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公开(公告)号：US20070275938A1
公开(公告)日：2007-11-29
申请号：US11674128
申请日：2007-02-12
申请人： Christopher Reading , Clarence Ahlem , Dominick Auci , Charles Dowding , James Frincke , Mei Li , Theodore Page , Dwight Stickney , Richard Trauger , Steven White
发明人： Christopher Reading , Clarence Ahlem , Dominick Auci , Charles Dowding , James Frincke , Mei Li , Theodore Page , Dwight Stickney , Richard Trauger , Steven White
摘要： The invention relates to the use of compounds to ameliorate or treat a condition such as a cystic fibrosis, neutropenia or other exemplified conditions. Exemplary compounds that can be used include 3β-hydroxy-17β-aminoandrost-5-ene, 3β-hydroxy-16α-fluoro-17β-aminoandrost-5-ene, 3α-hydroxy-16α-fluoro-17β-aminoandrost-5-ene, 3β-hydroxy-16β-fluoro-17β-aminoandrost-5-ene, 1α,3β-dihydroxy-4α-fluoroandrost-5-ene-17-one, 1α,3β,17β-trihydroxy-4α-fluoroandrost-5-ene, 1β,3β-dihydroxy-6α-bromoandrost-5-ene, 1α-fluoro-3β,12α-dihydroxyandrost-5-ene-17-one, 1α-fluoro-3β,4α-dihydroxyandrost-5-ene and 4α-fluoro-3β,6α,17β-trihydroxyandrostane.
摘要翻译： 本发明涉及化合物用于改善或治疗诸如囊性纤维化，中性粒细胞减少症或其它示例性病症的病症的用途。 可以使用的示例性化合物包括3β-羟基-17β-氨基雄甾-5-烯，3β-羟基-16α-氟-17β-氨基雄甾-5-烯，3α-羟基-16α-氟-17β-氨基雄甾-5-烯 ，3β-羟基-16β-氟-17β-氨基雄甾-5-烯，1α，3β-二羟基-4α-氟代雄甾-5-烯-17-酮，1α，3β，17β-三羟基-4α-氟代雄甾-5-烯 ，1beta，3β-二羟基-6α-溴代雄甾-5-烯，1α-氟-3β，12α-二羟基雄甾-5-烯-17-酮，1α-氟-3β，4α-二羟基雄甾-5-烯和4α-氟 -3β，6α，17β-三羟基雄甾烷。
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公开(公告)号：US20070035752A1
公开(公告)日：2007-02-15
申请号：US11203740
申请日：2005-08-15
申请人： Glenn Evans , Benjamin Ellett , David Blythe , Anantha Kancherla , Bradley Gibson , Michael Stokes , Steven White , Denis Demandolx
发明人： Glenn Evans , Benjamin Ellett , David Blythe , Anantha Kancherla , Bradley Gibson , Michael Stokes , Steven White , Denis Demandolx
IPC分类号： H04N1/60
CPC分类号： H04N1/603
摘要： Methods for mapping color data having at least one color associated therewith to an output device based on an input device profile and an output device profile, each profile having a tone curve and a color matrix, are provided. In one embodiment, the method includes receiving color data from an input device and determining whether the color data is in a linear space. If it is determined that the color data is not in a linear space, the method further includes applying the tone curve of the input device profile to the color data to convert it into a linear space. The method further includes converting the color(s) associated with the color data from the input linear space to an output linear space by applying the color matrix of the input device profile and the inverse color matrix of the output device profile to create color-converted image data.
