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公开(公告)号：US07985201B2
公开(公告)日：2011-07-26
申请号：US10471692
申请日：2002-03-26
IPC分类号： A61M37/00
CPC分类号： A61M5/20 , A61M5/24 , A61M5/31513 , A61M5/31553 , A61M5/31558 , A61M5/31561 , A61M5/31563 , A61M5/31578 , A61M5/31593 , A61M2005/31518 , A61M2005/3152
摘要： Injection devices are known for the self administration of a medicament by patients in which the medicament is contained within a cartridge located within the injection device. It is a problem that such injection devices should be small enough to fit into a jacket pocket or a hand bag without difficulty. Concurrently, the injection device must be of size that enables a piston or similar used to drive a cartridge bung within the cartridge to be moved both to a maximum dispense position within the cartridge and to be fully withdrawn from the cartridge to allow for replacement of the cartridge. A drive mechanism for an injection device is disclosed comprising a piston member 10, a semi rigid belt 18 connected to the piston member 10, a belt drive means to selectively engage with the semi rigid belt 18 to drive the semi rigid belt 18, and a dose setting mechanism to control the selective engagement of the semi rigid belt in which the semi rigid belt 18 includes a track incorporated therein and the belt drive means comprises a tooth 50 for selective engagement with the track to drive the belt 18 only when there is relative movement between the semi rigid belt 18 and the tooth 50 in a first direction. An injection device comprising such a drive mechanism is also disclosed.
摘要翻译： 注射装置是已知的，其中药物被包含在位于注射装置内的药筒内的患者自身给药。 这样的注射装置应该足够小以难以装入夹克口袋或手提袋中的问题。 同时，注射装置必须具有这样的尺寸，使得用于驱动药筒内的药筒的活塞或类似物能够移动到药筒内的最大分配位置并且完全从药筒中取出，以允许更换 墨盒。 公开了一种用于注射装置的驱动机构，其包括活塞构件10，连接到活塞构件10的半刚性带18，选择性地与半刚性带18接合以驱动半刚性带18的带驱动装置，以及 剂量设定机构，以控制半刚性带的选择性接合，其中半刚性带18包括其中并入的轨道，并且带驱动装置包括齿50，用于选择性地与轨道接合以仅在相对 在半刚性带18和齿50之间沿第一方向的移动。 还公开了一种包括这种驱动机构的注射装置。
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公开(公告)号：US09345840B2
公开(公告)日：2016-05-24
申请号：US12788665
申请日：2010-05-27
CPC分类号： A61M5/31536 , A61M2005/3154
摘要： A method and system for proving a drug delivery device having a variable dose. The drug delivery device comprising a first tubular member and a second tubular member rotatably coupled to the first tubular member. A maximum stop component is operatively coupled to the first and second tubular member such that the maximum stop component is movable from a first position to a second position. The first position defines a first maximum dose that may be set by a user of said drug delivery device and the second position defines a second maximum dose that may be set by the user of said drug delivery device.
摘要翻译： 用于证明具有可变剂量的药物递送装置的方法和系统。 药物递送装置包括第一管状构件和可旋转地联接到第一管状构件的第二管状构件。 最大限制部件可操作地联接到第一和第二管状部件，使得最大止挡部件可从第一位置移动到第二位置。 第一位置定义可由所述药物递送装置的使用者设定的第一最大剂量，而第二位置限定可由所述药物递送装置的使用者设定的第二最大剂量。
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公开(公告)号：US09205197B2
公开(公告)日：2015-12-08
申请号：US12357899
申请日：2009-01-22
申请人： Christoph Dette , Paul Jansen , Christian Pommereau , Robert Frederick Veasey , Robert Perkins , David Aubrey Plumptre
发明人： Christoph Dette , Paul Jansen , Christian Pommereau , Robert Frederick Veasey , Robert Perkins , David Aubrey Plumptre
CPC分类号： A61M5/31551 , A61M5/002 , A61M5/24 , A61M5/31533 , A61M5/31535 , A61M5/3156 , A61M5/31565 , A61M5/31575 , A61M5/31585 , A61M5/3202 , A61M2005/2407 , A61M2005/3125 , A61M2005/3126 , A61M2205/581 , A61M2205/582 , A61M2205/586
摘要： A method and system for proving a drug delivery device. The device comprises a drug delivery device housing and a medicament contained in the drug delivery device housing. A dose dial sleeve is positioned in the housing and is rotatable to set a non-inverted dose of the medicament contained in the medical delivery device. The non-inverted dose may be increased by turning the dose dial sleeve in a direction towards a user of the drug delivery device. The dose medicament may be decreased by rotating the dose dial sleeve in a direction away from the user.
