公开(公告)号：USD838100S1

公开(公告)日：2019-01-15

申请号：US29653480

申请日：2018-06-15

Applicant: Xiao-Qin Wang

Designer： Xiao-Qin Wang

公开(公告)号：US20130210750A1

公开(公告)日：2013-08-15

申请号：US13814689

申请日：2011-09-09

Applicant: Hui Wang ,  Tao Li ,  Qin Wang ,  Wei Tu ,  Xiaojun Hou

Inventor： Hui Wang ,  Tao Li ,  Qin Wang ,  Wei Tu ,  Xiaojun Hou

IPC: C07K7/08

CPC classification number: C07K7/08 ,  A61K38/00 ,  C07K14/25 ,  Y02A50/471 ,  Y02A50/473 ,  Y02A50/475

Abstract: The present invention provides a polypeptide TF1 for inhibiting type-2 Shiga-toxin activity, an encoding gene for the same and use thereof. The present polypeptide is named TF1 (also known as P1); its amino acid sequence is shown in Sequence 1 in the sequence list. The polypeptide P1 can be prepared into medicine for preventing and/or treating diseases caused by type-2 Shiga toxin or the pathogens which produce type-2 Shiga toxin.

Abstract translation: 本发明提供了用于抑制2型志贺毒素活性的多肽TF1，其编码基因及其应用。 本发明多肽称为TF1（也称为P1）; 其氨基酸序列显示在序列表中的序列1中。 多肽P1可以制备成用于预防和/或治疗由2型志贺毒素引起的疾病或产生2型志贺毒素的病原体的药物。

公开(公告)号：US20090202452A1

公开(公告)日：2009-08-13

申请号：US12272257

申请日：2008-11-17

Applicant: Richard Scott Robinson ,  Richard J. Sullivan ,  Michael Prencipe ,  Rajnish Kohli ,  Isabelle Van Rycke ,  Richard Lovell ,  Sergio Leite ,  Eric A. Simon ,  Ralph Peter Santarpia, III ,  Diane Cummins ,  Sarita V. Mello ,  Suman Chopra ,  Karen J. DePierro ,  Lynette Zaidel ,  Constantina Christopoulou ,  Ravi Subramanyam ,  Donghui Wu ,  Andre M. Morgan ,  Qin Wang ,  Gary Edward Tambs ,  Virginia Monsul Barnes

Inventor： Richard Scott Robinson ,  Richard J. Sullivan ,  Michael Prencipe ,  Rajnish Kohli ,  Isabelle Van Rycke ,  Richard Lovell ,  Sergio Leite ,  Eric A. Simon ,  Ralph Peter Santarpia, III ,  Diane Cummins ,  Sarita V. Mello ,  Suman Chopra ,  Karen J. DePierro ,  Lynette Zaidel ,  Constantina Christopoulou ,  Ravi Subramanyam ,  Donghui Wu ,  Andre M. Morgan ,  Qin Wang ,  Gary Edward Tambs ,  Virginia Monsul Barnes

IPC: A61K8/66 ,  A61K8/44 ,  A61K8/97 ,  A61Q11/00 ,  A61P31/04 ,  A61K8/21

CPC classification number: A61K8/25 ,  A61K8/44 ,  A61K2800/28 ,  A61K2800/412 ,  A61K2800/88 ,  A61Q11/00

Abstract: The invention includes methods of cleaning an oral surface, maintaining oral health and/or increasing oral health. Such methods encompass contacting an oral surface with a primary oral care composition at least once daily, contacting the oral surface with a periodic oral care maintenance composition at least once monthly, wherein the periodic oral care maintenance composition comprises a basic amino acid, in free or salt form and optionally contacting the oral surface with a periodic oral care cleaning composition at least once monthly. The periodic oral care cleaning compositions suitable for use in the method comprise an abrasive system.

Abstract translation: 本发明包括清洁口腔表面，维持口腔健康和/或增加口腔健康的方法。 这样的方法包括每天至少一次使口腔表面与主要口腔护理组合物接触，使口腔表面与定期的口腔护理维持组合物每月至少一次接触，其中定期口腔护理维持组合物包含游离或 任选地使口腔表面与定期的口腔护理清洁组合物每月至少一次接触。 适用于该方法的定期口腔护理清洁组合物包括研磨系统。

公开(公告)号：US20090092562A1

公开(公告)日：2009-04-09

申请号：US12275361

申请日：2008-11-21

Applicant: Lynette Zaidel ,  Suman K. Chopra ,  Michael Prencipe ,  Qin Wang ,  Constantina Christopoulou

Inventor： Lynette Zaidel ,  Suman K. Chopra ,  Michael Prencipe ,  Qin Wang ,  Constantina Christopoulou

IPC: A61K8/25 ,  A61Q11/00

CPC classification number: A61K8/04 ,  A61K8/25 ,  A61K8/8164 ,  A61K2800/412 ,  A61Q11/00

Abstract: The invention includes an oral care composition that reduces and/or eliminates the perception of tooth sensitivity. The composition includes an adherent material and particles having an average particle size of about 8 microns or less. The particles are present in the composition in an amount of about 5% by weight. Also included within the scope of the invention are related methods, such as methods of occluding a dentin tubule.

