公开(公告)号：US12048540B2

公开(公告)日：2024-07-30

申请号：US16261339

申请日：2019-01-29

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Davis ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/01 ,  A61B5/053 ,  A61B5/11 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  A61M5/172 ,  G16Z99/00

CPC classification number: A61B5/1495 ,  A61B5/01 ,  A61B5/053 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/6898 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  A61M5/1723 ,  G16Z99/00 ,  A61B2560/0247 ,  A61B2560/0252 ,  A61B2560/0276 ,  A61B2560/0475 ,  A61B2562/0247 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/201

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US11974845B2

公开(公告)日：2024-05-07

申请号：US17368541

申请日：2021-07-06

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  A61B5/145 ,  G01N33/66 ,  A61B5/1486

CPC classification number: A61B5/1495 ,  A61B5/14532 ,  G01N33/66 ,  A61B5/14865

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US11837348B2

公开(公告)日：2023-12-05

申请号：US17933197

申请日：2022-09-19

Applicant: Dexcom, Inc.

Inventor： Anna Leigh Davis ,  Scott M. Belliveau ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Rita M. Castillo ,  Alexandra Elena Constantin ,  Rian W. Draeger ,  Laura J. Dunn ,  Gary Brian Gable ,  Arturo Garcia ,  Thomas Hall ,  Hari Hampapuram ,  Christopher Robert Hannemann ,  Anna Claire Harley-Trochimczyk ,  Nathaniel David Heintzman ,  Andrea Jean Jackson ,  Lauren Hruby Jepson ,  Apurv Ullas Kamath ,  Katherine Yerre Koehler ,  Aditya Sagar Mandapaka ,  Samuel Jere Marsh ,  Gary A. Morris ,  Subrai Girish Pai ,  Andrew Attila Pal ,  Nicholas Polytaridis ,  Philip Thomas Pupa ,  Eli Reihman ,  Ashley Anne Rindfleisch ,  Sofie Wells Schunk ,  Peter C. Simpson ,  Daniel S. Smith ,  Stephen J. Vanslyke ,  Matthew T. Vogel ,  Tomas C. Walker ,  Benjamin Elrod West ,  Atiim Joseph Wiley

IPC: G16H20/17 ,  G16H50/20 ,  G06N20/00 ,  A61B5/00 ,  H04M1/72412 ,  A61B5/024 ,  A61B5/11 ,  A61B5/145 ,  A61B5/16 ,  G08B21/04 ,  G06N5/043 ,  A61M5/172 ,  G16H40/67 ,  G16H40/63

CPC classification number: G16H20/17 ,  A61B5/0022 ,  A61B5/024 ,  A61B5/1112 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/165 ,  A61B5/4866 ,  A61B5/742 ,  A61B5/746 ,  A61M5/1723 ,  G06N5/043 ,  G06N20/00 ,  G08B21/0453 ,  G16H40/63 ,  G16H40/67 ,  G16H50/20 ,  H04M1/72412 ,  A61M2205/18 ,  A61M2205/3584 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/8206 ,  A61M2230/201 ,  Y02A90/10

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

公开(公告)号：US20230140651A1

公开(公告)日：2023-05-04

申请号：US18049924

申请日：2022-10-26

Applicant: Dexcom. Inc.

Inventor： Arturo Garcia ,  Peter C. Simpson ,  Apurv U. Kamath ,  Naresh C. Bhavaraju ,  Stephen J. Vanslyke

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1495

Abstract: Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.

公开(公告)号：US11450421B2

公开(公告)日：2022-09-20

申请号：US16904454

申请日：2020-06-17

Applicant: DexCom, Inc.

Inventor： Anna Leigh Davis ,  Scott M. Belliveau ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Rita M. Castillo ,  Alexandra Elena Constantin ,  Rian Draeger ,  Laura J. Dunn ,  Gary Brian Gable ,  Arturo Garcia ,  Thomas Hall ,  Hari Hampapuram ,  Christopher Robert Hannemann ,  Anna Claire Harley-Trochimczyk ,  Nathaniel David Heintzman ,  Andrea Jean Jackson ,  Lauren Hruby Jepson ,  Apurv Ullas Kamath ,  Katherine Yerre Koehler ,  Aditya Sagar Mandapaka ,  Samuel Jere Marsh ,  Gary A. Morris ,  Subrai Girish Pai ,  Andrew Attila Pal ,  Nicholas Polytaridis ,  Philip Thomas Pupa ,  Eli Reihman ,  Ashley Anne Rindfleisch ,  Sofie Wells Schunk ,  Peter C. Simpson ,  Daniel Smith ,  Stephen J. Vanslyke ,  Matthew T. Vogel ,  Tomas C. Walker ,  Benjamin Elrod West ,  Atiim Joseph Wiley

