公开(公告)号：US20210040489A1

公开(公告)日：2021-02-11

申请号：US17072023

申请日：2020-10-15

Applicant: Inscripta, Inc.

Inventor： Tian Tian ,  Charles Johnson ,  Eileen Spindler

IPC: C12N15/70 ,  C12N9/22 ,  C12N15/113

Abstract: The present disclosure provides automated multi-module instrumentation and automated methods for performing recursive editing of live cells with curing of editing vectors from prior rounds of editing.

公开(公告)号：US20210010006A1

公开(公告)日：2021-01-14

申请号：US16917905

申请日：2020-07-01

Applicant: Inscripta, Inc.

Inventor： Miles Gander ,  Tian Tian ,  Eileen Spindler

IPC: C12N15/62 ,  C12N15/81

Abstract: The present disclosure provides compositions and methods to increase the percentage of edited yeast cells in a cell population when employing nucleic acid-guided editing, and automated multi-module instruments for performing these methods.

公开(公告)号：US20200056139A1

公开(公告)日：2020-02-20

申请号：US16536049

申请日：2019-08-08

Applicant: Inscripta, Inc.

Inventor： Andrew Garst ,  Michael Graige ,  Richard Fox ,  Eileen Spindler ,  Amy Hiddessen ,  Phillip Belgrader ,  Don Masquelier ,  Bruce Chabansky

IPC: C12M1/42 ,  C12N15/11 ,  C12M1/26 ,  C12N15/90 ,  C12M3/00

Abstract: The present disclosure provides automated modules and instruments for improved detection of nuclease genome editing of live cells. The disclosure provides improved modules—including high throughput modules—for screening cells that have been subjected to editing and identifying and selecting cells that have been properly edited.