请日：2013-05-28

Applicant: David Goldstein

Inventor： David Goldstein

IPC: A24F5/00 ,  B01D46/00 ,  B01D46/10 ,  B01D53/14 ,  B01D47/02 ,  B01D50/00 ,  B01L5/04 ,  A24F1/30 ,  A24F9/00 ,  G01N1/40

CPC classification number: B01D46/0023 ,  A24F1/30 ,  A24F9/00 ,  B01D46/10 ,  B01D47/021 ,  B01D50/004 ,  B01D50/006 ,  B01D53/14 ,  B01D2221/10 ,  B01L5/04 ,  B01L2300/0681 ,  B01L2400/049 ,  G01N2001/4066

Abstract: The present invention relates to a glass laboratory apparatus that eliminates a pre filter and a provides a simpler vaporizing platform in fluid communication with a fitted disc filter arranged in an exhaust chamber to scrub solids from a gas using water filtration. A preferred embodiment of the present invention includes a main vessel adapted to hold a volume of a liquid such as water and an inlet conduit with an opening above the liquid level in the main vessel. The inlet conduit includes a vaporizing platform with a platform having four ventilated regions surrounding the platform.

Abstract translation: 本发明涉及一种消除预过滤器的玻璃实验室设备，并且提供了一种与布置在排气室中的装配盘式过滤器流体连通的简单蒸发平台，以使用水过滤从气体中洗涤固体。 本发明的优选实施例包括主容器，其适于容纳一定体积的液体，例如水和具有在主容器中的液面上方的开口的入口导管。 入口管道包括具有平台的蒸发平台，该平台具有围绕平台的四个通风区域。

公开(公告)号：US20150122270A1

公开(公告)日：2015-05-07

申请号：US14594302

申请日：2015-01-12

Applicant: David Goldstein

Inventor： David Goldstein

IPC: B01D46/00 ,  A24F9/00 ,  A24F1/30 ,  B01D47/02 ,  B01D50/00

CPC classification number: B01D46/0023 ,  A24F1/30 ,  A24F9/00 ,  B01D46/10 ,  B01D47/021 ,  B01D50/004 ,  B01D50/006 ,  B01D53/14 ,  B01D2221/10 ,  B01L5/04 ,  B01L2300/0681 ,  B01L2400/049 ,  G01N2001/4066

Abstract: The present invention relates to a glass laboratory apparatus that eliminates a pre filter and a provides a simpler vaporizing platform in fluid communication with a fitted disc filter arranged in an exhaust chamber to scrub solids from a gas using water filtration. A preferred embodiment of the present invention includes a main vessel adapted to hold a volume of a liquid such as water and an inlet conduit with an opening above the liquid level in the main vessel. The inlet conduit includes a vaporizing platform with a platform having four ventilated regions surrounding the platform.

Abstract translation: 本发明涉及一种消除预过滤器的玻璃实验室设备，并且提供了一种与布置在排气室中的装配盘式过滤器流体连通的简单蒸发平台，以使用水过滤从气体中洗涤固体。 本发明的优选实施例包括主容器，其适于容纳一定体积的液体，例如水和具有在主容器中的液面上方的开口的入口导管。 入口管道包括具有平台的蒸发平台，该平台具有围绕平台的四个通风区域。

公开(公告)号：US20130156897A1

公开(公告)日：2013-06-20

申请号：US13570508

申请日：2012-08-09

Applicant: David Goldstein

Inventor： David Goldstein

IPC: B65D85/804

CPC classification number: B65D85/8043

Abstract: A beverage filter cartridge for use in a single serve beverage brewing machine, the cartridge including a sleeve with a cup-shaped filter pouch containing a beverage material sealed to the inside thereof proximate to a top end. The top end includes a flange to which a cover is sealed. A bottom cover of the sleeve seals the cartridge and to prevent spoilage of the beverage material by atmospheric oxygen. The cartridge includes a filter bag with a dry beverage material. The inner surface of the sleeve has a series of vertically oriented channels which allow for the brewed beverage to flow out of the sides of the filter hag and down the channels before exiting the cartridge at the bottom. The brewed beverage can flow out of the bottom of the cartridge either via the side of the filter bag through the channels or through the bottom of the filter bag.

