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公开(公告)号：US20070155959A1
公开(公告)日：2007-07-05
申请号：US11669397
申请日：2007-01-31
申请人： Gerald Sigler , Raymond Hui , Ina Deras , Richard Root , Mitali Ghoshal , Erasmus Huber , Herbert Von Der Eltz , Sigrun Metz , Peter Kern
发明人： Gerald Sigler , Raymond Hui , Ina Deras , Richard Root , Mitali Ghoshal , Erasmus Huber , Herbert Von Der Eltz , Sigrun Metz , Peter Kern
IPC分类号： C07K16/00
摘要： Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for the HIV protease inhibitor saquinavir. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group. Also described are monoclonal antibodies specific for saquinavir having less than 10% cross-reactivity with lopinavir, nelfinavir, amprenavir, ritonavir, and indinavir, and a murine hybridoma producing said antibodies.
摘要翻译： 可用于产生HIV蛋白酶抑制剂的免疫原的活化的半抗原，可用于产生HIV蛋白酶抑制剂的抗体的免疫原，以及可用于HIV蛋白酶抑制剂沙奎那韦的免疫测定的抗体和标记的缀合物。 新型半抗原在中心非末端羟基处具有活化的功能。 还描述了与洛匹那韦，奈非那韦，安仁那韦，利托那韦和茚地那韦具有小于10％交叉反应性的沙奎那韦特异性单克隆抗体，以及产生所述抗体的鼠杂交瘤。
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公开(公告)号：US5251425A
公开(公告)日：1993-10-12
申请号：US851009
申请日：1992-03-11
申请人： Peter Kern
发明人： Peter Kern
摘要： A device for feeding and stuffing envelopes opens the flap (2) of the bottom envelope (3) of a stack (1) with a rotating opener claw (5, 6, 7 ). As soon as the flap is sufficiently open, it is seized by two rotating transport elements (8, 9) and pressed against two conveyor rollers (10, 11). The opener claws (5, 6, 7) and the conveyor elements (8, 9) are disposed on the same shaft (4), but are supported and driven independently of each other. The opener claws are only operated from a coupling (12) when a packing operation is to be carried out. The conveyor elements (8, 9) and the conveyor rollers (10, 11) run continuously. Two pairs of conveyor rollers (17, 18, 19, 20) convey the envelope towards a packing trap (13). As soon as the flap (2) of the envelope (3) is positioned below a hold down roller (21), the latter begins to descend. Simultaneously, the packing trap (13) begins to pivot towards the envelope and the envelope (3) is drawn onto the packing trap (13). The prepared contents (38) of the envelope are conveyed by transport fingers (34) into the packing trap (13) from the opposite side. Transport fingers (34) push the envelope (3) and contents (38) from the packing trap between conveyor belts (43, 44) and out of the enveloping unit.
摘要翻译： 用于进给和填充信封的装置用旋转的开启爪（5,6,7）打开堆叠（1）的底部信封（3）的翼片（2）。 一旦瓣片充分打开，它被两个旋转的运送元件（8,9）扣住并压靠在两个传送辊（10,11）上。 开启爪（5,6,7）和输送元件（8,9）设置在相同的轴（4）上，但彼此独立地被支撑和驱动。 开启器爪只能在进行包装操作时从联轴器（12）进行操作。 输送机元件（8,9）和输送辊（10,11）连续运行。 两对传送辊（17,18,19,20）将信封传送到一个包装捕集器（13）。 一旦封套（3）的挡板（2）位于压紧辊（21）的下方，后者开始下降。 同时，包装捕集器（13）开始朝向信封枢转，并且信封（3）被吸引到包装捕集器（13）上。 信封的准备内容物（38）由运输指状物（34）从相对侧输送到包装捕集器（13）中。 运输手指（34）将信封（3）和内容物（38）从输送带（43,44）之间的包装收集器推出并包出包装单元。
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公开(公告)号：US4829858A
公开(公告)日：1989-05-16
申请号：US214923
申请日：1988-06-09
申请人： Peter Kern , Gerhard Bayer , Johannes Solf
发明人： Peter Kern , Gerhard Bayer , Johannes Solf
摘要： In order to ergonomically optimize the hand side of combination pliers, whose gripping arms in each case form a mouth jaw on their ends and are in operative connection by means of a joint in such a way that in the case of different activities with the pliers the adaptation of the gripping arms to the anatomy and anthropometry of the human hand is retained, it is proposed that the gripping arms face one another elliptically in the plane thereof and that in the vicinity of the coupling surface to the hand the gripping arms have an elliptical cross-section.
