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公开(公告)号：US07985201B2
公开(公告)日：2011-07-26
申请号：US10471692
申请日：2002-03-26
IPC分类号： A61M37/00
CPC分类号： A61M5/20 , A61M5/24 , A61M5/31513 , A61M5/31553 , A61M5/31558 , A61M5/31561 , A61M5/31563 , A61M5/31578 , A61M5/31593 , A61M2005/31518 , A61M2005/3152
摘要： Injection devices are known for the self administration of a medicament by patients in which the medicament is contained within a cartridge located within the injection device. It is a problem that such injection devices should be small enough to fit into a jacket pocket or a hand bag without difficulty. Concurrently, the injection device must be of size that enables a piston or similar used to drive a cartridge bung within the cartridge to be moved both to a maximum dispense position within the cartridge and to be fully withdrawn from the cartridge to allow for replacement of the cartridge. A drive mechanism for an injection device is disclosed comprising a piston member 10, a semi rigid belt 18 connected to the piston member 10, a belt drive means to selectively engage with the semi rigid belt 18 to drive the semi rigid belt 18, and a dose setting mechanism to control the selective engagement of the semi rigid belt in which the semi rigid belt 18 includes a track incorporated therein and the belt drive means comprises a tooth 50 for selective engagement with the track to drive the belt 18 only when there is relative movement between the semi rigid belt 18 and the tooth 50 in a first direction. An injection device comprising such a drive mechanism is also disclosed.
摘要翻译： 注射装置是已知的，其中药物被包含在位于注射装置内的药筒内的患者自身给药。 这样的注射装置应该足够小以难以装入夹克口袋或手提袋中的问题。 同时，注射装置必须具有这样的尺寸，使得用于驱动药筒内的药筒的活塞或类似物能够移动到药筒内的最大分配位置并且完全从药筒中取出，以允许更换 墨盒。 公开了一种用于注射装置的驱动机构，其包括活塞构件10，连接到活塞构件10的半刚性带18，选择性地与半刚性带18接合以驱动半刚性带18的带驱动装置，以及 剂量设定机构，以控制半刚性带的选择性接合，其中半刚性带18包括其中并入的轨道，并且带驱动装置包括齿50，用于选择性地与轨道接合以仅在相对 在半刚性带18和齿50之间沿第一方向的移动。 还公开了一种包括这种驱动机构的注射装置。
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公开(公告)号：US07104973B2
公开(公告)日：2006-09-12
申请号：US11151209
申请日：2005-06-14
CPC分类号： A61M5/24 , A61J1/062 , A61M2205/50 , A61M2205/584 , A61M2205/6045 , A61M2205/6081
摘要： Many of those having diabetes take a combination of slow and fast acting types of insulin. It is important that the different forms of medicament do not become confused and that the patient does not receive the incorrect medicament. In combination a medicament delivery apparatus and a medicament cartridge are provided, the medicament delivery apparatus including at least one switch and the medicament cartridge comprising a cartridge housing within which a medicament is provided, a displaceable piston located internally at one end of the housing and a raised ring of material about an external periphery of the medicament cartridge, the ring of material being of sufficient dimensions, in use, to trip the at least one switch of the medicament delivery apparatus.
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公开(公告)号：US20080228148A1
公开(公告)日：2008-09-18
申请号：US12076333
申请日：2008-03-17
IPC分类号： A61M5/28
CPC分类号： A61M5/24 , A61M2205/583 , A61M2205/6081 , B65D51/002
摘要： Many of those having diabetes take a combination of slow and fast acting types of insulin. It is important that the different forms of medicament do not become confused. To this end, a medicament cartridge is provided comprising a sleeve having a bottleneck providing a flange at a first end, a fluid impermeable membrane secured across the first end by a metal cap beaded beneath the flange, and a displaceable piston located internally of the sleeve towards a second end of the sleeve, a collar located against an external periphery of the cartridge housing beneath the flange and an adaptor top press fit over the cap and the collar, the adaptor top being provided with means to act upon the collar thereby to retain the adaptor top on the sleeve.
