公开(公告)号：US20210322504A1

公开(公告)日：2021-10-21

申请号：US17362707

申请日：2021-06-29

Applicant: KUWAIT UNIVERSITY

Inventor： MOHAMMAD ABDULRAHMAN ALI ALANSARI

IPC: A61K36/487 ,  A61P17/00 ,  A61K9/00 ,  A61K36/185 ,  A61K36/23 ,  A61K36/28 ,  A61K36/29 ,  A61K36/482 ,  A61N5/06

Abstract: A first embodiment of a composition for treating vitiligo includes Cassia tora powder, Saussurea lappa root powder, Punica granatum L. (pomegranate) peels powder, and Psoralea corylifolia black seed powder. A second embodiment of a composition for treating vitiligo can include Cassia tora powder, Saussurea lappa root powder, Punica granatum L. (pomegranate) peels powder, Berberries (or Berberis) vulgaris root powder, red clay (with trace copper), and Ptycholis verlicillata root powder. Topical administration of the first composition followed by UV radiation exposure can facilitate inducing melanogenesis as well as generating ROS. Topical administration of the second composition following the UV radiation exposure can scavenge the ROS generated by the first composition.

公开(公告)号：US10723694B2

公开(公告)日：2020-07-28

申请号：US16149317

申请日：2018-10-02

Applicant: KUWAIT UNIVERSITY

Inventor： Saad A. Makhseed ,  Ali A. Husain ,  Asaithampi Ganesan ,  Mahmut Durmus

IPC: C07C255/54 ,  C07F3/06 ,  A61P35/00

Abstract: Propargyl-functionalized macrocyclic compounds can include non-aggregating compounds having at least one phthalocyanine (Pc), azaphthalocyanine (AzaPc), or naphthalocyanine (Nc) unit. The compounds can be metal-free or metal-complexed. The metal-complexed compounds can include zinc (II), for example. The compounds can include multiple propargyl moieties at different sites, e.g., peripheral or non-peripheral sites, as described herein. Exemplary compounds include an azaphthalocyanine complex (AzaPc1) and phthalocyanine complexes (Pc2-Pc5). The compounds may provide efficient solubility in aqueous and/or organic solvents, optimal physicochemical properties, improved photo-sensitizability, significant tumor specificity, and electron transfer tunability. The compounds can provide suitable non-aggregated molecular scaffolds for construction of numerous macrocycle derivatives via different organic transformation methodologies, e.g., Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC).

公开(公告)号：US10087487B2

公开(公告)日：2018-10-02

申请号：US14481884

申请日：2014-09-09

Applicant: KUWAIT UNIVERSITY

Inventor： Fahd Al-Mulla ,  Jean Paul Thiery ,  Milad S. Bitar

IPC: C12P19/34 ,  C12Q1/6886

Abstract: The method for determining risk of metastatic relapse in a patient diagnosed with colorectal cancer (CRC) can include detecting a level of at least one indicator of metastatic potential in a biological sample from the patient, comparing the level of the indicator of metastatic potential with a control, and identifying the patient as one who is at risk of metastatic relapse and a candidate for chemotherapy if an aberrant level of the indicator of metastatic potential in the biological sample compared to the control is detected. The at least one indicator of metastatic potential can include at least one metastasis-inducing gene and/or at least one metastasis suppressor gene. An aberrant level of the at least one indicator of metastatic potential can include a copy number gain of the metastasis-inducing gene and/or a copy number loss of the metastasis-suppressor gene.

