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公开(公告)号:US09522920B2
公开(公告)日:2016-12-20
申请号:US14313148
申请日:2014-06-24
Applicant: Constellation Pharmaceuticals, Inc.
Inventor: Brian K. Albrecht , James Edmund Audia , Alexandre Côté , Victor S. Gehling , Jean-Christophe Harmange , Michael Charles Hewitt , Yves Leblanc , Christopher G. Nasveschuk , Alexander M. Taylor , Rishi G. Vaswani
IPC: A61K31/55 , C07D498/04 , C07D498/14 , C07D498/20 , C07D498/22 , C07K14/47 , A61K31/424
CPC classification number: C07D498/04 , A61K31/424 , A61K31/55 , C07D498/14 , C07D498/20 , C07D498/22 , C07K14/4702
Abstract: The present invention relates to compounds useful as inhibitors of bromodomain-containing proteins. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
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公开(公告)号:US20160333016A1
公开(公告)日:2016-11-17
申请号:US15155749
申请日:2016-05-16
Applicant: Constellation Pharmaceuticals, Inc.
Inventor: Brian K. Albrecht , James Edmund Audia , Andrew Cook , Les A. Dakin , Martin Duplessis , Victor S. Gehling , Jean-Christophe Harmange , Christopher G. Nasveschuk , Rishi G. Vaswani
IPC: C07D487/04 , C07D405/14 , C07D401/14 , C07D401/12 , C07D471/04
CPC classification number: A61K31/4545 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/06 , C07D417/04 , C07D417/14 , C07D471/04 , C07D487/04
Abstract: Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
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公开(公告)号:US09371331B2
公开(公告)日:2016-06-21
申请号:US14661797
申请日:2015-03-18
Applicant: Constellation Pharmaceuticals, Inc.
Inventor: Brian K. Albrecht , James Edmund Audia , Andrew S. Cook , Les A. Dakin , Martin Duplessis , Victor S. Gehling , Jean-Christophe Harmange , Christopher G. Nasveschuk , Rishi G. Vaswani
IPC: A61K31/535 , C07D401/00 , C07D487/04 , C07D401/14 , C07D401/12 , C07D417/04 , C07D417/14 , C07D405/14 , C07D409/06 , C07D471/04
CPC classification number: A61K31/4545 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/06 , C07D417/04 , C07D417/14 , C07D471/04 , C07D487/04
Abstract: Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
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公开(公告)号:US09206128B2
公开(公告)日:2015-12-08
申请号:US14358558
申请日:2012-11-19
Applicant: Constellation Pharmaceuticals, Inc.
Inventor: Brian K. Albrecht , James Edmund Audia , Andrew S. Cook , Alexandre Gagnon , Jean-Christophe Harmange , Christopher G. Nasveschuk
IPC: C07D213/61 , C07D213/64 , C07D221/18 , C07D401/12 , C07D405/12 , C07D413/12
CPC classification number: C07D213/64 , C07D221/18 , C07D401/12 , C07D405/12 , C07D413/12
Abstract: Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
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35.Modulators of methyl modifying enzymes, compositions and uses thereof 有权
Title translation: 甲基修饰酶的调节剂,组合物及其用途公开(公告)号:US09051269B2
公开(公告)日:2015-06-09
申请号:US14358455
申请日:2012-11-19
Applicant: Constellation Pharmaceuticals, Inc.
Inventor: Brian K. Albrecht , James Edmund Audia , Alexandre Gagnon , Jean-Christophe Harmange , Christopher G. Nasveschuk
IPC: C07D213/62 , C07D213/64 , C07D405/12 , C07D401/12
CPC classification number: C07D213/64 , C07D213/81 , C07D401/12 , C07D405/12
Abstract: Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
Abstract translation: 本文提供了用于调节甲基修饰酶的组合物及其用途。
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公开(公告)号:US20170312262A9
公开(公告)日:2017-11-02
申请号:US15155749
申请日:2016-05-16
Applicant: Constellation Pharmaceuticals, Inc.
Inventor: Brian K. Albrecht , James Edmund Audia , Andrew Cook , Les A. Dakin , Martin Duplessis , Victor S. Gehling , Jean-Christophe Harmange , Christopher G. Nasveschuk , Rishi G. Vaswani
IPC: A61K31/4545 , C07D417/14 , C07D417/04 , C07D409/06 , C07D405/14 , C07D401/14 , C07D401/12 , C07D471/04 , C07D487/04
CPC classification number: A61K31/4545 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/06 , C07D417/04 , C07D417/14 , C07D471/04 , C07D487/04
Abstract: Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
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公开(公告)号:US09409865B2
公开(公告)日:2016-08-09
申请号:US14707874
申请日:2015-05-08
Applicant: Constellation Pharmaceuticals, Inc.
Inventor: Brian K. Albrecht , James Edmund Audia , Alexandre Gagnon , Jean-Christophe Harmange , Christopher G. Nasveschuk
IPC: C07D213/62 , C07D213/64 , C07D213/81 , C07D405/12 , C07D401/12
CPC classification number: C07D213/64 , C07D213/81 , C07D401/12 , C07D405/12
Abstract: Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
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公开(公告)号:US20160009718A1
公开(公告)日:2016-01-14
申请号:US14769471
申请日:2014-03-12
Applicant: CONSTELLATION PHARMACEUTICALS, INC.
Inventor: Brian K. Albrecht , James Edmund Audia , Andrew Cook , Alexandre Côté , Les A. Dakin , Victor S. Gehling , Jean-Christophe Harmange , Christopher G. Nasveschuk , Rishi G. Vaswani
IPC: C07D487/04
CPC classification number: C07D487/04
Abstract: Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
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公开(公告)号:US20150259351A1
公开(公告)日:2015-09-17
申请号:US14661797
申请日:2015-03-18
Applicant: Constellation Pharmaceuticals, Inc.
Inventor: Brian K. Albrecht , James Edmund Audia , Andrew S. Cook , Les A. Dakin , Martin Duplessis , Victor S. Gehling , Jean-Christophe Harmange , Christopher G. Nasveschuk , Rishi G. Vaswani
IPC: C07D487/04 , C07D409/06 , C07D401/14 , C07D405/14 , C07D401/12 , C07D471/04
CPC classification number: A61K31/4545 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/06 , C07D417/04 , C07D417/14 , C07D471/04 , C07D487/04
Abstract: Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
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公开(公告)号:US09085583B2
公开(公告)日:2015-07-21
申请号:US14377214
申请日:2013-02-11
Applicant: Constellation—Pharmaceuticals, Inc.
Inventor: Brian K. Albrecht , James Edmund Audia , Andrew S. Cook , Les A. Dakin , Martin Duplessis , Victor S. Gehling , Jean-Christophe Harmange , Christopher G. Nasveschuk , Rishi G. Vaswani
IPC: A61K31/535 , C07D401/00 , C07D487/04 , C07D401/14 , C07D401/12 , C07D417/04 , C07D417/14
CPC classification number: A61K31/4545 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/06 , C07D417/04 , C07D417/14 , C07D471/04 , C07D487/04
Abstract: Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
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