公开(公告)号：US08683822B2

公开(公告)日：2014-04-01

申请号：US12375914

申请日：2007-08-16

申请人： Byeong-Gyu Kang ,  Young-Woo Kim ,  Jae-Youl Lee ,  Hwal-Kyun Lee ,  Jong-Seok Yoon ,  Sang-Ho Park

发明人： Byeong-Gyu Kang ,  Young-Woo Kim ,  Jae-Youl Lee ,  Hwal-Kyun Lee ,  Jong-Seok Yoon ,  Sang-Ho Park

IPC分类号： F25C5/18 ,  F25D23/04 ,  F25D23/08

CPC分类号： F25C1/04 ,  F25C5/06 ,  F25C5/182 ,  F25C2305/022 ,  F25C2400/06 ,  F25C2400/10 ,  F25C2400/14 ,  F25D23/025 ,  F25D2323/023 ,  F25D2323/122 ,  F25D2400/06

摘要： A refrigerator includes a freezing chamber door provided with an ice-making assembly. Ice made by the ice-making assembly can be immediately drawn out to the outside by opening an exclusively used home-bar door. In addition, an ice-making case is coupled by a coupling formed integrally with the freezing chamber door and the ice-making case without a coupling tool or operation. Moreover, if a water bucket is installed to the ice-making case, a water supply hole of the lower end of the water bucket is opened by an opening and closing structure, so that water in the water bucket is automatically supplied to an ice tray. In addition, an ice-separating lever having a ⊂ shape is provided to simultaneously rotate a plurality of ice trays. Meanwhile, an ice bank cooperates with the home-bar door to be drawn out forward as the home-bar door is opened.

摘要翻译： 冰箱包括设有制冰组件的冷冻室门。 通过打开专门使用的家用酒吧门，可以立即将制冰装置制成的冰拉出外部。 此外，制冰盒通过与冷冻室门和制冰箱一体形成的联接器而联接，而没有联接工具或操作。 此外，如果将水桶安装在制冰箱上，则水桶下端的供水孔被打开和关闭结构打开，从而将水桶中的水自动提供给冰盘 。 此外，设置具有⊂形状的冰分离杆，以同时旋转多个冰盘。 同时，随着家庭酒吧门的打开，一个冰柜与家庭酒吧门合作向前拉出。

公开(公告)号：US08425403B2

公开(公告)日：2013-04-23

申请号：US12589444

申请日：2009-10-23

申请人： Yung-Ho Jo ,  Kwang-Gi Kim ,  Kyoung-Won Nam ,  Young-Woo Kim ,  Dong-Jun Kim

发明人： Yung-Ho Jo ,  Kwang-Gi Kim ,  Kyoung-Won Nam ,  Young-Woo Kim ,  Dong-Jun Kim

IPC分类号： A61B1/00

CPC分类号： A61B1/00147 ,  A61B1/00149

摘要： Endoscope manipulator for MIS can overcome disadvantages of multiaxial endoscope manipulator including conventional robot arm and provide compact and lightweight structure to obtain maximum activity space for medical staff. According to the endoscope manipulator for MIS, multi-joint arm is configured so that movement of all of the joints from base link to tip link is manually locked and unlocked by user and not controlled by motors. Additionally, endoscope mounted on an end of multi-joint arm is manipulated using motors to enable movement of three degrees of freedom, thereby accomplishing compact and lightweight endoscope manipulator. Additionally, tube of endoscope can be press-fitted onto tip part of multi-joint arm, and triaxial movement function for vertical, horizontal and forward/backward conveyance of endoscope is implemented in the tip part of multi-joint arm. Therefore, since external manual joints are not moved during operation, Disturbance or restriction to activities of medical staff can be minimized.

摘要翻译： 用于MIS的内窥镜操纵器可以克服包括常规机器人手臂的多轴内窥镜操纵器的缺点，并提供紧凑轻巧的结构，以获得医务人员的最大活动空间。 根据用于MIS的内窥镜操纵器，多关节臂被构造成使得所有关节从基部连杆到尖端连杆的移动由用户手动地锁定和解锁，而不是由电动机控制。 此外，使用马达来操作安装在多关节臂的端部上的内窥镜，以实现三自由度的移动，从而实现紧凑且重量轻的内窥镜操纵器。 此外，内窥镜管可以压配合到多关节臂的尖端部分，并且在多关节臂的尖端部分中实现用于内窥镜的垂直，水平和向前/向后输送的三轴运动功能。 因此，由于外部手动接头在运行过程中不能移动，因此可以尽量减少对医务人员活动的干扰或限制。

