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    Method and apparatus for post-shock evaluation using tissue oxygenation measurements
    32.
    发明授权
    Method and apparatus for post-shock evaluation using tissue oxygenation measurements 有权
    使用组织氧合测量进行休克后评估的方法和装置

    公开(公告)号：US08918171B2

    公开(公告)日：2014-12-23

    申请号：US12845843

    申请日：2010-07-29

    申请人： Jonathan L. Kuhn ,  Can Cinbis ,  David A. Anderson ,  William J. Havel

    发明人： Jonathan L. Kuhn ,  Can Cinbis ,  David A. Anderson ,  William J. Havel

    IPC分类号： A61N1/365 ,  A61N1/39 ,  A61B5/1455 ,  A61B5/00 ,  A61B5/1459

    CPC分类号： A61B5/14551 ,  A61B5/1459 ,  A61B5/6846 ,  A61B5/7285 ,  A61N1/36557 ,  A61N1/3925 ,  A61N1/3956

    摘要： A method and device for delivering therapy that includes an electrode to sense cardiac signals and to deliver a therapy, a monitoring module detecting a cardiac event in response to the sensed cardiac signals using first detection criteria, a sensor emitting light and detecting emitted light scattered by a tissue volume adjacent the sensor to generate a corresponding detected light intensity output signal, a control module coupled to the sensor to control light emission of the sensor in response to delivering the therapy, and a controller coupled to the monitoring module, the therapy delivery module and the sensor, the controller configured to determine tissue oxygenation measurements in response to the output signal, determine a tissue oxygenation trend in response to the tissue oxygenation measurements, determine a recovery index in response to the determined tissue oxygenation trend, and control one or both of detecting a cardiac event by the monitoring module and delivery of therapy by the therapy delivery module in response to the determined recovery index.

    摘要翻译： 一种用于递送疗法的方法和装置，其包括用于感测心脏信号并递送治疗的电极，监测模块，响应于使用第一检测标准的所感测到的心脏信号检测心脏事件，发射光并检测由 与所述传感器相邻的组织体积以产生相应的检测到的光强度输出信号;控制模块，耦合到所述传感器以响应于递送所述治疗来控制所述传感器的光发射;以及控制器，耦合到所述监测模块，所述治疗递送模块 以及所述传感器，所述控制器被配置为响应于所述输出信号确定组织氧合测量，响应于组织氧合测量确定组织氧合趋势，响应于所确定的组织氧合趋势确定恢复指数，并且控制一个或两个 通过监测模块检测心脏事件并进行治疗 y由治疗递送模块响应于确定的恢复指数。

    Method and apparatus for post-shock evaluation using tissue oxygenation measurements
    33.
    发明授权
    Method and apparatus for post-shock evaluation using tissue oxygenation measurements 有权
    使用组织氧合测量进行休克后评估的方法和装置

    公开(公告)号：US08639332B2

    公开(公告)日：2014-01-28

    申请号：US12845830

    申请日：2010-07-29

    申请人： Jonathan L. Kuhn ,  Can Cinbis ,  David A. Anderson ,  William J. Havel

    发明人： Jonathan L. Kuhn ,  Can Cinbis ,  David A. Anderson ,  William J. Havel

    IPC分类号： A61N1/365

    CPC分类号： A61B5/14551 ,  A61B5/1459 ,  A61B5/6846 ,  A61B5/7285 ,  A61N1/36557 ,  A61N1/3925 ,  A61N1/3956

    摘要： A method and device for delivering therapy that includes an electrode to sense cardiac signals and to deliver a therapy, a therapy delivery module coupled to the electrode to deliver a therapy via the electrode in response to the sensed cardiac signals, a sensor emitting light and detecting emitted light scattered by a tissue volume adjacent the optical sensor to generate a corresponding detected light intensity output signal, a control module coupled to the sensor to control light emission of the sensor in response to delivering the therapy, and a controller coupled to the therapy delivery module and the sensor, the controller configured to determine tissue oxygenation measurements in response to the output signal, determine a tissue oxygenation trend in response to the tissue oxygenation measurements, and determine whether the delivered therapy restored cardiac hemodynamic function in response to the determined tissue oxygenation trend.

