公开(公告)号：US20170113051A1

公开(公告)日：2017-04-27

申请号：US14920228

申请日：2015-10-22

Applicant: Medtronic, Inc.

Inventor： Todd J. Sheldon ,  Wade M. Demmer ,  Eric R. Williams

IPC: A61N1/365 ,  A61N1/375

CPC classification number: A61N1/36585 ,  A61B5/1116 ,  A61B5/1121 ,  A61B5/4836 ,  A61N1/36535 ,  A61N1/36542 ,  A61N1/37205 ,  A61N1/3756

Abstract: An implantable rate responsive pacemaker includes a sensor module configured to produce an activity signal correlated to a metabolic demand of a patient and a posture signal correlated to patient posture. The pacemaker further includes a pulse generator configured to generate and deliver pacing pulses to a patient's heart via a pair of electrodes coupled to the pacemaker. A control module is coupled to the pulse generator and the sensor module and is configured to determine a sensor indicated pacing rate from the activity signal, compare the posture signal to verification criteria for confirming an exercising posture of the patient, and withhold an adjustment of a pacing rate to the sensor indicated pacing rate responsive to the verification criteria not being met.

公开(公告)号：US20170113035A1

公开(公告)日：2017-04-27

申请号：US15400095

申请日：2017-01-06

Applicant: Medtronic, Inc.

Inventor： Matthew D. Bonner ,  Todd J. Sheldon ,  Kathryn Hilpisch ,  Noelle C. Neafus ,  Rónán Wood

IPC: A61N1/05 ,  A61N1/362 ,  A61N1/372 ,  A61B17/34

CPC classification number: A61N1/0592 ,  A61B17/3468 ,  A61B2017/00044 ,  A61B2017/00243 ,  A61B2017/22035 ,  A61B2017/2215 ,  A61M25/0026 ,  A61M2025/0004 ,  A61M2025/0039 ,  A61N1/059 ,  A61N1/3624 ,  A61N1/36507 ,  A61N1/372 ,  A61N1/37205 ,  A61N1/3756

Abstract: Delivery tools of interventional medical systems facilitate deployment of relatively compact implantable medical devices that include extensions, for example, cardiac pacing devices that include an extension for atrial sensing, wherein an entirety of the device is contained within the delivery tool while a distal-most portion of the tool is navigated to a target implant site. Once at the implant site, a device fixation member may be exposed out from a distal opening of the tool, for initial deployment, while the extension remains contained within the delivery tool. The tool includes a grasping mechanism, operable, within and without a lumen of the tool, to alternately grip and release the device extension, for example, to position a distal end of the extension after the tool has been withdrawn from over an entirety of the initially deployed device.

公开(公告)号：US20160250478A1

公开(公告)日：2016-09-01

申请号：US14632317

申请日：2015-02-26

Applicant: Medtronic, Inc.

Inventor： Saul E. Greenhut ,  Wade M. Demmer ,  Todd J. Sheldon

IPC: A61N1/365

CPC classification number: A61N1/36514 ,  A61N1/37

Abstract: An implantable pacemaker is configured to sense a cardiac electrical signal received by a pair of electrodes coupled to the pacemaker, start a pacing escape interval to control a time that a pacing pulse is delivered in a heart chamber, and detecting if the sensed cardiac electrical signal is a crosstalk event that is an electrical pulse delivered to the patient by a different device than the implantable pacemaker. The implantable pacemaker withholds restarting the pacing escape interval in response to sensing the cardiac electrical signal based on detecting the sensed cardiac electrical signal as the crosstalk event.

Abstract translation: 可植入心脏起搏器被配置为感测由耦合到起搏器的一对电极接收的心脏电信号，开始起搏逃逸间隔以控制起搏脉冲在心脏室中递送的时间，并且检测是否感测的心脏电信号 是串扰事件，其是通过与可植入起搏器不同的装置传送给患者的电脉冲。 基于检测到感测到的心电信号作为串扰事件，可植入起搏器保留重新开始起搏逃逸间隔以响应感测心电信号。

公开(公告)号：US09375580B2

公开(公告)日：2016-06-28

申请号：US14576539

申请日：2014-12-19

Applicant: Medtronic, Inc.

