公开(公告)号：US09022993B2

公开(公告)日：2015-05-05

申请号：US13509602

申请日：2010-12-06

申请人： Uwe Dasbach ,  Steffen Raab ,  Marianne Rottluff

发明人： Uwe Dasbach ,  Steffen Raab ,  Marianne Rottluff

IPC分类号： A61M5/00 ,  A61M5/315 ,  A61M5/24 ,  A61M5/48 ,  A61M5/31

CPC分类号： A61M5/3156 ,  A61M5/24 ,  A61M5/31555 ,  A61M5/31585 ,  A61M5/31593 ,  A61M5/482 ,  A61M2005/3103 ,  A61M2005/3126

摘要： A drive assembly for a drug delivery device is presented having a housing with a proximal end and a distal end, a drive member, and a piston rod. A longitudinal axis extends between the proximal end and the distal end and the piston rod is axially moveable relative to the housing. The piston rod has a guide track and the drive member has a guide piece disposed and movable in the guide track. The guide track is configured with at least one section which is oblique relative to the longitudinal axis and defines a displacement for dispensing a single pre-set dose of medication during a relative movement between the guide piece and the piston rod when the guide piece cooperates with the oblique section between a distal final area of the oblique section and a proximal final area of the oblique section.

摘要翻译： 本发明提供了一种用于药物输送装置的驱动组件，其具有具有近端和远端的壳体，驱动构件和活塞杆。 纵向轴线在近端和远端之间延伸，并且活塞杆相对于壳体可轴向移动。 活塞杆具有导轨，并且驱动构件具有设置并可在引导轨道中移动的引导件。 所述导轨配置有至少一个相对于所述纵向轴线倾斜的部分，并且当所述导向件与所述导向件与所述活塞杆配合时在所述导向件和所述活塞杆之间的相对运动期间限定用于分配单个预设剂量的药物的位移 倾斜部分的远端最终区域与倾斜部分的近端部区域之间的倾斜部分。

公开(公告)号：US20130338585A1

公开(公告)日：2013-12-19

申请号：US14002177

申请日：2012-03-15

申请人： Stefan Wendland ,  Steffen Raab ,  Peggy Rabe

发明人： Stefan Wendland ,  Steffen Raab ,  Peggy Rabe

IPC分类号： A61M5/50

CPC分类号： A61M5/5086 ,  A61M5/24 ,  A61M5/50

摘要： The present invention relates to a drug delivery device for administering a dose of a medicament by way of injection, the device comprising of a housing to receive a cartridge at least partially filled with a medicament and being sealed with a piston slidably disposed therein, a drive mechanism having a piston rod to be displaced in a distal direction to operably engage with the piston of the cartridge, an actuation means operably engaged with the drive mechanism to prepare and/or to initiate a dose dispensing action of the drive mechanism, and a protective member adapted to impede actuation of the actuation means, wherein the protective member is releasably connected to the housing by means of a breakable seal.

摘要翻译： 本发明涉及一种用于通过注射给药一剂药物的药物递送装置，该装置包括：壳体，用于容纳至少部分地填充有药物并且可滑动地设置在其中的活塞密封的药筒;驱动器 机构，其具有活动杆，所述活塞杆在远侧方向上移动以与所述药筒的活塞可操作地接合;致动装置，与所述驱动机构可操作地接合以准备和/或启动所述驱动机构的剂量分配动作;以及保护 适于阻止致动装置的致动的构件，其中保护构件通过可破坏的密封件可释放地连接到壳体。

公开(公告)号：US20130211342A1

公开(公告)日：2013-08-15

申请号：US13701969

申请日：2011-06-09

申请人： Steffen Raab ,  Mark Philip Horlock ,  Stephen David Butler

发明人： Steffen Raab ,  Mark Philip Horlock ,  Stephen David Butler

IPC分类号： A61M5/315

CPC分类号： A61M5/31511 ,  A61M5/24 ,  A61M5/31543 ,  A61M5/3155 ,  A61M5/31551 ,  A61M5/31553 ,  A61M5/31555 ,  A61M5/3158 ,  A61M5/31583 ,  A61M5/31585

