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公开(公告)号：US20100163777A1
公开(公告)日：2010-07-01
申请号：US12377661
申请日：2007-08-08
申请人： Kazumichi Nakahama
发明人： Kazumichi Nakahama
CPC分类号： A61K9/0009 , A61K9/5094 , A61K41/0052 , A61K49/1824 , A61K49/1857 , A61K49/1869 , B82Y5/00 , Y10T428/2982
摘要： Magnetic particles containing a magnetic material and a biodegradable polymeric compound; the magnetic particles having average particle diameter in the range of from 10 nm or more to 1,000 nm or less.
摘要翻译： 含有磁性材料和可生物降解的聚合物的磁性颗粒; 磁性粒子的平均粒径在10nm以上至1000nm以下的范围。
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公开(公告)号：US20090148346A1
公开(公告)日：2009-06-11
申请号：US12065720
申请日：2006-10-03
申请人： Kazuhiro Ban , Kazumichi Nakahama , Miki Ogawa
发明人： Kazuhiro Ban , Kazumichi Nakahama , Miki Ogawa
CPC分类号： B82Y30/00 , B82Y15/00 , G01N33/54393
摘要： A structural member having a binding functional group on a substrate for binding a capturing molecule capable of capturing a target substance, characterized in that the substrate binds to one end of a polymer which includes at the other end those to which the binding functional group is bound and those to which a suppressing functional group for suppressing adsorption of biological molecules to the structural member and that the suppressing functional group is also bound to a side chain of the polymer.
摘要翻译： 一种在底物上具有结合能捕获靶物质的捕获分子的结合官能团的结构部件，其特征在于，所述底物与聚合物的一端结合，所述聚合物的另一端包含结合官能团所结合的那些 以及抑制生物分子吸附到结构构件上的抑制官能团，抑制官能团也与聚合物的侧链结合的那些。
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公开(公告)号：US20080182984A1
公开(公告)日：2008-07-31
申请号：US12019209
申请日：2008-01-24
申请人： Kazumichi Nakahama , Yukio Hanyu , Takayuki Teshima , Akira Kuriyama , Toshihiko Hiaki , Kiwamu Sue , Hayato Hattori , Hironori Yamamoto
发明人： Kazumichi Nakahama , Yukio Hanyu , Takayuki Teshima , Akira Kuriyama , Toshihiko Hiaki , Kiwamu Sue , Hayato Hattori , Hironori Yamamoto
IPC分类号： C09B47/04
CPC分类号： C09B47/06 , Y02P20/544
摘要： Provided is a method for producing a pigment, in particular, a metal phthalocyanine, in high yield and in a green process. The method has (1) a step of obtaining a solution mixture by mixing at least one type of compound serving as a raw material for a pigment with a solvent, and (2) a step of obtaining the pigment by reacting the compound while holding the solution mixture at not less than a temperature where a subcritical state or a supercritical state of the solvent occurs.
摘要翻译： 提供了以高产率和绿色方法制备颜料，特别是金属酞菁的方法。 该方法具有（1）通过将至少一种用作颜料的原料的化合物与溶剂混合来获得溶液混合物的步骤，和（2）通过使化合物同时保持而获得颜料的步骤 溶液混合物在不低于溶剂的亚临界状态或超临界状态的温度下进行。
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公开(公告)号：US20070172589A1
公开(公告)日：2007-07-26
申请号：US11609466
申请日：2006-12-12
IPC分类号： B05D7/00
CPC分类号： C09B67/0096 , C09B67/0041 , C09B67/0086 , C09D11/322
摘要： The present invention provides a method of producing a pigment dispersion, comprising the steps of: preparing a solution in which two or more color pigments and a dispersant are dissolved in a solvent containing an aprotic organic solvent in the presence of an alkali; preparing a medium that decreases a solubility of the two or more color pigments by being added to the solution; feeding the solution and the medium to respective microchannels; and depositing the two or more color pigments by merging the solution and the medium transported through the respective microchannels.
