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132 条记录 (耗时 0.037 秒)

    Cardiac resynchronization therapy parameter optimization
    31.
    发明授权
    Cardiac resynchronization therapy parameter optimization 有权
    心脏再同步治疗参数优化

    公开(公告)号：US08175703B2

    公开(公告)日：2012-05-08

    申请号：US11338935

    申请日：2006-01-25

    申请人： Yanting Dong ,  Yinghong Yu ,  Jiang Ding ,  Scott A. Meyer ,  Xuan Wei ,  Michael John Stucky

    发明人： Yanting Dong ,  Yinghong Yu ,  Jiang Ding ,  Scott A. Meyer ,  Xuan Wei ,  Michael John Stucky

    IPC分类号： A61N1/362

    CPC分类号： A61N1/3627 ,  A61N1/36585 ,  A61N1/3684

    摘要： Systems and methods involve determination of CRT parameters using a number of CRT optimization processes. Each CRT optimization process attempts to return recommended parameters. The CRT parameters are determined based on the recommended parameters returned by one or more of the CRT optimization processes. The CRT optimization processes may be sequentially implemented and the CRT parameters may be determined based on the recommended parameters returned by a first CRT optimization process to return recommended parameters. The CRT parameters may be determined based on a combination of the recommended parameters returned. The CRT optimization processes implemented may be selected from available CRT optimization processes based on patient conditions.

    摘要翻译： 系统和方法涉及使用多个CRT优化过程来确定CRT参数。 每个CRT优化过程都会尝试返回推荐的参数。 CRT参数根据一个或多个CRT优化过程返回的推荐参数来确定。 可以顺序地实施CRT优化过程，并且可以基于由第一CRT优化过程返回的推荐参数来返回推荐参数来确定CRT参数。 可以基于返回的推荐参数的组合来确定CRT参数。 可以根据患者条件从可用的CRT优化过程中选择实现的CRT优化处理。

    RNFL measurement analysis
    32.
    发明授权
    RNFL measurement analysis 有权
    RNFL测量分析

    公开(公告)号：US08128229B2

    公开(公告)日：2012-03-06

    申请号：US12859727

    申请日：2010-08-19

    申请人： Scott A. Meyer ,  Mary K. Durbin ,  Paul F. Stetson ,  Bagrat Amirbekian

    发明人： Scott A. Meyer ,  Mary K. Durbin ,  Paul F. Stetson ,  Bagrat Amirbekian

    IPC分类号： A61B3/10

    CPC分类号： A61B3/12 ,  A61B3/1241

    摘要： One embodiment of the present invention accounts for individual anatomical variation when evaluating optical nerve fiber measurements. In one aspect, contextual information is used to compensate or correct measurement data. In another aspect, reference coordinates are remapped for improved comparison or visualization. In one embodiment of this latter aspect, the method uses measurements of nerve fiber capacity and maps of nerve fiber retinal service to improve sensitivity and specificity in eye function metrics. In one instance, we use the birefringence of nerve fibers to determine the orientation of the fibers within the RNFL. Orientation of the fibers about the ONH is indicative of the service provided by the fibers and is used to improve the interpretation of thickness measurements of the nerve fiber layer. Normalized nerve fiber measurements about the optic nerve head improve specificity and sensitivity as compared to the standard model. These improvements are a result of partitioning the normative database or modifying the measurement data prior to comparison. Statistics on normalized measurements of nerve fiber bundles also show improvements in specificity and sensitivity.

    摘要翻译： 评估光学神经纤维测量时，本发明的一个实施例解释了个体解剖学变化。 在一个方面，使用上下文信息来补偿或校正测量数据。 在另一方面，重新映射参考坐标以改善比较或可视化。 在后一方面的一个实施例中，该方法使用神经纤维能力的测量和神经纤维视网膜服务的图来提高眼睛功能度量中的灵敏度和特异性。 在一种情况下，我们使用神经纤维的双折射来确定RNFL内纤维的取向。 关于ONH的纤维的取向指示由纤维提供的服务，并且用于改善对神经纤维层的厚度测量的解释。 与标准模型相比，关于视神经头的规范化神经纤维测量提高了特异性和灵敏度。 这些改进是在比较之前划分规范性数据库或修改测量数据的结果。 关于神经纤维束的归一化测量的统计数据也显示出特异性和灵敏度的改善。

    METHOD AND APPARATUS FOR PACING SAFETY MARGIN
    34.
    发明申请
    METHOD AND APPARATUS FOR PACING SAFETY MARGIN 有权
    防治安全隐患的方法和装置

    公开(公告)号：US20110245890A1

    公开(公告)日：2011-10-06

    申请号：US13071680

    申请日：2011-03-25

    申请人： Amy Jean Brisben ,  Shibaji Shome ,  Kenneth N. Hayes ,  Yanting Dong ,  Aaron R. McCabe ,  Scott A. Meyer ,  Kevin John Stalsberg