公开(公告)号：US08015839B2

公开(公告)日：2011-09-13

申请号：US11995918

申请日：2006-07-25

申请人： Byeong-Gyu Kang ,  Sung-Ho Shin ,  Young-Woo Kim ,  Jong-Suk Yoon ,  Yoon-Seok Bang ,  Jong-Wook An ,  Sang-Ho Park

发明人： Byeong-Gyu Kang ,  Sung-Ho Shin ,  Young-Woo Kim ,  Jong-Suk Yoon ,  Yoon-Seok Bang ,  Jong-Wook An ,  Sang-Ho Park

IPC分类号： F25D17/04

CPC分类号： F25D17/065 ,  F25D2317/061 ,  F25D2317/0663

摘要： The present invention relates to a cool air supply structure of a storage receptacle for a refrigerator. The present invention comprises one or more box casings detachably installed in a refrigerating chamber, each box casing having a mounting space and a channel through which cool air flows, the cool air being supplied from a cool air supply source through a cool air supply port formed in a side surface of the refrigerating chamber; and one or more storage receptacles, each storage receptacle being withdrawably installed in the mounting space, wherein food accommodated in an accommodation space provided in the storage receptacle is indirectly cooled by the cool air that flows through the channel. According to the present invention, there is an advantageous effect in that the food accommodated in a plurality of storage receptacles can be stored to be fresher by indirectly cooling the food and simultaneously the supply of cool air can be controlled depending on the use or not of the storage receptacles.

摘要翻译： 本发明涉及一种用于冰箱的储存容器的冷气供应结构。 本发明包括一个或多个可拆卸地安装在冷藏室中的盒壳体，每个箱体壳体具有安装空间和冷气流过的通道，冷空气通过形成的冷空气供应口从冷空气供应源供应 在冷藏室的侧表面中; 和一个或多个存储插座，每个存储容器可抽出地安装在安装空间中，其中容纳在设置在存储容器中的容纳空间中的食物被流过通道的冷空气间接冷却。 根据本发明，有利的效果在于，容纳在多个储存容器中的食物可以通过间接冷却食物而被储存以更新鲜，并且可以根据使用情况来控制冷空气的供应 存放容器。

公开(公告)号：US20100274079A1

公开(公告)日：2010-10-28

申请号：US12589444

申请日：2009-10-23

申请人： Kwang-Gi Kim ,  Kyoung-Won Nam ,  Yung-Ho Jo ,  Young-Woo Kim ,  Dong-Jun Kim

发明人： Kwang-Gi Kim ,  Kyoung-Won Nam ,  Yung-Ho Jo ,  Young-Woo Kim ,  Dong-Jun Kim

IPC分类号： A61B1/00

CPC分类号： A61B1/00147 ,  A61B1/00149

摘要： Endoscope manipulator for MIS can overcome disadvantages of multiaxial endoscope manipulator including conventional robot arm and provide compact and lightweight structure to obtain maximum activity space for medical staff. According to the endoscope manipulator for MIS, multi-joint arm is configured so that movement of all of the joints from base link to tip link is manually locked and unlocked by user and not controlled by motors. Additionally, endoscope mounted on an end of multi-joint arm is manipulated using motors to enable movement of three degrees of freedom, thereby accomplishing compact and lightweight endoscope manipulator. Additionally, tube of endoscope can be press-fitted onto tip part of multi-joint arm, and triaxial movement function for vertical, horizontal and forward/backward conveyance of endoscope is implemented in the tip part of multi-joint arm. Therefore, since external manual joints are not moved during operation, Disturbance or restriction to activities of medical staff can be minimized.

摘要翻译： 用于MIS的内窥镜操纵器可以克服包括常规机器人手臂的多轴内窥镜操纵器的缺点，并提供紧凑轻巧的结构，以获得医务人员的最大活动空间。 根据用于MIS的内窥镜操纵器，多关节臂被构造成使得所有关节从基部连杆到尖端连杆的移动由用户手动地锁定和解锁，而不是由电动机控制。 此外，使用马达来操作安装在多关节臂的端部上的内窥镜，以实现三自由度的移动，从而实现紧凑且重量轻的内窥镜操纵器。 此外，内窥镜管可以压配合到多关节臂的尖端部分，并且在多关节臂的尖端部分中实现用于内窥镜的垂直，水平和向前/向后输送的三轴运动功能。 因此，由于外部手动接头在运行过程中不能移动，因此可以尽量减少对医务人员活动的干扰或限制。

