公开(公告)号：US20130281502A1

公开(公告)日：2013-10-24

申请号：US13914617

申请日：2013-06-10

申请人： Dennis Sgroi ,  Mark G. Erlander ,  Yi Zhang ,  Catherine A. Schnabel

发明人： Dennis Sgroi ,  Mark G. Erlander ,  Yi Zhang ,  Catherine A. Schnabel

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/118 ,  C12Q2600/158

摘要： The disclosure includes the identification and use of gene expression profiles, or patterns, with clinical relevance to extended treatment and cancer-free survival in a patient. In particular, the disclosure includes the identities of genes that are expressed in correlation with benefit in a switch in endocrine therapy used to treat a patient. The levels of gene expression are disclosed as a molecular index for predicting clinical outcome, and so prognosis, for the patient. The disclosure further includes methods for predicting cancer recurrence, and/or predicting occurrence of metastatic cancer, after initial treatment with an anti-estrogen agent. The disclosure further includes methods for determining or selecting the treatment of a subject based upon the likelihood of life expectancy, cancer recurrence, and/or cancer metastasis.

摘要翻译： 该公开内容包括鉴定和使用基因表达谱或模式，其与患者中延长的治疗和无癌生存具有临床相关性。 具体地，本公开包括与用于治疗患者的内分泌治疗的转换中的益处相关表达的基因的身份。 公开了基因表达水平作为预测临床结果的分子指标，并为患者预后。 本发明还包括在用抗雌激素剂初次治疗后预测癌症复发和/或预测转移性癌症的发生的方法。 本公开还包括基于预期寿命，癌症复发和/或癌症转移的可能性来确定或选择受试者的治疗的方法。

公开(公告)号：US20130226011A1

公开(公告)日：2013-08-29

申请号：US13858631

申请日：2013-04-08

申请人： Yi Zhang ,  Jeffrey E. Stahmann

发明人： Yi Zhang ,  Jeffrey E. Stahmann

IPC分类号： A61B5/0205 ,  A61B5/00 ,  A61B5/021

CPC分类号： A61B5/746 ,  A61B5/0031 ,  A61B5/0205 ,  A61B5/021 ,  A61B5/024 ,  A61B5/053 ,  A61B5/0816 ,  A61B5/0826 ,  A61B5/085 ,  A61B5/091 ,  A61B5/1036 ,  A61B5/1118 ,  A61B5/16 ,  A61B5/165 ,  A61B5/4836 ,  A61B5/4878 ,  A61B5/686 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/7435 ,  A61B5/7475 ,  A61B7/02 ,  G06F19/00

摘要： This document discusses, among other things, receiving a user selection of a heart failure symptom, receiving a user selection of an abnormal psychological condition, receiving information about a physiological patient status parameter, and determining a heart failure status using the received information.

摘要翻译： 本文件尤其涉及接收用户选择的心力衰竭症状，接收用户选择异常心理状况，接收有关生理性患者状态参数的信息，以及使用接收到的信息来确定心力衰竭状态。

公开(公告)号：US08486662B2

公开(公告)日：2013-07-16

申请号：US13288260

申请日：2011-11-03

申请人： Richard Evan Gelinas ,  Mitra Choudhury Singhal ,  Yi Zhang ,  Andrew George Popplewell ,  Ralph Adams

发明人： Richard Evan Gelinas ,  Mitra Choudhury Singhal ,  Yi Zhang ,  Andrew George Popplewell ,  Ralph Adams

IPC分类号： C12N15/09 ,  C12P21/08

CPC分类号： A61K39/3955 ,  A61K2039/505 ,  C07K16/248 ,  C07K2316/96 ,  C07K2317/24 ,  C07K2317/34 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/92 ,  C12N15/11

摘要： The invention relates to antibody molecules having specificity for antigenic determinants of IL-6, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.

