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公开(公告)号：US20220306703A1
公开(公告)日：2022-09-29
申请号：US17671011
申请日：2022-02-14
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas A. Cerruti , Crystal L. Dart , Leigh H. English , Stanislaw Flasinski , Xiaoran Fu , Victor M. Guzov , Arlene R. Howe , Jay P. Morgenstern , James K. Roberts , Sara A. Salvador , Jinling Wang
IPC: C07K14/325 , C12N15/82
Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
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公开(公告)号：US20200255854A1
公开(公告)日：2020-08-13
申请号：US16805362
申请日：2020-02-28
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Arlene R. Howe , Jennifer L. Lutke , Eric Van Fleet
Abstract: Nucleotide sequences are disclosed encoding novel, insecticidal TIC4747 and related proteins exhibiting Hemipteran and Lepidopteran inhibitory activity, as well as fragments thereof. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing a polynucleotide construct encoding one or more of the toxin proteins within the TIC4747-related protein toxin class.
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公开(公告)号：US10717989B2
公开(公告)日：2020-07-21
申请号：US15846796
申请日：2017-12-19
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Jason S. Milligan , James K. Roberts , Yong Yin
IPC: C12N15/82
Abstract: Pesticidal proteins exhibiting toxic activity against Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran pest species are disclosed, and include, but are not limited to, TIC6280, TIC6281, TIC6282, TIC6283, TIC8808, TIC9480, TIC9257, TIC7106, TIC7017, TIC7107, TIC7108, TIC7109, TIC7110, TIC7111, TIC7589, TIC9258, and TIC9259. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the pesticidal proteins provided. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran, Hemipteran and Thysanopteran infestation are provided which contain recombinant nucleic acid sequences encoding the disclosed pesticidal proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran species pests using the disclosed pesticidal proteins are also provided.
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公开(公告)号：US20200002719A1
公开(公告)日：2020-01-02
申请号：US16573538
申请日：2019-09-17
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas Cerruti , Stanislaw Flasinski , Xiaoran Fu , Arlene R. Howe , Sara Ann Salvador
IPC: C12N15/82 , C07K14/325 , A01N47/08 , A01N63/02
Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
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公开(公告)号：US20180334684A1
公开(公告)日：2018-11-22
申请号：US16047187
申请日：2018-07-27
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas Cerruti , Stanislaw Flasinski , Xiaoran Fu , Arlene R. Howe , Sara Ann Salvador
IPC: C12N15/82 , A01N63/02 , C07K14/325 , A01N47/08
Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
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Patent Agency Ranking
公开(公告)号：US10059959B2
公开(公告)日：2018-08-28
申请号：US14884432
申请日：2015-10-15
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas Cerruti , Stanislaw Flasinski , Xiaoran Fu , Arlene R. Howe , Sara Ann Salvador
Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
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公开(公告)号：US20180208940A1
公开(公告)日：2018-07-26
申请号：US15846796
申请日：2017-12-19
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Jason S. Milligan , James K. Roberts , Yong Yin
IPC: C12N15/82 , C12N15/74 , C07K14/435
Abstract: Pesticidal proteins exhibiting toxic activity against Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran pest species are disclosed, and include, but are not limited to, TIC6280, TIC6281, TIC6282, TIC6283, TIC8808, TIC9480, TIC9257, TIC7106, TIC7017, TIC7107, TIC7108, TIC7109, TIC7110, TIC7111, TIC7589, TIC9258, and TIC9259. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the pesticidal proteins provided. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran, Hemipteran and Thysanopteran infestation are provided which contain recombinant nucleic acid sequences encoding the disclosed pesticidal proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran species pests using the disclosed pesticidal proteins are also provided.
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公开(公告)号：US20180127774A1
公开(公告)日：2018-05-10
申请号：US15849012
申请日：2017-12-20
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas A. Cerruti , Crystal L. Dart , Leigh H. English , Stanislaw Flasinski , Xiaoran Fu , Victor M. Guzov , Arlene R. Howe , Jay P. Morgenstern , James K. Roberts , Sara A. Salvador , Jinling Wang
IPC: C12N15/82
Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
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39.发明申请公开(公告)号：US20160108426A1
公开(公告)日：2016-04-21
申请号：US14884432
申请日：2015-10-15
Applicant: MONSANTO TECHNOLOGY LLC
Inventor： James A. Baum , Thomas Cerruti , Stanislaw Flasinski , Xiaoran Fu , Arlene R. Howe , Sara Ann Salvador
IPC: C12N15/82 , A01N63/02 , A01N47/08 , C07K14/325
CPC classification number: C12N15/8286 , A01N47/08 , A01N63/02 , C07K14/325 , Y02A40/162
Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
Abstract translation: 提供了与天然存在的Cry1Da蛋白毒素相比表现出改进的鳞翅目杀虫活性和增强的鳞翅目光谱的工程化Cry1Da氨基酸序列。 还提供了用于在植物中表达改良蛋白质的多核苷酸序列。 具体实施方案提供了含有昆虫抑制量的工程改造的蛋白质的组合物，以及含有编码一种或多种改进的工程化蛋白质的多核苷酸构建体的重组植物，植物部分和种子。
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公开(公告)号：US12264182B2
公开(公告)日：2025-04-01
申请号：US17671011
申请日：2022-02-14
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , Thomas A. Cerruti , Crystal L. Dart , Leigh H. English , Stanislaw Flasinski , Xiaoran Fu , Victor M. Guzov , Arlene R. Howe , Jay P. Morgenstern , James K. Roberts , Sara A. Salvador , Jinling Wang
IPC: C07K14/325 , C12N15/82 , C12N15/62
Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
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