摘要： An assembly for a drug delivery device is provided, comprising a housing, a rotation member adapted and arranged to be rotated in a first and in a second rotational direction with respect to the housing in an operational mode of the assembly, a drive member which is configured to mechanically cooperate with the rotation member such that the drive member follows rotation of the rotation member when the rotation member is rotated in the second rotational direction and such that the rotation member rotates with respect to the drive member when the rotation member is rotated in the first rotational direction, and a piston rod. The assembly further comprises at least one biasing member which is adapted and arranged to provide a force tending to bring the rotation member and the drive member out of mechanical cooperation in the operational mode. The assembly is switchable from the operational mode into a reset mode. For switching from the operational mode into the reset mode, the biasing member is configured to drive a relative axial movement between the drive member and the rotation member such that the rotation member and the drive member are brought out of mechanical cooperation. Furthermore, a drug delivery device is provided.

摘要翻译： 提供了一种用于药物输送装置的组件，包括壳体，旋转构件，其适于并布置成在组件的操作模式下相对于壳体在第一和第二旋转方向上旋转;驱动构件， 被构造成与所述旋转构件机械配合，使得当所述旋转构件沿所述第二旋转方向旋转时，所述驱动构件沿着所述旋转构件的旋转，并且使得当所述旋转构件旋转时所述旋转构件相对于所述驱动构件旋转 第一旋转方向和活塞杆。 该组件还包括至少一个偏置构件，该至少一个偏置构件适于并布置成提供趋向于使操作模式中的旋转构件和驱动构件脱离机械协作的力。 组件可以从操作模式切换到复位模式。 为了从操作模式切换到复位模式，偏置构件被构造成驱动驱动构件和旋转构件之间的相对轴向运动，使得旋转构件和驱动构件脱离机械协作。 此外，提供了药物输送装置。

公开(公告)号：US20130204203A1

公开(公告)日：2013-08-08

申请号：US13576671

申请日：2011-03-16

申请人： Lutz Mueller ,  Claudia Matthias ,  Michael Helmer ,  Steffen Raab ,  Axel Forstreutter

发明人： Lutz Mueller ,  Claudia Matthias ,  Michael Helmer ,  Steffen Raab ,  Axel Forstreutter

IPC分类号： A61M5/315

CPC分类号： A61M5/31548 ,  A61M5/24 ,  A61M5/3146 ,  A61M5/31595 ,  A61M2005/2488 ,  A61M2005/2492 ,  A61M2207/00 ,  Y10T29/49826

摘要： The present invention relates to a drug delivery device for dispensing of a dose of a medicinal product, comprising: a first housing component (12, 52; 62) adapted to receive a cartridge (16) comprising the medicinal product and further comprising a piston (18) slidably arranged therein in an axial direction, a second housing component (14; 54; 64) adapted to receive a dose dispensing mechanism having a piston rod (20) to be operably engaged with the cartridge's piston (18), wherein the first and the second housing components (12, 14; 52, 54; 62, 64) are displaceably arranged in axial direction relative to each other for reducing an axial distance (34) between the piston (18) and the piston rod (20) to a pre-defined degree, and an interlock means (30) adapted to interact with at least one of first and second housing components (12, 14; 52, 54; 62, 64) for mutually locking into position first and second housing components (12, 14; 52, 54; 62, 64).