摘要翻译： 为了人体工程学地优化组合钳的手边，其夹持臂在每种情况下在其端部形成嘴巴，并且通过接头以这样的方式操作连接，使得在与钳子不同的活动的情况下 保持夹持臂对人的手的解剖学和人体测量的适应性，提出夹持臂在其平面中彼此椭圆形地面对，并且在与手的联接表面附近的夹持臂具有椭圆形 横截面。
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公开(公告)号：US20150011011A1
公开(公告)日：2015-01-08
申请号：US14377188
申请日：2013-02-15
申请人： Peter Kern , Herbert Backes
发明人： Peter Kern , Herbert Backes
IPC分类号： G01N1/28
CPC分类号： G01N1/28 , B01L2200/10 , G01N33/54333 , G01N2446/10 , Y10T436/25
摘要： A method for controlled movement of magnetic carriers in a sample volume for performing immunoassays under weightless or reduced-weight conditions, wherein the magnetic carriers are moved inside the sample volume by means of permanent magnets movably arranged relative to at least one spatial axis of the sample volume.
摘要翻译： 一种用于在无重量或重量不足的条件下进行免疫测定的样品体积中的磁性载体的受控运动的方法，其中所述磁性载体通过相对于所述样品的至少一个空间轴可移动地布置的永久磁体移动到所述样品体积内 卷。
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公开(公告)号：US20130153332A1
公开(公告)日：2013-06-20
申请号：US13579354
申请日：2011-02-05
申请人： Robert Marzilger , Rolf Kolb , Ulrich Kübler , Peter Kern , Steffen Jung , Albert Gollhofer
发明人： Robert Marzilger , Rolf Kolb , Ulrich Kübler , Peter Kern , Steffen Jung , Albert Gollhofer
CPC分类号： A61F5/3784 , A61F5/37 , A61H3/008 , A63B21/15 , A63B21/4009 , A63B26/003 , B64D25/06 , B64G1/60
摘要： The invention relates to a device for fixing a test person on a standing surface, wherein at least one rope is tensioned between a hip belt placed on the test person and a retaining plate arranged below the standing surface.
摘要翻译： 本发明涉及一种用于将测试人员固定在站立表面上的装置，其中至少一根绳索在放置在测试人员的臀部皮带和布置在站立表面下方的保持板之间张紧。
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公开(公告)号：US08453823B2
公开(公告)日：2013-06-04
申请号：US12231749
申请日：2008-09-05
申请人： Peter Kern , Reinhard Buri , Eberhard Knödler
发明人： Peter Kern , Reinhard Buri , Eberhard Knödler
CPC分类号： B65H5/023 , B65H20/06 , B65H2404/261 , B65H2404/264 , B65H2404/561 , B65H2701/1916
摘要： Apparatus is provided for transporting a paper or film discrete object in a machine direction. A top engaging portion contacts a first side of the object and a bottom engaging portion contacts a second side of the object opposite the first side and respectively cooperates with the top engaging portion to grip and move the object in the machine direction. At least one of the top engaging portion or the bottom engaging portion includes a plurality of deflectable elements for engaging the object.
摘要翻译： 提供了用于在机器方向上传送纸或胶片离散物体的装置。 顶部接合部分接触物体的第一侧并且底部接合部分接触与第一侧相对的物体的第二侧，并分别与顶部接合部分配合以沿机器方向夹持和移动物体。 顶部接合部分或底部接合部分中的至少一个包括用于接合物体的多个可偏转元件。
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公开(公告)号：US07482437B2
公开(公告)日：2009-01-27
申请号：US11670467
申请日：2007-02-02
申请人： Gerald F. Sigler , Raymond A. Hui , Ina Deras , Richard Terry Root , Mitali Ghoshal , Erasmus Huber , Herbert W. Von Der Eltz , Sigrun Metz , Peter Kern
发明人： Gerald F. Sigler , Raymond A. Hui , Ina Deras , Richard Terry Root , Mitali Ghoshal , Erasmus Huber , Herbert W. Von Der Eltz , Sigrun Metz , Peter Kern
IPC分类号： C07K17/06 , C07K1/10 , C07K16/00 , C07D403/02 , C07D241/04
摘要： Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for the HIV protease inhibitor saquinavir. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group. Also described are monoclonal antibodies specific for saquinavir having less than 10% cross-reactivity with lopinavir, nelfinavir, amprenavir, ritonavir, and indinavir, and a murine hybridoma producing said antibodies.
