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公开(公告)号：US20070135809A1
公开(公告)日：2007-06-14
申请号：US11286257
申请日：2005-11-23
Applicant: David Utley , Robert Garabedian , Michael Wallace
Inventor： David Utley , Robert Garabedian , Michael Wallace
IPC: A61B18/14
CPC classification number: A61B18/1492 , A61B18/18 , A61B2018/00214 , A61B2018/0022 , A61B2018/00577 , A61B2018/1495 , A61B2018/1807
Abstract: Apparatus for treating abnormal mucosa in an alimentary tract are provided. The apparatus include an ablation structure configured to be removably coupled to an endoscope and a deflection mechanism adapted to move the ablation structure with respect to the endoscope and toward a tissue surface.
Abstract translation: 提供了用于治疗消化道异常粘膜的装置。 该装置包括被配置为可移除地联接到内窥镜的消融结构和适于使消融结构相对于内窥镜移动并朝向组织表面的偏转机构。
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公开(公告)号：US20060224157A1
公开(公告)日：2006-10-05
申请号：US11446771
申请日：2006-06-05
Applicant: David Utley , Scott West , John Gaiser , Rachel Croft
Inventor： David Utley , Scott West , John Gaiser , Rachel Croft
IPC: A61B18/14
CPC classification number: A61B18/1477 , A61B1/31 , A61B18/1485 , A61B2018/00267 , A61B2018/00482 , A61B2018/00553 , A61B2018/00797 , A61B2018/0091 , A61B2018/00916 , A61B2018/046 , A61B2090/3782 , A61B2218/007
Abstract: A sphincter tissue region is treated using a support structure sized for advancement into the anal canal. At least one electrode is carried by the structure. A mechanism is coupled to the electrode to move the electrode between a first position retracted in the support structure and a second position extended from the support structure through surface tissue to penetrate a subsurface tissue region at or near a sphincter in the anal canal. A cable is coupled to the electrode to conduct energy for application by the electrode to form a lesion in the subsurface tissue region.
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33.发明申请Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors 有权通过检测和消融胃食管神经和受体来治疗胃反流的方法公开(公告)号：US20060015162A1
公开(公告)日：2006-01-19
申请号：US11230801
申请日：2005-09-20
Applicant: Stuart Edward , John Gaiser , David Utley
Inventor： Stuart Edward , John Gaiser , David Utley
CPC classification number: A61B18/1233 , A61B18/1477 , A61B18/1492 , A61B90/39 , A61B2017/00039 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00142 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00553 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00738 , A61B2018/00791 , A61B2018/00821 , A61B2018/00839 , A61B2018/00875 , A61B2018/00898 , A61B2018/0091 , A61B2018/00982 , A61B2018/0237 , A61B2018/046 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1467 , A61B2090/064 , A61B2090/3782 , A61B2218/002 , A61N1/06
Abstract: A method of treating a sphincter provides a sphincter electropotential mapping device with at least one of a mapping electrode or a treatment electrode. The sphincter electropotential mapping device is introduced into at least a portion of the sphincter, the lower esophageal sphincter, stomach, the cardia or the fundus. Bioelectric activity causing a relaxation of the sphincter is detected and energy is delivered from either the mapping electrode or the treatment electrode to treat the bioelectric activity. A method of treating a sphincter provides a sphincter electropotential mapping device with at least one of a mapping electrode or a treatment electrode. The sphincter electropotential mapping device is introduced into at least a portion of the sphincter, the lower esophageal sphincter, stomach, the cardia or the fundus. Bioelectric activity causing a relaxation of the sphincter is detected and energy is delivered from either the mapping electrode or the treatment electrode to treat the bioelectric activity.
