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公开(公告)号：US20250163110A1
公开(公告)日：2025-05-22
申请号：US19030888
申请日：2025-01-17
Applicant: Monsanto Technology LLC
Inventor： James A. Baum , David J. Bowen , Catherine A. Chay , David J. Chi , William P. Clinton , Crystal L. Dart , Leigh English , Stanislaw Flasinski , Victor M. Guzov , Kevin A. Jarrell , Uma R. Kesanapalli , Thomas M. Malvar , Robert M. McCarroll , Jason S. Milligan , Jay P. Morgenstern , Deborah G. Rucker , Sara A. Salvador , Temple F. Smith , Carlos E. Soto , Collin M. Stultz , Brian M. Turczyk , Ty T. Vaughn , Moritz W.F. von Rechenberg
IPC: C07K14/325 , A01N63/50 , C12N15/82
Abstract: Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.
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公开(公告)号：US20240425872A1
公开(公告)日：2024-12-26
申请号：US18793457
申请日：2024-08-02
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Arlene R. Howe , Kimberly M. Wegener
Abstract: Pesticidal protein exhibiting toxic activity against Lepidopteran and Hemipteran pest species are disclosed, and include, but are not limited to, TIC2199. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the disclosed pesticidal protein. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Hemipteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Lepidopteran and Hemipteran species pests using TIC2199 pesticidal protein are also provided.
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公开(公告)号：US20240124888A1
公开(公告)日：2024-04-18
申请号：US18506855
申请日：2023-11-10
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Uma R. Kesanapalli , Jennifer L. Lutke
IPC: C12N15/82 , A01N37/46 , A01N63/50 , C12Q1/6895
CPC classification number: C12N15/8286 , A01N37/46 , A01N63/50 , C12Q1/6895 , C12Q2600/13 , G01N33/5308
Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL pesticidal proteins are also provided.
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公开(公告)号：US11920145B2
公开(公告)日：2024-03-05
申请号：US17485853
申请日：2021-09-27
Applicant: Monsanto Technology LLC
Inventor： Gregory J. Bean , David J. Bowen , Catherine A. Chay , Arlene R. Howe , Jason S. Milligan , Yong Yin
IPC: C12N15/82 , A01N63/50 , C07K14/195
CPC classification number: C12N15/8286 , A01N63/50 , C07K14/195
Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, TIC11239, TIC11243, TIC11256, TIC4544, TIC4545, TIC6871, TIC7429, TIC7497, TIC7511, TIC7513, TIC7518, TIC7524, TIC7526, TIC7528, TIC7535 and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention. Methods for detecting the presence of the polynucleotides or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC3668-type insecticidal proteins are also provided.
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公开(公告)号：US11492640B2
公开(公告)日：2022-11-08
申请号：US16895921
申请日：2020-06-08
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Stanislaw Flasinski , Arlene R. Howe , Jason S. Milligan , James K. Roberts , Yong Yin
IPC: C12N15/82
Abstract: Pesticidal proteins exhibiting toxic activity against Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran pest species are disclosed, and include, but are not limited to, TIC6280, TIC6281, TIC6282, TIC6283, TIC8808, TIC9480, TIC9257, TIC7106, TIC7017, TIC7107, TIC7108, TIC7109, TIC7110, TIC7111, TIC7589, TIC9258, and TIC9259. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the pesticidal proteins provided. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran, Coleopteran, Hemipteran and Thysanopteran infestation are provided which contain recombinant nucleic acid sequences encoding the disclosed pesticidal proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, Hemipteran, and Thysanopteran species pests using the disclosed pesticidal proteins are also provided.
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Patent Agency Ranking
公开(公告)号：US20220248686A1
公开(公告)日：2022-08-11
申请号：US17584677
申请日：2022-01-26
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Danqi Chen , Todd A. Ciche , Arlene R. Howe , Jennifer L. Lutke , Barbana E. Wiggins , Yuanji Zhang
IPC: A01N63/25 , C12N15/70 , C12Q1/6895 , C07K14/195 , C12N15/82
Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC7941, TIC7941PL_1, TIC7941PL_2, and TIC7941PL_3. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC7941, TIC7941PL_1, TIC7941PL_2, and TIC7941PL_3 pesticidal proteins are also provided. Also disclosed are methods and compositions to improve the insecticidal activity of a pesticidal protein against an insect pest species. Further disclosed are method and compositions to reduce expression of a pesticidal protein in the reproductive tissues of a transgenic plant.
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公开(公告)号：US20220192200A1
公开(公告)日：2022-06-23
申请号：US17559857
申请日：2021-12-22
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Arlene R. Howe , Jason S. Milligan , Christina M. Taylor , Monika R. VanGordon , Kimberly M. Wegener , Brian E. Weiner
Abstract: Pesticidal proteins exhibiting inhibitory, suppressive, and toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC4064 and TIC4064 amino acid sequence variants. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC4064 and TIC4064 amino acid sequence variant pesticidal proteins are also provided.
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公开(公告)号：US20220090122A1
公开(公告)日：2022-03-24
申请号：US17485853
申请日：2021-09-27
Applicant: Monsanto Technology LLC
Inventor： Gregory J. Bean , David J. Bowen , Catherine A. Chay , Arlene R. Howe , Jason S Milligan , Yong Yin
IPC: C12N15/82 , C07K14/195 , A01N63/50
Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, TIC11239, TIC11243, TIC11256, TIC4544, TIC4545, TIC6871, TIC7429, TIC7497, TIC7511, TIC7513, TIC7518, TIC7524, TIC7526, TIC7528, TIC7535 and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention. Methods for detecting the presence of the polynucleotides or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC3668-type insecticidal proteins are also provided.
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公开(公告)号：US20210246464A1
公开(公告)日：2021-08-12
申请号：US17242049
申请日：2021-04-27
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A. Chay , Todd A. Ciche , Uma R. Kesanapalli , Jennifer L. Lutke
IPC: C12N15/82 , C12Q1/6895 , A01N63/50 , A01N37/46 , G01N33/53
Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL pesticidal proteins are also provided.
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公开(公告)号：US20200229445A1
公开(公告)日：2020-07-23
申请号：US16748392
申请日：2020-01-21
Applicant: Monsanto Technology LLC
Inventor： David J. Bowen , Catherine A Chay , Danqi Chen , Todd A. Ciche , Arlene R. Howe , Jennifer L. Lutke , Barbara E. Wiggins , Yuanji Zhang
IPC: A01N63/25 , C12N15/70 , C12N15/82 , C12Q1/6895 , C07K14/195
Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC7941, TIC7941PL_1, TIC7941PL_2, and TIC7941PL_3. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC7941, TIC7941PL_1, TIC7941PL_2, and TIC7941PL_3 pesticidal proteins are also provided. Also disclosed are methods and compositions to improve the insecticidal activity of a pesticidal protein against an insect pest species. Further disclosed are method and compositions to reduce expression of a pesticidal protein in the reproductive tissues of a transgenic plant.
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