摘要翻译： 可用于产生HIV蛋白酶抑制剂的免疫原的活化的半抗原，可用于产生HIV蛋白酶抑制剂的抗体的免疫原，以及可用于HIV蛋白酶抑制剂沙奎那韦的免疫测定的抗体和标记的缀合物。 新型半抗原在中心非末端羟基处具有活化的功能。 还描述了与洛匹那韦，奈非那韦，安仁那韦，利托那韦和茚地那韦具有小于10％交叉反应性的沙奎那韦特异性单克隆抗体，以及产生所述抗体的鼠杂交瘤。
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公开(公告)号：US20070148708A1
公开(公告)日：2007-06-28
申请号：US11669200
申请日：2007-01-31
申请人： Gerald Sigler , Raymond Hui , Ina Deras , Richard Root , Mitali Ghoshal , Erasmus Huber , Herbert Von Der Eltz , Sigrun Metz , Peter Kern
发明人： Gerald Sigler , Raymond Hui , Ina Deras , Richard Root , Mitali Ghoshal , Erasmus Huber , Herbert Von Der Eltz , Sigrun Metz , Peter Kern
摘要： Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for the HIV protease inhibitor saquinavor. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group. Also described are monoclonal antibodies specific for saquinavir having less than 10% cross-reactivity with lopinavir, nelfinavir, amprenavir, ritonavir, and indinavir, and a murine hybridoma producing said antibodies.
摘要翻译： 用于产生HIV蛋白酶抑制剂的免疫原的活化的半抗原，可用于产生HIV蛋白酶抑制剂的抗体的免疫原，以及可用于HIV蛋白酶抑制剂saquinavor免疫测定的抗体和标记的缀合物。 新型半抗原在中心非末端羟基处具有活化的功能。 还描述了与洛匹那韦，奈非那韦，安仁那韦，利托那韦和茚地那韦具有小于10％交叉反应性的沙奎那韦特异性单克隆抗体，以及产生所述抗体的鼠杂交瘤。
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公开(公告)号：US20070141643A1
公开(公告)日：2007-06-21
申请号：US11670467
申请日：2007-02-02
申请人： Gerald Sigler , Raymond Hui , Ina Deras , Richard Root , Mitali Ghoshal , Erasmus Huber , Herbert Von Der Eltz , Sigrun Metz , Peter Kern
发明人： Gerald Sigler , Raymond Hui , Ina Deras , Richard Root , Mitali Ghoshal , Erasmus Huber , Herbert Von Der Eltz , Sigrun Metz , Peter Kern
IPC分类号： G01N33/53 , C07D403/02 , C12N5/06
摘要： Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for the HIV protease inhibitor saquinavir. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group. Also described are monoclonal antibodies specific for saquinavir having less than 10% cross-reactivity with lopinavir, nelfinavir, amprenavir, ritonavir, and indinavir, and a murine hybridoma producing said antibodies.
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公开(公告)号：US20070130088A1
公开(公告)日：2007-06-07
申请号：US11342715
申请日：2006-01-30
申请人： Peter Kern , Scott Fowle , Mike Doe
发明人： Peter Kern , Scott Fowle , Mike Doe
CPC分类号： G06Q30/0603 , G06Q10/10 , G06Q30/0283
摘要： A system and method for assisting a plurality of separate businesses is described. In one variation, the method includes establishing a plurality of customized Internet home pages corresponding to the plurality of separate value-adding businesses, and receiving a purchase order via at least one of the plurality of customized Internet home pages. Based on the purchase order, information is sent to a value-adding business and a request for unfinished goods is sent to at least one supplier of unfinished goods. The supplier provides the unfinished goods to the value-adding business to enable the business to alter the unfinished goods in accordance with the purchase order information.
摘要翻译： 描述了用于辅助多个单独的业务的系统和方法。 在一个实施例中，该方法包括建立与多个单独的增值业务相对应的多个定制互联网主页，以及经由多个定制的因特网主页中的至少一个来接收采购订单。 根据采购订单，将信息发送给增值业务，未完成商品的请求将发送至至少一个未完成商品供应商。 供应商将未完成的货物提供给增值业务，以使业务能够根据采购订单信息更改未完成的货物。
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