公开(公告)号：US08180454B2

公开(公告)日：2012-05-15

申请号：US11607201

申请日：2006-12-01

申请人： Robert J. Greenberg ,  Ione Fine ,  Arup Roy ,  Matthew J. McMahon ,  Mark S. Humayun ,  James David Weiland ,  Alan M. Horsager ,  Dao Min Zhou ,  Amy Hines ,  Sumit Yadav ,  Rongqing Dai

发明人： Robert J. Greenberg ,  Ione Fine ,  Arup Roy ,  Matthew J. McMahon ,  Mark S. Humayun ,  James David Weiland ,  Alan M. Horsager ,  Dao Min Zhou ,  Amy Hines ,  Sumit Yadav ,  Rongqing Dai

IPC分类号： A61N1/18

CPC分类号： A61N1/0543 ,  A61N1/36046 ,  A61N1/37247

摘要： The invention is a method of automatically adjusting an electrode array to the neural characteristics of an individual subject. The response to electrical neural stimulation varies from subject to subject. Measure of impedance may be used to predict the electrode height from the neural tissue and, thereby, predict the threshold of perception. Alternatively, electrode height may be measured directly to predict the threshold of perception. Also, impedance measurement may be used to quickly identify defective electrodes and proper electrode placement.

摘要翻译： 本发明是一种将电极阵列自动调整为个体对象的神经特征的方法。 对电神经刺激的反应因受试者而异。 可以使用阻抗测量来预测来自神经组织的电极高度，从而预测感知的阈值。 或者，可以直接测量电极高度以预测感知阈值。 此外，阻抗测量可用于快速识别有缺陷的电极和适当的电极放置。

公开(公告)号：US20080114231A1

公开(公告)日：2008-05-15

申请号：US11924504

申请日：2007-10-25

申请人： Rongqing Dai ,  Robert J. Greenberg

发明人： Rongqing Dai ,  Robert J. Greenberg

IPC分类号： A61B5/042 ,  A61N1/05

CPC分类号： A61N1/378 ,  A61N1/36046

摘要： A power scheme for an implant on a human or animal body comprises: a charging circuit to provide power to deliver controlled stimulation currents to a body tissue; a capacitive storage arrangement connected with the charging circuit and charged by the charging circuit; a shunting arrangement to limit voltage on the capacitive storage arrangement; a driver array configured to transfer charges from the capacitive storage arrangement to the tissue; and an electrode array connected with the driver array and the tissue.

摘要翻译： 用于人体或动物体上的植入物的电力方案包括：充电电路，用于提供电力以将控制的刺激电流输送到身体组织; 与所述充电电路连接并由所述充电电路充电的电容性存储装置; 用于限制电容性存储装置上的电压的分流装置; 驱动器阵列，被配置为将电荷从电容性存储装置传送到组织; 以及与驱动器阵列和组织连接的电极阵列。

公开(公告)号：US08660660B2

公开(公告)日：2014-02-25

申请号：US11598965

申请日：2006-11-14

申请人： Rongqing Dai ,  Robert J. Greenberg

发明人： Rongqing Dai ,  Robert J. Greenberg

IPC分类号： A61N1/08

CPC分类号： A61N1/378 ,  A61N1/36046

摘要： A power scheme for an implant on a human or animal body comprises: a charging circuit to provide power to deliver controlled stimulation currents to a body tissue; a capacitive storage arrangement connected with the charging circuit and charged by the charging circuit; a shunting arrangement to limit voltage on the capacitive storage arrangement; a driver array configured to transfer charges from the capacitive storage arrangement to the tissue; and an electrode array connected with the driver array and the tissue.

