公开(公告)号：US20240148814A1

公开(公告)日：2024-05-09

申请号：US18280505

申请日：2022-03-11

申请人： Manda Fermentation Co., Ltd.

发明人： SHINSUKE KISHIDA ,  KOTARO FUJIOKA ,  HIDETO TORII ,  HUANG CHUN-MING

IPC分类号： A61K36/73 ,  A61K36/23 ,  A61K36/44 ,  A61K36/45 ,  A61K36/60 ,  A61K36/71 ,  A61K36/752 ,  A61K36/87 ,  A61K36/899 ,  A61K36/906

CPC分类号： A61K36/73 ,  A61K36/23 ,  A61K36/44 ,  A61K36/45 ,  A61K36/60 ,  A61K36/71 ,  A61K36/752 ,  A61K36/87 ,  A61K36/899 ,  A61K36/906

摘要： To provide an inhibitor inhibiting a cytokine storm in a living body due to infectious disease. An inhibitor for inhibiting a cytokine storm includes a fermented composition as a main raw material, the fermented composition is obtained by fermentation and aging of a plurality of substances belonging to fruits, citrus fruits, burdock, and carrot belonging to root vegetables, cereals, sesames, seaweeds, and sugars.

公开(公告)号：US20230165925A1

公开(公告)日：2023-06-01

申请号：US17540201

申请日：2021-12-01

申请人： Meyer Health Jiangsu Co., Ltd.

发明人： Hanping SHI ,  Ru JIA

IPC分类号： A61K36/725 ,  A61K47/24 ,  A61K36/00 ,  A61K36/60 ,  A61K47/26 ,  A61K9/00 ,  A61P25/24 ,  A23L33/00 ,  A23L33/105 ,  A23L33/175 ,  A23L33/115 ,  A23L33/125

CPC分类号： A61K36/725 ,  A61K47/24 ,  A61K36/00 ,  A61K36/60 ,  A61K47/26 ,  A61K9/0056 ,  A61P25/24 ,  A23L33/40 ,  A23L33/105 ,  A23L33/175 ,  A23L33/115 ,  A23L33/125 ,  A61K2236/15 ,  A61K2236/333 ,  A61K2236/51 ,  A61K2236/39 ,  A61K2236/37 ,  A61K2236/53 ,  A23V2002/00

摘要： An antidepressant food and a method for preparing the same are provided. The antidepressant food includes, by mass percentage, Semen ziziphi spinosae powder in a range of 28% to 36%, γ-aminobutyric acid in a range of 10% to 15%, theanine in a range of 15% to 20%, phosphatidylserine in a range of 10% to 20%, Ficus tikoua extract in a range of 8% to 14%, Huperzia serrata extract in a range of 10% to 16%, sucralose in a range of 0.5% to 1% and fruit essence in a range of 0.5% to 1.5%.

公开(公告)号：US11298372B2

公开(公告)日：2022-04-12

申请号：US16885930

申请日：2020-05-28

申请人： National University Corporation Tokyo Medical and Dental University

发明人： Emi Nishimura ,  Hiroyuki Matsumura

IPC分类号： A61K31/713 ,  A61K38/55 ,  A61K36/05 ,  A61K36/14 ,  A61K36/47 ,  A61K36/48 ,  A61K36/54 ,  A61K8/97 ,  A61K31/506 ,  A61K36/489 ,  A61K36/738 ,  A61K36/04 ,  A61K36/424 ,  A61Q5/00 ,  A61K48/00 ,  A61K31/7088 ,  C12Q1/37 ,  A61K36/30 ,  A61K36/74 ,  A61K36/23 ,  A61K36/60 ,  A61K36/185 ,  A61Q7/00 ,  A61K36/718 ,  A61K36/488 ,  A61K36/53 ,  A61K36/82 ,  A61K39/395 ,  A61K36/18 ,  A61K36/28 ,  A61K31/222 ,  A61K45/00 ,  A61P17/14 ,  A61K31/05 ,  A61K31/16 ,  A61K31/355 ,  A61K31/375 ,  A61K31/381 ,  A61K31/7048 ,  A61K31/13 ,  A61K36/00

摘要： The present invention provides novel compositions for suppressing or improving hair loss, and compositions for suppressing or improving graying. More specifically, it provides agents that stabilize type XVII collagen expression, preferably agents that suppress the degradation of type XVII collagen by ELANE inhibitors and such, and compositions comprising a DNA repair-promoting agent or a DNA damage-suppressing agent as an active ingredient. Advantageous suppressive effects of hair loss and graying can be obtained when a composition comprising as an active ingredient a suppressive agent of type XVII collagen degradation such as an ELANE inhibitor is administered to a mammal. For the ELANE inhibitors, suppressive agents of type XVII collagen degradation and DNA repair-promoting agents, low-molecular compounds, polypeptides, proteins, antibodies, or nucleic acid medicine such as antisense oligos or siRNAs may be used. A method of screening for effective substances for suppression of hair loss and graying is also provided.