摘要翻译： 提供了基于输入设备配置文件和输出设备配置文件将具有与其相关联的至少一种颜色的颜色数据映射到输出设备的方法，每个配置文件具有色调曲线和颜色矩阵。 在一个实施例中，该方法包括从输入装置接收彩色数据并确定彩色数据是否处于线性空间。 如果确定颜色数据不在线性空间中，则该方法还包括将输入设备简档的色调曲线应用于颜色数据以将其转换为线性空间。 该方法还包括通过应用输出设备配置文件的颜色矩阵和输出设备配置文件的反色矩阵来将与输入线性空间的颜色数据相关联的颜色转换为输出线性空间，以创建颜色转换 图像数据。
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公开(公告)号：US20060290705A1
公开(公告)日：2006-12-28
申请号：US11166761
申请日：2005-06-24
申请人： Steven White , Donald Marsh , Douglas Ricard , Jingyang Xu
发明人： Steven White , Donald Marsh , Douglas Ricard , Jingyang Xu
CPC分类号： G06T1/60 , G06T11/60 , G06T15/503
摘要： Methods for processing, e.g., non-destructively processing, digital image data utilizing an Effect graph are provided. In one embodiment, the method may include receiving an Effect graph including a plurality of Effect objects each having an image buffer associated therewith for storing digital image data, receiving digital image data to be processed utilizing the Effect graph, and performing a pre-rendering pass of the Effect graph prior to processing the digital image data. The pre-rendering pass may be utilized, for instance, to determine at which Effects a cache should be held to alleviate exponential rendering, and the like. Systems for performing the methods herein described are also provided.
摘要翻译： 提供了使用效果图来处理，例如非破坏性处理数字图像数据的方法。 在一个实施例中，该方法可以包括接收包括多个效果对象的效果图，每个效果对象具有与之相关联的图像缓冲器用于存储数字图像数据，接收使用该效果图来处理的数字图像数据，以及执行预渲染传递 在处理数字图像数据之前的效果图。 例如，可以利用预呈现遍历来确定应该在哪个效果上保持缓存以减轻指数呈现等。 还提供了用于执行本文所述方法的系统。
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公开(公告)号：US20060195531A1
公开(公告)日：2006-08-31
申请号：US11068583
申请日：2005-02-28
申请人： David Braun , Daniel Longley , Malcolm Pearson , Steven White
发明人： David Braun , Daniel Longley , Malcolm Pearson , Steven White
IPC分类号： G06F15/16
CPC分类号： G06Q10/107 , H04L12/1877 , H04L51/00
摘要： Within a mail transfer agent of a message transfer system, a message is received and if the recipient entity resolves to a number of recipients exceeding a specified quantity, the original message is not processed. Instead, at least two messages are created, with each of the created messages addressed to a subset of the original set of recipients. The created messages are returned to the calling module for processing.
摘要翻译： 在消息传送系统的邮件传送代理内，接收到消息，如果接收者实体解析为超过指定数量的多个接收者，则不处理原始消息。 而是创建至少两个消息，每个创建的消息都被寻址到原始收件人集的一个子集。 创建的消息将返回到调用模块进行处理。
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公开(公告)号：US20060195530A1
公开(公告)日：2006-08-31
申请号：US11068549
申请日：2005-02-28
申请人： David Braun , Daniel Longley , Malcolm Pearson , Steven White
发明人： David Braun , Daniel Longley , Malcolm Pearson , Steven White
IPC分类号： G06F15/16
CPC分类号： H04L51/30 , H04L51/063 , H04L51/066
摘要： Within a mail transfer agent of a message transfer system, a message is received and if the recipient entity resolves to a number of recipients exceeding a specified quantity, the original message is not processed. Instead, at least two messages are created, with each of the created messages addressed to a subset of the original set of recipients. The created messages are returned to the calling module for processing.
摘要翻译： 在消息传送系统的邮件传送代理内，接收到消息，如果接收者实体解析为超过指定数量的多个接收者，则不处理原始消息。 而是创建至少两个消息，每个创建的消息都被寻址到原始收件人集的一个子集。 创建的消息将返回到调用模块进行处理。
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公开(公告)号：US20060195529A1
公开(公告)日：2006-08-31
申请号：US11067776
申请日：2005-02-28
申请人： David Braun , Daniel Longley , Malcolm Pearson , Steven White
发明人： David Braun , Daniel Longley , Malcolm Pearson , Steven White
IPC分类号： G06F15/16
CPC分类号： H04L51/28 , H04L51/063 , H04L51/066
摘要： Within a mail transfer agent of a message transfer system, a message is received and if the recipient entity resolves to a number of recipients exceeding a specified quantity, the original message is not processed. Instead, at least two messages are created, with each of the created messages addressed to a subset of the original set of recipients. The created messages are returned to the calling module for processing.