公开(公告)号：US07572919B2

公开(公告)日：2009-08-11

申请号：US11212229

申请日：2005-08-26

申请人： Robert W. Brueggemeier ,  Young-Woo Kim ,  John C. Hackett

发明人： Robert W. Brueggemeier ,  Young-Woo Kim ,  John C. Hackett

IPC分类号： C07D311/04 ,  C07D311/74 ,  C07D401/02

CPC分类号： C07D311/04 ,  C07D405/12

摘要： Compounds and methods useful for treating and prevention of cancer, particularly hormone-dependent breast cancer. Provided are compounds of formula I: wherein X is selected from O, N, S, SO, SO2, and S(CH2)n, wherein n=1-10; R1 and R2 may be the same or different and are selected from H, OH, OCH3, OCH2CH3, OCH2C6H5, NH2, NHCH3, N(CH3)2, CH3, CH2CH3, CH2CH2CH3, CH(CH3)2, C(CH3)3, NO2, F, Cl, Br, CF3, SH, SCH3, SCH2CH3, OCOCH3, OCOC(CH3)3, OCOCH2COOH, and CN; and R3 is a nitrogen-containing heterocyclic ring. Also provided are method for treating or preventing cancer in a subject by administering a therapeutically effective amount of a heteroaryl-containing isoflavone, or a pharmaceutically acceptable salt or prodrug thereof, to a subject in need of treatment. Also provided is a method for the synthesis of 2-substituted isoflavones by first reacting deoxybenzoins with a phase transfer catalyst to provide a 2-(alkylthio)isoflavone; second deprotecting the 2-(alkylthio)isoflavone; and third applying selective debenzylation to form the final compound.

摘要翻译： 用于治疗和预防癌症，特别是激素依赖性乳腺癌的化合物和方法。 提供式I化合物：其中X选自O，N，S，SO，SO 2和S（CH 2）n，其中n = 1-10; R1和R2可以相同或不同，选自H，OH，OCH3，OCH2CH3，OCH2C6H5，NH2，NHCH3，N（CH3）2，CH3，CH2CH3，CH2CH2CH3，CH（CH3）2，C（CH3）3 ，NO 2，F，Cl，Br，CF 3，SH，SCH 3，SCH 2 CH 3，OCOCH 3，OCOC（CH 3）3，OCOCH 2 COOH和CN; R3为含氮杂环。 还提供了通过向需要治疗的受试者施用治疗有效量的含杂芳基的异黄酮或其药学上可接受的盐或前药来治疗或预防受试者的癌症的方法。 还提供了通过首先使脱氧苯偶姻与相转移催化剂反应以提供2-（烷硫基）异黄酮来合成2-取代的异黄酮的方法; 第二次脱保护2-（烷硫基）异黄酮; 并且第三次施加选择性脱苄基以形成最终化合物。

公开(公告)号：US20090173100A1

公开(公告)日：2009-07-09

申请号：US12282676

申请日：2007-03-13

申请人： Byeong-Gyu Kang ,  Young-Woo Kim ,  Jong-Suk Yoon ,  Yoon-Seok Bang ,  Jong-Wook An ,  Sang-Ho Park

发明人： Byeong-Gyu Kang ,  Young-Woo Kim ,  Jong-Suk Yoon ,  Yoon-Seok Bang ,  Jong-Wook An ,  Sang-Ho Park

IPC分类号： F25D17/04 ,  F25D23/02 ,  F25D11/02

CPC分类号： F25D25/025 ,  F25D17/08

摘要： A cool air supply structure of a storage receptacle for a refrigerator, which includes a main body having a storage space provided therein and a door for selectively opening or closing the storage space, the cool air supply structure, comprising: one or more receptacle casings detachably installed into the storage space and having a mounting space provided therein so that a storage receptacle is moved into or out of the mounting space; and a channel provided in each of the receptacle casings so that cool air flows in the channel, wherein food received in the storage receptacle is indirectly cooled by the cool air flowing in the channel. According to the present invention, the food received in the storage receptacle of a refrigerator can be kept fresh with a simple configuration.