公开(公告)号：US11219660B2

公开(公告)日：2022-01-11

申请号：US15998364

申请日：2018-08-10

申请人： Tieh-Chun Tang

发明人： Tieh-Chun Tang

IPC分类号： A61K36/87 ,  A61K36/00 ,  A61K36/39 ,  A61P1/04 ,  A61K33/06 ,  A61K33/10 ,  A61K36/02 ,  A61K36/185 ,  A61K36/48 ,  A61K36/60 ,  A61K36/81

摘要： An acid-relief agent comprising a fermented vegetable extract obtained from a mixture of banana leaves, sweet potato roots, potato skin, seaweed, grape leaves, tendrils leaves, fig roots, emperor bean roots, and deep sea water; and nanocalcium mineral powder obtained from the thermal decomposition and grinding of a mixture of mica ore, mother of pearl, oyster shells. and oyster bay.

公开(公告)号：US11089794B2

公开(公告)日：2021-08-17

申请号：US16475187

申请日：2017-12-31

申请人： Sagrado Natural Tea Remedies

发明人： Ramon Sagrado

IPC分类号： A23F3/14 ,  A23F3/18 ,  A61K9/00 ,  A61K9/06 ,  A61K36/22 ,  A61K36/30 ,  A61K36/37 ,  A61K36/48 ,  A61K36/60 ,  A61K36/61

摘要： Therapeutic tea remedy mixtures in the form of beverages and ointments. Methods for making the tea remedy mixtures are described along with the benefits it provides to combat various medical ailments that frequently impair the human body.

公开(公告)号：US20200038467A1

公开(公告)日：2020-02-06

申请号：US16471140

申请日：2016-12-22

申请人： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Mahadeva Nayak ,  Nagarajan Ananthanarayanan

发明人： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Mahadeva Nayak ,  Nagarajan Ananthanarayanan

IPC分类号： A61K36/60 ,  A61K31/352 ,  A61P17/10

摘要： Method of isolating natural molecules: α and β pyranocycloartobiloxanthone A and Artonine E, from the stem bark of Artocarpus hirsutus and their anti-acne potential by inhibiting the growth of Propionibacterium acnes thereof, are described.

公开(公告)号：US09610315B2

公开(公告)日：2017-04-04

申请号：US13144413

申请日：2010-01-15

申请人： Salvatore Munafo' ,  Luisa Rizza

发明人： Salvatore Munafo' ,  Luisa Rizza

IPC分类号： A61K9/00 ,  A01N43/16 ,  A61K36/00 ,  A61K9/02 ,  A61K9/48 ,  A61K36/63 ,  A61K47/10 ,  A61K36/33 ,  A61K36/60

CPC分类号： A61K36/60

摘要： Oral pharmaceutical, nutraceutical, health foods and medical device compositions based on polysaccharides from Opuntia Ficus Indica cladodes in combination with other active substances are useful for the prevention or treatment of GERD (Gastro-Esophageal Reflux Disease), gastric esophagitis and related diseases (e.g. dyspepsia, esophagitis, esofageal tumour, gastro-intestinal symptoms, chronic pharyngitis, Barrett's esophagus, esophageal adenocarcinoma, GERD-related pulmonary symptoms).

公开(公告)号：US09370544B2

公开(公告)日：2016-06-21

申请号：US14078053

申请日：2013-11-12

申请人： Unigen, Inc.

发明人： Qi Jia

IPC分类号： A01N65/00 ,  A61K36/539 ,  A61K31/35 ,  A61K36/11 ,  A61K36/15 ,  A61K36/185 ,  A61K36/28 ,  A61K36/47 ,  A61K36/48 ,  A61K36/484 ,  A61K36/486 ,  A61K36/53 ,  A61K36/54 ,  A61K36/60 ,  A61K36/906 ,  A61K36/9062

CPC分类号： A61K36/539 ,  A61K31/35 ,  A61K31/353 ,  A61K31/7048 ,  A61K36/11 ,  A61K36/15 ,  A61K36/185 ,  A61K36/28 ,  A61K36/47 ,  A61K36/48 ,  A61K36/484 ,  A61K36/486 ,  A61K36/53 ,  A61K36/54 ,  A61K36/60 ,  A61K36/74 ,  A61K36/906 ,  A61K36/9062

