公开(公告)号：US12121368B2

公开(公告)日：2024-10-22

申请号：US17095101

申请日：2020-11-11

Applicant: International Business Machines Corporation

Inventor： Bing Dang ,  Rajeev Narayanan ,  Jeffrey L. Rogers

IPC: A61B5/00 ,  A61B5/01 ,  A61B5/0534 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/08 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/22

CPC classification number: A61B5/682 ,  A61B5/002 ,  A61B5/01 ,  A61B5/0534 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/0816 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/1473 ,  A61B5/228 ,  A61B5/4277 ,  A61B5/4542 ,  A61B5/4818 ,  A61B5/4884 ,  A61B2562/0247 ,  A61B2562/0261 ,  A61B2562/028 ,  A61B2562/16

Abstract: Embodiments of the present invention provide an oral device. According to one embodiment of the present invention, a mouthpiece suitable to detachably engage teeth of an upper jaw is provided. The mouthpiece comprises an adhesive layer configured to attach a hermetically sealed chamber to the mouthpiece. The hermitically sealed chamber fits within a concave space created by the mouthpiece. The hermitically sealed chamber comprises two layers and embedded between those two layers are a pressure sensor, a microphone, an optical sensor, a temperature sensor, a communications module, a storage enclosure, and a biosensor. Each of the pressure sensor, the microphone, the optical sensor, the temperature sensor, the communications module, the storage enclosure, and the biosensor are operably connected within the hermetically sealed chamber.

公开(公告)号：US20240324912A1

公开(公告)日：2024-10-03

申请号：US18576092

申请日：2021-08-06

Applicant: MEDTRUM TECHNOLOGIES INC.

Inventor： Cuijun Yang

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1495

CPC classification number: A61B5/14546 ,  A61B5/1495 ,  A61B5/7214 ,  A61B2562/028

Abstract: A micro analyte sensor includes a substrate, which includes an internal part and an external part; a first electrode group and a second electrode group, located on the surface of the internal part, each electrode group including at least one working electrode and at least one additional electrode. The external part is provided with pins corresponding to each electrode, the pins are respectively electrically connected with the working electrode and the additional electrode through wires. The first electrode group detects the analyte at the first frequency and provides the first detection signal, and the second electrode group detects the analyte at the second frequency and provides the redundant detection signal, and the first frequency is not less than the second frequency.

公开(公告)号：US12097072B2

公开(公告)日：2024-09-24

申请号：US17223571

申请日：2021-04-06

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Jeremy Stigall ,  Princeton Saroha

IPC: A61B8/00 ,  A61B8/12

CPC classification number: A61B8/12 ,  A61B8/445 ,  A61B8/4488 ,  A61B8/4494 ,  A61B2562/028 ,  A61B2562/12 ,  A61B2562/227

Abstract: Intravascular ultrasound (IVUS) imaging devices, systems, and methods are provided. Embodiments of the present disclosure provide intravascular ultrasound (IVUS) devices with robust, four-wire electrical interconnects. In some embodiments, an intravascular ultrasound (IVUS) device is provided. The IVUS device comprises: a catheter body; an ultrasound assembly coupled to a distal portion of the catheter body; and four conductors extending along a length of the catheter body, wherein a distal section of each of the four conductors has a flattened profile and wherein the flattened distal section of each of the four conductors is electrically coupled to a respective electrical contact of the ultrasound assembly. The ultrasound assembly can be a phased-array ultrasound assembly or a rotational ultrasound assembly.

公开(公告)号：US12097025B2

公开(公告)日：2024-09-24

申请号：US16945239

申请日：2020-07-31

Applicant: BIONIME CORPORATION

Inventor： Chun-Mu Huang ,  Chieh-Hsing Chen ,  Heng-Chia Chang ,  Chi-Hao Chen ,  Chien-Chung Chen

IPC: A61B5/145 ,  A61B5/1473 ,  A61B5/1486

CPC classification number: A61B5/14503 ,  A61B5/1451 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14735 ,  A61B5/14865 ,  A61B2560/0223 ,  A61B2560/0468 ,  A61B2562/0215 ,  A61B2562/028 ,  A61B2562/125 ,  A61B2562/16

Abstract: The present invention provides a measuring method for prolonging a usage lifetime of a biosensor to measure a physiological signal representative of a physiological parameter associated with an analyte in a biofluid. The biosensor includes two working electrodes at least partially covered by a chemical reagent and two counter electrodes having silver and a silver halide, and each silver halide has an initial amount. The measuring method includes cyclic steps of: applying a measurement voltage to drive one of the two working electrodes at a measurement period to measure the physiological signal, thereby obtaining the physiological parameter, wherein the silver halide of one of the two working electrodes is consumed by a consumption amount; stopping applying the measurement voltage; and applying a replenishment voltage to drive the consumed counter electrode at a replenishment period to replenish the silver halide of a recharge amount to the consumed counter electrode, wherein: whenever the physiological parameter is obtained, a guarding value of a sum of the recharge amount and the initial amount subtracting the consumption amount is controlled within a range of the initial amount plus or minus a specific value.

