公开(公告)号：US20230219888A1

公开(公告)日：2023-07-13

申请号：US17955922

申请日：2022-09-29

Applicant: ENVERIC BIOSCIENCES CANADA INC.

Inventor： Jillian M. Hagel ,  Peter J. Facchini ,  Xue Chen

IPC: C07D209/16

CPC classification number: C07D209/16

Abstract: Disclosed are novel prenylated psilocybin derivative compounds and pharmaceutical and recreational drug formulations containing the same. The compounds may be produced in vitro or in vivo using a biosynthetic system which comprises cells comprising a prenyl transferase, and, optionally, additional enzymes, including a decarboxylase, and an N-acetyl transferase.

公开(公告)号：US20230051548A1

公开(公告)日：2023-02-16

申请号：US17946508

申请日：2022-09-16

Applicant: Enveric Biosciences Canada Inc.

Inventor： Jillian M. Hagel ,  Peter J. Facchini ,  Chang-Chun Ling

IPC: A61K31/4045 ,  C07D209/16 ,  C12N15/52 ,  C12P17/10 ,  A61P25/00 ,  C12N9/10 ,  C12N9/88

Abstract: Disclosed are novel nitrilated psilocybin derivative compounds and pharmaceutical and recreational drug formulations containing the same. The compounds may be produced by reacting a reactant psilocybin derivative with a nitrile-group containing compound.

公开(公告)号：US20230040398A1

公开(公告)日：2023-02-09

申请号：US17941531

申请日：2022-09-09

Applicant: Enveric Biosciences Canada Inc.

Inventor： Jillian M. Hagel ,  Peter J. Facchini ,  Chang-Chun Ling

IPC: A61K31/4045 ,  A61P25/18

Abstract: Disclosed are novel nitrated psilocybin derivative compounds and pharmaceutical and recreational drug formulations containing the same. The nitrated psilocybin derivative compounds may be chemically synthesized or biochemically synthesized in host cells.

公开(公告)号：US12195439B1

公开(公告)日：2025-01-14

申请号：US18494382

申请日：2023-10-25

Applicant: Enveric Biosciences Canada Inc.

Inventor： Kaveh Matinkhoo ,  David James Press ,  Glynnis Elizabeth Jensen ,  Jillian M. Hagel ,  Peter J. Facchini

IPC: C07D317/58 ,  A61P25/00 ,  C07D319/18 ,  C07D405/06

Abstract: Disclosed are novel fused mescaline derivative compounds, notably C1-substituted isopropylamine fused heterocyclic mescaline derivatives, including C1-substituted isopropylamine fused dioxolane and fused dioxane mescaline derivatives, and pharmaceutical and recreational drug formulations containing the same. Methods of making and using these compounds are also disclosed.

公开(公告)号：US20240299427A1

公开(公告)日：2024-09-12

申请号：US18655793

申请日：2024-05-06

Applicant: Enveric Biosciences Canada Inc.

Inventor： Jillian M. Hagel ,  Peter J. Facchini

IPC: A61K31/675 ,  A61K31/4045 ,  C12N9/02 ,  C12N9/10 ,  C12N9/12 ,  C12N15/52 ,  C12P17/10

CPC classification number: A61K31/675 ,  A61K31/4045 ,  C12N9/0083 ,  C12N9/1007 ,  C12N9/1205 ,  C12N15/52 ,  C12P17/10

Abstract: Disclosed are novel halogenated psilocybin derivative compounds and pharmaceutical and recreational drug formulations containing the same. The compounds may be produced using a biosynthetic system which comprises cells comprising a psilocybin biosynthetic enzyme complement.

公开(公告)号：US20240173340A1

公开(公告)日：2024-05-30

申请号：US18390228

申请日：2023-12-20

Applicant: Enveric Biosciences Canada Inc.

Inventor： Jillian M. Hagel ,  Peter J. Facchini ,  Chang-Chun Ling

IPC: A61K31/675 ,  A61P25/18

CPC classification number: A61K31/675 ,  A61P25/18

Abstract: Disclosed are novel multi-substituent psilocybin derivative compounds and pharmaceutical and recreational drug formulations containing the same. The compounds may be produced by reacting a reactant psilocybin derivative with a substituent containing compound.

公开(公告)号：US11931338B2

公开(公告)日：2024-03-19

申请号：US17946508

申请日：2022-09-16

Applicant: Enveric Biosciences Canada Inc.

Inventor： Jillian M. Hagel ,  Peter J. Facchini ,  Chang-Chun Ling

IPC: A61K31/4045 ,  A61P25/00 ,  C07D209/16 ,  C12N9/10 ,  C12N9/88 ,  C12N15/52 ,  C12P17/10

CPC classification number: A61K31/4045 ,  A61P25/00 ,  C07D209/16 ,  C12N9/1007 ,  C12N9/1029 ,  C12N9/88 ,  C12N15/52 ,  C12P17/10 ,  C12Y203/01087 ,  C12Y401/01028 ,  C12Y402/0102

Abstract: Disclosed are novel nitrilated psilocybin derivative compounds and pharmaceutical and recreational drug formulations containing the same. The compounds may be produced by reacting a reactant psilocybin derivative with a nitrile-group containing compound.

公开(公告)号：US11891360B2

公开(公告)日：2024-02-06

申请号：US17941425

申请日：2022-09-09

Applicant: Enveric Biosciences Canada Inc.

Inventor： Jillian M. Hagel ,  Peter J. Facchini ,  Chang-Chun Ling

IPC: C07D209/20 ,  C07H17/02

CPC classification number: C07D209/20 ,  C07H17/02

Abstract: Disclosed are novel glycosylated psilocybin derivative compounds and pharmaceutical and recreational drug formulations containing the same. The compounds may be produced by reacting a hydroxylated psilocybin derivative with a glycosyl compound.

公开(公告)号：US11845727B2

公开(公告)日：2023-12-19

申请号：US17951594

申请日：2022-09-23

Applicant: Enveric Biosciences Canada Inc.

Inventor： Jillian M. Hagel ,  Peter J. Facchini ,  Chang-Chun Ling

IPC: C07D209/16

CPC classification number: C07D209/16

Abstract: Disclosed are novel aldehyde and ketone psilocybin derivative compounds and pharmaceutical and recreational drug formulations containing the same. The compounds may be produced by reacting a reactant psilocybin derivative with an aldehyde or ketone group containing compound.

公开(公告)号：US11845726B2

公开(公告)日：2023-12-19

申请号：US17893113

申请日：2022-08-22

Applicant: Enveric Biosciences Canada Inc.

Inventor： Jillian M. Hagel ,  Kaveh Matinkhoo ,  Peter J. Facchini

IPC: C07D209/16

CPC classification number: C07D209/16

Abstract: Disclosed are novel C4-carbonothioate-substituted tryptamine derivative compounds and pharmaceutical and recreational drug formulations containing the same. The pharmaceutical formulations may be used to treat brain neurological disorders.