Abstract translation: 治疗括约肌的方法提供具有映射电极或治疗电极中的至少一个的括约肌电位映射装置。 括约肌电位映射装置被引入至少一部分括约肌，食管下括约肌，胃，贲门或眼底。 检测到引起松弛括约肌的生物电活性，并从映射电极或治疗电极传递能量以处理生物电活性。 治疗括约肌的方法提供具有映射电极或治疗电极中的至少一个的括约肌电位映射装置。 括约肌电位映射装置被引入至少一部分括约肌，食管下括约肌，胃，贲门或眼底。 检测到引起松弛括约肌的生物电活性，并从映射电极或治疗电极传递能量以处理生物电活性。
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公开(公告)号：US20050159743A1
公开(公告)日：2005-07-21
申请号：US11079697
申请日：2005-03-14
Applicant: Stuart Edwards , David Utley , Ronald Lax , John Gaiser
Inventor： Stuart Edwards , David Utley , Ronald Lax , John Gaiser
CPC classification number: A61B18/1492 , A61B18/1206 , A61B18/1477 , A61B18/18 , A61B2018/00011 , A61B2018/00029 , A61B2018/00047 , A61B2018/00214 , A61B2018/0022 , A61B2018/00494 , A61B2018/00553 , A61B2018/00666 , A61B2018/00678 , A61B2018/00684 , A61B2018/00702 , A61B2018/00708 , A61B2018/00726 , A61B2018/00744 , A61B2018/00791 , A61B2018/00875 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1425 , A61B2218/002
Abstract: A method for treating a sphincter provides a polymer material having a liquid state. The method also provides a catheter having a distal end, a tissue piercing device carried by the distal end, and an energy delivery device coupled to the tissue piercing device. The tissue piercing device has a lumen. The method introduces the catheter into an esophagus and pierces an exterior sphincter tissue surface within with the tissue piercing device. The method advances the tissue piercing device into an interior sphincter tissue site and conveys the polymer material while in a liquid state through the lumen into the interior sphincter tissue site. The method delivers energy to the tissue piercing device to transform the polymer material into a less liquid state within the interior sphincter tissue site, to thereby remodel the sphincter.
Abstract translation: 用于治疗括约肌的方法提供具有液体状态的聚合物材料。 该方法还提供了具有远端的导管，由远端承载的组织刺穿装置，以及耦合到组织刺穿装置的能量输送装置。 组织穿刺装置具有内腔。 该方法将导管引入食道并刺穿组织穿刺装置内的外括约肌组织表面。 该方法使组织穿刺装置进入内部括约肌组织部位，并将液体状态下的聚合物材料通过内腔输送到内括约肌组织部位。 该方法将能量传递到组织刺穿装置，以将聚合物材料转变成内部括约肌组织部位内的较少液体状态，从而改变括约肌。
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公开(公告)号：US20050107829A1
公开(公告)日：2005-05-19
申请号：US10963025
申请日：2004-10-12
Applicant: Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Qin
Inventor： Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Qin
CPC classification number: A61B18/1492 , A61B18/12 , A61B18/1206 , A61B18/1477 , A61B18/1485 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
Abstract: Methods treat a tissue region. In one arrangement, the methods deploy an electrode on a support structure in a tissue region at or near the cardia of the stomach. In one embodiment, the support structure has a proximal region and a distal region. The proximal region is enlarged in comparison to the distal region, and the electrode is carried by the enlarged proximal surface. The methods advance the electrode in a path to penetrate the tissue region and couple the electrode to a source of radio frequency energy to ohmically heat tissue and create a lesion in the tissue region.
Abstract translation: 方法治疗组织区域。 在一种布置中，所述方法将电极部署在胃贲门处或附近的组织区域中的支撑结构上。 在一个实施例中，支撑结构具有近端区域和远侧区域。 近端区域与远侧区域相比放大，并且电极由扩大的近侧表面承载。 所述方法使电极在路径中前进以穿透组织区域并将电极耦合到射频能量源以欧姆加热组织并在组织区域中产生损伤。
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Patent Agency Ranking
公开(公告)号：US06358245B1
公开(公告)日：2002-03-19
申请号：US09305123
申请日：1999-05-04
Applicant: Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Chin
Inventor： Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Chin
IPC: A81B1804
CPC classification number: A61B18/1233 , A61B18/12 , A61B18/1206 , A61B18/14 , A61B18/1477 , A61B18/1485 , A61B18/1492 , A61B2018/00011 , A61B2018/00029 , A61B2018/00035 , A61B2018/00077 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00488 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007 , Y10S128/922
Abstract: Systems and methods deploy an electrode structure in contact with the tissue region. The electrode structure carries a sensor at a known location on the electrode structure to monitor an operating condition. The systems and methods provide an interface, which generate an idealized image of the electrode structure and an indicator image to represent the monitored operating condition in a spatial position on the idealized image corresponding to the location of the sensor on the electrode structure. The interface displays a view image comprising the idealized image and indicator image. The systems and methods cause the electrode structure to apply energy to heat the tissue region while the view image is displayed on the display screen.
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37.发明授权Expandable electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions 有权用于形成损伤以治疗括约肌和邻近组织区域功能障碍的可扩展电极组件公开(公告)号：US06258087B1
公开(公告)日：2001-07-10
申请号：US09304773
申请日：1999-05-04
Applicant: Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Chin
Inventor： Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Chin
IPC: A61B1818
CPC classification number: A61B18/1206 , A61B18/12 , A61B18/1477 , A61B18/1485 , A61B18/1492 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
Abstract: Expandable assemblies for treating a tissue region at or near a sphincter comprises a support basket formed from an array of spines. A mechanism flexes the spines to expand and collapse the basket. Electrodes carried by the spines for advancement in a path to penetrate the tissue region upon expansion of the basket. The basket can be formed from a mechanical array of molded, jointed spines, or from an extruded tube having axial slits forming the spines.