Abstract translation: 一种用于单一饮料酿造机器的饮料过滤器滤芯，所述盒包括具有杯形过滤袋的套筒，所述杯状过滤袋包含密封到靠近顶端的内部的饮料材料。 顶端包括一个盖子被密封的凸缘。 套筒的底盖密封盒，并防止大气氧气对饮料材料造成损坏。 墨盒包括带有干饮料的过滤袋。 套筒的内表面具有一系列垂直定向的通道，其允许酿造的饮料在离开底部的料筒之前从过滤器的侧面流出并向下通道。 酿造的饮料可以通过过滤袋的一侧通过通道或通过过滤袋的底部从筒的底部流出。

公开(公告)号：US20120178736A1

公开(公告)日：2012-07-12

申请号：US13427081

申请日：2012-03-22

Applicant: Georgette Castanedo ,  Bryan Chan ,  David Goldstein ,  Rama Kondru ,  Matthew Lucas ,  Wylie Palmer ,  Stephen Price ,  Brian Safina ,  Pascal Pierre Alexandre Savy ,  Eileen Mary Seward ,  Daniel P. Sutherlin ,  Zachary K. Sweeney

Inventor： Georgette Castanedo ,  Bryan Chan ,  David Goldstein ,  Rama Kondru ,  Matthew Lucas ,  Wylie Palmer ,  Stephen Price ,  Brian Safina ,  Pascal Pierre Alexandre Savy ,  Eileen Mary Seward ,  Daniel P. Sutherlin ,  Zachary K. Sweeney

IPC: A61K31/5377 ,  C07D487/04 ,  A61P29/00 ,  A61P37/00 ,  A61P37/06 ,  A61P37/08 ,  A61P1/04 ,  A61P1/00 ,  A61P17/00 ,  A61P11/06 ,  A61P19/04 ,  A61P25/00 ,  A61P7/02 ,  A61P7/00 ,  A61P11/00 ,  A61P17/06 ,  A61P19/02 ,  C07D495/04

CPC classification number: C07D513/04 ,  C07D487/04 ,  C07D491/04 ,  C07D495/04

Abstract: Formula I (Ia and Ib) compounds wherein (i) X1 is N and X2 is S, (ii) X1 is CR7 and X2 is S, (iii) X1 is N and X2 is NR2, or (iv) X1 is CR7 and X2 is 0, including stereoisomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Abstract translation: 式（I）和（Ib）化合物，其中（i）X1为N，X 2为S，（ii）X1为CR7，X2为S，（iii）X1为N，X2为NR2，或（iv）X1为CR7， X 2为0，包括立体异构体，互变异构体，代谢物和药学上可接受的盐，可用于抑制PI3K的δ同种型，以及用于治疗由脂质激酶如炎症，免疫学和癌症介导的病症。 公开了使用式I化合物在体外，原位和体内诊断，预防或治疗哺乳动物细胞或相关病理状况中的这种病症的方法。

公开(公告)号：US08025505B2

公开(公告)日：2011-09-27

申请号：US12343351

申请日：2008-12-23

Applicant: Michael C. Wood ,  Alice Chen Jordan ,  David Goldstein ,  Mark Flowers ,  Joseph B. Miller, III ,  Michelle Fitts ,  Curtis Cole ,  Rick Adolf ,  Antonia Kohl ,  Carol Thies

Inventor： Michael C. Wood ,  Alice Chen Jordan ,  David Goldstein ,  Mark Flowers ,  Joseph B. Miller, III ,  Michelle Fitts ,  Curtis Cole ,  Rick Adolf ,  Antonia Kohl ,  Carol Thies

IPC: G09B7/00

CPC classification number: A63F13/92 ,  A63F13/08 ,  A63F13/2145 ,  A63F13/95 ,  A63F2300/1075 ,  A63F2300/204 ,  A63F2300/206 ,  A63F2300/302 ,  G09B5/06 ,  G09B19/00 ,  H01M2/1022

Abstract: An interactive, handheld apparatus is provided. The apparatus includes a housing, a display screen on the housing, an electronic position location system, a stylus for selecting images on the display screen, a directional control pad on the housing and a memory device. The electronic position location system includes a processor that is capable of determining a location of a selected region of the display screen. The memory device includes computer code for an educational game and is operatively coupled to the processor.