    发明人： Amy Jean Brisben ,  Shibaji Shome ,  Kenneth N. Hayes ,  Yanting Dong ,  Aaron R. McCabe ,  Scott A. Meyer ,  Kevin John Stalsberg

    IPC分类号： A61N1/08 ,  A61N1/362

    CPC分类号： A61N1/36585 ,  A61N1/3712

    摘要： An apparatus comprises a cardiac signal sensing circuit, a pacing therapy circuit, and a controller circuit. The controller circuit includes a safety margin calculation circuit. The controller circuit initiates delivery of pacing stimulation energy to the heart using a first energy level, changes the energy level by at least one of: a) increasing the energy from the first energy level until detecting that the pacing stimulation energy induces stable capture, or b) reducing the energy from the first energy level until detecting that the stimulation energy fails to induce capture, and continues changing the stimulation energy level until confirming stable capture or the failure of capture. The safety margin calculation circuit calculates a safety margin of pacing stimulation energy using at least one of a determined stability of a parameter associated with evoked response and a determined range of energy levels corresponding to stable capture or intermittent failure of capture.

    摘要翻译： 一种装置包括心脏信号感测电路，起搏治疗电路和控制器电路。 控制器电路包括安全裕度计算电路。 控制器电路使用第一能级开始向心脏传送起搏刺激能量，通过以下至少一种来改变能量水平：a）从第一能量级增加能量直到检测到起搏刺激能量引起稳定的捕获，或 b）减少来自第一能级的能量，直到检测到刺激能量不能诱导捕获，并且继续改变刺激能量水平，直到确认捕获稳定或捕获失败为止。 安全裕度计算电路使用与诱发反应相关联的参数的确定的稳定性以及与捕获的稳定捕获或间歇性故障相对应的能量水平的确定范围中的至少一个来计算起搏刺激能量的安全裕度。

    Arrhythmia discrimination using electrocardiograms sensed from multiple implanted electrodes
    35.
    发明授权
    Arrhythmia discrimination using electrocardiograms sensed from multiple implanted electrodes 有权
    使用从多个植入电极感测的心电图的心律失常辨别

    公开(公告)号：US07917196B2

    公开(公告)日：2011-03-29

    申请号：US11125020

    申请日：2005-05-09

    申请人： Yi Zhang ,  Carlos Alberto Ricci ,  Jeffrey E. Stahmann ,  Aaron R. McCabe ,  Scott A. Meyer ,  Yinghong Yu

    发明人： Yi Zhang ,  Carlos Alberto Ricci ,  Jeffrey E. Stahmann ,  Aaron R. McCabe ,  Scott A. Meyer ,  Yinghong Yu

    IPC分类号： A61B5/0464

    CPC分类号： A61B5/04011 ,  A61B5/7203

    摘要： Cardiac monitoring and/or stimulation methods and systems provide for monitoring, diagnosing, defibrillation and pacing therapies, or a combination of these capabilities, including cardiac systems incorporating or cooperating with neuro-stimulating devices, drug pumps, or other therapies. Embodiments relate generally to implantable medical devices employing automated cardiac activation sequence monitoring and/or tracking for arrhythmia discrimination. Embodiments are directed to devices and methods involving sensing a plurality of composite cardiac signals using a plurality of implantable electrodes. A source separation is performed using the sensed plurality of composite cardiac signals and the separation produces one or more cardiac signal vectors associated with one or more cardiac activation sequences that is indicative of ischemia. A change of the one or more cardiac signal vectors is detected using the one or more cardiac signal vectors. Cardiac arrhythmias are discriminated using the one or more cardiac signal vectors.

    摘要翻译： 心脏监测和/或刺激方法和系统提供监测，诊断，除颤和起搏治疗，或这些能力的组合，包括结合或与神经刺激装置，药物泵或其他疗法组合的心脏系统。 实施例一般涉及使用自动心脏激活序列监测和/或跟踪用于心律失常鉴别的可植入医疗装置。 实施例涉及使用多个可植入电极感测多个复合心脏信号的装置和方法。 使用感测的多个复合心脏信号进行源分离，并且分离产生与指示缺血的一个或多个心脏激活序列相关联的一个或多个心脏信号载体。 使用一个或多个心脏信号矢量检测一个或多个心脏信号矢量的改变。 使用一个或多个心脏信号载体来区分心律失常。

    SYSTEM AND METHOD FOR DECOMPENSATION DETECTION AND TREATMENT BASED ON PATIENT HEMODYNAMICS
    36.
    发明申请
    SYSTEM AND METHOD FOR DECOMPENSATION DETECTION AND TREATMENT BASED ON PATIENT HEMODYNAMICS 有权
    基于患者血液动力学的去除检测和治疗的系统和方法

