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公开(公告)号:US20100075299A1
公开(公告)日:2010-03-25
申请号:US12303942
申请日:2007-06-04
申请人: Angeline Ingrid Bartholomeusz , Stephen Locarnini , Anna Ayre , Lilly Ka Wai Yuen , Peter William Angus , Joseph John Sasadeusz , Paul Desmond , Hans Tillman , Thomas Bock , William Sievert , Sharon Lewin
发明人: Angeline Ingrid Bartholomeusz , Stephen Locarnini , Anna Ayre , Lilly Ka Wai Yuen , Peter William Angus , Joseph John Sasadeusz , Paul Desmond , Hans Tillman , Thomas Bock , William Sievert , Sharon Lewin
CPC分类号: C12Q1/706 , A61K39/12 , A61K39/29 , C07K14/005 , C12N7/00 , C12N2730/10122 , C12N2730/10134 , C12Q2600/156
摘要: The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B virus (HBV) variants exhibiting complete or partial resistance to nucleoside or nucleotide analogs and/or reduced interactivity with antibodies to viral surface components including reduced sensitivity to these antibodies. Vaccines and diagnostic assays are also contemplated herein.
摘要翻译: 本发明一般涉及对特定试剂表现出降低的敏感性和/或降低与免疫试剂的相互作用的病毒变体。 更具体地,本发明涉及对核苷或核苷酸类似物表现出完全或部分抗性和/或与抗体对抗病毒表面成分的降低的交互性的乙型肝炎病毒(HBV)变体,包括对这些抗体的敏感性降低。 疫苗和诊断测定也在本文中考虑。
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公开(公告)号:US4907762A
公开(公告)日:1990-03-13
申请号:US280129
申请日:1988-12-05
申请人: Thomas Bock , Gunther Schwertfeger
发明人: Thomas Bock , Gunther Schwertfeger
CPC分类号: B64D11/003
摘要: The invention is directed to a luggage rack for vehicles, especially aircraft, which is subdivided into individual compartments by means of separation walls and is arranged in the longitudinal direction of the vehicle with an overhead configuration with respect to the passengers and whose individual compartments are respectively closeable by means of a lid.
摘要翻译: 本发明涉及一种用于车辆,特别是飞机的行李架,其通过分隔壁被分为单独的隔室,并且沿着车辆的纵向方向布置有相对于乘客的顶置结构,并且其各个隔间分别 可以通过盖子关闭。
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公开(公告)号:US4202339A
公开(公告)日:1980-05-13
申请号:US970894
申请日:1978-12-19
申请人: Alexander Wirtzfeld , Thomas Bock
发明人: Alexander Wirtzfeld , Thomas Bock
CPC分类号: A61B5/02433 , A61B5/1459 , A61N1/36557
摘要: A cardiac pacemaker includes means for conforming the stimulation frequency to the bodily stressing conditions of the wearer of the pacemaker in using a blood parameter as measuring value for the influencing of the frequency of stimulation. A measuring probe is implanted in the heart of the wearer of the pacemaker for measuring the oxygen saturation of the blood. The measuring value thereby resulting serves as measuring parameter for the influencing of the frequency of stimulation.
摘要翻译: 心脏起搏器包括在使用血液参数作为影响刺激频率的测量值时使刺激频率与起搏器的佩戴者的身体应激条件一致的装置。 将测量探针植入起搏器穿戴者的心脏中,以测量血液的氧饱和度。 由此产生的测量值用作影响刺激频率的测量参数。
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