摘要翻译： 本发明提供一种颜料分散体的制造方法，其特征在于，包括以下步骤：在碱的存在下，将两种以上的着色颜料和分散剂溶解于含有非质子性有机溶剂的溶剂中， 制备通过加入到溶液中降低两种或更多种着色颜料的溶解度的介质; 将溶液和介质输送到相应的微通道; 以及通过使溶液和通过各个微通道传送的介质合并来沉积两种或更多种着色颜料。
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35.发明授权公开(公告)号：US08513024B2
公开(公告)日：2013-08-20
申请号：US12517053
申请日：2009-02-04
申请人： Kazumichi Nakahama
发明人： Kazumichi Nakahama
IPC分类号： G01N27/00
CPC分类号： G01N33/54333
摘要： Provided is a detection method for a target substance capable of enhancing detection sensitivity and quantitative property of a magnetic biosensor, while keeping monodispersity and dispersion stability of magnetic markers, including the steps of: reacting the target substance in a sample solution with a first target substance trapping member immobilized on a sensing element and with a second target substance trapping member immobilized on a gel particle to hold the gel particle on the sensing element; adjusting a magnetic marker precursor including the gel particle and a magnetic material precursor existing in the gel particle by bringing the magnetic material precursor into contact with the gel particle; synthesizing a magnetic material from the magnetic material precursor held on the gel particle, thereby adjusting the magnetic markers; and detecting the magnetic markers with the sensing element.
摘要翻译： 本发明提供能够提高磁性生物传感器的检测灵敏度和定量性能的目标物质的检测方法，同时保持磁性标记物的单分散性和分散稳定性，包括以下步骤：将样品溶液中的目标物质与第一目标物质 固定在感测元件上的捕获构件和固定在凝胶颗粒上的第二目标物质捕获构件，以将凝胶颗粒保持在感测元件上; 通过使磁性材料前体与凝胶颗粒接触来调节包含凝胶颗粒的磁性标记前体和存在于凝胶颗粒中的磁性材料前体; 从保持在凝胶粒子上的磁性材料前体合成磁性材料，从而调整磁性标记; 并用感测元件检测磁标记。
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36.发明授权Production process of liquid composition, image forming process and image forming apparatus 有权液体组成，成像过程和成像设备的生产工艺公开(公告)号：US08163816B2
公开(公告)日：2012-04-24
申请号：US11746233
申请日：2007-05-09
CPC分类号： C09D11/54 , C09D11/322
摘要： A process for producing a liquid composition including a pigment and a stimuli-responsive dispersant, the pigment being contained in the liquid composition in a dispersed state, the process including (1) obtaining a solution dissolving the pigment in a first solvent and (2) mixing the solution with a second solvent, wherein the stimuli-responsive dispersant is contained in at least one solvent of the first and second solvents. The first solvent is an aprotic solvent. The second solvent is water or an aqueous solution.
摘要翻译： 一种制备包含颜料和刺激响应性分散剂的液体组合物的方法，所述颜料以分散状态包含在所述液体组合物中，所述方法包括（1）获得将颜料溶解在第一溶剂中的溶液和（2） 将溶液与第二溶剂混合，其中刺激响应性分散剂包含在第一和第二溶剂的至少一种溶剂中。 第一溶剂是非质子溶剂。 第二种溶剂是水或水溶液。
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公开(公告)号：US07927412B2
公开(公告)日：2011-04-19
申请号：US12175098
申请日：2008-07-17
申请人： Akira Kuriyama , Takayuki Teshima , Kazumichi Nakahama , Rie Ueno , Masatoshi Watanabe , Takeo Suga
发明人： Akira Kuriyama , Takayuki Teshima , Kazumichi Nakahama , Rie Ueno , Masatoshi Watanabe , Takeo Suga
CPC分类号： C09D11/54 , C09D11/322
摘要： A pigment ink composition has high transparency and good color characteristics such as a high OD that are not inferior to those of dyes, even though pigment particles are used, and also has good weatherability and remaining ability on the coating and printing medium surface that are inherent to pigment particles. The pigment ink composition contains pigment particles including at least needle pigment particles, a dispersant, and a solvent. The needle pigment particles have a needle shape with an aspect ratio of at least 3, an average aspect ratio of at least 5 and at most 7, an average short dimension of at least 20 nm and at most 30 nm, and a distribution of short dimension with a standard deviation of 2.0 nm or less. The needle pigment particles are covered with the dispersant.