    公开(公告)号：US20100305649A1

    公开(公告)日：2010-12-02

    申请号：US12787630

    申请日：2010-05-26

    申请人： Barun Maskara ,  Lili Liu ,  Guy Alvarez ,  Scott A. Meyer

    发明人： Barun Maskara ,  Lili Liu ,  Guy Alvarez ,  Scott A. Meyer

    IPC分类号： A61N1/365

    CPC分类号： A61N1/36564

    摘要： A system and method for detecting and treating symptoms of early decompensation utilizing a cardiac rhythm management. The system applies an electrical stimulus to the patient's heart at a first set of pacing parameters including a lower rate limit (LRL) setting, and acquires a coronary venous pressure (CVP) signal from a pressure sensor implanted in a coronary vein of the patient. An average coronary venous end diastolic pressure (CV-EDP) value is calculated from the CVP signal. The system monitors the average CV-EDP value over a predetermined interval, and dynamically adjusts the LRL setting responsive to the detection of a first or a second predetermined event based on the average CV-EDP value.

    摘要翻译： 一种利用心律管理检测和治疗早期失代偿症状的系统和方法。 该系统以包括较低速率限制（LRL）设置在内的第一组起搏参数对患者的心脏施加电刺激，并从植入患者冠状静脉的压力传感器获取冠状静脉压（CVP）信号。 根据CVP信号计算平均冠状静脉舒张末期压（CV-EDP）值。 该系统在预定间隔内监视平均CV-EDP值，并且响应于基于平均CV-EDP值的第一或第二预定事件的检测动态地调整LRL设置。

    METHOD OF BIOIMAGE DATA PROCESSING FOR REVEALING MORE MEANINGFUL ANATOMIC FEATURES OF DISEASED TISSUES
    39.
    发明申请
    METHOD OF BIOIMAGE DATA PROCESSING FOR REVEALING MORE MEANINGFUL ANATOMIC FEATURES OF DISEASED TISSUES 有权
    生物数据处理方法发布疾病组织的更多意义的解剖特征

    公开(公告)号：US20100226542A1

    公开(公告)日：2010-09-09

    申请号：US12709234

    申请日：2010-02-19

    申请人： Matthew J. Everett ,  Scott A. Meyer ,  Paul F. Stetson ,  Yan Zhou

    发明人： Matthew J. Everett ,  Scott A. Meyer ,  Paul F. Stetson ,  Yan Zhou

    IPC分类号： G06K9/00

    CPC分类号： A61B5/0066 ,  G06T7/0014 ,  G06T19/00 ,  G06T2200/24 ,  G06T2207/10101 ,  G06T2207/30041 ,  G06T2210/41

    摘要： The present invention discloses a method for generating elevation maps or images of a tissue layer/boundary with respect to a fitted reference surface, comprising the steps of finding and segmenting a desired tissue layer/boundary; fitting a smooth reference surface to the segmented tissue layer/boundary; calculating elevations of the same or other tissue layer/boundary relative to the fitted reference surface; and generating maps of elevation relative to the fitted surface. The elevation can be displayed in various ways including three-dimensional surface renderings, topographical contour maps, contour maps, en-face color maps, and en-face grayscale maps. The elevation can also be combined and simultaneously displayed with another tissue layer/boundary dependent set of image data to provide additional information for diagnostics.

    摘要翻译： 本发明公开了一种用于产生相对于拟合的参考表面的组织层/边界的仰角图或图像的方法，包括以下步骤：找到并分割所需的组织层/边界; 将平滑的参考表面拟合到分段的组织层/边界; 计算相对于拟合参考表面的相同或其它组织层/边界的高度; 并产生相对于拟合表面的高程图。 高程可以以各种方式显示，包括三维表面效果图，地形轮廓图，轮廓图，面孔颜色图和面对灰度图。 也可以将高程组合并同时显示另一个组织层/边界依赖的图像数据集，以提供用于诊断的附加信息。

    Methods and Systems for Selecting Capture Verification Modes
    40.
    发明申请
    Methods and Systems for Selecting Capture Verification Modes 有权
    用于选择捕获验证模式的方法和系统

    公开(公告)号：US20100131027A1

    公开(公告)日：2010-05-27

    申请号：US12697853

    申请日：2010-02-01

    申请人： Alok Sathaye ,  Scott A. Meyer ,  Derek D. Bohn

    发明人： Alok Sathaye ,  Scott A. Meyer ,  Derek D. Bohn

    IPC分类号： A61N1/08

    CPC分类号： A61N1/3712 ,  A61N1/3627

    摘要： Methods and systems are directed to selecting from a variety of capture verification modes. A plurality of capture verification modes, including a beat by beat capture detection mode and a capture threshold testing mode without intervening beat by beat capture detection is provided. An efficacy of at least one of the capture verification modes is evaluated and, based on the evaluation, a capture verification mode is selected.

    摘要翻译： 方法和系统旨在从各种捕获验证模式中进行选择。 提供了多个拍摄验证模式，包括拍拍拍摄检测模式和拍摄阈值测试模式，而不会通过拍摄捕获检测进行中间拍摄。 评估捕获验证模式中的至少一个的功效，并且基于评估，选择捕获验证模式。