公开(公告)号：US10085394B2

公开(公告)日：2018-10-02

申请号：US15209536

申请日：2016-07-13

Applicant: KUWAIT UNIVERSITY

Inventor： Fawaz Shukhier Al-Anzi

IPC: A01G13/02 ,  A01G9/02 ,  A01G25/00 ,  A01G27/02 ,  A01G27/00 ,  A01G9/00

Abstract: The planter system using waste materials repurpose waste materials to construct a self-irrigating planter that promotes plant growth in a protective environment. The planter system includes a water reservoir constructed from scrap tire defining a hollow interior serving as water storage, the reservoir being buried in soil. A condensation funnel having a sloped condensation skirt extends into the center opening of the scrap tire to direct condensate into the water reservoir. A root ball cover made from scrap newspaper covers the root system of a plant, and the plant is buried in the center opening of the scrap tire. A soil protection cover is placed atop the root ball cover to protect the soil of the root ball, and a support tube extends therefrom to protect the stem of the plant from environmental conditions. A valve regulates delivery of water to the reservoir. Most components are made from scrap plastic.

公开(公告)号：US09399866B2

公开(公告)日：2016-07-26

申请号：US14183348

申请日：2014-02-18

Applicant: KUWAIT UNIVERSITY

Inventor： Esam M. Alawadhi

IPC: F28D20/02 ,  E04B9/00 ,  G01K13/00 ,  F24J2/54 ,  F24J2/34

CPC classification number: E04B9/001 ,  F24S30/40 ,  F24S60/00 ,  F28D20/02 ,  G01K13/00 ,  Y02B10/20

Abstract: A thermal barrier panel with selectable phase change materials includes a thermal panel and a plurality of containers movably positioned within the thermal panel to correspond to a heat load at a corresponding ambient temperature. Each of the plurality of containers includes a plurality of receptacles that include a plurality of different phase change materials. Each of the plurality of different phase change materials absorbs thermal energy produced by heat from the heat load at a corresponding ambient temperature. Each of the plurality of different phase change materials are positioned in a corresponding receptacle within a corresponding container, and each of the plurality of receptacles in a corresponding container include one of the plurality of different phase change materials. Corresponding ones of the plurality of receptacles are movably positioned to place a corresponding phase change material in facing relation to the heat load based upon the corresponding ambient temperature.

Abstract translation: 具有可选择的相变材料的热障板包括热面板和可移动地定位在热面板内的多个容器，以对应于相应环境温度下的热负荷。 多个容器中的每一个包括多个容纳件，其包括多个不同的相变材料。 多个不同的相变材料中的每一个在相应的环境温度下吸收来自热负荷的热产生的热能。 多个不同相变材料中的每一个位于相应的容器内的对应容器中，并且相应容器中的多个容器中的每一个都包括多个不同相变材料中的一个。 多个插座中的相应的插座可移动地定位成基于相应的环境温度将相应的相变材料置于与热负荷相对的面对关系中。

公开(公告)号：US20150233115A1

公开(公告)日：2015-08-20

申请号：US14183348

申请日：2014-02-18

Applicant: KUWAIT UNIVERSITY

Inventor： ESAM M. ALAWADHI

IPC: E04B9/00 ,  G01K13/00

CPC classification number: E04B9/001 ,  F24S30/40 ,  F24S60/00 ,  F28D20/02 ,  G01K13/00 ,  Y02B10/20

Abstract: A thermal barrier panel with selectable phase change materials includes a thermal panel and a plurality of containers movably positioned within the thermal panel to correspond to a heat load at a corresponding ambient temperature. Each of the plurality of containers includes a plurality of receptacles that include a plurality of different phase change materials. Each of the plurality of different phase change materials absorbs thermal energy produced by heat from the heat load at a corresponding ambient temperature. Each of the plurality of different phase change materials are positioned in a corresponding receptacle within a corresponding container, and each of the plurality of receptacles in a corresponding container include one of the plurality of different phase change materials. Corresponding ones of the plurality of receptacles are movably positioned to place a corresponding phase change material in facing relation to the heat load based upon the corresponding ambient temperature.