摘要翻译： 在消息传送系统的邮件传送代理内，接收到消息，如果接收者实体解析为超过指定数量的多个接收者，则不处理原始消息。 而是创建至少两个消息，每个创建的消息都被寻址到原始收件人集的一个子集。 创建的消息将返回到调用模块进行处理。
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公开(公告)号：US20060068001A1
公开(公告)日：2006-03-30
申请号：US11280908
申请日：2005-11-16
申请人： Deborah Sherman , John Clark , John Lamer , Steven White
发明人： Deborah Sherman , John Clark , John Lamer , Steven White
IPC分类号： A61K9/62
CPC分类号： A61K9/1652 , A61K9/5047
摘要： This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, an antidepressant, which provides better control of blood plasma levels than conventional tablet formulations which must be administered two or more times a day and further provides a lower incidence of nausea and vomiting than the conventional tablets. More particularly, the invention comprises an extended release formulation of venlafaxine hydrochloride comprising a therapeutically effective amount of venlafaxine hydrochloride in spheroids comprised of venlafaxine hydrochloride, microcrystalline cellulose and, optionally, hydroxypropylmethylcellulose coated with a mixture of ethyl cellulose and hydroxypropylmethylcellulose.
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公开(公告)号：US20060067999A1
公开(公告)日：2006-03-30
申请号：US11280382
申请日：2005-11-16
申请人： Deborah Sherman , John Clark , John Lamer , Steven White
发明人： Deborah Sherman , John Clark , John Lamer , Steven White
IPC分类号： A61K9/62
CPC分类号： A61K9/1652 , A61K9/5047
摘要： This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, an antidepressant, which provides better control of blood plasma levels than conventional tablet formulations which must be administered two or more times a day and further provides a lower incidence of nausea and vomiting than the conventional tablets. More particularly, the invention comprises an extended release formulation of venlafaxine hydrochloride comprising a therapeutically effective amount of venlafaxine hydrochloride in spheroids comprised of venlafaxine hydrochloride, microcrystalline cellulose and, optionally, hydroxypropylmethylcellulose coated with a mixture of ethyl cellulose and hydroxypropylmethylcellulose.
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公开(公告)号：US20060062843A1
公开(公告)日：2006-03-23
申请号：US11274984
申请日：2005-11-16
申请人： Deborah Sherman , John Clark , John Lamer , Steven White
发明人： Deborah Sherman , John Clark , John Lamer , Steven White
CPC分类号： A61K9/1652 , A61K9/5047
摘要： This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, an antidepressant, which provides better control of blood plasma levels than conventional tablet formulations which must be administered two or more times a day and further provides a lower incidence of nausea and vomiting than the conventional tablets. More particularly, the invention comprises an extended release formulation of venlafaxine hydrochloride comprising a therapeutically effective amount of venlafaxine hydrochloride in spheroids comprised of venlafaxine hydrochloride, microcrystalline cellulose and, optionally, hydroxypropylmethylcellulose coated with a mixture of ethyl cellulose and hydroxypropylmethylcellulose.
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公开(公告)号：US20050256930A1
公开(公告)日：2005-11-17
申请号：US10822347
申请日：2004-04-12
CPC分类号： G06Q10/107 , H04L51/00 , H04L51/12
摘要： Provided is a messaging system capable of detecting and processing at least a portion of a malformed message, e.g., a message that previously failed to process. An identifier and state information for the message can be logged. Based on the stored information, a determination can be made that the message previously failed to process. The message can then progressively be de-featured until the message can be processed or until the message is determined to be poisonous, whereupon it can be deleted or otherwise removed from the message stream permanently or temporarily-including moving the message to storage for operator inspection or for delayed delivery.
摘要翻译： 提供了能够检测和处理畸形消息的至少一部分的消息系统，例如先前不能处理的消息。 可以记录消息的标识符和状态信息。 基于所存储的信息，可以确定先前无法处理该消息。 然后可以逐渐取消消息，直到消息可以被处理或直到消息被确定为有毒，从而可以永久或暂时地从消息流中删除或以其他方式删除该消息，包括将消息移动到存储器以进行操作者检查 或延迟交货。
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