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公开(公告)号：US20080031894A1
公开(公告)日：2008-02-07
申请号：US11820755
申请日：2007-06-20
申请人： Matthew Tripp , John Babish , Jeffrey Bland , Veera Konda , Amy Hall , Linda Pacioretty , Anu Desai
发明人： Matthew Tripp , John Babish , Jeffrey Bland , Veera Konda , Amy Hall , Linda Pacioretty , Anu Desai
CPC分类号： A61K36/185
摘要： Compounds and methods for protein kinase modulation for cancer treatment are disclosed. The compounds and methods disclosed are based on beta acids, commonly found in hops.
摘要翻译： 公开了用于癌症治疗的蛋白激酶调节的化合物和方法。 所公开的化合物和方法基于通常在啤酒花中发现的β-酸。
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公开(公告)号：US20080031893A1
公开(公告)日：2008-02-07
申请号：US11820621
申请日：2007-06-20
申请人： Matthew Tripp , John Babish , Jeffrey Bland , Veera Konda , Amy Hall , Linda Pacioretty , Anu Desai
发明人： Matthew Tripp , John Babish , Jeffrey Bland , Veera Konda , Amy Hall , Linda Pacioretty , Anu Desai
CPC分类号： A61K36/185
摘要： Compounds and methods for protein kinase modulation for cancer treatment are disclosed. The compounds and methods disclosed are based on Acacia fractions, compounds, and extracts.
摘要翻译： 公开了用于癌症治疗的蛋白激酶调节的化合物和方法。 所公开的化合物和方法基于相思部分，化合物和提取物。
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3.发明申请Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes 有权用于治疗代谢综合征和糖尿病的抗炎植物产品公开(公告)号：US20070281045A1
公开(公告)日：2007-12-06
申请号：US11635305
申请日：2006-12-07
申请人： Matthew Tripp , John Babish , Jeffrey Bland , Amy Hall , Veera Konda , Linda Pacioretty
发明人： Matthew Tripp , John Babish , Jeffrey Bland , Amy Hall , Veera Konda , Linda Pacioretty
CPC分类号： A61K36/48 , A61K36/185 , A61K36/23 , A61K36/282 , A61K36/31 , A61K36/73 , A61K36/80 , A61K2300/00
摘要： Disclosed are botanically based compositions and methods useful for the treatment of metabolic syndrome and diabetes type 2. Compositions, kits, and methods are additionally disclosed for means to augment the activity of identified glucose and insulin regulating drugs.
摘要翻译： 公开了用于治疗代谢综合征和类型2的糖尿病的基于植物学的组合物和方法。另外公开了组合物，试剂盒和方法，以增加鉴定的葡萄糖和胰岛素调节药物的活性。
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4.发明申请公开(公告)号：US20060127514A1
公开(公告)日：2006-06-15
申请号：US11344556
申请日：2006-01-30
申请人： Matthew Tripp , John Babish , Jeffrey Bland , Gary Darland , Robert Lerman , Daniel Lukaczer , DeAnn Liska , Terrence Howell
发明人： Matthew Tripp , John Babish , Jeffrey Bland , Gary Darland , Robert Lerman , Daniel Lukaczer , DeAnn Liska , Terrence Howell
IPC分类号： A61K36/185 , A61K31/12
CPC分类号： A61K31/122 , A61K31/12 , A61K36/185 , A61K36/53 , A61K2300/00
摘要： A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
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5.发明申请公开(公告)号：US20080031982A1
公开(公告)日：2008-02-07
申请号：US11820600
申请日：2007-06-20
申请人： Matthew Tripp , John Babish , Jeffrey Bland , Veera Konda , Amy Hall , Linda Pacioretty , Anu Desai
发明人： Matthew Tripp , John Babish , Jeffrey Bland , Veera Konda , Amy Hall , Linda Pacioretty , Anu Desai
CPC分类号： A61K36/185
摘要： Compounds and methods for protein kinase modulation for cancer treatment are disclosed. The compounds and methods disclosed are based on tetrahydro-isoalpha acids, commonly found in hops.