公开(公告)号：US12089938B2

公开(公告)日：2024-09-17

申请号：US17267908

申请日：2019-08-01

Applicant: Verily Life Sciences LLC

Inventor： Annapurna Karicherla ,  Bejamin K. Yaffe ,  Celine Liong ,  Kimberly Kam

IPC: A61B5/263 ,  A61B5/294 ,  A61B5/388 ,  A61N1/05

CPC classification number: A61B5/263 ,  A61B5/388 ,  A61N1/05 ,  A61B5/294 ,  A61B2562/0209 ,  A61B2562/028 ,  A61B2562/0285 ,  A61B2562/04 ,  A61B2562/125 ,  A61N1/0556

Abstract: Embodiments relate to implantable-lead devices that include one or more materials with altered morphology and methods for making and using the same. Specifically, the morphology of electrodes and/or one or more other implant-device materials can be textured to include micro- and/or nanoscale topographical features, which can reduce in vivo fibrotic response and thereby improve signal-to-noise ratios and short-term extractability of the devices.

公开(公告)号：US12082935B2

公开(公告)日：2024-09-10

申请号：US17253466

申请日：2019-06-20

Applicant: Nypro Inc.

Inventor： Yusuf Abu Tayeb Bhagat ,  Patrick John Verdon ,  Daniel Robert Parsons ,  Ralph Hugeneck ,  Mark Edward Sussman ,  David Donald Logan ,  Sai Guruva Reddy Avuthu ,  Girish Satish Wable

IPC: A61B5/28 ,  A61B5/00 ,  A61B5/11 ,  A61B5/257 ,  A61B5/265

CPC classification number: A61B5/28 ,  A61B5/0006 ,  A61B5/1117 ,  A61B5/257 ,  A61B5/265 ,  A61B5/6833 ,  A61B2562/0219 ,  A61B2562/028

Abstract: A disposable vital signs monitor patch includes hydrogel based conductive adhesives which contacts skin. A medical tape bonds to the skin and has printed silver-silver chloride electrodes. The hydrogel based conductive adhesives interact between the skin and the printed silver-silver chloride electrodes. A double-sided medical tape bonds to the medical tape. A printed circuit board assembly (PCBA) includes a vital signs sensor, a flexible battery, a light emitting device (LED), connects to the printed silver-silver chloride electrodes, and bonds to the double-sided medical tape. A polyethylene foam includes a cut-out for the flexible the LED. The PCBA bonds to the polyethylene foam layer. A plunger operates within a cut-out on the polyethylene foam layer. An acrylic adhesive transfer tape bonds to the acrylic adhesive transfer tape. The medical tape, the double-sided medical tape, the polyethylene foam, and the acrylic adhesive transfer tape bond to seal against environmental exposure.

公开(公告)号：US20240277218A1

公开(公告)日：2024-08-22

申请号：US18629779

申请日：2024-04-08

Applicant: Alcon Inc.

Inventor： Paul R. HALLEN

IPC: A61B1/07 ,  A61B1/00 ,  A61B1/06 ,  A61F9/007

CPC classification number: A61B1/07 ,  A61B1/00045 ,  A61B1/0638 ,  A61B1/0661 ,  A61F9/00736 ,  A61B2562/0219 ,  A61B2562/028

Abstract: An ophthalmic endoscope includes a surgical handpiece and an endoscopic tip coupled to the surgical handpiece. A probe extends from the endoscopic tip. An illumination source is disposed in the surgical handpiece. A plurality of illumination fibers are disposed in the probe. The plurality of illumination fibers include a first end coupled to the illumination source and a second end that projects illumination outwardly from the probe. A wavelength of illumination supplied by the illumination source is adjustable between visible light and near-infrared light.

