公开(公告)号：US20210369349A1

公开(公告)日：2021-12-02

申请号：US17399969

申请日：2021-08-11

Applicant: Board of Regents of the University of Nebraska

Inventor： Hani Haider ,  Osvaldo Andres Barrera

IPC: A61B34/10 ,  A61B17/14 ,  A61B90/00 ,  A61B34/20 ,  A61B34/30 ,  A61B90/11 ,  A61B17/15 ,  A61B17/16 ,  A61B17/17

Abstract: A number of improvements are provided relating to computer aided surgery. The improvement relates to both the methods used during computer aided surgery and the devices used during such procedures. Some of the improvement relate to controlling the selection of which data to display during a procedure and/or how the data is displayed to aid the surgeon. Other improvements relate to the structure of the tools used during a procedure and how the tools can be controlled automatically to improve the efficiency of the procedure. Still other improvements relate to methods of providing feedback during a procedure to improve either the efficiency or quality, or both, for a procedure.

公开(公告)号：US20210338349A1

公开(公告)日：2021-11-04

申请号：US17368023

申请日：2021-07-06

Applicant: Board of Regents of the University of Nebraska

Inventor： Shane Farritor ,  Erik Mumm ,  Philip Chu ,  Nishant Kumar ,  Jason Dumpert ,  Yutaka Tsutano

IPC: A61B34/30 ,  A61B17/29 ,  A61B34/37 ,  A61B17/00 ,  A61B34/00 ,  A61B90/30 ,  A61B90/00

Abstract: The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various modular medical devices for in vivo medical procedures.

公开(公告)号：US11154557B2

公开(公告)日：2021-10-26

申请号：US17301030

申请日：2021-03-22

Applicant: Board of Regents of the University of Nebraska

Inventor： Howard Gendelman ,  Benson Edagwa

IPC: A61K31/535 ,  A61K31/495 ,  A61K9/50 ,  A61K31/5365 ,  A61P31/18 ,  A61K9/00 ,  A61K9/16

Abstract: The present invention provides prodrugs and methods of use thereof.

公开(公告)号：US20210307813A1

公开(公告)日：2021-10-07

申请号：US17352817

申请日：2021-06-21

Applicant: Board of Regents of the University of Nebraska

Inventor： Shane Farritor ,  Thomas Frederick ,  Joe Bartels

IPC: A61B18/14

Abstract: The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices, and more specifically including end effectors that can be incorporated into such devices. Certain end effector embodiments include various vessel cautery devices that have rotational movement as well as cautery and cutting functions while maintaining a relatively compact structure. Other end effector embodiments include various end effector devices that have more than one end effector.

公开(公告)号：US20210275535A1

公开(公告)日：2021-09-09

申请号：US17303228

申请日：2021-05-24

Applicant: Board of Regents of the University of Nebraska

Inventor： Howard Gendelman ,  Benson Edagwa

IPC: A61K31/5365 ,  A61P31/18 ,  A61K9/16 ,  A61K9/00

Abstract: The present invention provides prodrugs and methods of use thereof.

公开(公告)号：US20210254092A1

公开(公告)日：2021-08-19

申请号：US17169444

申请日：2021-02-06

Applicant: Jan Christer Lofstedt ,  Per Fredrik Hofvander ,  Honglei Wang ,  Baojian Ding ,  Yihan Xia ,  Carin Ingegerd Jarl-Sunesson ,  Board of Regents of the University of Nebraska ,  ISCA Technologies, Inc.

Inventor： Jan Christer Lofstedt ,  Per Fredrik Hofvander ,  Baojian Ding ,  Yihan Xia ,  Honglei Wang ,  Carin Ingegerd Jarl-Sunesson ,  Edgar Benjamin Cahoon ,  Agenor Mafra-Neto

IPC: C12N15/82

Abstract: The present disclosure relates to methods of producing insect pheromone precursors and genetically modified plants capable of producing insect pheromone precursors. The genetically modified plants include a heterologous gene encoding at least one silencing suppressor protein and at least one enzyme selected from the group consisting of a fatty acyl desaturase, a fatty acyl elongase, a fatty acyl reductase, and an acyl-CoA oxidase.

公开(公告)号：US20210236218A1

公开(公告)日：2021-08-05

申请号：US17236489

申请日：2021-04-21

Applicant: Board of Regents of the University of Nebraska

Inventor： Joseph Palmowski ,  Shane Farritor

IPC: A61B34/30 ,  B25J17/02 ,  B25J9/12 ,  B25J9/10

Abstract: Disclosed herein are various robotic surgical devices and systems that include first and second elongate bodies, first and second driveshafts disposed through the second elongate body, and an in-line shoulder joint with a robotic arm coupled thereto. In certain implementations, the in-line shoulder joint has a differential yoke and a dual shaft disposed within the yoke lumen.

公开(公告)号：US20210228747A1

公开(公告)日：2021-07-29

申请号：US16967527

申请日：2019-04-04

Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA

Inventor： Janina Baranowska-Kortylewicz ,  Zbigniew Kortylewicz

IPC: A61K51/04 ,  A61P35/00 ,  C07D235/32 ,  A61K31/4184 ,  A61N5/10 ,  A61B6/03

Abstract: Compositions and methods for treating, detecting, and diagnosing cancer are disclosed.

公开(公告)号：US11051895B2

公开(公告)日：2021-07-06

申请号：US16689326

申请日：2019-11-20

Applicant: Board of Regents of the University of Nebraska

Inventor： Shane Farritor ,  Erik Mumm ,  Philip Chu ,  Nishant Kumar ,  Jason Dumpert ,  Yutaka Tsutano

IPC: A61B34/30 ,  A61B17/00 ,  A61B34/00 ,  A61B17/29 ,  A61B34/37 ,  A61B90/30 ,  A61B90/00

Abstract: The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various modular medical devices for in vivo medical procedures.

公开(公告)号：US11033560B2

公开(公告)日：2021-06-15

申请号：US16605564

申请日：2018-04-25

Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA ,  UNIVERSITY OF IOWA RESEARCH FOUNDATION

Inventor： Sarah Holstein ,  David Wiemer

IPC: A61K31/683 ,  A61K45/06 ,  C07F9/6518

Abstract: Disclosed herein are inhibitors of the GGDPS enzyme, and methods for their use in treating or preventing diseases, such as multiple myeloma. The inhibitors described herein can include compounds of Formula (I) and pharmaceutically acceptable salts thereof: wherein the substituents are described.