摘要翻译： 用于人体或动物体上的植入物的电力方案包括：充电电路，用于提供电力以将控制的刺激电流输送到身体组织; 与所述充电电路连接并由所述充电电路充电的电容性存储装置; 用于限制电容性存储装置上的电压的分流装置; 驱动器阵列，被配置为将电荷从电容性存储装置传送到组织; 以及与驱动器阵列和组织连接的电极阵列。

公开(公告)号：US08521287B2

公开(公告)日：2013-08-27

申请号：US11924504

申请日：2007-10-25

申请人： Rongqing Dai ,  Robert J. Greenberg

发明人： Rongqing Dai ,  Robert J. Greenberg

IPC分类号： A61N1/18

CPC分类号： A61N1/378 ,  A61N1/36046

摘要： A power scheme for an implant on a human or animal body comprises: a charging circuit to provide power to deliver controlled stimulation currents to a body tissue; a capacitive storage arrangement connected with the charging circuit and charged by the charging circuit; a shunting arrangement to limit voltage on the capacitive storage arrangement; a driver array configured to transfer charges from the capacitive storage arrangement to the tissue; and an electrode array connected with the driver array and the tissue.

摘要翻译： 用于人体或动物体上的植入物的电力方案包括：充电电路，用于提供电力以将控制的刺激电流输送到身体组织; 与所述充电电路连接并由所述充电电路充电的电容性存储装置; 用于限制电容性存储装置上的电压的分流装置; 驱动器阵列，被配置为将电荷从电容性存储装置传送到组织; 以及与驱动器阵列和组织连接的电极阵列。

公开(公告)号：US20080294223A1

公开(公告)日：2008-11-27

申请号：US11925285

申请日：2007-10-26

申请人： Robert J. Greenberg ,  Ione Fine ,  Arup Roy ,  Matthew J. McMahon ,  Mark S. Humayun ,  James David Weiland ,  Alan M. Horsager ,  Dao Min Zhou ,  Amy Hines ,  Sumit Yadav ,  Rongqing Dai

发明人： Robert J. Greenberg ,  Ione Fine ,  Arup Roy ,  Matthew J. McMahon ,  Mark S. Humayun ,  James David Weiland ,  Alan M. Horsager ,  Dao Min Zhou ,  Amy Hines ,  Sumit Yadav ,  Rongqing Dai

IPC分类号： A61N1/36

CPC分类号： A61N1/0543 ,  A61N1/36046 ,  A61N1/37247

摘要： The invention is a method of automatically adjusting an electrode array to the neural characteristics of an individual subject. The response to electrical neural stimulation varies from subject to subject. Measure of impedance may be used to predict the electrode height from the neural tissue and, thereby, predict the threshold of perception. Alternatively, electrode height may be measured directly to predict the threshold of perception. Also, impedance measurement may be used to quickly identify defective electrodes and proper electrode placement.

摘要翻译： 本发明是一种将电极阵列自动调整为个体对象的神经特征的方法。 对电神经刺激的反应因受试者而异。 可以使用阻抗测量来预测来自神经组织的电极高度，从而预测感知的阈值。 或者，可以直接测量电极高度以预测感知阈值。 此外，阻抗测量可用于快速识别有缺陷的电极和适当的电极放置。

公开(公告)号：US20080082147A1

公开(公告)日：2008-04-03

申请号：US11924423

申请日：2007-10-25

申请人： Rongqing Dai ,  Dao Min Zhou ,  Robert J. Greenberg ,  John Gord

发明人： Rongqing Dai ,  Dao Min Zhou ,  Robert J. Greenberg ,  John Gord

IPC分类号： A61N1/02

CPC分类号： A61N1/37229 ,  A61N1/36046 ,  A61N1/3787

摘要： Methods and devices for inductively coupled implants on the human or animal body are disclosed. An external coil assembly to be used with the implant has a transmitting coil and one or more receiving coils. The number of the receiving coils, their distance from the transmitting coil and their shape is chosen to reduce the influence of a noise signal received by the external coil assembly.

摘要翻译： 公开了用于人体或动物体上的电感耦合植入物的方法和装置。 与植入物一起使用的外部线圈组件具有发射线圈和一个或多个接收线圈。 选择接收线圈的数量，它们与发射线圈的距离及其形状，以减少由外部线圈组件接收的噪声信号的影响。

公开(公告)号：US08190267B2

公开(公告)日：2012-05-29

申请号：US11925285

申请日：2007-10-26

申请人： Robert J. Greenberg ,  Ione Fine ,  Arup Roy ,  Matthew J. McMahon ,  Mark S. Humayun ,  James David Weiland ,  Alan M. Horsager ,  Dao Min Zhou ,  Amy Hines ,  Sumit Yadav ,  Rongqing Dai

