公开(公告)号：US20150366494A1

公开(公告)日：2015-12-24

申请号：US14841368

申请日：2015-08-31

Applicant: DexCom, Inc.

Inventor： Jonathan Hughes ,  Robert J. Boock ,  Chris W. Dring ,  Huashi Zhang ,  Mark Wu ,  David Sze

IPC: A61B5/1486 ,  A61B5/145

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/14546

Abstract: Devices are presented for measurement of an analyte concentration. The devices comprise: a sensor configured to generate a signal indicative of a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme domain comprising an enzyme, a base polymer, and a hydrophilic polymer which makes up from about 5 wt. % to about 30 wt. % of the enzyme domain.

Abstract translation: 用于测量分析物浓度的装置。 所述装置包括：传感器，被配置为产生指示分析物浓度的信号; 以及位于传感器上方的感测膜。 感测膜包括酶结构域，其包含酶，基础聚合物和亲水性聚合物，其由约5wt。 ％至约30wt。 ％的酶结构域。

公开(公告)号：US20250025071A1

公开(公告)日：2025-01-23

申请号：US18910279

申请日：2024-10-09

Applicant: Dexcom, Inc.

Inventor： Naresh C. Bhavaraju ,  Michael A. Bloom ,  Leif N. Bowman ,  Alexandra Lynn Carlton ,  Katherine Yerre Koehler ,  Hari Hampapuram ,  Lauren Hruby Jepson ,  Jonathan Hughes ,  Apurv Ullas Kamath ,  Anna Leigh Davis ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1455 ,  A61B5/1486 ,  A61B5/1495 ,  A61M5/172 ,  G16H40/40 ,  G16H40/63

Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

公开(公告)号：US11656195B2

公开(公告)日：2023-05-23

申请号：US16402101

申请日：2019-05-02

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Becky L. Clark ,  Vincent P. Crabtree ,  Chris W. Dring ,  Arturo Garcia ,  Jason Halac ,  Jonathan Hughes ,  Jeff Jackson ,  Lauren Hruby Jepson ,  David I-Chun Lee ,  Ted Tang Lee ,  Rui Ma ,  Zebediah L. McDaniel ,  Jason Mitchell ,  Andrew Attila Pal ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Stephen J. Vanslyke ,  Matthew D. Wightlin ,  Anna Leigh Davis ,  Hari Hampapuram ,  Aditya Sagar Mandapaka ,  Alexander Leroy Teeter ,  Liang Wang

IPC: G01N27/327 ,  A61B5/145 ,  A61B5/1495

CPC classification number: G01N27/3274 ,  A61B5/1495 ,  A61B5/14532 ,  A61B2560/0223

Abstract: Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

公开(公告)号：US20230032816A1

公开(公告)日：2023-02-02

申请号：US17962308

申请日：2022-10-07

Applicant: DexCom, Inc.

Inventor： Ryan Everett Schoonmaker ,  Jennifer Blackwell ,  Christopher M. Davis ,  David DeRenzy ,  Eric Gobrecht ,  Jason Halac ,  Jonathan Hughes ,  Kathleen Suzanne Hurst ,  Randall Scott Koplin ,  Phong Lieu ,  Kyle Neuser ,  Todd Andrew Newhouse ,  Jack Pryor ,  Peter C. Simpson ,  Maria Noel Brown Wells ,  Justen Deering England ,  Stefanie Lynn Mah ,  Leonard Darius Barbod ,  Jillian K. Allen ,  Michael J. Estes ,  Philip Thomas Pupa ,  Timothy Joseph Goldsmith ,  Kyle Tinnell Keller

IPC: A61B17/34 ,  A61B5/00 ,  A61B5/145

Abstract: The present embodiments relate generally to systems and methods for measuring an analyte in a host. More particularly, the present embodiments provide sensor applicators and methods of use with activation that implant the sensor, withdraw the insertion needle, engage the transmitter with the housing, and disengage the applicator from the housing. Systems and methods according to present principles allow for such steps to occur without significant loss of spring force, and without deleterious effects such as seal slingshotting.

公开(公告)号：US20210330219A1

公开(公告)日：2021-10-28

申请号：US17368541

申请日：2021-07-06

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  A61B5/145 ,  G01N33/66

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US11051731B2

公开(公告)日：2021-07-06

申请号：US16911172

申请日：2020-06-24

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  A61B5/145 ,  G01N33/66 ,  A61B5/1486

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US10729364B2

公开(公告)日：2020-08-04

申请号：US16407055

申请日：2019-05-08

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  A61B5/145 ,  G01N33/66 ,  A61B5/1486

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US20190339223A1

公开(公告)日：2019-11-07

申请号：US16402116

申请日：2019-05-02

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Becky L. Clark ,  Vincent P. Crabtree ,  Chris W. Dring ,  Arturo Garcia ,  Jason Halac ,  Jonathan Hughes ,  Jeff Jackson ,  Lauren Hruby Jepson ,  David I-Chun Lee ,  Ted Tang Lee ,  Rui Ma ,  Zebediah L. McDaniel ,  Jason Mitchell ,  Andrew Attila Pal ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Stephen J. Vanslyke ,  Matthew D. Wightlin ,  Anna Leigh Davis ,  Hari Hampapuram ,  Aditya Sagar Mandapaka ,  Alexander Leroy Teeter ,  Liang Wang

IPC: G01N27/327

Abstract: Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

公开(公告)号：US20190339222A1

公开(公告)日：2019-11-07

申请号：US16402101

申请日：2019-05-02

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Becky L. Clark ,  Vincent P. Crabtree ,  Chris W. Dring ,  Arturo Garcia ,  Jason Halac ,  Jonathan Hughes ,  Jeff Jackson ,  Lauren Hruby Jepson ,  David I-Chun Lee ,  Ted Tang Lee ,  Rui Ma ,  Zebediah L. McDaniel ,  Jason Mitchell ,  Andrew Attila Pal ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Stephen J. Vanslyke ,  Matthew D. Wightlin ,  Anna Leigh Davis ,  Hari Hampapuram ,  Aditya Sagar Mandapaka ,  Alexander Leroy Teeter ,  Liang Wang

IPC: G01N27/327

Abstract: Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

公开(公告)号：US20190328292A1

公开(公告)日：2019-10-31

申请号：US16504179

申请日：2019-07-05

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Michael A. Bloom ,  Leif N. Bowman ,  Alexandra Lynn Carlton ,  Katherine Yerre Koehler ,  Hari Hampapuram ,  Jonathan Hughes ,  Lauren Hruby Jepson ,  Apurv Ullas Kamath ,  Anna Leigh Rack-Gomer ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/145 ,  A61B5/00 ,  G16H40/63 ,  A61M5/172 ,  A61B5/1486 ,  A61B5/1455 ,  G16H40/40 ,  A61B5/1495

Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.