摘要翻译： 许多患有糖尿病的患者结合了缓慢和快速作用的胰岛素。 重要的是不同形式的药物不会混淆。 为此，提供一种药剂盒，其包括具有在第一端提供凸缘的瓶颈的套筒，通过凸缘下方的金属帽跨越第一端固定的流体不可渗透膜，以及位于套筒内部的位移活塞 朝向套筒的第二端，套环位于凸缘下方抵靠盒壳体的外周边，并且适配器顶部压配合在盖和套环上方，适配器顶部设置有作用在套环上的装置，从而保持 套筒上的适配器顶部。
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公开(公告)号：US07198615B2
公开(公告)日：2007-04-03
申请号：US10471718
申请日：2002-03-26
CPC分类号： A61M5/3158 , A61M5/24 , A61M5/31513 , A61M5/31553 , A61M5/31563 , A61M5/31593 , A61M2005/31518
摘要： Injection devices are known for the self administration of medicament by patients in which medicament is typically contained within a cartridge located within the injection device. It is a problem that injection devices should be small enough to fit into a jacket pocket or a hand bag without difficulty. Also, the injection device must be of a size that enables a piston or similar used to drive a cartridge bung within the cartridge to be moved both to a maximum dispense position within the cartridge and to be fully withdrawn from the cartridge to allow for replacement of the cartridge. A drive mechanism for an injection device is disclosed in which a second piston (42) is successively moved in relation to a first end of a medicament cartridge (8) containing a medicament selectively to drive a bung (10) into the medicament cartridge (8), the drive mechanism comprising a means (36) defining a passageway (38), a first piston (40) and the second piston (42), in which the passageway (38) has a first end and a second end, the first piston (40) closing the first end of the passageway (38) and a first end of the second piston (42) closing the second end of the passageway (38) to define a chamber in the passageway (38), a non-compressible medium being contained within the chamber such that a first relative movement in a first direction at the first end of the passageway (38) results in a second relative movement in a direction opposite the first direction at the second end of the passageway (38).
摘要翻译： 注射装置是已知的，其中药物通常包含在位于注射装置内的药筒内的患者自身给药。 这是一个注射装置应该足够小以难以装入夹克口袋或手提袋的问题。 而且，注射装置必须具有这样的尺寸，使得活塞或类似物用于驱动药筒内的弹药筒被移动到药筒内的最大分配位置并且完全从药筒中取出，以允许更换 墨盒。 公开了一种用于注射装置的驱动机构，其中第二活塞（42）相对于药物盒（8）的第一端被连续移动，所述药剂盒包含药物，所述药剂盒选择性地将栓（10）驱动到药剂盒（8） ），所述驱动机构包括限定通道（38）的装置（36），第一活塞（40）和所述第二活塞（42），所述通道（38）具有第一端和第二端，所述第一 闭合通道（38）的第一端的活塞（40）和第二活塞（42）的第一端封闭通道（38）的第二端，以限定通道（38）中的室，不可压缩 介质被容纳在腔室内，使得在通道（38）的第一端处的第一方向上的第一相对运动导致在通道（38）的第二端处沿与第一方向相反的方向的第二相对运动。
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公开(公告)号：US07794430B2
公开(公告)日：2010-09-14
申请号：US10471721
申请日：2002-03-26
CPC分类号： A61M5/3158 , A61M5/24 , A61M5/31541 , A61M5/31553 , A61M5/31563 , A61M5/31593 , A61M2005/2414
摘要： Injection devices are known for the self administration of medicament by patients in which the medicaments is typically contained within a cartridge located within the injection device. It is a problem that injection devices should be small enough to fit into a jacket pocket or a hand bag without difficulty. Also, the injection device must be of a size that enables a piston or similar used to drive a cartridge bung within the cartridge to be moved both to a maximum dispense position within the cartridge and to be fully withdrawn from the cartridge to allow for replacement of the cartridge. A drive mechanism for an injection device is disclosed in which a piston (48) is successively moved along the first axis to drive a bung (20) into a medicament cartridge (18), a displacement mechanism comprising a dose setting spindle (30) is disposed along a second axis, the second axis being parallel to the first axis, transmission means connected between the dose setting spindle (30) and the piston (20), and displacement means to displace the dose setting spindle (30) with respect to the medicament cartridge (18), a movement of the displacement means in a first direction causing movement of the dose setting spindle (30) and the piston (20) in the first direction.