Abstract translation: 具有可选择的相变材料的热障板包括热面板和可移动地定位在热面板内的多个容器，以对应于相应环境温度下的热负荷。 多个容器中的每一个包括多个容纳件，其包括多个不同的相变材料。 多个不同的相变材料中的每一个在相应的环境温度下吸收来自热负荷的热产生的热能。 多个不同相变材料中的每一个位于相应的容器内的对应容器中，并且相应容器中的多个容器中的每一个都包括多个不同相变材料中的一个。 多个插座中的相应的插座可移动地定位成基于相应的环境温度将相应的相变材料置于与热负荷相对的面对关系中。

公开(公告)号：US08956168B2

公开(公告)日：2015-02-17

申请号：US13894378

申请日：2013-05-14

Applicant: Kuwait University

Inventor： Bader Shafaqa Al-Anzi

IPC: H01R13/66 ,  H01R13/635

CPC classification number: H01R13/6683 ,  H01R13/635 ,  H01R13/6666 ,  H01R13/7132 ,  H01R24/30 ,  H01R24/78 ,  H01R31/065

Abstract: The electrical outlet safety device is placed between an electrical plug and the corresponding electrical outlet or receptacle to which the plug is connected. The safety device includes a thin body portion formed of a material adapted to expand rapidly if exposed to a predetermined temperature. A series of thin, electrically and thermally conductive blades extends from the body, with the blades being captured between the prongs of the plug and the internal contacts of the receptacle when installed therewith. If excessively high electrical resistance and correspondingly high temperature are produced in one or more of the electrical connections between the plug and the outlet, the blades of the safety device transmit the excessive temperature to the body, whereupon the body is transformed to an expansive electrically insulating foam that expels the plug from the receptacle. Springs may be included within the body to provide additional expansive force.

Abstract translation: 电源插座安全装置放置在电插头和插头所连接的对应的电源插座或插座之间。 安全装置包括由适于在暴露于预定温度下快速膨胀的材料形成的薄体部分。 一系列薄，导电和导热的叶片从主体延伸，当与其一起安装时，叶片被捕获在插头的插脚和插座的内部触点之间。 如果在插头和出口之间的一个或多个电连接中产生过高的电阻和相应的高温，则安全装置的叶片将过量的温度传递到主体，于是将主体转变成膨胀的电绝缘 将插头从插座中排出的泡沫。 弹簧可以包括在体内以提供额外的膨胀力。

公开(公告)号：US08904991B2

公开(公告)日：2014-12-09

申请号：US13681297

申请日：2012-11-19

Applicant: Kuwait University

Inventor： Osamah M. Al-Hawaj

IPC: F02B53/00 ,  F01C1/44 ,  F02B55/14 ,  F04C2/44

CPC classification number: F01C1/44 ,  F01C1/22 ,  F01C21/08 ,  F02B55/14 ,  F04C2/44 ,  Y02T10/17

Abstract: The rotary mechanism with articulating rotor may be adapted as a pump or compressor when external power is applied to its shaft, as a motor when differential pressure is applied to its inlet and outlet ports, or as an internal combustion engine when provided with fuel, air, and ignition source. The mechanism includes an internal chamber having major and minor diameters. An articulating rotor having four linked segments rotates therein. The segments allow the rotor to articulate between square and rhomboid shapes as it rotates within the chamber, the rotor segments forming variable volume chamber portions as they rotate. The rotor segments are linked to the central shaft either by a transverse arm rotationally affixed to the central shaft and to diametrically opposed rotor segments, or by telescoping rods connecting the linked ends of the rotor segments to the central shaft.

Abstract translation: 具有铰接转子的旋转机构可以在外部动力施加到其轴时作为电动机适合，作为电动机，当压力施加到其入口和出口端口时，或当作为内燃机设置有燃料，空气 ，和点火源。 该机构包括具有主要和次要直径的内部腔室。 具有四个连接部分的铰接转子在其中旋转。 这些段允许转子在腔室内旋转时在正方形和菱形形状之间铰接，转子段在它们旋转时形成可变容积室部分。 转子段通过旋转地附接到中心轴和直径相对的转子段的横向臂或通过将转子段的连接端连接到中心轴的伸缩杆连接到中心轴。