    摘要翻译： 一种用于递送治疗的方法和装置，其包括用于感测心脏信号并递送治疗的电极，治疗递送模块，其耦合到所述电极，以响应于感测到的心脏信号经由所述电极递送治疗;发射光和检测的传感器 发射由邻近光学传感器的组织体积散射的光，以产生对应的检测到的光强度输出信号;耦合到传感器的控制模块，以响应于递送治疗来控制传感器的光发射;以及耦合到治疗传递的控制器 模块和传感器，所述控制器被配置为响应于所述输出信号确定组织氧合测量，响应于所述组织氧合测量确定组织氧合趋势，并且确定所递送的治疗是否响应于所确定的组织氧合来恢复心脏血液动力学功能 趋势。

    Active noise cancellation in an optical sensor signal
    34.
    发明授权
    Active noise cancellation in an optical sensor signal 有权
    光学传感器信号中的主动噪声消除

    公开(公告)号：US08352008B2

    公开(公告)日：2013-01-08

    申请号：US12797831

    申请日：2010-06-10

    申请人： Jonathan L. Kuhn ,  David A. Anderson ,  Can Cinbis

    发明人： Jonathan L. Kuhn ,  David A. Anderson ,  Can Cinbis

    IPC分类号： A61B5/00

    CPC分类号： A61B5/1459 ,  A61B5/1495

    摘要： A medical device system and associated method are used for monitoring tissue oxygenation. An optical sensor produces a signal corresponding to tissue light attenuation. A processor receives the optical sensor signal and computes a first measure of light attenuation at a first light wavelength and a second measure of light attenuation at a second light wavelength. In one embodiment, noise cancellation circuitry receives the first measure and the second measure and generates a guessed ratio of the first and second measures. Using the first measure, the second measure and the guessed ratio, the noise cancellation circuitry provides a peak output power when the guessed ratio corresponds to an actual ratio of the first and second measures.

    摘要翻译： 医疗器械系统和相关方法用于监测组织氧合。 光学传感器产生对应于组织光衰减的信号。 处理器接收光学传感器信号并且计算第一光波长处的光衰减的第一测量值和在第二光波长处的光衰减的第二测量值。 在一个实施例中，噪声消除电路接收第一测量和第二测量并产生第一和第二测量的猜测比率。 使用第一测量，第二测量和猜测比率，当猜测比率对应于第一和第二测量的实际比率时，噪声消除电路提供峰值输出功率。

    METHOD AND APPARATUS FOR POST-SHOCK EVALUATION USING TISSUE OXYGENATION MEASUREMENTS
    35.
    发明申请
    METHOD AND APPARATUS FOR POST-SHOCK EVALUATION USING TISSUE OXYGENATION MEASUREMENTS 有权
    使用组织氧化测量法进行后期评估的方法和装置

    公开(公告)号：US20110066198A1

    公开(公告)日：2011-03-17

    申请号：US12845830

    申请日：2010-07-29

    申请人： Jonathan L. Kuhn ,  Can Cinbis ,  David A. Anderson ,  William J. Havel

    发明人： Jonathan L. Kuhn ,  Can Cinbis ,  David A. Anderson ,  William J. Havel

    IPC分类号： A61N1/36

    CPC分类号： A61B5/14551 ,  A61B5/1459 ,  A61B5/6846 ,  A61B5/7285 ,  A61N1/36557 ,  A61N1/3925 ,  A61N1/3956

    摘要： A method and device for delivering therapy that includes an electrode to sense cardiac signals and to deliver a therapy, a therapy delivery module coupled to the electrode to deliver a therapy via the electrode in response to the sensed cardiac signals, a sensor emitting light and detecting emitted light scattered by a tissue volume adjacent the optical sensor to generate a corresponding detected light intensity output signal, a control module coupled to the sensor to control light emission of the sensor in response to delivering the therapy, and a controller coupled to the therapy delivery module and the sensor, the controller configured to determine tissue oxygenation measurements in response to the output signal, determine a tissue oxygenation trend in response to the tissue oxygenation measurements, and determine whether the delivered therapy restored cardiac hemodynamic function in response to the determined tissue oxygenation trend.

    摘要翻译： 一种用于递送治疗的方法和装置，其包括用于感测心脏信号并递送治疗的电极，治疗递送模块，其耦合到所述电极，以响应于感测到的心脏信号经由所述电极递送治疗;发射光和检测的传感器 发射由邻近光学传感器的组织体积散射的光，以产生对应的检测到的光强度输出信号;耦合到传感器的控制模块，以响应于递送治疗来控制传感器的光发射;以及耦合到治疗传递的控制器 模块和传感器，所述控制器被配置为响应于所述输出信号确定组织氧合测量，响应于所述组织氧合测量确定组织氧合趋势，并且确定所递送的治疗是否响应于所确定的组织氧合来恢复心脏血液动力学功能 趋势。