公开(公告)号：US20250154210A1

公开(公告)日：2025-05-15

申请号：US19030863

申请日：2025-01-17

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Thomas A. Cerruti ,  Crystal L. Dart ,  Leigh H. English ,  Stanislaw Flasinski ,  Xiaoran Fu ,  Victor M. Guzov ,  Arlene R. Howe ,  Jay P. Morgenstern ,  James K. Roberts ,  Sara A. Salvador ,  Jinling Wang

IPC: C07K14/325 ,  C12N15/62 ,  C12N15/82

Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.

公开(公告)号：US12123011B2

公开(公告)日：2024-10-22

申请号：US17938016

申请日：2022-10-04

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine A. Chay ,  Todd A. Ciche ,  Stanislaw Flasinski ,  Arlene R. Howe ,  Jason S. Milligan ,  James K. Roberts ,  Yong Yin

IPC: C12N15/82

CPC classification number: C12N15/8286

Abstract: Pesticidal proteins exhibiting toxic activity against Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran pest species are disclosed, and include, but are not limited to, TIC6280, TIC6281, TIC6282, TIC6283, TIC8808, TIC9480, TIC9257, TIC7106, TIC7017, TIC7107, TIC7108, TIC7109, TIC7110, TIC7111, TIC7589, TIC9258, and TIC9259. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the pesticidal proteins provided. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran, Hemipteran and Thysanopteran infestation are provided which contain recombinant nucleic acid sequences encoding the disclosed pesticidal proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran species pests using the disclosed pesticidal proteins are also provided.

公开(公告)号：US12077770B2

公开(公告)日：2024-09-03

申请号：US17689613

申请日：2022-03-08

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Larry A. Gilbertson ,  David K. Kovalic ,  Thomas J. Larosa ,  Maolong Lu ,  Tichafa R. I. Munyikwa ,  James K. Roberts ,  Wei Wu ,  Bei Zhang

IPC: C12N15/82 ,  A01N63/50 ,  A01N63/60

CPC classification number: C12N15/8286 ,  A01N63/50 ,  A01N63/60 ,  C12N15/8275 ,  C12N15/8279 ,  C12N15/8285 ,  Y02A40/146

Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.

公开(公告)号：US11685930B2

公开(公告)日：2023-06-27

申请号：US16988589

申请日：2020-08-07

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Larry A. Gilbertson ,  David K. Kovalic ,  Thomas J. LaRosa ,  Maolong Lu ,  Tichafa R. I. Munyikwa ,  James K. Roberts ,  Wei Wu ,  Bei Zhang

IPC: C12N15/82 ,  A01N63/50 ,  A01N63/60

CPC classification number: C12N15/8286 ,  A01N63/50 ,  A01N63/60 ,  C12N15/8275 ,  C12N15/8279 ,  C12N15/8285 ,  Y02A40/146 ,  A01N63/50 ,  A01N63/23

Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.

公开(公告)号：US20220306703A1

公开(公告)日：2022-09-29

申请号：US17671011

申请日：2022-02-14

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Thomas A. Cerruti ,  Crystal L. Dart ,  Leigh H. English ,  Stanislaw Flasinski ,  Xiaoran Fu ,  Victor M. Guzov ,  Arlene R. Howe ,  Jay P. Morgenstern ,  James K. Roberts ,  Sara A. Salvador ,  Jinling Wang

IPC: C07K14/325 ,  C12N15/82

Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.

公开(公告)号：US10717989B2

公开(公告)日：2020-07-21

申请号：US15846796

申请日：2017-12-19

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine A. Chay ,  Todd A. Ciche ,  Stanislaw Flasinski ,  Arlene R. Howe ,  Jason S. Milligan ,  James K. Roberts ,  Yong Yin

IPC: C12N15/82

Abstract: Pesticidal proteins exhibiting toxic activity against Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran pest species are disclosed, and include, but are not limited to, TIC6280, TIC6281, TIC6282, TIC6283, TIC8808, TIC9480, TIC9257, TIC7106, TIC7017, TIC7107, TIC7108, TIC7109, TIC7110, TIC7111, TIC7589, TIC9258, and TIC9259. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the pesticidal proteins provided. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran, Hemipteran and Thysanopteran infestation are provided which contain recombinant nucleic acid sequences encoding the disclosed pesticidal proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran species pests using the disclosed pesticidal proteins are also provided.

公开(公告)号：US20180208940A1

公开(公告)日：2018-07-26

申请号：US15846796

申请日：2017-12-19

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine A. Chay ,  Todd A. Ciche ,  Stanislaw Flasinski ,  Arlene R. Howe ,  Jason S. Milligan ,  James K. Roberts ,  Yong Yin

IPC: C12N15/82 ,  C12N15/74 ,  C07K14/435

Abstract: Pesticidal proteins exhibiting toxic activity against Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran pest species are disclosed, and include, but are not limited to, TIC6280, TIC6281, TIC6282, TIC6283, TIC8808, TIC9480, TIC9257, TIC7106, TIC7017, TIC7107, TIC7108, TIC7109, TIC7110, TIC7111, TIC7589, TIC9258, and TIC9259. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the pesticidal proteins provided. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran, Hemipteran and Thysanopteran infestation are provided which contain recombinant nucleic acid sequences encoding the disclosed pesticidal proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran species pests using the disclosed pesticidal proteins are also provided.

公开(公告)号：US20180127774A1

公开(公告)日：2018-05-10

申请号：US15849012

申请日：2017-12-20

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Thomas A. Cerruti ,  Crystal L. Dart ,  Leigh H. English ,  Stanislaw Flasinski ,  Xiaoran Fu ,  Victor M. Guzov ,  Arlene R. Howe ,  Jay P. Morgenstern ,  James K. Roberts ,  Sara A. Salvador ,  Jinling Wang

IPC: C12N15/82

Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.

公开(公告)号：US20180073037A1

公开(公告)日：2018-03-15

申请号：US15709291

申请日：2017-09-19

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： James A. Baum ,  Larry A. Gilbertson ,  David K. Kovalic ,  Thomas J. LaRosa ,  Maolong Lu ,  Tichafa R.I. Munyikwa ,  James K. Roberts ,  Wei Wu ,  Bei Zhang

IPC: C12N15/82 ,  A01N63/02

CPC classification number: C12N15/8286 ,  A01N63/02 ,  C12N15/8275 ,  C12N15/8279 ,  C12N15/8285 ,  Y02A40/162 ,  Y02A40/164

Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.

公开(公告)号：US20170183684A1

公开(公告)日：2017-06-29

申请号：US15373377

申请日：2016-12-08

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Renata Bolognesi ,  Lex Evan Flagel ,  Gerrit Cornelis Segers ,  Larry A. Gilbertson ,  David K. Kovalic ,  Thomas J. LaRosa ,  Maolong Lu ,  Tichafa R. I. Munyikwa ,  James K. Roberts ,  Wei Wu ,  Bei Zhang

IPC: C12N15/82 ,  C12N15/113

CPC classification number: C12N15/8286 ,  A01N57/16 ,  C12N15/113 ,  C12N2310/14 ,  Y02A40/162

Abstract: The present invention provides methods for controlling invertebrate pest infestations, for instance in plants, and related compositions and polynucleotides useful in such methods. More specifically, the present invention provides polynucleotides and methods of use thereof for modifying the expression of genes in an invertebrate pest, for instance through RNA interference.