摘要翻译： 用于证明药物递送装置的方法和系统。 该装置包括药物输送装置壳体和药物输送装置壳体中所含的药物。 剂量拨号套筒定位在壳体中并且可旋转以设置包含在医疗输送装置中的药物的非倒置剂量。 可以通过朝向药物递送装置的使用者的方向转动剂量拨盘套筒来增加非倒置剂量。 可以通过沿远离用户的方向旋转剂量拨盘套筒来减少剂量药物。
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公开(公告)号：US09144649B2
公开(公告)日：2015-09-29
申请号：US14007375
申请日：2012-03-22
CPC分类号： A61M5/31535 , A61M5/24 , A61M5/31525 , A61M5/31528 , A61M5/3155 , A61M5/31551 , A61M5/31555 , A61M5/31585
摘要： A dose setting mechanism for a drug delivery device is provided comprising a dose setting member, a drive member, a clutch, a first clicker and second clicker. The first clutch and a second clutch are designed and adapted to each other such that at any time during operation either the first clutch rotationally couples the dose setting member and the drive member and/or the second clutch rotationally couples the drive member and the first clicker component. Further, the invention refers to an injection device with such a dose setting mechanism.
摘要翻译： 提供了一种用于药物输送装置的剂量设定机构，其包括剂量设定部件，驱动部件，离合器，第一回转器和第二回转器。 第一离合器和第二离合器被设计和适配于彼此，使得在操作期间的任何时候，第一离合器旋转地连接剂量调节构件和驱动构件和/或第二离合器将驱动构件和第一回转器 零件。 此外，本发明涉及具有这种剂量设定机构的注射装置。
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公开(公告)号：US09028454B2
公开(公告)日：2015-05-12
申请号：US12941702
申请日：2010-11-08
CPC分类号： A61M5/24 , A61M5/31528 , A61M5/31533 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31546 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31565 , A61M5/31568 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M5/32 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要： A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.
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公开(公告)号：US08992486B2
公开(公告)日：2015-03-31
申请号：US13909681
申请日：2013-06-04
CPC分类号： A61M5/24 , A61M5/31528 , A61M5/31533 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31546 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31565 , A61M5/31568 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M5/32 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要： A housing for a dispensing apparatus. The housing comprising a main housing and a dose dial sleeve. The dose dial sleeve comprising a helical groove configured to engage a threading provided by the housing. A dose knob is disposed near a proximal end of the dose dial sleeve and a piston rod is provided within the housing. The piston rod is non-rotatable during a dose setting step. A driver comprises an internal threading near a distal portion of the driver and is adapted to engage an external thread of the piston rod. A tubular clutch is located adjacent a distal end of the dose knob and operatively coupled to the dose knob. The dose dial sleeve may extend circumferentially around at least a portion of the tubular clutch.
摘要翻译： 用于分配装置的壳体。 壳体包括主壳体和剂量拨盘套筒。 剂量拨盘套筒包括构造成接合由壳体提供的螺纹的螺旋槽。 剂量旋钮设置在剂量拨盘套筒的近端附近，并且活塞杆设置在壳体内。 活塞杆在剂量设定步骤期间是不可旋转的。 驱动器包括靠近驾驶员远端部分的内螺纹，并适于接合活塞杆的外螺纹。 管状离合器定位在剂量旋钮的远端附近并且可操作地耦合到剂量旋钮。 剂量拨片套筒可围绕管状离合器的至少一部分周向延伸。
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7.发明授权Drive assembly suitable for use in a drug delivery device and drug delivery device 有权适用于药物输送装置和药物输送装置的驱动装置公开(公告)号：US08882721B2
公开(公告)日：2014-11-11
申请号：US12991471
申请日：2009-05-09
CPC分类号： A61M5/31593 , A61M5/31541 , A61M5/31551 , A61M5/31555 , A61M2005/3125 , A61M2005/3126 , A61M2005/3152
摘要： A drive assembly for use in a drug delivery device is proposed, the drive assembly comprising: a housing having a proximal end and a distal end; an axis extending between the proximal end and the distal end; at least one drive member; a piston rod adapted to be driven along the axis by the drive member; an indicator adapted to provide positional information about a position of the piston rod relative to the proximal end, wherein the indicator and the piston rod are configured to convert a movement of the piston rod with respect to the housing into a rotational movement of the indicator. Additionally, a drug delivery device comprising the drive assembly is provided for.