摘要翻译： 一种用于冰箱的存储容器的冷空气供应结构，其包括设置在其中的存储空间的主体和用于选择性地打开或关闭存储空间的门，所述冷气供应结构包括：可拆卸地安装一个或多个插座壳体 安装在存储空间中并具有设置在其中的安装空间，使得存储容器移入或移出安装空间; 以及设置在每个插座壳体中的通道，使得冷空气在通道中流动，其中容纳在存储容器中的食物被在通道中流动的冷空气间接地冷却。 根据本发明，容纳在冰箱的储存容器中的食品可以以简单的结构保持新鲜。

公开(公告)号：US20080196440A1

公开(公告)日：2008-08-21

申请号：US11995918

申请日：2006-07-25

申请人： Byeong-Gyu Kang ,  Sung-Ho Shin ,  Young-Woo Kim ,  Jong-Suk Yoon ,  Yoon-Seok Bang ,  Jong-Wook An ,  Sang-Ho Park

发明人： Byeong-Gyu Kang ,  Sung-Ho Shin ,  Young-Woo Kim ,  Jong-Suk Yoon ,  Yoon-Seok Bang ,  Jong-Wook An ,  Sang-Ho Park

IPC分类号： F25D17/08 ,  F25D17/00 ,  F25D17/06

CPC分类号： F25D17/065 ,  F25D2317/061 ,  F25D2317/0663

摘要： The present invention relates to a cool air supply structure of a storage receptacle for a refrigerator. The present invention comprises one or more box casings detachably installed in a refrigerating chamber, each box casing having a mounting space and a channel through which cool air flows, the cool air being supplied from a cool air supply source through a cool air supply port formed in a side surface of the refrigerating chamber; and one or more storage receptacles, each storage receptacle being withdrawably installed in the mounting space, wherein food accommodated in an accommodation space provided in the storage receptacle is indirectly cooled by the cool air that flows through the channel. According to the present invention, there is an advantageous effect in that the food accommodated in a plurality of storage receptacles can be stored to be fresher by indirectly cooling the food and simultaneously the supply of cool air can be controlled depending on the use or not of the storage receptacles.

摘要翻译： 本发明涉及一种用于冰箱的储存容器的冷气供应结构。 本发明包括一个或多个可拆卸地安装在冷藏室中的盒壳体，每个箱体壳体具有安装空间和冷气流过的通道，冷空气通过形成的冷空气供应口从冷空气供应源供应 在冷藏室的侧表面中; 和一个或多个存储插座，每个存储容器可抽出地安装在安装空间中，其中容纳在设置在存储容器中的容纳空间中的食物被流过通道的冷空气间接冷却。 根据本发明，有利的效果在于，容纳在多个储存容器中的食物可以通过间接冷却食物而被储存以更新鲜，并且可以根据使用情况来控制冷空气的供应 存放容器。

公开(公告)号：US20080058776A1

公开(公告)日：2008-03-06

申请号：US11515738

申请日：2006-09-06

申请人： Yung-Ho Jo ,  Dong-Jun Kim ,  Jaesoon Choi ,  Jae-Gahb Park ,  Young-Woo Kim ,  Sang-Jae Park

发明人： Yung-Ho Jo ,  Dong-Jun Kim ,  Jaesoon Choi ,  Jae-Gahb Park ,  Young-Woo Kim ,  Sang-Jae Park

IPC分类号： A61B17/00

CPC分类号： A61B34/70 ,  A61B34/30 ,  A61B34/37 ,  A61B2034/305

摘要： A robotic surgical system includes a master manipulator, slave robotic units having a surgical instrument for performing a Minimal Invasive Surgery (MIS), and a control system for electrically associating the master manipulator with the slave robotic units. The slave robotic unit includes the driving mechanisms which are more compact than those of the conventional MIS system. In use, the existing surgical instruments used in the conventional MIS procedure can be applied to the slave robotic unit. Moreover, by using the pivotal mechanism of the driving mechanisms, a pivot point of the surgical instrument is allowed to be shifted with respect to an incision of a patient. So, the patient's tissues surrounding the surgical instrument are not excessively affected by the surgical instrument during the procedure.