Abstract translation: 用于治疗括约肌处或附近的组织区域的可扩展组件包括由脊柱阵列形成的支撑篮。 一种机构使脊柱弯曲以使筐膨胀和折叠。 由脊柱承载的电极，用于在通过篮子膨胀时穿过组织区域的路径前进。 篮子可以由模制的，接合的刺的机械阵列形成，或者由具有形成脊柱的轴向狭缝的挤压管形成。
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公开(公告)号：US20110257646A1
公开(公告)日：2011-10-20
申请号：US12799169
申请日：2010-04-20
Applicant: David Utley , Scott West , John Gaiser , Rachel Croft
Inventor： David Utley , Scott West , John Gaiser , Rachel Croft
IPC: A61B18/18
CPC classification number: A61B18/1485 , A61B1/00087 , A61B8/12 , A61B18/02 , A61B18/1477 , A61B18/149 , A61B18/18 , A61B2017/00106 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00267 , A61B2018/005 , A61B2018/00553 , A61B2018/00642 , A61B2018/00702 , A61B2018/00791 , A61B2018/00982 , A61B2018/00994 , A61B2018/046 , A61B2018/1869 , A61B2018/2005
Abstract: A sphincter tissue region is treated using a support structure sized for advancement into the anal canal. At least one electrode is carried by the structure. A mechanism is coupled to the electrode to move the electrode between a first position retracted in the support structure and a second position extended from the support structure through surface tissue to penetrate a subsurface tissue region at or near a sphincter in the anal canal. A cable is coupled to the electrode to conduct energy for application by the electrode to form a lesion in the subsurface tissue region.
Abstract translation: 括约肌组织区域使用尺寸适合进入肛管的支撑结构来治疗。 该结构承载至少一个电极。 机构耦合到电极以在缩回到支撑结构中的第一位置和从支撑结构延伸穿过表面组织的第二位置之间移动电极，以穿透肛管内的括约肌处或附近的下表面组织区域。 电缆耦合到电极以传导电极施加的能量，以在地下组织区域中形成病变。
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39.发明申请公开(公告)号：US20070093879A1
公开(公告)日：2007-04-26
申请号：US11638958
申请日：2006-12-14
Applicant: Robin Bek , Jay Qin , John Gaiser , David Utley , Jame Bernitt
Inventor： Robin Bek , Jay Qin , John Gaiser , David Utley , Jame Bernitt
CPC classification number: A61B18/1477 , A61B18/00 , A61B18/1492 , A61B90/90 , A61B2017/00017 , A61B2017/00084 , A61B2017/00199 , A61B2017/00269 , A61B2017/00482 , A61B2018/0022 , A61B2018/00267 , A61B2018/00494 , A61B2018/00791 , A61B2018/00988 , A61B2090/0814
Abstract: A device carries a use monitoring element that possesses a state or condition that changes in response to use of the device and that is sensed when the device is presented for use. Reuse of the device is not permitted, if the use monitoring element indicates a prior use.
Abstract translation: 设备携带使用监视元件，其具有响应于设备的使用而改变的状态或状况，并且当该设备被呈现供使用时被感测。 如果使用监控元件表示事先使用，则不允许重新使用设备。
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公开(公告)号：US20060259029A1
公开(公告)日：2006-11-16
申请号：US11420714
申请日：2006-05-26
Applicant: David Utley , John Gaiser , Stuart Edwards , Scott West , Jay Qin
Inventor： David Utley , John Gaiser , Stuart Edwards , Scott West , Jay Qin
IPC: A61B18/18
CPC classification number: A61B18/1492 , A61B18/12 , A61B18/1206 , A61B18/1477 , A61B18/1485 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/3782 , A61B2218/002 , A61B2218/007
Abstract: Methods of accessing and ablating abnormal epithelium tissue in an alimentary canal are provided. The methods can include steps of (i) inserting an operative element into an alimentary canal such that the proximate to a portion of the alimentary canal having tissue to be ablated; and (ii) using the operative element to apply cryogenic ablation to a site of abnormal tissue.
Abstract translation: 提供了在消化道中获取和消融异常上皮组织的方法。 所述方法可以包括以下步骤：（i）将操作元件插入消化道，使得靠近消化道的一部分具有要消融的组织; 和（ii）使用手术元件将低温消融应用于异常组织的部位。
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