摘要翻译： 本发明涉及对IL-6的抗原决定簇具有特异性的抗体分子，抗体分子的治疗用途以及产生所述抗体分子的方法。

公开(公告)号：US20130178204A1

公开(公告)日：2013-07-11

申请号：US13643607

申请日：2010-08-13

申请人： Yi Zhang ,  Weihua Zhou ,  Richard Waldhauser

发明人： Yi Zhang ,  Weihua Zhou ,  Richard Waldhauser

IPC分类号： H04W24/02

CPC分类号： H04W24/02 ,  H04W36/0083 ,  H04W48/16 ,  H04W76/18

摘要： A method of determining a radio link failure associated with a handover of a user equipment from a source access node to a target access node includes acquiring a first information about a time associated with the user equipment communicating with an access node for establishing a connection associated with the handover and a second information indicating the access node with which the user equipment communicates for establishing a connection subsequent to the radio link failure, and determining the radio link failure based on the acquired first and/or second information.

摘要翻译： 确定与用户设备从源接入节点到目标接入节点的切换相关联的无线电链路故障的方法包括获取与用户设备相关联的与接入节点通信的时间的第一信息，用于建立与 所述切换以及指示所述接入节点的第二信息，所述接入节点与所述用户设备通信用于在所述无线电链路故障之后建立连接，以及基于所获取的第一和/或第二信息来确定所述无线电链路故障。

公开(公告)号：US20130100635A1

公开(公告)日：2013-04-25

申请号：US13807271

申请日：2011-06-28

申请人： Li Xu ,  Yi Zhang

发明人： Li Xu ,  Yi Zhang

IPC分类号： F21V9/00 ,  F21V9/14 ,  F21V29/00

CPC分类号： F21V9/00 ,  F21K9/64 ,  F21V9/14 ,  F21V9/30 ,  F21V29/502 ,  F21V29/70 ,  F21Y2115/10 ,  F21Y2115/30

摘要： High lumen output and brightness illumination modules using an excitation light source and wavelength conversion part with multi-channel heat dissipation are disclosed. The exciting light source is a light emitting diode or a laser diode emitting in the UV and/or blue region. The luminescent material in the wavelength conversion part absorbs the excitation light and emit longer wavelength light. The enhancement approaches for brightness and polarization is disclosed.

摘要翻译： 公开了使用具有多通道散热的激发光源和波长转换部分的高流明输出和亮度照明模块。 激发光源是在UV和/或蓝色区域中发射的发光二极管或激光二极管。 波长转换部中的发光材料吸收激发光并发射较长波长的光。 公开了亮度和极化的增强方法。

公开(公告)号：US20130083571A1

公开(公告)日：2013-04-04

申请号：US13466739

申请日：2012-05-08

申请人： Boyu Pu ,  Jinping Zhou ,  Yi Zhang ,  Wei Chen

发明人： Boyu Pu ,  Jinping Zhou ,  Yi Zhang ,  Wei Chen

IPC分类号： H02M1/12

CPC分类号： H02M1/126 ,  H02M7/487 ,  H02M2007/2195 ,  H02P27/06 ,  Y02B70/1408 ,  Y02P80/112

摘要： A three-phase rectification module, the system thereof and harmonic suppression method are provided. The module includes a LCL filter unit, a three-phase uni-directional rectification unit coupled to the LCL filter unit, and a rectifier control unit for controlling power factor of three-phase AC power source and DC output voltage of the three-phase uni-directional rectification unit. A commutation diode is serially connected on the bridge-arm of each set of uni-directional rectification branch which is included in the three-phase uni-directional rectification unit, making it function as current uni-direction. Herein, the power factor of the three-phase AC power source is matched with the parameters of the LCL filter unit, such that the absolute value of the phase difference between AC input voltage and current of the three-phase uni-directional rectification unit is close or equal to a preset threshold.

摘要翻译： 提供三相整流模块，其系统和谐波抑制方法。 该模块包括LCL滤波器单元，耦合到LCL滤波器单元的三相单向整流单元，以及用于控制三相交流电源的功率因数和三相单相直流输出电压的整流器控制单元 双向整流单元。 整流二极管串联连接在三相单向整流单元中的每组单向整流分支的桥臂上，使其作为当前的单向功能。 这里，三相交流电源的功率因数与LCL滤波器单元的参数相匹配，使得三相单向整流单元的交流输入电压与电流之间的相位差的绝对值为 接近或等于预设阈值。