Inventor： Matthew D. Bonner ,  Saul E. Greenhut ,  Todd J. Sheldon ,  Wade M. Demmer

IPC: A61N1/36 ,  A61N1/368 ,  A61N1/375 ,  A61N1/05 ,  A61N1/365 ,  A61N1/39

CPC classification number: A61N1/3682 ,  A61N1/0573 ,  A61N1/36578 ,  A61N1/3756 ,  A61N1/3987

Abstract: A device includes a signal generator module, a processing module, and a housing. The signal generator module is configured to deliver pacing pulses to an atrium. The processing module is configured to detect a ventricular activation event and determine a length of an interval between the ventricular activation event and a previous atrial event that preceded the ventricular activation event. The processing module is further configured to schedule a time at which to deliver a pacing pulse to the atrium based on the length of the interval and control the signal generator module to deliver the pacing pulse at the scheduled time. The housing is configured for implantation within the atrium. The housing encloses the stimulation generator and the processing module.

Abstract translation: 一种装置包括信号发生器模块，处理模块和壳体。 信号发生器模块被配置为向心房输送起搏脉冲。 处理模块被配置为检测心室激活事件并且确定心室激活事件与心室激活事件之前的先前心房事件之间的间隔的长度。 处理模块还被配置为基于间隔的长度来安排将起搏脉冲传送到心房的时间，并且控制信号发生器模块以在预定的时间传送起搏脉冲。 外壳被配置为在心房内植入。 外壳包围刺激发生器和处理模块。

公开(公告)号：US20160144191A1

公开(公告)日：2016-05-26

申请号：US14552758

申请日：2014-11-25

Applicant: Medtronic, Inc.

Inventor： Todd J. Sheldon ,  Wade M. Demmer ,  Karen J. Kleckner ,  Douglas A. Peterson ,  Paul R. Solheim

IPC: A61N1/365

CPC classification number: A61N1/36542 ,  A61N1/36128 ,  A61N1/36135 ,  A61N1/36585

Abstract: An implantable medical device includes an activity sensor, a pulse generator, and a control module. The control module is configured to determine activity metrics from the activity signal and determine an activity metric value at a predetermined percentile of the activity metrics. The control module sets a lower pacing rate set point based on the activity metric value at the predetermined percentile.

Abstract translation: 可植入医疗装置包括活动传感器，脉冲发生器和控制模块。 控制模块被配置为从活动信号确定活动度量，并且以活动度量的预定百分位数确定活动度量值。 控制模块根据预定百分位数的活动度量值设置较低的起搏速率设定值。

公开(公告)号：US20160144190A1

公开(公告)日：2016-05-26

申请号：US14950952

申请日：2015-11-24

Applicant: Medtronic, Inc.

Inventor： Jian Cao ,  Paul J. DeGroot ,  Todd J. Sheldon

IPC: A61N1/365 ,  A61N1/372 ,  A61N1/37

CPC classification number: A61N1/36514 ,  A61B5/0452 ,  A61B5/0456 ,  A61B5/686 ,  A61B5/7292 ,  A61N1/36585 ,  A61N1/3702 ,  A61N1/37288 ,  A61N1/3756

Abstract: An implantable medical device system includes an extracardiac sensing device and an intracardiac pacemaker. The sensing device senses a P-wave attendant to an atrial depolarization of the heart via housing-based electrodes carried by the sensing device when the sensing device is implanted outside the cardiovascular system and sends a trigger signal to the intracardiac pacemaker in response to sensing the P-wave. The intracardiac pacemaker detects the trigger signal and schedules a ventricular pacing pulse in response to the detected trigger signal.

Abstract translation: 可植入医疗装置系统包括心外感测装置和心内起搏器。 当感测装置被植入在心血管系统外部时，感测装置通过基于感应装置的壳体电极感测心脏去极化的P波，并且响应于感测装置将触发信号发送到心脏起搏器 P波。 心脏起搏器检测触发​​信号并响应于检测到的触发信号调度心室起搏脉冲。

公开(公告)号：US20160015984A1

公开(公告)日：2016-01-21

申请号：US14644878

申请日：2015-03-11

Applicant: Medtronic, Inc.

Inventor： Wade M. Demmer ,  Todd J. Sheldon ,  Saul E. Greenhut ,  James D. Reinke

IPC: A61N1/37 ,  A61N1/362 ,  A61N1/365

CPC classification number: A61N1/3706 ,  A61B5/0402 ,  A61B5/0464 ,  A61B5/686 ,  A61N1/36 ,  A61N1/3622 ,  A61N1/36592 ,  A61N1/37205 ,  A61N1/3756

Abstract: The control module of a first pacemaker included in an implantable medical device system including the first pacemaker and a second pacemaker is configured to set a pacing escape interval in response to a far field pacing pulse sensed by the first pacemaker. The far field pacing pulse is a pacing pulse delivered by the second pacemaker. The pacing escape interval is allowed to continue without restarting the in response to a far field intrinsic event sensed by the first pacemaker during the pacing escape interval. The first pacemaker delivers a cardiac pacing pulse to the heart upon expiration of the pacing escape interval.