摘要翻译： 机器人手术系统包括主操纵器，具有用于执行微创手术（MIS）的手术器械的从属机器人单元以及用于将主操纵器与从机器人单元电联动的控制系统。 从机器人单元包括比常规MIS系统更紧凑的驱动机构。 在使用中，常规MIS程序中使用的现有手术器械可以应用于从动机器人单元。 此外，通过使用驱动机构的枢转机构，允许手术器械的枢转点相对于患者的切口移动。 因此，手术器械周围的患者组织不会被手术器械过度影响。

公开(公告)号：US07105542B2

公开(公告)日：2006-09-12

申请号：US10634463

申请日：2003-08-04

申请人： Robert W. Brueggemeier ,  Young-Woo Kim

发明人： Robert W. Brueggemeier ,  Young-Woo Kim

IPC分类号： A61K31/445 ,  C07D405/10

CPC分类号： C07D311/56

摘要： The present invention provides 2-heterosubstituted 3-aryl-4H-benzopyran-4-one compounds for the treatment of cancers, namely breast cancer. This invention further provides a method of synthesis of 2-(alkylthio)isoflavones that can be carried out at ambient conditions. This invention further provides a method of synthesis of the 2-heterosubstituted 3-aryl-4H-benzopyran-4-one from a 2-(alkylthio)isoflavone. The invention further provides methods of using the 2-heterosubstituted 3-aryl-4H-benzopyran-4-one compounds for the treatment of breast cancer in mammals.

摘要翻译： 本发明提供2-异取代的3-芳基-4H-苯并吡喃-4-酮化合物，用于治疗癌症，即乳腺癌。 本发明还提供了可以在环境条件下进行的2-（烷硫基）异黄酮的合成方法。 本发明还提供了从2-（烷硫基）异黄酮合成2-取代的3-芳基-4H-苯并吡喃-4-酮的方法。 本发明还提供了使用2-异取代的3-芳基-4H-苯并吡喃-4-酮化合物治疗哺乳动物乳腺癌的方法。

公开(公告)号：US20060183923A1

公开(公告)日：2006-08-17

申请号：US11212229

申请日：2005-08-26

申请人： Robert Brueggemeier ,  Young-Woo Kim ,  John Hackett

发明人： Robert Brueggemeier ,  Young-Woo Kim ,  John Hackett

IPC分类号： C07D311/04 ,  C07D311/74

CPC分类号： C07D311/04 ,  C07D405/12

摘要： Compounds and methods useful for treating and prevention of cancer, particularly hormone-dependent breast cancer. Provided are compounds of formula I: wherein X is selected from O, N, S, SO, SO2, and S(CH2)n, wherein n=1-10; R1 and R2 may be the same or different and are selected from H, OH, OCH3, OCH2CH3, OCH2C6H5, NH2, NHCH3, N(CH3)2, CH3, CH2CH3, CH2CH2CH3, CH(CH3)2, C(CH3)3, NO2, F, Cl, Br, CF3, SH, SCH3, SCH2CH3, OCOCH3, OCOC(CH3)3, OCOCH2COOH, and CN; and R3 is a nitrogen-containing heterocyclic ring. Also provided are method for treating or preventing cancer in a subject by administering a therapeutically effective amount of a heteroaryl-containing isoflavone, or a pharmaceutically acceptable salt or prodrug thereof, to a subject in need of treatment. Also provided is a method for the synthesis of 2-substituted isoflavones by first reacting deoxybenzoins with a phase transfer catalyst to provide a 2-(alkylthio)isoflavone; second deprotecting the 2-(alkylthio)isoflavone; and third applying selective debenzylation to form the final compound.

摘要翻译： 用于治疗和预防癌症，特别是激素依赖性乳腺癌的化合物和方法。 本发明提供式I化合物：其中X选自O，N，S，SO，SO 2和S（CH 2）n ，其中n = 1-10; R 1和R 2可以相同或不同，并且选自H，OH，OCH 3，OCH 2， CH 3，CH 2，CH 2，CH 2，NH 2，CH 2， NHCH 3，N（CH 3）2，CH 3，CH 2， CH 3 CH 3，CH 2 CH 2 CH 3，CH（CH 3 CH 3） C（CH 3）3，NO 2，F，Cl，Br，CF 3， 3，SH，SCH 3，SCH 2，CH 3，OCOCH 3，OCOC（CH 3 CO 3，COCO 2，CN; R 3是含氮杂环。 还提供了通过向需要治疗的受试者施用治疗有效量的含杂芳基的异黄酮或其药学上可接受的盐或前药来治疗或预防受试者的癌症的方法。 还提供了通过首先使脱氧苯偶姻与相转移催化剂反应以提供2-（烷硫基）异黄酮来合成2-取代的异黄酮的方法; 第二次脱保护2-（烷硫基）异黄酮; 并且第三次施加选择性脱苄基以形成最终化合物。