摘要翻译： 本发明涉及用于分配药物产品剂量的药物递送装置，包括：第一壳体部件（12,52; 62），适于接收包括药物产品的药筒（16），并且还包括活塞（ 18），其沿轴向方向可滑动地布置在其中;第二壳体部件（14; 54; 64），其适于接收剂量分配机构，所述剂量分配机构具有可与所述药筒活塞（18）可操作地接合的活塞杆（20），其中所述第一 并且所述第二壳体部件（12,14; 52,54; 62,64）可相对于彼此沿轴向方向可移位地设置，以便减少所述活塞（18）和所述活塞杆（20）之间的轴向距离（34） 以及互锁装置（30），其适于与第一和第二壳体部件（12,14; 52,54; 62,64）中的至少一个相互作用，以相互锁定到位置第一和第二壳体部件（ 12,14; 52,54; 62,64）。

公开(公告)号：US20130046248A1

公开(公告)日：2013-02-21

申请号：US13575352

申请日：2011-02-02

申请人： Steffen Raab

发明人： Steffen Raab

IPC分类号： A61M5/315

CPC分类号： A61M5/31585 ,  A61M5/31541 ,  A61M5/31555 ,  A61M5/31593

摘要： An assembly for a drug delivery device comprises a housing, at least one stop feature and at least one blocking member. For setting a dose of a drug, the stop feature is configured to be rotated in a dose setting direction with respect to the blocking member and with respect to the housing. For delivering the set dose of the drug, the blocking member is configured to be axially displaced with respect to the stop feature away from an axial starting position and towards an axial interaction position. When the blocking member is in the axial starting position, the blocking member is axially offset from the stop feature and, when the blocking member is in the axial interaction position, the blocking member is configured to mechanically cooperate with the stop feature such that rotation of the stop feature in the dose setting direction with respect to the housing is prevented.

摘要翻译： 用于药物递送装置的组件包括壳体，至少一个止动部件和至少一个阻塞部件。 为了设置药物的剂量，停止特征被配置为相对于阻塞构件和相对于壳体在剂量设定方向上旋转。 为了传递药物的设定剂量，阻挡构件被构造成相对于止动件远离轴向起始位置并且朝向轴向相互作用位置轴向移位。 当阻挡构件处于轴向起始位置时，阻挡构件从止动构件轴向偏移，并且当阻挡构件处于轴向相互作用位置时，阻挡构件构造成与止动构件机械配合， 阻止了相对于壳体的剂量设定方向的停止特征。

公开(公告)号：US20130046245A1

公开(公告)日：2013-02-21

申请号：US13575353

申请日：2011-01-31

申请人： Steffen Raab ,  Sandra Arnhold

发明人： Steffen Raab ,  Sandra Arnhold

IPC分类号： A61M5/24

CPC分类号： A61M5/24 ,  A61M5/3134 ,  A61M5/347 ,  A61M2005/2437 ,  A61M2005/2488

摘要： A cartridge holder, which has a distal end and a proximal end, comprises a coupling housing portion in which a cartridge can be inserted at least partly. The coupling housing portion is configured to be coupled to a part of a drug delivery device. The cartridge holder further comprises a fixing member which is connected with the coupling housing portion. The fixing member is moveable radially inwardly to a position in which the fixing member is suitable for securing the cartridge against distal displacement of the cartridge.

摘要翻译： 具有远端和近端的药筒保持器包括联接器壳体部分，其中药筒可以至少部分插入其中。 联接器壳体部分被配置为联接到药物递送装置的一部分。 盒架还包括与联接器壳体部分连接的固定构件。 固定构件可径向向内移动到固定构件适合于固定盒抵抗盒的远端位移的位置。

公开(公告)号：US20120101452A1

公开(公告)日：2012-04-26

申请号：US13258160

申请日：2010-03-31

申请人： Michael Harms ,  Volker Korger ,  Uwe Dasbach ,  Steffen Raab

发明人： Michael Harms ,  Volker Korger ,  Uwe Dasbach ,  Steffen Raab

IPC分类号： A61M5/315

CPC分类号： A61M5/31543 ,  A61M5/24 ,  A61M5/31525 ,  A61M5/31528 ,  A61M2005/2481

摘要： A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated.