摘要翻译： 公开了用于癌症治疗的蛋白激酶调节的化合物和方法。 所公开的化合物和方法是基于通常在啤酒花中发现的四氢异亮氨酸。
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6.发明申请公开(公告)号：US20070249728A1
公开(公告)日：2007-10-25
申请号：US10590301
申请日：2005-02-26
申请人： John Babish , Matthew Tripp , Jeffrey Bland
发明人： John Babish , Matthew Tripp , Jeffrey Bland
CPC分类号： A61K36/185 , A61K31/12 , A61K31/19 , A61K31/557 , A61K36/12 , A61K2300/00
摘要： The invention provides a composition comprising a reduced isoalpha acid (RIAA) and isoalpha acid (IAA) isolated from hops, wherein the RIAA and IAA are in a ratio of about 3:1 to about 1:10. The invention also provides a method of reducing inflammation by administering a composition comprising a reduced isoalpha acid (RIAA) and isoalpha acid (IAA) isolated from hops, wherein the RIAA and IAA are in a ratio of about 3:1 to about 1:10.
摘要翻译： 本发明提供一种组合物，其包含从啤酒花中分离的还原异α酸（RIAA）和异α-酸（IAA），其中RIAA和IAA的比例为约3:1至约1:10。 本发明还提供了一种通过施用包含从啤酒花中分离的还原异α酸（RIAA）和异α-酸（IAA）的组合物来减轻炎症的方法，其中RIAA和IAA的比例为约3:1至约1:10 。
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公开(公告)号：US20060127512A1
公开(公告)日：2006-06-15
申请号：US11344554
申请日：2006-01-30
申请人： Matthew Tripp , John Babish , Jeffrey Bland , Gary Darland , Robert Lerman , Daniel Lukaczer , DeAnn Liska , Terrence Howell
发明人： Matthew Tripp , John Babish , Jeffrey Bland , Gary Darland , Robert Lerman , Daniel Lukaczer , DeAnn Liska , Terrence Howell
IPC分类号： A61K36/185 , A61K31/12
CPC分类号： A61K36/185 , A61K31/12
摘要： A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops.
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公开(公告)号：US20080033056A1
公开(公告)日：2008-02-07
申请号：US11820747
申请日：2007-06-20
申请人： Matthew Tripp , John Babish , Jeffrey Bland , Veera Konda , Amy Hall , Linda Pacioretty , Anu Desai
发明人： Matthew Tripp , John Babish , Jeffrey Bland , Veera Konda , Amy Hall , Linda Pacioretty , Anu Desai
CPC分类号： A61K36/185
摘要： Compounds and methods for protein kinase modulation for cancer treatment are disclosed. The compounds and methods disclosed are based on xanthohumol or isoxantohumol, commonly found in hops.
摘要翻译： 公开了用于癌症治疗的蛋白激酶调节的化合物和方法。 所公开的化合物和方法基于黄曲霉醇或异山梨醇，其通常在啤酒花中发现。
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公开(公告)号：US20080031986A1
公开(公告)日：2008-02-07
申请号：US11823934
申请日：2007-06-29
申请人： Matthew Tripp , John Babish , Jeffrey Bland , Amy Hall , Veera Konda , Linda Pacioretty , Anu Desai
发明人： Matthew Tripp , John Babish , Jeffrey Bland , Amy Hall , Veera Konda , Linda Pacioretty , Anu Desai
IPC分类号： A61K36/48 , A61K31/122 , A61K31/352
CPC分类号： A61K36/185 , A61K31/12 , A61K36/48
摘要： Botanical compounds to modulate kinase activity are disclosed. The compounds and methods disclosed also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively. The compositions contain at least one fraction isolated or derived from hops or Acacia.
摘要翻译： 公开了调节激酶活性的植物化合物。 所公开的化合物和方法还抑制COX-2的表达，在靶细胞中选择性抑制前列腺素的合成，并且选择性地抑制炎症反应。 组合物含有至少一个分离或衍生自啤酒花或金合欢的馏分。
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10.发明申请Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines 有权协同抗炎药物组合物和使用姜黄素或甲基黄嘌呤的相关方法公开(公告)号：US20070185213A1
公开(公告)日：2007-08-09
申请号：US10590424
申请日：2005-02-26
申请人： John Babish , Matthew Tripp , Jeffrey Bland
发明人： John Babish , Matthew Tripp , Jeffrey Bland
IPC分类号： A61K31/12
CPC分类号： A61K31/522 , A61K31/12 , A61K31/19 , A61K36/185 , A61K36/9066 , A61K45/06 , A61K2300/00
摘要： The invention provides compositions containing a fraction isolated or derived from hops and a methylxanthine. The invention additionally provides compositions containing a fraction derived from hops and a curcuminoid. The invention also provides methods of using such compositions to reduce inflammation.
摘要翻译： 本发明提供了含有从啤酒花和甲基黄嘌呤中分离或衍生的级分的组合物。 本发明另外提供了含有源自啤酒花和姜黄素的级分的组合物。 本发明还提供了使用这种组合物减少炎症的方法。
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