公开(公告)号：US20120087917A1

公开(公告)日：2012-04-12

申请号：US13204336

申请日：2011-08-05

Applicant: VICTORIA SMITH ,  VIVIAN E. BARRY ,  HECTOR RODRIGUEZ ,  CARLOS AURELIO GARCIA ,  SCOTT OGG ,  DEREK MARSHALL ,  MIHO OYASU ,  DONNA HIROKO TOKUOKA BIERMANN ,  PETER VAN VLASSELAER ,  ALISON KAY HOLZER ,  SCOTT ALAN MCCAULEY

Inventor： VICTORIA SMITH ,  VIVIAN E. BARRY ,  HECTOR RODRIGUEZ ,  CARLOS AURELIO GARCIA ,  SCOTT OGG ,  DEREK MARSHALL ,  MIHO OYASU ,  DONNA HIROKO TOKUOKA BIERMANN ,  PETER VAN VLASSELAER ,  ALISON KAY HOLZER ,  SCOTT ALAN MCCAULEY

IPC: A61K39/395 ,  C07K16/46 ,  G01N33/573 ,  A61P35/00 ,  C12N7/01 ,  C12N5/10 ,  C12N1/21 ,  C12N15/62 ,  C12N1/19

CPC classification number: C07K16/40 ,  A61K39/3955 ,  A61K45/06 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/30 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/77 ,  C07K2317/92 ,  C12Q1/6886 ,  G01N33/57423 ,  G01N33/57438 ,  G01N33/57484 ,  G01N2333/90633

Abstract: The present application relates to anti-LOX and anti-LOXL2 antibodies and their use in purification, diagnostic and therapeutic methods. Antibodies include monoclonal antibodies, humanized antibodies and functional fragments thereof. Anti-LOX and anti-LOXL2 antibodies can be used to identify and treat conditions such as a fibrotic condition, angiogenesis, or to prevent a transition from an epithelial cell state to a mesenchymal cell state.

Abstract translation: 本申请涉及抗LOX和抗LOXL2抗体及其在纯化，诊断和治疗方法中的应用。 抗体包括单克隆抗体，人源化抗体及其功能片段。 抗LOX和抗LOXL2抗体可用于鉴定和治疗诸如纤维化病症，血管发生或预防从上皮细胞状态向间充质细胞状态的转变。

公开(公告)号：US20090053224A1

公开(公告)日：2009-02-26

申请号：US12185050

申请日：2008-08-01

Applicant: Victoria Smith ,  Scott Ogg ,  Peter Van Vlasselaer ,  Vivian E. Barry ,  Derek Marshall ,  Alison Kay Holzer ,  Hector Rodriguez ,  Miho Oyasu ,  Scott Alan McCauley ,  Carlos Aurelio Garcia ,  Donna Hiroko Tokuoka Biermann

Inventor： Victoria Smith ,  Scott Ogg ,  Peter Van Vlasselaer ,  Vivian E. Barry ,  Derek Marshall ,  Alison Kay Holzer ,  Hector Rodriguez ,  Miho Oyasu ,  Scott Alan McCauley ,  Carlos Aurelio Garcia ,  Donna Hiroko Tokuoka Biermann

IPC: A61K39/395 ,  C07K16/00 ,  G01N33/53 ,  C12N9/99 ,  C12N5/00 ,  A61P35/00 ,  A61P9/00

CPC classification number: C07K16/40 ,  A61K39/3955 ,  A61K45/06 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/30 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/76 ,  C07K2317/77 ,  C07K2317/92 ,  C12Q1/6886 ,  G01N33/57423 ,  G01N33/57438 ,  G01N33/57484 ,  G01N2333/90633

Abstract: The present application relates to anti-LOX and anti-LOXL2 antibodies and their use in purification, diagnostic and therapeutic methods. Antibodies include monoclonal antibodies, humanized antibodies and functional fragments thereof. Anti-LOX and anti-LOXL2 antibodies can be used to identify and treat conditions such as a fibrotic condition, angiogenesis, or to prevent a transition from an epithelial cell state to a mesenchymal cell state.

Abstract translation: 本申请涉及抗LOX和抗LOXL2抗体及其在纯化，诊断和治疗方法中的应用。 抗体包括单克隆抗体，人源化抗体及其功能片段。 抗LOX和抗LOXL2抗体可用于鉴定和治疗诸如纤维化病症，血管发生或预防从上皮细胞状态向间充质细胞状态的转变。

公开(公告)号：USD564040S1

公开(公告)日：2008-03-11

申请号：US29285303

申请日：2007-03-27

Applicant: Mark Kurth ,  Earle Cramer ,  Hector Rodriguez ,  Charles Hartlaub

Designer： Mark Kurth ,  Earle Cramer ,  Hector Rodriguez ,  Charles Hartlaub

公开(公告)号：US20060220330A1

公开(公告)日：2006-10-05

申请号：US11267977

申请日：2005-11-07

Applicant: Carlos Urquidi ,  Hector Rodriguez

Inventor： Carlos Urquidi ,  Hector Rodriguez

IPC: B60G7/00 ,  B60G3/04

CPC classification number: F16F1/38 ,  B60G7/02 ,  B60G17/01933 ,  B60G2200/142 ,  B60G2204/11 ,  B60G2204/116 ,  B60G2204/143 ,  B60G2204/41 ,  B60G2204/41042 ,  B60G2400/05162 ,  B60G2400/052 ,  B60G2400/202 ,  B60G2400/252 ,  B60G2401/172 ,  F16F2230/08

Abstract: A bushing assembly adapted for application in vehicle suspension systems includes an embedded position sensor and an embedded speed sensor.

Abstract translation: 适用于车辆悬架系统的衬套组件包括嵌入位置传感器和嵌入式速度传感器。

公开(公告)号：US20050052277A1

公开(公告)日：2005-03-10

申请号：US10657389

申请日：2003-09-08

Applicant: Hector Rodriguez ,  Robert Newman

Inventor： Hector Rodriguez ,  Robert Newman

IPC: G07C9/00 ,  H04Q1/00

CPC classification number: G07C9/00309 ,  G07C2009/00793

Abstract: A dual purpose key fob has manipulable keys for, in a normal mode, locking and unlocking a vehicle and keys for opening a vehicle trunk and activating a panic alarm and, in a training mode, for sending code signals to tire pressure sensors to tell the sensors what tire they are in, e.g., after wheel rotation, so that the sensors subsequently can transmit the proper location signals to the vehicle's ECM along with the pressure signals.

Abstract translation: 双用途钥匙扣具有可操纵的键，用于在正常模式下锁定和解锁车辆，以及用于打开车辆行李箱并启动紧急警报的钥匙，并且在训练模式中，向码头传感器发送代码信号以告知 传感器轮胎的轮廓，例如在车轮旋转后，传感器随后可以将压力信号与适当的位置信号一起发送到车辆的ECM。