公开(公告)号：US20140341856A1

公开(公告)日：2014-11-20

申请号：US13898426

申请日：2013-05-20

Applicant: KUWAIT UNIVERSITY

Inventor： NARJES H. DASHTI ,  MAGDY S. MONTASSER

IPC: A61K35/76 ,  A61K35/74

CPC classification number: A01H3/00

Abstract: The method of controlling tomato plant viruses involves inoculation of an uninfected plant with a combination of a cucumber mosaic virus (CMV-KU1) associated with a naturally occurring benign viral satellite RNA with a mixture of two plant growth-promoting rhizobacteria (PGPR) strains, namely, Pseudomonas aeruginosa and Stenotrophomonas rhizophilia, in order to protect plants from the virulent CMV virus while promoting plant growth, yield and fruit quality of the tomato that is lost due to the viral infection. The healthy plant leaves are inoculated with the CMV-KU1 virus at the dicotyledonary stage. Simultaneously, the roots of the tomato plants are inoculated with the PGPR mixture. The satellite RNA component of the combination protects plants against a virulent virus (CMV-16), while the PGPR component compensates for growth, yield, and quality loss of tomato seen in the presence of both CMV-KU1 and CMV-16, in addition to strengthening the protection of plants.

Abstract translation: 控制番茄植物病毒的方法涉及将与天然存在的良性病毒卫星RNA相关联的黄瓜花叶病毒（CMV-KU1）与两种植物生长促进的根际细菌（PGPR）菌株的混合物组合的未感染植物的接种， 即绿脓假单胞菌和嗜麦芽寡养单胞菌，以保护植物免受有毒的CMV病毒的侵害，同时促进由于病毒感染而损失的番茄的植物生长，产量和果实质量。 在双子叶阶段，将健康植物叶接种CMV-KU1病毒。 同时，用PGPR混合物接种番茄植物的根。 该组合的卫星RNA组分保护植物免受有毒的病毒（CMV-16），而PGPR组分补偿了在存在CMV-KU1和CMV-16的情况下观察到的番茄的生长，产量和质量损失，另外 加强对植物的保护。

公开(公告)号：US08668900B2

公开(公告)日：2014-03-11

申请号：US13028047

申请日：2011-02-15

Applicant: Fatma Jassab Faleh Marzooq Al-Saeedi

Inventor： Fatma Jassab Faleh Marzooq Al-Saeedi

IPC: A61K51/04 ,  A61K51/00

CPC classification number: A61K51/0406 ,  C07F13/005

Abstract: The cancer-imaging agent and method of radioimaging relates to the use of a radioimaging agent for the imaging increased choline uptake to detect cancerous tissue. The radioimaging agent includes choline or a pharmaceutically acceptable salt thereof labeled with technetium-99m. Preferably, the radioimaging agent is [methyl]-choline chloride labeled with 99mTcO4, which carries technetium-99m. In use, a patient is administered an effective amount of the radioimaging agent by injection and then scanned with a radioimaging device. The radioimaging agent is used to image select soft tissues in the patient, such as the liver or gallbladder, the upper abdominal organs, or the like, and to detect increased choline uptake. Choline is known to accumulate in cancerous cells. Thus, the radioimaging agent is particularly effective in the detection of potentially cancerous tissues.

Abstract translation: 癌症成像剂和放射成像方法涉及放射成像剂用于成像增加胆碱摄取以检测癌组织的用途。 放射成像剂包括用锝-99m标记的胆碱或其药学上可接受的盐。 优选地，放射成像剂是用99mTcO4标记的[甲基] - 胆碱氯化物，其携带锝-99m。 在使用中，患者通过注射施用有效量的放射成像剂，然后用放射成像装置进行扫描。 放射成像剂用于对患者中的软组织（例如肝或胆囊，上腹部器官等）成像，并检测胆碱摄取增加。 已知胆碱在癌细胞中积累。 因此，放射成像剂在潜在的癌组织的检测中特别有效。