公开(公告)号：US08406375B2

公开(公告)日：2013-03-26

申请号：US13142712

申请日：2010-12-28

申请人： Yigang Yang ,  Tiezhu Li ,  Qinjiar Zhang ,  Yi Zhang ,  Yingkang Jin ,  Qinghao Chen ,  Yuanjing Li ,  Yinong Liu

发明人： Yigang Yang ,  Tiezhu Li ,  Qinjiar Zhang ,  Yi Zhang ,  Yingkang Jin ,  Qinghao Chen ,  Yuanjing Li ,  Yinong Liu

IPC分类号： G01N23/201

CPC分类号： G01V5/0016 ,  G01N23/046 ,  G01N23/05 ,  G01N2223/419 ,  G01V5/0025

摘要： The present invention discloses an article inspection device, comprising: an x-ray machine, a collimation unit, a transmission detector array and a scattering detector array. The scattering detector array comprising a plurality of same scattering detector modules arranged in a matrix of i-rows and j-columns. A transmission cross section of the article transmitted by the x-rays is divided into a plurality of same sub-regions arranged in a matrix of i-rows and j-columns. The plurality of scattering detector modules arranged in i-rows and j-columns correspond to the plurality of sub-regions arranged in i-rows and j-columns one by one for detecting pair production effect annihilation photons and Compton-effect scattering photons from the respective sub-regions. Obtaining atomic numbers of the respective sub-regions based on a ratio of the pair production effect annihilation photon count to the Compton-effect scattering photon count, so as to form a three-dimensional image of the article. In addition, the present invention further discloses an article inspection method.

摘要翻译： 本发明公开了一种物品检查装置，包括：x射线机，准直单元，透射检测器阵列和散射检测器阵列。 散射检测器阵列包括以i行和j列的矩阵排列的多个相同的散射检测器模块。 通过X射线透射的物品的透射截面被划分成以i行和j列的矩阵排列的多个相同的子区域。 布置在i行和j列中的多个散射检测器模块对应于一排一列地排列在i行和j列中的多个子区域，用于检测来自该对象的生成效应湮灭光子和康普顿效应散射光子 各分区域。 基于对生产效应湮灭光子计数与康普顿效应散射光子计数的比率，获得各个子区域的原子序数，以形成物品的三维图像。 此外，本发明还公开了一种物品检查方法。

公开(公告)号：US08391377B2

公开(公告)日：2013-03-05

申请号：US13026914

申请日：2011-02-14

申请人： Yuanrong Zhu ,  Jianjun Chen ,  Zhubiao He ,  Jianfeng Wu ,  Ming Xu ,  Yi Zhang ,  Yuntao Zhu ,  Pinghua He

发明人： Yuanrong Zhu ,  Jianjun Chen ,  Zhubiao He ,  Jianfeng Wu ,  Ming Xu ,  Yi Zhang ,  Yuntao Zhu ,  Pinghua He

IPC分类号： H04L27/00

CPC分类号： H01Q1/246 ,  H01Q3/267 ,  H01Q3/34 ,  H04B7/0617 ,  H04B7/0842 ,  H04B17/11 ,  H04B17/21

摘要： An active antenna, a base station, a method for refreshing the amplitude and phase, and a signal processing method are disclosed to simplify the structure of a phase shifter and guarantee the reliability of the phase shifter. The active antenna or the base station includes an antenna dipole array, a transceiver array, a digital processing unit (DPU), and a transceiving calibration unit. During signal reception, the transceiver demodulates a radio frequency (RF) signal of the antenna dipole into an IQ analog signal, and outputs the IQ analog signal to the DPU; the DPU converts the demodulated IQ analog signal into an IQ digital signal, and performs digital beam forming (DBF) on the IQ digital signal according to the transceiving calibration unit; during signal transmission, the transceiver modulates the IQ analog signal of the DPU into an RF signal, and outputs the RF signal to the antenna dipole; the DPU converts a signal of a base band unit (BBU) into an IQ digital signal in serial/parallel (S/P) mode, and performs DBF on the IQ digital signal according to the transceiving calibration unit.