Abstract translation: 包括在包括第一起搏器和第二起搏器的可植入医疗装置系统中的第一起搏器的控制模块被配置为响应于由第一起搏器感测到的远场起搏脉冲来设定起搏逃生间隔。 远场起搏脉冲是由第二起搏器提供的起搏脉冲。 在起搏逃逸间隔期间允许响应于第一起搏器感测到的远场固有事件而不重新启动起搏逃生间隔。 第一个起搏器在起搏逃生间隔期满后将心脏起搏脉搏提供给心脏。

公开(公告)号：US20150173655A1

公开(公告)日：2015-06-25

申请号：US14139092

申请日：2013-12-23

Applicant: Medtronic, Inc.

Inventor： Wade M. Demmer ,  Todd J. Sheldon

IPC: A61B5/11 ,  A61N1/365

Abstract: A medical device and associated method evaluate vectors of a multi-dimensional accelerometer by receiving a signal from the accelerometer for each of the vectors and determining a metric from the signal for each of the vectors during a first sensing condition and during a second sensing condition. The difference between the metrics determined for the first sensing condition and the second sensing condition for each of the vectors is determined. One of the vectors is selected, based upon the determined differences, for monitoring the patient.

Abstract translation: 医疗装置和相关联的方法通过从每个矢量接收来自加速度计的信号来评估多维加速度计的矢量，并且在第一感测状态期间和在第二感测条件期间，从针对每个矢量的信号确定度量。 确定针对每个矢量对于第一感测条件确定的度量与第二感测条件之间的差异。 基于确定的差异来选择一个载体用于监测患者。

公开(公告)号：US20150157866A1

公开(公告)日：2015-06-11

申请号：US14256133

申请日：2014-04-18

Applicant: Medtronic, Inc.

Inventor： Wade M. Demmer ,  James D. Reinke ,  Todd J. Sheldon ,  Eric R. Williams

IPC: A61N1/37

CPC classification number: A61N1/3708 ,  A61N1/362 ,  G01R31/3606 ,  G01R31/3648 ,  G01R31/3679 ,  H01M10/48

Abstract: A method and apparatus for determining estimated remaining longevity for an implantable stimulator. The device employs pre-calculated numbers of days for various combinations conditions of device usage parameters to determine remaining device longevity based upon identified actual conditions of device usage and employs the determined longevity to change longevity indicator states in the device. While between longevity state changes, the device the identified conditions of device usage and adjusts the determined longevity if the conditions of use change significantly. The indicator states may correspond to one or more of Recommended Replacement Time (RRT), Elective Replacement Indicator (ERI) or End of Service (EOS).

Abstract translation: 一种用于确定可植入刺激器的估计剩余寿命的方法和装置。 设备使用预先计算的天数，用于设备使用参数的各种组合条件，以基于所识别的设备使用的实际条件来确定剩余设备寿命，并采用确定的寿命来改变设备中的寿命指示符状态。 在寿命状态变化之间，设备识别出设备使用条件并调整确定的使用寿命，如果使用条件发生显着变化。 指标状态可能对应于推荐更换时间（RRT），选择性替换指示（ERI）或服务终止（EOS）中的一个或多个。

公开(公告)号：US08781584B2

公开(公告)日：2014-07-15

申请号：US13790683

申请日：2013-03-08

Applicant: Medtronic, Inc.

Inventor： Wade M. Demmer ,  Greggory R. Herr ,  Supriya Ketkar ,  Karen J. Kleckner ,  Todd J. Sheldon ,  Robert W. Stadler

IPC: A61N1/37

CPC classification number: A61N1/371 ,  A61N1/3686 ,  A61N1/3712

Abstract: Various techniques for facilitating selection of a pacing vector for pacing a chamber of a heart are described. One example method described includes, for each of a plurality of vectors, delivering a pacing pulse to capture a first heart chamber, determining a first time interval between the pacing pulse and a sensed event in a second heart chamber, determining a capture detection window in response to the determined first time interval, and enabling a capture detection module to iteratively decrease a pacing pulse magnitude delivered in the first heart chamber until an event in the second heart chamber is not sensed during the determined capture detection window.

Abstract translation: 描述了用于促进选择用于心脏室的起搏矢量的各种技术。 所描述的一个示例性方法包括：对于多个向量中的每一个，递送起搏脉冲以捕获第一心室，确定起搏脉冲与第二心室中的感测事件之间的第一时间间隔，确定第二心室中的捕获检测窗口 响应于确定的第一时间间隔，并且使得捕获检测模块能够迭代地减少在第一心室中递送的起搏脉冲幅度，直到在确定的捕获检测窗口期间没有感测到在第二心室中的事件。