公开(公告)号：US11974845B2

公开(公告)日：2024-05-07

申请号：US17368541

申请日：2021-07-06

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  A61B5/145 ,  G01N33/66 ,  A61B5/1486

CPC classification number: A61B5/1495 ,  A61B5/14532 ,  G01N33/66 ,  A61B5/14865

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US20230284944A1

公开(公告)日：2023-09-14

申请号：US18198085

申请日：2023-05-16

Applicant: Dexcom, Inc.

Inventor： Shanger Wang ,  Devon M. Headen ,  Sebastian Bohm ,  Jonathan Hughes ,  Ted Tang Lee ,  Peter C. Simpson ,  Jiong Zou

IPC: A61B5/1486 ,  A61B5/00 ,  C12Q1/00 ,  A61B5/145 ,  C12Q1/54

CPC classification number: A61B5/14865 ,  A61B5/0022 ,  C12Q1/006 ,  C12Q1/002 ,  A61B5/14532 ,  A61B5/14546 ,  C12Q1/54 ,  G01N27/3271

Abstract: Flexible analyte sensors are provided. Flexible analyte sensors may be flexible continuous analyte sensors that facilitate continuous monitoring of an analyte such as blood glucose. The flexible analyte sensor may have a relatively flexible conductive or non-conductive core, may be formed from a plurality of substantially planar layers, or may be configured to transform from a freestanding sensor ex vivo to a non-freestanding sensor in vivo.

公开(公告)号：US11219413B2

公开(公告)日：2022-01-11

申请号：US14835603

申请日：2015-08-25

Applicant: DexCom, Inc.

Inventor： James Jinwoo Lee ,  Leif N. Bowman ,  Tim Ray Gackstetter ,  Jonathan Hughes ,  Jeff Jackson ,  Ted Tang Lee ,  Phong Lieu ,  Andrew Attila Pal ,  James R. Petisce ,  Jack Pryor ,  Roger Schneider ,  Peter C. Simpson ,  George Vigil ,  Matthew D. Wightlin

IPC: A61B5/00 ,  A61B5/145

Abstract: Adhesive pad systems that provide longer lasting adherence of the mounting unit to the host's skin are provided. Some systems include a reinforcing overlay that at least partially covers the adhesive pad. The reinforcing overlay may be removable without disturbing the sensor so that the overlay may be replaceable.

公开(公告)号：US20200170671A1

公开(公告)日：2020-06-04

申请号：US16784198

申请日：2020-02-06

Applicant: DexCom, Inc.

Inventor： Ryan Everett Schoonmaker ,  Jennifer Blackwell ,  Christopher M. Davis ,  David DeRenzy ,  Eric Gobrecht ,  Jason Halac ,  Jonathan Hughes ,  Kathleen Suzanne Hurst ,  Randall Scott Koplin ,  Phong Lieu ,  Kyle Neuser ,  Todd Andrew Newhouse ,  Jack Pryor ,  Peter C. Simpson ,  Maria Noel Brown Wells ,  Justen Deering England ,  Stefanie Lynn Mah ,  Leonard Darius Barbod ,  Jillian K. Allen ,  Michael J. Estes ,  Philip Thomas Pupa ,  Timothy Joseph Goldsmith ,  Kyle Tinnell Keller

IPC: A61B17/34 ,  A61B5/00 ,  A61B5/145

Abstract: The present embodiments relate generally to systems and methods for measuring an analyte in a host. More particularly, the present embodiments provide sensor applicators and methods of use with activation that implant the sensor, withdraw the insertion needle, engage the transmitter with the housing, and disengage the applicator from the housing. Systems and methods according to present principles allow for such steps to occur without significant loss of spring force, and without deleterious effects such as seal slingshotting.

公开(公告)号：US10413227B2

公开(公告)日：2019-09-17

申请号：US15652663

申请日：2017-07-18

Applicant: DexCom, Inc.

Inventor： Jonathan Hughes ,  Robert J. Boock ,  Chris W. Dring ,  Huashi Zhang ,  Mark Wu ,  David Sze

IPC: A61B5/1486 ,  A61B5/145

Abstract: Devices are presented for measurement of an analyte concentration. The devices comprise: a sensor configured to generate a signal indicative of a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme domain comprising an enzyme, a base polymer, and a hydrophilic polymer which makes up from about 5 wt. % to about 30 wt. % of the enzyme domain.

公开(公告)号：US10362975B2

公开(公告)日：2019-07-30

申请号：US15394327

申请日：2016-12-29

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  G01N33/66 ,  A61B5/145 ,  A61B5/1486

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US20180199873A1

公开(公告)日：2018-07-19

申请号：US15874503

申请日：2018-01-18

Applicant: DexCom, Inc.

Inventor： Shanger Wang ,  Devon M. Headen ,  Sebastian Bohm ,  Jonathan Hughes ,  Ted Tang Lee ,  Peter C. Simpson ,  Jiong Zou

IPC: A61B5/1486 ,  G01N27/327 ,  A61B5/00 ,  C12Q1/00 ,  C12Q1/54

CPC classification number: A61B5/14865 ,  A61B5/0022 ,  A61B5/14532 ,  A61B5/14546 ,  A61B2562/125 ,  A61B2562/164 ,  C12Q1/002 ,  C12Q1/006 ,  C12Q1/54 ,  G01N27/3271

Abstract: Flexible analyte sensors are provided. Flexible analyte sensors may be flexible continuous analyte sensors that facilitate continuous monitoring of an analyte such as blood glucose. The flexible analyte sensor may have a relatively flexible conductive or non-conductive core, may be formed from a plurality of substantially planar layers, or may be configured to transform from a freestanding sensor ex vivo to a non-freestanding sensor in vivo.

公开(公告)号：US20170311859A1

公开(公告)日：2017-11-02

申请号：US15652663

申请日：2017-07-18

Applicant: DexCom, Inc.

Inventor： Jonathan Hughes ,  Robert J. Boock ,  Chris W. Dring ,  Huashi Zhang ,  Mark Wu ,  David Sze

IPC: A61B5/1486 ,  A61B5/145

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/14546

Abstract: Devices are presented for measurement of an analyte concentration. The devices comprise: a sensor configured to generate a signal indicative of a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme domain comprising an enzyme, a base polymer, and a hydrophilic polymer which makes up from about 5 wt. % to about 30 wt. % of the enzyme domain.

公开(公告)号：US20170188906A1

公开(公告)日：2017-07-06

申请号：US15394327

申请日：2016-12-29

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  G01N33/66 ,  A61B5/145

CPC classification number: A61B5/1495 ,  A61B5/14532 ,  A61B5/14865 ,  G01N33/66

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US12144612B2

公开(公告)日：2024-11-19

申请号：US14975444

申请日：2015-12-18

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Michael A. Bloom ,  Leif N. Bowman ,  Alexandra Lynn Carlton ,  Katherine Yerre Koehler ,  Hari Hampapuram ,  Lauren Hruby Jepson ,  Jonathan Hughes ,  Apurv Ullas Kamath ,  Anna Leigh Davis ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1455 ,  A61B5/1486 ,  A61B5/1495 ,  A61M5/172 ,  G16H40/40 ,  G16H40/63

Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.