Abstract:
The present invention relates to 3,4-substituted piperidinyl-based renin inhibitor compounds bearing at 4-position oxopyridine and having the formula (I). The invention further relates to pharmaceutical compositions containing said compounds, as well as their use in treating cardiovascular events and renal insufficiency.
Abstract:
A feed mechanism of mold includes a top plate, an injection body and two slides. The top plate defines a recess in the bottom for receiving the two slides. The injection body is disposed in the top of the top plate and defines a sprue at the top thereof, a first pouring runner and a second runner both connecting with the sprue. The bottom of the first pouring runner penetrates through the injection body. The slide has a mating surface. The two mating surfaces of the two slides match each other. A shaping recess is defined between the mating surfaces for receiving a core insert. An injection runner is defined between the mating surfaces and connects with the first pouring runner to define a first runner. Two molding cavities are defined among the slides, the core insert and the injection body and connect with the first runner and the second runner respectively.
Abstract:
A mold with unloading mechanism includes an upper insert embedded in an upper plate, a lower insert embedded in a lower plate and matching the upper insert to define a cavity therebetween for molding the product, a bottom clamping plate located under the lower plate via a padding plate, a pusher penetrating through the bottom clamping plate to push an ejector plate assembly movably received in the padding plate, two unloading pins, a stroke pin and an elastic element. The bottom of the unloading pin is fixed in the ejector plate assembly and the bottom of the stroke pin is movably configured in the ejector plate assembly. The top of the unloading pin and the stroke pin movably penetrates through the lower plate and the lower insert to push the product. The elastic element is against the bottom clamping plate and the bottom of the stroke pin.
Abstract:
The injection mold with a tie bar includes an upper stationary board, a stripping plate, a female board, a male board and a lower stationary plate from top to bottom. The upper stationary plate extends outward to form a projection plate, an accepting hole opened in the projection plate and having a step therein. A tie bar is arranged on the outside of the injection mold and includes a stud, a connecting head and a pole. The stud passes through the accepting hole and is fixed on the top of the pole. The stud is slidable along the accepting hole and against the step. The top of the pole is located the outside of the stripping plate while the bottom extends outward to form at least one block. The connecting head has a gap for encircling the pole and is slidable along the pole and against the block of the pole.
Abstract:
An angular ejector mechanism for ejecting a plastic article with a recess in an inner side includes an angular ejector pin, a sliding pin, an elastic elements and a stopping block. The angular ejector pin includes a molding plate and a supporting plate. A moving hole and a sliding groove are respectively defined in a front face and an opposite rear face of the molding plate to communicate with each other. The sliding pin has a stopping protrusion dividing the sliding pin into a moving portion and a sliding portion. A sliding channel is defined on a front face of the stopping block. The sliding includes a vertical channel and a inclined channel. The moving portion is received in the moving hole of the molding plate, and the sliding portion slides from the sliding channel into the inclined channel until the angular ejector pin separates from the plastic article.
Abstract:
A slide having a fixing mechanism of a slide insert includes a slide body, a slide insert and a slide core. The slide body has a connecting portion and an inserting portion. The connecting portion defines a locating hole which stretches through the top surface to bottom surface of the connection portion. The inserting portion defines an inserting hole passing through the front and back surface of the inserting portion. A core hole is defined at the junction of the connecting portion and the inserting portion. The slide insert is located in the inserting hole. One end of the slide insert protrudes around to form a preventing part. The slide core is inserted in the core hole to fix the preventing part between the back surface of the inserting portion and the slide core. Then the slide insert is fixed in the slide.
Abstract:
An injection mold including a quick-change mold assembly has a stationary platen, a mold, a core, a spring and a plurality of blots. The stationary platen has a plurality of inserting holes defined at two side laterals and a plurality of first fixing holes defined at the said laterals besides a rear lateral. The mold has a chamber, a plurality of inserting apertures and second fixing holes. The inserting apertures are corresponding to the inserting holes. The second fixing holes are corresponding to the first fixing holes. The core is placed in the chamber of the mold. The springs are located in the inserting apertures. A plurality of bolts used for anchoring the mold and the core to the stationary platen are located in the first fixing hole and the second fixing hole.
Abstract:
A side-action mechanism disclosed in the present invention includes a slide carrier, an insert core, and a core pin engaged with the slide carrier. The slide carrier has an angular slide groove perforating through the slide carrier and an opening formed and making communication between a front surface and the bottom surface with a slide way defined on its top. The insert core which is accommodated in the angular slide groove has a secured portion and an angular insert portion extending downwards from the secured portion. The core pin has a body which is small enough to be accommodated in the opening, but long enough to protrude out of the opening. The body at one end defines a pair of ears thereof for engaging with the slide way so that the core pin can slide along the slide way.
Abstract:
The invention generally provides a method for routing data into and out of a network having a plurality of host computers corresponding to a plurality of network topologies. The method of the invention primarily comprises the steps of electing a destination host from the plurality of host computers in the network, determining an addressing methodology for the destination host in accordance with a destination topology out of the plurality of network topologies corresponding to the destination host, addressing the destination host according to the determined addressing methodology, determining a routing path corresponding to the determined addressing methodology, and routing the data to the destination host through the determined routing path. The routing path can be an inbound or an outbound routing path with respect to the network. The method according to the invention further comprises the step of defining the routing path with a host ID comprising a sequence of at least one host address corresponding to at least one of the plurality of host computers.