摘要： The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compounds—Free-B-ring flavonoids and flavans—for use in the prevention and treatment of diseases and conditions mediated by the COX-2 and 5-LO pathways. The present invention further provides a novel method for simultaneously inhibiting the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) enzymes, and reducing cox-2 mRNA production. Finally, the present invention includes a method for weight loss and blood glucose control. The methods of this invention are comprised of administering to a host in need thereof an effective amount of the composition of this invention together with a pharmaceutically acceptable carrier. This invention relates generally to the prevention and treatment of diseases and conditions mediated by the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) pathways, including but not limited to the relief joint discomfort and pain associated with conditions such as osteoarthritis, rheumatoid arthritis, and other injuries that result from overuse.

摘要翻译： 本发明提供由两种特定类别的化合物 - 游离B-环类黄酮和黄烷的混合物组成的新型组合物，用于预防和治疗由COX-2和5-LO介导的疾病和病症 途径。 本发明还提供了同时抑制环氧合酶-2（COX-2）和5-脂氧合酶（5-LO）酶，降低cox-2 mRNA产生的新方法。 最后，本发明包括减肥和血糖控制的方法。 本发明的方法包括向有需要的宿主施用有效量的本发明组合物和药学上可接受的载体。 本发明一般涉及由环氧合酶-2（COX-2）和5-脂氧合酶（5-LO）途径介导的疾病和病症的预防和治疗，包括但不限于与这样的病症有关的救济关节不适和疼痛 作为骨关节炎，类风湿性关节炎以及过度使用引起的其他损伤。

公开(公告)号：US20130101689A1

公开(公告)日：2013-04-25

申请号：US13808021

申请日：2011-07-04

申请人： Jin Young Lee ,  Hyang Tae Choi ,  Han Byul Kim ,  Ji Seong Kim

发明人： Jin Young Lee ,  Hyang Tae Choi ,  Han Byul Kim ,  Ji Seong Kim

IPC分类号： A61K36/60

CPC分类号： A61K36/605 ,  A61K8/0212 ,  A61K8/97 ,  A61K36/60 ,  A61K2800/78 ,  A61Q5/00 ,  A61Q5/12 ,  A61Q19/00 ,  A61Q19/008 ,  A61Q19/06 ,  A61Q19/08

摘要： The present invention relates to a composition containing a paper mulberry extract, and more particularly to a composition containing, as an active ingredient, a paper mulberry extract which has effects on enhancement of skin moisturization, inhibition of skin aging, alleviation of inflammation, antibacterial activity, pore size reduction, sebum control, skin complexion improvement, decomposition of subcutaneous fat, stimulation of melanin synthesis, and gray hair prevention.

摘要翻译： 本发明涉及一种含有桑叶提取物的组合物，更具体地说，涉及一种含有桑叶提取物作为活性成分的组合物，其具有增强皮肤保湿作用，抑制皮肤老化，减轻炎症，抗菌活性 ，孔径减少，皮脂控制，皮肤肤色改善，皮下脂肪分解，刺激黑色素合成和防止灰白色毛发。

公开(公告)号：US20090285917A1

公开(公告)日：2009-11-19

申请号：US12441689

申请日：2006-09-27

申请人： Jong Moon Jeong ,  Seung Sook Lee ,  Kyung Bum Kim ,  Eu Gene Lee

发明人： Jong Moon Jeong ,  Seung Sook Lee ,  Kyung Bum Kim ,  Eu Gene Lee

IPC分类号： A61K36/282 ,  A61K36/87 ,  A61K36/60 ,  A61P37/08 ,  A61P11/06 ,  A61P17/00

CPC分类号： A61K36/61 ,  A23L33/105 ,  A61K36/282 ,  A61K36/605 ,  A61K36/87 ,  A61K2300/00

摘要： A prevention and therapy pharmacy composition for allergic rhinitis, atopic dermatitis and asthma includes at least one crude drug extract selected from the group including wormwood, guava leaves, mulberry tree leaves and grape seeds as an effective component. The functional composition may be used for manufacturing a medicine composition and health function food with its anti-allergic rhinitis, anti-atopic dermatitis and anti-asthma activity effects.

摘要翻译： 用于过敏性鼻炎，特应性皮炎和哮喘的预防和治疗药物组合物包括至少一种选自包括蒿木，番石榴叶，桑树叶和葡萄籽作为有效成分的生药提取物。 功能组合物可以用于制造具有抗过敏性鼻炎，抗特应性皮炎和抗哮喘活性作用的药物组合物和保健功能食品。