IPC: G16H20/17 ,  G16H50/20 ,  G06N20/00 ,  A61B5/00 ,  H04M1/72412 ,  A61B5/024 ,  A61B5/11 ,  A61B5/145 ,  A61B5/16 ,  G08B21/04 ,  G06N5/04 ,  A61M5/172 ,  G16H40/67 ,  G16H40/63

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

公开(公告)号：US10737025B2

公开(公告)日：2020-08-11

申请号：US15684361

申请日：2017-08-23

Applicant: DexCom, Inc.

Inventor： Anna Leigh Davis ,  Scott M. Belliveau ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Rita M. Castillo ,  Alexandra Elena Constantin ,  Rian Draeger ,  Laura J. Dunn ,  Gary Brian Gable ,  Arturo Garcia ,  Thomas Hall ,  Hari Hampapuram ,  Christopher Robert Hannemann ,  Anna Claire Harley-Trochimczyk ,  Nathaniel David Heintzman ,  Andrea J. Jackson ,  Lauren Hruby Jepson ,  Apurv Ullas Kamath ,  Katherine Yerre Koehler ,  Aditya Sagar Mandapaka ,  Samuel Jere Marsh ,  Gary A. Morris ,  Subrai Girish Pai ,  Andrew Attila Pal ,  Nicholas Polytaridis ,  Philip Thomas Pupa ,  Eli Reihman ,  Ashley Anne Rindfleisch ,  Sofie Wells Schunk ,  Peter C. Simpson ,  Daniel Smith ,  Stephen J. Vanslyke ,  Matthew T. Vogel ,  Tomas C. Walker ,  Benjamin Elrod West ,  Atiim Joseph Wiley

IPC: A61M5/172 ,  G16H50/20 ,  G06N20/00 ,  A61B5/00 ,  A61B5/024 ,  A61B5/11 ,  A61B5/145 ,  A61B5/16 ,  G06F19/00 ,  G08B21/04 ,  H04M1/725 ,  G06N5/04 ,  G16H20/17 ,  G16H40/67 ,  G16H40/63

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

公开(公告)号：US20200205705A1

公开(公告)日：2020-07-02

申请号：US16728945

申请日：2019-12-27

Applicant: DexCom, Inc.

Inventor： Ted Tang Lee ,  Anna Leigh Davis ,  Peter C. Simpson ,  Liang Wang ,  Shanger Wang ,  Jiong Zou ,  Stephen J. Vanslyke ,  Rui Ma ,  Wenjie Lan

IPC: A61B5/145 ,  A61B5/1495 ,  A61B5/1473

Abstract: Various examples described herein are directed to systems, apparatuses, and methods for mitigating break-in in an analyte sensor. An example analyte sensor system comprises an analyte sensor applicator comprising a needle; an analyte sensor comprising at least a working electrode and a reference electrode, the analyte sensor positioned at least partially within a lumen of the needle; and a hydrating agent positioned within the lumen of the needle to at least partially hydrate the needle.

公开(公告)号：US10470661B2

公开(公告)日：2019-11-12

申请号：US15261816

申请日：2016-09-09

Applicant: DexCom, Inc.

Inventor： Arturo Garcia ,  Peter C. Simpson ,  Apurv Ullas Kamath ,  Naresh C. Bhavaraju ,  Stephen J. Vanslyke

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1495 ,  A61B5/11

Abstract: Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.

公开(公告)号：US10470660B2

公开(公告)日：2019-11-12

申请号：US15261711

申请日：2016-09-09

Applicant: DexCom, Inc.

Inventor： Arturo Garcia ,  Peter C. Simpson ,  Apurv Ullas Kamath ,  Naresh C. Bhavaraju ,  Stephen J. Vanslyke

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1495 ,  A61B5/11

Abstract: Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.

公开(公告)号：US20190261905A1

公开(公告)日：2019-08-29

申请号：US16412274

申请日：2019-05-14

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Lucas Bohnett ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Jack Pryor

IPC: A61B5/1495 ,  G16H40/40

Abstract: Systems and methods for processing sensor data and calibration of the sensors are provided. In some embodiments, the method for calibrating at least one sensor data point from an analyte sensor comprises receiving a priori calibration distribution information; receiving one or more real-time inputs that may influence calibration of the analyte sensor; forming a posteriori calibration distribution information based on the one or more real-time inputs; and converting, in real-time, at least one sensor data point calibrated sensor data based on the a posteriori calibration distribution information.