公开(公告)号：US12066620B2

公开(公告)日：2024-08-20

申请号：US16979083

申请日：2019-03-08

Applicant: Scinvivo B.V.

Inventor： Hendrikus Wilhelmus Leonardus Antonius Maria Van Lierop ,  Maaike De Jong ,  Geert Claassen

IPC: G02B26/08 ,  A61B5/00 ,  G01B9/02 ,  G01B9/02091

CPC classification number: G02B26/0841 ,  A61B5/0066 ,  G01B9/0205 ,  G01B9/02091 ,  A61B2562/0242 ,  A61B2562/028 ,  A61B2562/12

Abstract: A forward looking MEMS based OCT probe (50) is provided that comprises an elongate probe housing (51) having at a first end a probe interface (54) for an optic fibre (56), and at a second opposite end a viewing window (58). The probe housing accommodates a MEMS mirror (10) for sweeping a hght beam (60) through the viewing window and for reflecting light received through the viewing window towards the probe interface, wherein a rotation axis (18) of the MEMS mirror extends transverse to a longitudinal axis (62) defined by the probe housing. The MEMS mirror (10) has a stator (12), a rotor (14), and an actuator (16) with at least one pair of mutually interdigitated comb elements including at least a first comb element fixed to the stator defining a reference plane and at least a second comb element fixed to the rotor and that is further coupled at mutually opposite sides via a respective torsion beam (20A, 20B) to the stator. The rotor has a rotor body (14RB) and a rotor support (14RS), fixed at a first face of the rotor body, that keeps the rotor body at a distance from the stator within said rotation range, the rotor body having a mirror surface (14MS) at a second face opposite the first face, the MEMS mirror comprising the stator (12) and the rotor support (14RS) at mutually opposite sides of the reference plane (RP).

公开(公告)号：US20240268789A1

公开(公告)日：2024-08-15

申请号：US18168455

申请日：2023-02-13

Applicant: SoundCath, Inc.

Inventor： Donald Masters ,  Jesus Andres Lopez ,  Eric Stoppenhagen

IPC: A61B8/00 ,  A61B8/08 ,  A61B8/12

CPC classification number: A61B8/4494 ,  A61B8/0883 ,  A61B8/12 ,  A61B8/4254 ,  A61B8/445 ,  A61B2562/028

Abstract: An ultrasonic imaging system is disclosed. The ultrasonic imaging system comprises an Intracardiac echocardiographic (ICE) catheter and a transducer ring. A steerable sheath integrated with a built-in forward looking transducer and the transducer ring positioned at a distal end of the steerable sheath. The transducer ring comprises a MEMS based pMUT array arranged over a substrate. A catheter shaft houses a lumen to allow a passage of a puncture needle and an electronic flex cable in communication with at least one signal trace, configured to: direct the MEMS based pMUT array, via the at least one signal trace, to transmit and receive, ultrasound beams; receive at least one signal from the MEMS based pMUT array based on transmitting and receiving at least one ultrasound beam; and construct at least one image of at least a portion of the heart based on the at least one signal.

公开(公告)号：US20240197253A1

公开(公告)日：2024-06-20

申请号：US18287536

申请日：2021-12-16

Applicant: ALBITI INC.

Inventor： JUN YOUNG AHN ,  Eun Hee JANG

IPC: A61B5/00 ,  A61B5/145 ,  C23C14/02 ,  C23C14/04 ,  C23C14/20 ,  C25D3/50 ,  C25D7/00

CPC classification number: A61B5/685 ,  A61B5/14532 ,  C23C14/025 ,  C23C14/042 ,  C23C14/205 ,  C25D3/50 ,  C25D7/00 ,  A61B2562/028 ,  A61B2562/125

Abstract: Disclosed is a microneedle biosensor and a manufacturing method for same, the microneedle biosensor comprising: a working electrode that comprises a circular thin-film first base, a plurality of microneedles protruding vertically upwards from the first base, and first wiring extending from one side of the circumference of the first base; a counter electrode that comprises a second base which is a three-quarter circle strip thin-film that is concentric with the first base and separated by a set distance from the circumference of the first base, a plurality of microneedles protruding vertically upwards from the second base, and second wiring extending from one side of the second base so as to be disposed on a level with the first wiring; and a reference electrode that comprises a third base which is a quarter circle strip thin-film that is separated by a set difference from the other side of the second base, is concentric with the first base and is separated by a set distance from the circumference of the first base, a plurality of microneedles protruding vertically upwards from the third base, and third wiring extending from one side of the third base.