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公开(公告)号:US07029693B2
公开(公告)日:2006-04-18
申请号:US09946889
申请日:2001-09-05
CPC分类号: A61K9/7061
摘要: A percutaneously absorptive preparation is provided, which preparation having a support and an adhesive layer having a release-controlling layer, which is formed at least on one side of the support, wherein the adhesive layer contains an adhesive and 0.5–60 wt % of a drug except 1,2-ethanediol derivatives.
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公开(公告)号:US20060034900A1
公开(公告)日:2006-02-16
申请号:US11196935
申请日:2005-08-04
申请人: Yuji Saeki , Masato Nishimura , Kensuke Matsuoka , Takateru Muraoka , Yoshifumi Hosaka , Mitsuhiko Hori , Kazuhisa Ninomiya , Hitoshi Akemi , Hidetoshi Kuroda
发明人: Yuji Saeki , Masato Nishimura , Kensuke Matsuoka , Takateru Muraoka , Yoshifumi Hosaka , Mitsuhiko Hori , Kazuhisa Ninomiya , Hitoshi Akemi , Hidetoshi Kuroda
IPC分类号: A61K31/445 , A61F13/02
CPC分类号: A61K9/7053 , A61K31/4468
摘要: The present invention provides a Fentanyl-containing percutaneously absorbable adhesive preparation, which is obtained from economic starting materials, has a constitution simpler than that of conventional ones, has sufficient skin permeability, and which permits control of skin permeability by changing the mixing ratio of two kinds of polyisobutylene having different molecular weights, a tackifier and an organic liquid. Specifically, the present invention provides a percutaneously absorbable adhesive preparation comprising a support and an adhesive layer laminated on one surface thereof, wherein the adhesive layer comprises Fentanyl, two kinds of polyisobutylene having different molecular weights, a tackifier and an organic liquid compatible with the aforementioned two kinds of polyisobutylene and the aforementioned tackifier.
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