Synergistic anti-inflammatory pharmaceutical compositions and methods of use
    31.
    发明申请
    Synergistic anti-inflammatory pharmaceutical compositions and methods of use 审中-公开
    协同抗炎药物组合物和使用方法

    公开(公告)号:US20050192356A1

    公开(公告)日:2005-09-01

    申请号:US10789814

    申请日:2004-02-27

    摘要: The invention provides a composition comprising a reduced isoalpha acid (RIAA) and isoalpha acid (IAA) isolated from hops, wherein the RIAA and IAA are in a ratio of about 3:1 to about 1:10. The invention also provides a method of reducing inflammation by administering a composition comprising a reduced isoalpha acid (RIAA) and isoalpha acid (IAA) isolated from hops, wherein the RIAA and IAA are in a ratio of about 3:1 to about 1:10.

    摘要翻译: 本发明提供一种组合物,其包含从啤酒花中分离的还原异α酸(RIAA)和异α-酸(IAA),其中RIAA和IAA的比例为约3:1至约1:10。 本发明还提供了一种通过施用包含从啤酒花中分离的还原异α酸(RIAA)和异α-酸(IAA)的组合物来减轻炎症的方法,其中RIAA和IAA的比例为约3:1至约1:10 。

    Complex Mixtures Exhibiting Selective Inhibition of Cyclooxygenase-2
    35.
    发明申请
    Complex Mixtures Exhibiting Selective Inhibition of Cyclooxygenase-2 审中-公开
    复合混合物显示环氧合酶-2的选择性抑制

    公开(公告)号:US20070172532A1

    公开(公告)日:2007-07-26

    申请号:US11623400

    申请日:2007-01-16

    申请人: John Babish M. Howell

    发明人: John Babish M. Howell

    IPC分类号: A61K36/185

    摘要: A novel formulation is provided that serves to specifically inhibit the COX-2 mediated inflammatory response in animals. The formulation comprises an effective amount of component I selected from the group consisting of alpha acids and beta acids and an effective amount of at least one component II selected from the group consisting of alpha acids, beta acids, essential oils, fats and waxes, with the proviso that component I and II are not the same compound. The composition provides specific inhibition of cyclooxygenase-2 with little or no effect on cyclooxygenase-1.

    摘要翻译: 提供了用于特异性抑制动物中COX-2介导的炎性反应的新型制剂。 该制剂包含有效量的选自α酸和β酸的组分I和有效量的至少一种选自α酸,β酸,精油,脂肪和蜡的组分II,其中 条件是组分I和II不是相同的化合物。 该组合物对环加氧酶-2的特异性抑制作用,对环氧合酶-1几乎没有或没有影响。

    Arginine compositions for coordinate modification of multiple cardiovascular risk factors
    37.
    发明申请
    Arginine compositions for coordinate modification of multiple cardiovascular risk factors 审中-公开
    用于协调改变多种心血管危险因素的精氨酸组合物

    公开(公告)号:US20050233944A1

    公开(公告)日:2005-10-20

    申请号:US11141085

    申请日:2005-05-31

    申请人: John Babish

    发明人: John Babish

    摘要: The present invention relates generally to compositions and methods for coordinate reduction of the serum levels of cardiovascular arterial disease risk factors, such as total cholesterol, LDL cholesterol, HDL/LDL ratio, triglycerides, homocysteine, and C-reactive protein. The composition comprises an arginine compound and another member selected from high molecular weight aliphatic alcohol or methyl donor cofactor, such as folic acid, vitamin B6, vitamin B12 or derivatives thereof. The compositions function coordinately to modify multiple serum cardiovascular risk factors.

    摘要翻译: 本发明一般涉及用于协调降低心血管动脉疾病危险因素如总胆固醇,低密度脂蛋白胆固醇,HDL / LDL比,甘油三酸酯,高半胱氨酸和C-反应蛋白的血清水平的组合物和方法。 组合物包含精氨酸化合物和选自高分子量脂肪醇或甲基供体辅因子(如叶酸,维生素B6,维生素B12或其衍生物)的另一种成分。 组合物协调地调节多种血清心血管危险因素。