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公开(公告)号:US20090142800A1
公开(公告)日:2009-06-04
申请号:US11283473
申请日:2005-11-18
Applicant: David Botstein , Luc Desnoyers , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Austin L. Gurney , James Pan , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood
Inventor: David Botstein , Luc Desnoyers , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Austin L. Gurney , James Pan , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , William I. Wood
IPC: C12P21/02 , C12N15/11 , C12N15/00 , C12N5/06 , C12N9/96 , C07K16/18 , C12N9/02 , C12N1/21 , C12N1/19
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US07368558B2
公开(公告)日:2008-05-06
申请号:US10899671
申请日:2004-07-27
Applicant: David Botstein , Audrey Goddard , Paul J. Godowski , Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Margaret Ann Roy , William I. Wood
Inventor: David Botstein , Audrey Goddard , Paul J. Godowski , Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Margaret Ann Roy , William I. Wood
CPC classification number: C07K14/47 , C07K14/705
Abstract: The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Abstract translation: 本发明涉及分泌和跨膜多肽以及编码这些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞,包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子,与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号:US07189566B2
公开(公告)日:2007-03-13
申请号:US09944896
申请日:2001-08-31
Applicant: David Botstein , Audrey Goddard , Paul Godowski , J. Christopher Grimaldi , Austin Gurney , Margaret Ann Roy , William Wood
Inventor: David Botstein , Audrey Goddard , Paul Godowski , J. Christopher Grimaldi , Austin Gurney , Margaret Ann Roy , William Wood
CPC classification number: C07K14/47 , A61K38/00 , C07K14/4703 , C07K14/70578 , C07K16/18 , C07K2317/24 , C07K2319/00 , C07K2319/02
Abstract: The present invention is directed to novel polypeptides having homology to cysteine-rich secretory protein-3 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cell comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Abstract translation: 本发明涉及与富含半胱氨酸的分泌蛋白-3和编码这些多肽的核酸分子具有同源性的新型多肽。 本文还提供了包含那些核酸序列的载体和宿主细胞,包含与异源多肽序列融合的本发明多肽的嵌合多肽分子,与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号:US07189530B2
公开(公告)日:2007-03-13
申请号:US10015869
申请日:2001-12-11
Applicant: David Botstein , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Margaret Ann Roy , Colin K. Watanabe , William I. Wood
Inventor: David Botstein , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Margaret Ann Roy , Colin K. Watanabe , William I. Wood
CPC classification number: C07K14/47
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US07109318B2
公开(公告)日:2006-09-19
申请号:US09990439
申请日:2001-11-16
Applicant: David Botstein , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Margaret Ann Roy , Colin K. Watanabe , William I. Wood
Inventor: David Botstein , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Margaret Ann Roy , Colin K. Watanabe , William I. Wood
CPC classification number: C07K14/47
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Abstract translation: 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞,包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子,与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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46.
公开(公告)号:US07074592B2
公开(公告)日:2006-07-11
申请号:US09909320
申请日:2001-07-18
Applicant: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jenni P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
Inventor: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jenni P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
CPC classification number: C07K14/47
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Abstract translation: 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞,包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子,与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号:US07056736B2
公开(公告)日:2006-06-06
申请号:US09989328
申请日:2001-11-19
Applicant: Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
Inventor: Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
CPC classification number: C07K14/47
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US07026448B2
公开(公告)日:2006-04-11
申请号:US10006485
申请日:2001-12-06
Applicant: Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood
Inventor: Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood
CPC classification number: C07K14/47
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20060073546A1
公开(公告)日:2006-04-06
申请号:US10213535
申请日:2002-08-07
Applicant: David Botstein , Luc Desnoyers , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Austin Gurney , James Pan , Margaret Roy , Timothy Stewart , Daniel Tumas , Colin Watanabe , William Wood
Inventor: David Botstein , Luc Desnoyers , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Austin Gurney , James Pan , Margaret Roy , Timothy Stewart , Daniel Tumas , Colin Watanabe , William Wood
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US06974696B2
公开(公告)日:2005-12-13
申请号:US10017085
申请日:2001-10-24
Applicant: David Botstein , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Margaret Ann Roy , William I. Wood
Inventor: David Botstein , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Margaret Ann Roy , William I. Wood
IPC: C07H21/04
CPC classification number: C07H21/04
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Abstract translation: 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞,包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子,与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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