发明人： Robert J. Greenberg ,  Ione Fine ,  Arup Roy ,  Matthew J. McMahon ,  Mark S. Humayun ,  James David Weiland ,  Alan M. Horsager ,  Dao Min Zhou ,  Amy Hines ,  Sumit Yadav ,  Rongqing Dai

IPC分类号： A61N1/05

CPC分类号： A61N1/0543 ,  A61N1/36046 ,  A61N1/37247

摘要： The invention is a method of automatically adjusting an electrode array to the neural characteristics of an individual subject. The response to electrical neural stimulation varies from subject to subject. Measure of impedance may be used to predict the electrode height from the neural tissue and, thereby, predict the threshold of perception. Alternatively, electrode height may be measured directly to predict the threshold of perception. Also, impedance measurement may be used to quickly identify defective electrodes and proper electrode placement.

公开(公告)号：US20090228069A1

公开(公告)日：2009-09-10

申请号：US12416824

申请日：2009-04-01

申请人： Rongqing Dai ,  Robert J. Greenberg

发明人： Rongqing Dai ,  Robert J. Greenberg

IPC分类号： A61F9/08 ,  A61N1/08 ,  A61N1/36

CPC分类号： A61N1/378 ,  A61N1/36046

摘要： A power scheme for an implant on a human or animal body comprises: a charging circuit to provide power to deliver controlled stimulation currents to a body tissue; a capacitive storage arrangement connected with the charging circuit and charged by the charging circuit; a shunting arrangement to limit voltage on the capacitive storage arrangement; a driver array configured to transfer charges from the capacitive storage arrangement to the tissue; and an electrode array connected with the driver array and the tissue.

摘要翻译： 用于人体或动物体上的植入物的电力方案包括：充电电路，用于提供电力以将控制的刺激电流输送到身体组织; 与所述充电电路连接并由所述充电电路充电的电容性存储装置; 用于限制电容性存储装置上的电压的分流装置; 驱动器阵列，被配置为将电荷从电容性存储装置传送到组织; 以及与驱动器阵列和组织连接的电极阵列。

公开(公告)号：US20080275362A1

公开(公告)日：2008-11-06

申请号：US11924436

申请日：2007-10-25

申请人： Amy Chu Peishuan Hines ,  Dao Min Zhou ,  Arup Roy ,  Rongqing Dai ,  Robert J. Greenberg

发明人： Amy Chu Peishuan Hines ,  Dao Min Zhou ,  Arup Roy ,  Rongqing Dai ,  Robert J. Greenberg

IPC分类号： A61B5/053

CPC分类号： A61N1/36046 ,  A61N1/0543

摘要： The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.

摘要翻译： 本发明是一种用于测量稳定且可再现的电极组织阻抗的方法，包括预处理电极 - 组织界面。 本发明的另一方面是一种用于视觉假体的刺激系统，其产生用于预处理电极 - 组织界面的刺激信号，所述刺激信号包括计算机; 软件，装在计算机中，适用于执行具有多个电极的视觉假体的刺激方法; 视频处理单元; 和植入的神经元刺激器。

公开(公告)号：US20080082140A1

公开(公告)日：2008-04-03

申请号：US11906167

申请日：2007-09-28

申请人： Amy Chu Peishuan Hines ,  Dao Min Zhou ,  Arup Roy ,  Rongqing Dai ,  Robert J. Greenberg

发明人： Amy Chu Peishuan Hines ,  Dao Min Zhou ,  Arup Roy ,  Rongqing Dai ,  Robert J. Greenberg

IPC分类号： A61N1/00

CPC分类号： A61N1/36046 ,  A61N1/0543

摘要： The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.

摘要翻译： 本发明是一种用于测量稳定且可再现的电极组织阻抗的方法，包括预处理电极 - 组织界面。 本发明的另一方面是一种用于视觉假体的刺激系统，其产生用于预处理电极 - 组织界面的刺激信号，所述刺激信号包括计算机; 软件，装在计算机中，适用于执行具有多个电极的视觉假体的刺激方法; 视频处理单元; 和植入的神经元刺激器。