摘要翻译： 提出了一种用于药物输送装置的驱动组件，该驱动组件包括：具有近端和远端的壳体; 在近端和远端之间延伸的轴; 至少一个驱动构件; 活塞杆，其适于通过所述驱动构件沿着所述轴线驱动; 指示器，其适于提供关于活塞杆相对于近端的位置的位置信息，其中所述指示器和所述活塞杆构造成将所述活塞杆相对于所述壳体的运动转换为所述指示器的旋转运动。 另外，提供包括驱动组件的药物递送装置。
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公开(公告)号：US20140025016A1
公开(公告)日：2014-01-23
申请号：US14007086
申请日：2012-03-20
IPC分类号： A61M5/315
CPC分类号： A61M5/31533 , A61M5/24 , A61M5/31525 , A61M5/31535 , A61M5/31565 , A61M5/31566
摘要： A dose setting mechanism for a resettable drug delivery device is provided comprising a dose setting member and a drive member for driving a piston rod in a distal direction during dose dispensing, wherein the drive member comprises a proximal drive member and a distal drive member. Further, a first clutch is provided for releasably coupling the proximal drive member and the distal drive member. A spring means biases the proximal drive member and the distal drive member in the coupled state during dose setting and dose dispensing. According to one aspect of the invention engaging means are provided associated to the proximal drive member and to the dose setting member, wherein the engaging means are designed and arranged such that the proximal drive member entrains the dose setting member in the distal direction during dose setting but allows a relative axial movement of the proximal drive member with respect to the dose setting member in the proximal direction. Further, the invention refers to an injection device with such a dose setting mechanism.
摘要翻译： 提供了一种用于可重置药物输送装置的剂量设定机构，包括剂量设定部件和用于在剂量分配期间沿远端方向驱动活塞杆的驱动部件，其中驱动部件包括近侧驱动部件和远侧驱动部件。 此外，设置第一离合器用于可释放地联接近侧驱动构件和远侧驱动构件。 弹簧装置在剂量设定和剂量分配期间以耦合状态偏压近侧驱动构件和远侧驱动构件。 根据本发明的一个方面，提供了与近侧驱动构件和剂量设定构件相关联的接合装置，其中接合装置被设计和布置成使得近侧驱动构件在剂量设定期间沿远端方向夹带剂量设定构件 但允许近侧驱动构件相对于剂量设定构件在近端方向上的相对轴向移动。 此外，本发明涉及具有这种剂量设定机构的注射装置。
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公开(公告)号：US20140012208A1
公开(公告)日：2014-01-09
申请号：US14005879
申请日：2012-03-22
IPC分类号： A61M5/315
CPC分类号： A61M5/31528 , A61M5/24 , A61M5/3146 , A61M5/31543 , A61M5/31573 , A61M2005/2488 , A61M2005/3142 , A61M2005/3152 , A61M2205/581 , A61M2205/582
摘要： A resettable drug delivery device is provided comprising a body, a cartridge holder for receiving a cartridge, and means for releasably coupling the cartridge holder to the body or the dose setting mechanism. During an initial rotational coupling movement of the cartridge holder relative to the body or the dose setting mechanism the cartridge holder is caused to move in a first axial direction relative to the body or the dose setting mechanism and during a continued rotational coupling movement of the cartridge holder relative to the body or the dose setting mechanism the cartridge holder is caused to move in a second, contrary axial direction.
摘要翻译： 提供了一种可重置的药物输送装置，其包括主体，用于接收药筒的药筒保持器和用于将药筒保持器可释放地联接到身体或剂量设定机构的装置。 在盒保持器相对于身体或剂量设定机构的初始旋转联接运动期间，使盒保持器相对于身体或剂量设定机构在第一轴向方向上移动，并且在盒的持续旋转联接运动期间 保持器相对于身体或剂量设定机构使药筒保持器在第二相反轴向方向上移动。
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公开(公告)号：US07935088B2
公开(公告)日：2011-05-03
申请号：US11520598
申请日：2006-09-14
IPC分类号： A61M5/00
CPC分类号： A61M5/24 , A61M5/31528 , A61M5/31533 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31546 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31565 , A61M5/31568 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M5/32 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要： A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.
摘要翻译： 公开了一种适用于药物输送装置的驱动机构。 驱动机构可以与注射器型药物递送装置一起使用，例如允许用户设定递送剂量的那些。 驱动机构可以包括壳体，剂量拨号套筒和驱动套筒。 离合器构造成当剂量拨盘套筒和驱动套筒通过离合器联接时允许驱动套筒和剂量拨盘套筒相对于壳体旋转。 相反，当剂量拨号套筒和驱动套筒处于脱耦合状态时，允许剂量拨盘套筒相对于壳体的旋转，并且防止驱动套筒相对于壳体的旋转。 在脱耦合状态下，驱动套筒的轴向运动在纵向方向上传递力，用于致动药物输送装置。
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