摘要翻译： 颜料油墨组合物即使使用颜料颗粒，也具有高的透明性和良好的颜色特性，例如高的OD，它们不劣于染料，并且具有良好的耐候性和在固有的涂料和印刷介质表面上的剩余能力 到颜料颗粒。 颜料墨水组合物含有至少包含针状颜料颗粒，分散剂和溶剂的颜料颗粒。 针状颜料颗粒具有纵横比至少为3，平均长宽比为至少5且至多为7，平均短尺寸为至少20nm且至多为30nm的针状，并且分布为短 标准偏差为2.0nm以下的尺寸。 针状颜料颗粒被分散剂覆盖。
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公开(公告)号：US20100234561A1
公开(公告)日：2010-09-16
申请号：US12377972
申请日：2007-08-08
申请人： Kazumichi Nakahama
发明人： Kazumichi Nakahama
IPC分类号： C08J3/14
CPC分类号： C08J3/14
摘要： A process for producing fine particles is provided including the steps of (1) preparing a solution having a viscosity of 20 mPa·s or less at 25° C. by using a polymer and a first solvent, (2) mixing the solution with a second solvent to prepare an emulsion and (3) removing the first solvent from the emulsion to obtain fine particles containing the polymer.
摘要翻译： 提供一种微粒生产方法，包括以下步骤：（1）通过使用聚合物和第一溶剂在25℃下制备粘度为20mPa·s或更低的溶液，（2）将溶液与 第二溶剂以制备乳液和（3）从乳液中除去第一溶剂以获得含有聚合物的细颗粒。
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39.发明授权Preparation process of pigment dispersion, image forming process and image forming apparatus 失效颜料分散体的制备方法，成像工艺和成像设备公开(公告)号：US07754000B2
公开(公告)日：2010-07-13
申请号：US11670236
申请日：2007-02-01
IPC分类号： C09D11/00
CPC分类号： C09D17/003 , C09B67/0026 , C09B67/0035 , C09B67/0085 , C09D11/322
摘要： A process for preparing a pigment dispersion, which comprises mixing a first solvent composed of an organic solvent in which a pigment has been dissolved with a second solvent which lowers the solubility of the pigment in the presence of a dispersant, thereby precipitating and dispersing particles of the pigment in a mixed solvent, wherein a pigment derivative to which a hydrophobic substituent having affinity for the first solvent has been bonded is used as the pigment.
摘要翻译： 一种制备颜料分散体的方法，其包括将其中已经溶解有颜料的有机溶剂的第一溶剂与第二溶剂混合，所述第二溶剂在分散剂存在下降低颜料的溶解度，从而沉淀和分散 使用混合溶剂中的颜料作为颜料，其中将与第一溶剂具有亲和性的疏水性取代基结合的颜料衍生物用作颜料。
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公开(公告)号：US20090020043A1
公开(公告)日：2009-01-22
申请号：US12174052
申请日：2008-07-16
IPC分类号： C09B48/00
CPC分类号： C09B48/00 , C09B67/0096
摘要： A method for manufacturing a dispersion of a quinoline derivative that is dispersed at a high concentration and has a small particle size. The method includes the steps of preparing a solution by dissolving an N-arylanthranilic acid derivative in an organosulfonic acid, heating the solution and obtaining a reaction liquid in which a quinoline derivative has been produced by a condensation ring-closing reaction, and obtaining a dispersion of the quinoline derivative by mixing the reaction liquid with an aqueous solution. The step of mixing the reaction liquid with an aqueous solution may be performed in a mixing field having a micro-channel.
摘要翻译： 制造分散在高浓度且粒径小的喹啉衍生物的分散体的方法。 该方法包括以下步骤：通过将N-芳基邻氨基苯甲酸衍生物溶解在有机磺酸中，加热该溶液并获得通过缩合闭环反应产生喹啉衍生物的反应液，得到分散体 的喹啉衍生物通过将反应液与水溶液混合。 将反应液与水溶液混合的步骤可以在具有微通道的混合场中进行。
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