Abstract translation: 提供了一种交互式手持设备。 该装置包括壳体，壳体上的显示屏，电子位置定位系统，用于在显示屏幕上选择图像的触控笔，壳体上的方向控制板和存储器件。 电子位置定位系统包括能够确定显示屏幕的选定区域的位置的处理器。 存储装置包括用于教育游戏的计算机代码，并且可操作地耦合到处理器。

公开(公告)号：US07553160B2

公开(公告)日：2009-06-30

申请号：US11404961

申请日：2006-04-13

Applicant: Michael C. Wood ,  Alice Chen ,  David Goldstein ,  Mark Flowers ,  Joseph B. Miller, III ,  Michelle Fitts ,  Curtis Cole ,  Rick Adolf ,  Antonia Kohl ,  Carol Thies

Inventor： Michael C. Wood ,  Alice Chen ,  David Goldstein ,  Mark Flowers ,  Joseph B. Miller, III ,  Michelle Fitts ,  Curtis Cole ,  Rick Adolf ,  Antonia Kohl ,  Carol Thies

IPC: G09B7/00

CPC classification number: A63F13/92 ,  A63F13/08 ,  A63F13/2145 ,  A63F13/95 ,  A63F2300/1075 ,  A63F2300/204 ,  A63F2300/206 ,  A63F2300/302 ,  G09B5/06 ,  G09B19/00 ,  H01M2/1022

Abstract: An interactive, handheld apparatus is provided. The apparatus includes a housing, a display screen on the housing, an electronic position location system, a stylus for selecting images on the display screen, a directional control pad on the housing and a memory device. The electronic position location system includes a processor that is capable of determining a location of a selected region of the display screen. The memory device includes computer code for an educational game and is operatively coupled to the processor.

Abstract translation: 提供了一种交互式手持设备。 该装置包括壳体，壳体上的显示屏，电子位置定位系统，用于在显示屏幕上选择图像的触控笔，壳体上的方向控制板和存储器件。 电子位置定位系统包括能够确定显示屏幕的选定区域的位置的处理器。 存储装置包括用于教育游戏的计算机代码，并且可操作地耦合到处理器。

公开(公告)号：US07529519B2

公开(公告)日：2009-05-05

申请号：US10776012

申请日：2004-02-09

Applicant: Michael C. Wood ,  Alice Chen Jordan ,  David Goldstein ,  Mark Flowers ,  Joseph B. Miller, III ,  Michelle Fitts ,  Robert Curtis Cole ,  Rick Adolf ,  Antonia Kohl ,  Carol Thies

Inventor： Michael C. Wood ,  Alice Chen Jordan ,  David Goldstein ,  Mark Flowers ,  Joseph B. Miller, III ,  Michelle Fitts ,  Robert Curtis Cole ,  Rick Adolf ,  Antonia Kohl ,  Carol Thies

IPC: G09B5/00

CPC classification number: A63F13/92 ,  A63F13/08 ,  A63F13/2145 ,  A63F13/95 ,  A63F2300/1075 ,  A63F2300/204 ,  A63F2300/206 ,  A63F2300/302 ,  G09B5/06 ,  G09B19/00 ,  H01M2/1022

Abstract: An interactive, handheld apparatus is provided. The apparatus includes a housing, a display screen on the housing, an electronic position location system, a stylus for selecting images on the display screen, a directional control pad on the housing and a memory device. The electronic position location system includes a processor that is capable of determining a location of a selected region of the display screen. The memory device includes computer code for an educational game and is operatively coupled to the processor. A light is associated with the stylus. The light is illuminated to indicate that the stylus is available for use during operation of the educational game.

Abstract translation: 提供了一种交互式手持设备。 该装置包括壳体，壳体上的显示屏，电子位置定位系统，用于在显示屏幕上选择图像的触控笔，壳体上的方向控制板和存储器件。 电子位置定位系统包括能够确定显示屏幕的选定区域的位置的处理器。 存储装置包括用于教育游戏的计算机代码，并且可操作地耦合到处理器。 灯与触控笔相关联。 指示灯亮起，表示在教育游戏操作期间可以使用手写笔。

公开(公告)号：US20050197352A1

公开(公告)日：2005-09-08

申请号：US11122137

申请日：2005-05-04

Applicant: David Goldstein ,  Ronald Hawley ,  Alfred Lui ,  Eric Sjogren

Inventor： David Goldstein ,  Ronald Hawley ,  Alfred Lui ,  Eric Sjogren

IPC: A61P11/00 ,  A61P25/00 ,  A61P29/00 ,  C07D471/14 ,  C07D487/14 ,  A61K31/519

CPC classification number: C07D471/14 ,  C07D487/14

Abstract: The present invention discloses compounds corresponding to formula I: wherein A, Z, Z1, Y, R1 and R2 are as defined in the specification, as well as pharmaceutical formulations, methods of making and uses thereof.