摘要翻译： 注射装置是已知的，其中药物通常包含在位于注射装置内的药筒内的患者自身给药。 这是一个注射装置应该足够小以难以装入夹克口袋或手提袋的问题。 而且，注射装置必须具有这样的尺寸，使得活塞或类似物用于驱动药筒内的弹药筒被移动到药筒内的最大分配位置并且完全从药筒中取出，以允许更换 墨盒。 公开了一种用于注射装置的驱动机构，其中活塞（48）沿着第一轴线连续移动以将栓（20）驱动到药剂盒（18）中，包括剂量设定主轴（30）的移位机构是 沿着第二轴线布置，第二轴线平行于第一轴线，连接在剂量设定主轴（30）和活塞（20）之间的传动装置，以及使剂量设定主轴（30）相对于所述活塞 药剂盒（18），位移装置在第一方向上的移动，引起剂量设定主轴（30）和活塞（20）在第一方向上的移动。
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公开(公告)号：US07008405B2
公开(公告)日：2006-03-07
申请号：US10471717
申请日：2002-03-26
CPC分类号： A61M5/3158 , A61M5/24 , A61M5/31513 , A61M5/31553 , A61M5/31563 , A61M5/31593 , A61M2005/31518
摘要： Injection devices are known for the self administration of medicament by patients. The medicament is typically contained within a cartridge located within the injection device. It is a problem that injection devices should be small enough to fit into a jacket pocket or a hand bag without difficulty. Also, the injection device must be of a size that enables a piston or similar used to drive the Cartridge bung within the cartridge to be moved both to a maximum dispense position within the cartridge and to be fully withdrawn from the cartridge to allow for replacement of the cartridge. A drive mechanism for an injecting device is disclosed in which the drive mechanism comprises a displaceable dosing spindle 6, a dial dose means 8, a transmission means 10, and a cable means 12, a piston comprising a plurality of nested piston members 30, 32, 34, displacement of the transmission means 10 causing the cable means 12 to move at least one of one of the nested piston members to drive a cartridge bung 18.
摘要翻译： 已知用于患者自身给药的注射装置。 药物通常包含在位于注射装置内的药筒内。 这是一个注射装置应该足够小以难以装入夹克口袋或手提袋的问题。 而且，注射装置必须具有这样的尺寸，使得活塞或类似物能够驱动药筒内的药筒塞被移动到药筒内的最大分配位置，并且完全从药筒中撤出以允许更换 墨盒。 公开了一种用于注射装置的驱动机构，其中驱动机构包括可移动的定量心轴6，拨号剂量装置8，传动装置10和电缆装置12，包括多个嵌套活塞构件30,32 34，传动装置10的位移，导致缆索装置12移动嵌套的活塞件之一中的至少一个以驱动筒塞18。
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公开(公告)号：US07846146B2
公开(公告)日：2010-12-07
申请号：US12076333
申请日：2008-03-17
IPC分类号： A61B19/00
CPC分类号： A61M5/24 , A61M2205/583 , A61M2205/6081 , B65D51/002
摘要： Many of those having diabetes take a combination of slow and fast acting types of insulin. It is important that the different forms of medicament do not become confused. To this end, a medicament cartridge is provided comprising a sleeve having a bottleneck providing a flange at a first end, a fluid impermeable membrane secured across the first end by a metal cap beaded beneath the flange, and a displaceable piston located internally of the sleeve towards a second end of the sleeve, a collar located against an external periphery of the cartridge housing beneath the flange and an adaptor top press fit over the cap and the collar, the adaptor top being provided with means to act upon the collar thereby to retain the adaptor top on the sleeve.
摘要翻译： 许多患有糖尿病的患者结合了缓慢和快速作用的胰岛素。 重要的是不同形式的药物不会混淆。 为此，提供一种药剂盒，其包括具有在第一端提供凸缘的瓶颈的套筒，通过凸缘下方的金属帽跨越第一端固定的流体不可渗透膜，以及位于套筒内部的位移活塞 朝向套筒的第二端，套环位于凸缘下方抵靠盒壳体的外周边，并且适配器顶部压配合在盖和套环上方，适配器顶部设置有作用在套环上的装置，从而保持 套筒上的适配器顶部。
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公开(公告)号：US07637899B2
公开(公告)日：2009-12-29
申请号：US10307300
申请日：2002-12-02
IPC分类号： A61B19/00
CPC分类号： A61M5/24 , A61M2205/583 , A61M2205/6081 , B65D51/002
摘要： Many of those having diabetes take a combination of slow and fast acting types of insulin. It is important that the different forms of medicament do not become confused. To this end, a medicament cartridge is provided comprising a sleeve having a bottleneck providing a flange at a first end, a fluid impermeable membrane secured across the first end by a metal cap beaded beneath the flange, and a displaceable piston located internally of the sleeve towards a second end of the sleeve, a collar located against an external periphery of the cartridge housing beneath the flange and an adaptor top press fit over the cap and the collar, the adaptor top being provided with means to act upon the collar thereby to retain the adaptor top on the sleeve.