摘要翻译： 身体中的机构用于驱动活塞杆，并且包括用于在输送药物的同时引导活塞杆相对于身体的运动的装置。 提供了用于将活塞杆从用于引导运动的装置释放的另外的装置，从而使活塞杆能够复位到起始位置，特别是在容器被排空并被重新填充之后。 该装置的构造使得活塞杆的复位变得容易。

公开(公告)号：US20120083748A1

公开(公告)日：2012-04-05

申请号：US13258158

申请日：2010-03-31

申请人： Michael Harms ,  Volker Korger ,  Uwe Dasbach ,  Steffen Raab

发明人： Michael Harms ,  Volker Korger ,  Uwe Dasbach ,  Steffen Raab

IPC分类号： A61M5/315

CPC分类号： A61M5/31525 ,  A61M5/178 ,  A61M5/315 ,  A61M5/31543 ,  A61M2005/3115

摘要： A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated by a stop element inhibiting a reversal of the movement of the piston rod when being reset.

摘要翻译： 身体中的机构用于驱动活塞杆，并且包括用于在输送药物的同时引导活塞杆相对于身体的运动的装置。 提供了用于将活塞杆从用于引导运动的装置释放的另外的装置，从而使活塞杆能够复位到起始位置，特别是在容器被排空并被重新填充之后。 该装置的结构是这样一种方式：活塞杆的复位由止动件有助于在复位时阻止活塞杆运动反转。

公开(公告)号：US20120078195A1

公开(公告)日：2012-03-29

申请号：US13258155

申请日：2010-03-31

申请人： Michael Harms ,  Steffen Raab ,  Uwe Dasbach ,  Udo Stauder

发明人： Michael Harms ,  Steffen Raab ,  Uwe Dasbach ,  Udo Stauder

IPC分类号： A61M5/31

CPC分类号： A61M5/3129 ,  A61M5/3155 ,  A61M2005/3125 ,  A61M2205/6063

摘要： The body of a portable drug delivery device, especially an injection pen, is provided on its outer surface with a recess, in which directly accessible information is displayed. The information is protected against damages during everyday use by the recessed location.

摘要翻译： 便携式药物输送装置，特别是注射笔的身体在其外表面上设置有凹部，其中显示直接可访问的信息。 这些信息在日常使用过程中受到隐藏的位置的保护。

公开(公告)号：US20120010576A1

公开(公告)日：2012-01-12

申请号：US13143040

申请日：2010-01-19

申请人： Steffen Raab ,  Ulrich Brüggemann

发明人： Steffen Raab ,  Ulrich Brüggemann

IPC分类号： A61M5/315

CPC分类号： A61M5/31585 ,  A61M5/20 ,  A61M5/24 ,  A61M5/30 ,  A61M5/31568 ,  A61M5/3157 ,  A61M5/31593

摘要： A drive assembly suitable for a medication delivery device comprises a housing, a drive member, a piston rod, a rotation sleeve, a guide member and a biasing member. The rotation sleeve is arranged to be displaced in a distal direction when the drive member is displaced in the distal direction by mechanical interaction of the drive member and the rotation sleeve with the rotation sleeve and the drive member both being guided axially by the at guide member. The biasing member exerts a force on the rotation sleeve acting in the proximal direction, said force being transformed into a rotational movement of the rotation sleeve. The rotational movement of the rotation sleeve being transformed into a rotational movement of the piston rod.

摘要翻译： 适用于药物输送装置的驱动组件包括壳体，驱动构件，活塞杆，旋转套筒，引导构件和偏置构件。 旋转套筒被布置成当驱动构件通过驱动构件和旋转套筒与旋转套筒的机械相互作用而在远侧方向上移位时，其沿远侧方向移位，并且驱动构件均由导向构件 。 偏置构件对旋转套筒施加作用在近端方向上的力，所述力被转换成旋转套筒的旋转运动。 旋转套筒的旋转运动转变为活塞杆的旋转运动。