摘要翻译： 公开了有源天线，基站，振幅和相位刷新的方法以及信号处理方法，以简化移相器的结构并保证移相器的可靠性。 有源天线或基站包括天线偶极子阵列，收发器阵列，数字处理单元（DPU）和收发校准单元。 在信号接收期间，收发器将天线偶极子的射频（RF）信号解调为IQ模拟信号，并将IQ模拟信号输出到DPU; DPU将解调的IQ模拟信号转换为IQ数字信号，并根据收发校准单元对IQ数字信号进行数字波束形成（DBF）; 在信号传输期间，收发器将DPU的IQ模拟信号调制成RF信号，并将RF信号输出到天线偶极子; DPU将基带单元（BBU）的信号以串行/并行（S / P）模式转换为IQ数字信号，并根据收发校准单元对IQ数字信号执行DBF。

公开(公告)号：US08383759B2

公开(公告)日：2013-02-26

申请号：US13429954

申请日：2012-03-26

申请人： Shinji Ohtomo ,  Tadashi Fukunaka ,  Yi Zhang

发明人： Shinji Ohtomo ,  Tadashi Fukunaka ,  Yi Zhang

IPC分类号： C08G63/18 ,  C08G63/52

CPC分类号： C08G63/065 ,  C08G63/785 ,  C08G63/80

摘要： A method is provided for producing a liquid crystal polyester including: (1) polycondensing a mixture of a compound of formula (I) with a compound of formula (II) in a polymerization tank at 260 to 350° C. to form a prepolymer, wherein a ratio of by-products to be distilled off to the theoretical amount of by-products formed when the compound of formula (I) is polycondensed with the compound of formula (II) in a stoichiometric relation is 95% or more; (2) continuously discharging the prepolymer from the polymerization tank in a molten state, solidifying the prepolymer while transferring, and continuously grinding the solidified prepolymer by a grinder provided downstream in a transfer direction to produce prepolymer particles; and (3) heat-treating the prepolymer particles in their solid state under an inert gas atmosphere, thereby subjecting them to solid phase polymerization.

摘要翻译： 提供了一种用于制备液晶聚酯的方法，包括：（1）将式（I）化合物与式（II）化合物的混合物在聚合槽中在260至350℃下缩聚形成预聚物， 其中当所述式（I）化合物与所述式（II）化合物以化学计量关系缩聚时形成的副产物的理论量的比例为95％以上; （2）在熔融状态下连续地从聚合槽中排出预聚物，在转移的同时使预聚物固化，并通过在转印方向下游设置的研磨机连续研磨固化的预聚物，以制备预聚物颗粒; 和（3）在惰性气体气氛下以固态热处理预聚物颗粒，进行固相聚合。

公开(公告)号：US08372012B2

公开(公告)日：2013-02-12

申请号：US12769020

申请日：2010-04-28

申请人： Viktoria Averina ,  Yi Zhang ,  Yousufali Dalal

发明人： Viktoria Averina ,  Yi Zhang ,  Yousufali Dalal

IPC分类号： A61B5/02

CPC分类号： A61B5/0816 ,  A61B5/053 ,  A61B5/411 ,  A61B2562/0219 ,  A61N1/3627 ,  A61N1/36521

摘要： Systems and methods provide for assessing the heart failure status of a patient and, more particularly, to generating a trend parameter based on a distribution of the patient's respiration rate. Systems and methods provide for detecting, using an implantable device or a patient-external device, patient respiration and computing a respiration rate based on the detected patient respiration. A distribution of the respiration rate is calculated, and a trend parameter based on the respiration rate distribution is generated. The trend parameter is indicative of a patient's heart failure status. An output signal indicative of the patient's heart failure status may be generated based on the trend parameter.

摘要翻译： 系统和方法提供用于评估患者的心力衰竭状态，更具体地，用于基于患者的呼吸速率的分布来生成趋势参数。 系统和方法提供用于基于检测到的患者呼吸来检测，使用可植入装置或患者外部装置进行患者呼吸并计算呼吸速率。 计算呼吸率的分布，并生成基于呼吸率分布的趋势参数。 趋势参数表示患者的心力衰竭状态。 可以基于趋势参数生成表示患者心力衰竭状态的输出信号。