摘要翻译： 许多患有糖尿病的患者结合了缓慢和快速作用的胰岛素。 重要的是不同形式的药物不会混淆。 为此，提供一种药剂盒，其包括具有在第一端提供凸缘的瓶颈的套筒，通过凸缘下方的金属帽跨越第一端固定的流体不可渗透膜，以及位于套筒内部的位移活塞 朝向套筒的第二端，套环位于凸缘下方抵靠盒壳体的外周边，并且适配器顶部压配合在盖和套环上方，适配器顶部设置有作用在套环上的装置，从而保持 套筒上的适配器顶部。
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公开(公告)号：US06945963B2
公开(公告)日：2005-09-20
申请号：US10308011
申请日：2002-12-03
CPC分类号： A61J1/062 , A61M5/24 , A61M2205/6081
摘要： A person having diabetes will often be required to take both slow acting and fast acting forms of insulin. It is important to be able to distinguish readily between medicament cartridges containing different medicaments. The present invention enables a user to distinguish readily between medicament cartridges containing different medicaments. A medicament cartridge and adaptor top assembly is provided, the medicament cartridge comprising a cylinder having a bottleneck provided with a flange at a first end, a fluid impermeable membrane covering the first end, a cap beaded under the flange to retain the fluid impermeable membrane in place, and a piston displaceably located within a second end of the cylinder, and the adaptor top comprising a sleeve having a body portion and a tapered portion, the tapered portion being provided with a smaller diameter end, the smaller diameter end being located beneath the cap.
摘要翻译： 经常需要糖尿病患者服用缓慢作用和快速作用的胰岛素。 能够容易地区分含有不同药物的药剂盒是重要的。 本发明使用户能够容易地区分含有不同药物的药剂盒。 提供了药剂盒和适配器顶部组件，药剂盒包括具有在第一端设有凸缘的瓶颈的圆筒，覆盖第一端的流体不可渗透膜，在凸缘下方串珠的帽，以将流体不可渗透膜保持在 位置以及可移动地位于所述圆筒的第二端内的活塞，并且所述适配器顶部包括具有主体部分和锥形部分的套筒，所述锥形部分设置有较小直径的端部，所述较小直径端部位于所述第二端部的下方 帽。
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公开(公告)号：US06994692B2
公开(公告)日：2006-02-07
申请号：US10471730
申请日：2002-03-26
IPC分类号： A61M1/00
CPC分类号： A61M5/14566 , A61M5/20 , A61M5/24 , A61M5/31511 , A61M5/31553 , A61M5/31558 , A61M5/31575 , A61M5/31578 , A61M2005/14506 , A61M2005/31518
摘要： Injection devices are known for the self administration of a medicament by patients. The medicament is typically contained within a cartridge located within an injection device. It is a problem that injection devices should be small enough to fit into a jacket pocket or a hand bag without difficulty. Concurrently, the injection device must be of a size that enables a piston used to drive a cartridge bung within the cartridge to both to a maximum dispense position within the cartridge and to be fully withdrawn from the cartridge to allow for replacement of the cartridge. A drive mechanism for an injection device is disclosed comprising a piston member (10), a semi rigid belt (12) connected at a first end to the piston member (10), a belt drive means to drive the semi rigid belt (12) and a dose setting mechanism to control the driving of the semi rigid belt (12) in which the belt drive means comprises a first cable means (22) connected at a first end to a second end of the semi rigid belt (12) and at a second end to a first spool (24). An injection device comprising such a drive mechanism is also disclosed.
摘要翻译： 已知用于患者自身给予药物的注射装置。 药物通常包含在位于注射装置内的药筒内。 这是一个注射装置应该足够小以难以装入夹克口袋或手提袋的问题。 同时，注射装置必须具有这样的尺寸，使得活塞能够将筒内的筒塞驱动到筒内的最大分配位置，并且完全从盒中撤出以允许更换筒。 公开了一种用于注射装置的驱动机构，包括活塞构件（10），在第一端连接到活塞构件（10）的半刚性带（12），驱动半刚性带（12）的带驱动装置， 以及用于控制半刚性带（12）的驱动的剂量设定机构，其中带驱动装置包括在第一端连接到半刚性带（12）的第二端的第一缆索装置（22） 第二端到第一线轴（24）。 还公开了一种包括这种驱动机构的注射装置。
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