Abstract translation: 本发明包括减少和/或消除牙齿敏感性感觉的口腔护理组合物。 组合物包括粘附材料和具有约8微米或更小的平均粒度的颗粒。 颗粒在组合物中的存在量为约5重量％。 也包括在本发明的范围内的是相关方法，例如封闭牙本质小管的方法。

公开(公告)号：US20070071696A1

公开(公告)日：2007-03-29

申请号：US11236094

申请日：2005-09-27

Applicant: Qin Wang ,  Suman Chopra ,  Lynette Zaidel ,  Michael Prencipe

Inventor： Qin Wang ,  Suman Chopra ,  Lynette Zaidel ,  Michael Prencipe

IPC: A61K8/42 ,  A61K8/22

CPC classification number: A61K8/22 ,  A61K8/20 ,  A61K8/21 ,  A61K8/24 ,  A61K8/25 ,  A61K8/38 ,  A61K8/737 ,  A61K8/85 ,  A61K8/86 ,  A61K8/89 ,  A61K2800/88 ,  A61Q11/00

Abstract: A dual phase whitening oral care composition comprising a first phase comprising a bound peroxide in a substantially anhydrous carrier and a second phase comprising an abrasive and a tartar control system in an orally acceptably carrier. Methods of whitening a tooth surface are also provided.

Abstract translation: 双相增白口腔护理组合物，其包含在基本上无水的载体中包含结合的过氧化物的第一相和在口服可接受的载体中包含研磨剂和牙垢控制体系的第二相。 还提供了牙齿表面美白的方法。

公开(公告)号：US20060147394A1

公开(公告)日：2006-07-06

申请号：US11285871

申请日：2005-11-23

Applicant: Ramachandra Shastry ,  Yelloji Mirajkar ,  Nagaraj Dixit ,  Ryan Cameron ,  Qin Wang ,  Lynette Zaidel ,  Suman Chopra ,  Michael Prencipe

Inventor： Ramachandra Shastry ,  Yelloji Mirajkar ,  Nagaraj Dixit ,  Ryan Cameron ,  Qin Wang ,  Lynette Zaidel ,  Suman Chopra ,  Michael Prencipe

IPC: A61K8/00

CPC classification number: A61K8/22 ,  A61K8/8152 ,  A61Q11/00

Abstract: In various embodiments, the present invention provides a tooth whitening composition comprising a peroxide composite and an orally acceptable carrier. The peroxide composite comprises a peroxide compound and a porous cross-linked polymer, preferably in the form of a microporous particulate. The peroxide compound can be sorbed onto the porous crosslinked polymer. The porous cross-linked polymer may comprise a polymerized polyunsaturated monomer selected from polyacrylates, polymethacrylates, polyitaconates, and mixtures thereof. The carrier can be non-aqueous, and can comprise a film forming material. Methods are also provided for whitening a tooth surface with the tooth whitening compositions.

Abstract translation: 在各种实施方案中，本发明提供了包含过氧化物复合物和口服可接受的载体的牙齿增白组合物。 过氧化物复合物包括过氧化物化合物和多孔交联聚合物，优选为微孔颗粒形式。 过氧化物可以吸附到多孔交联聚合物上。 多孔交联聚合物可以包含选自聚丙烯酸酯，聚甲基丙烯酸酯，多衣康酸酯及其混合物的聚合的多不饱和单体。 载体可以是非水的，并且可以包含成膜材料。 还提供了用于使牙齿美白组合物使牙齿美白的方法。

公开(公告)号：US06542551B1

公开(公告)日：2003-04-01

申请号：US09315475

申请日：1999-05-20

Applicant: Yuri Okunev ,  Vitaly Drucker ,  Qin Wang ,  Yuri Goldstein

Inventor： Yuri Okunev ,  Vitaly Drucker ,  Qin Wang ,  Yuri Goldstein

IPC: H04B1404

CPC classification number: H04L25/4927 ,  H04B14/048 ,  H04J3/125

Abstract: The receiver of a PCM modem utilizes the V.90 TRN1d training signal for detecting whether any of the six slots of the received signal may be subject to alternating robbed bit signaling (ARBS), and what the alternating robbed bit signaling pattern may be. This is accomplished by accumulating the received level over a plurality of frames for each slot and by comparing the received levels for each slot to an average level for that slot. If the difference between the received levels and the average levels exceeds a threshold, the slot is determined to be subject to ARBS. Where a slot is subject to ARBS, DIL sequence signals for frames of the alternating robbed bit signaling slot having LSB=0 and LSB=1 are accumulated separately (if available) in order to generate two translation tables (TRT0, TRT1) for that slot. Where the DIL sequence is found only in the frames having the alternating robbed bit signaling slot having LSB=0 or having LSB=1, only one translation table can be generated. Different algorithms are provided for designing a constellation for the alternating robbed bit signaling slot depending on (a) whether two translation tables were generated for the slot, (b) whether the frame-to-TRT correspondence is known, and (c) where only one translation table is generated, whether the translation table generated was TRT0 or TRT1.

Abstract translation: PCM调制解调器的接收机利用V.90 TRN1d训练信号来检测接收信号的六个时隙中的任一个是否可能经历交替的抢占位信令（ARBS），以及交替的抢占位信令模式可能是什么。 这是通过在每个时隙的多个帧上累积接收的电平并且通过将每个时隙的接收电平与该时隙的平均电平进行比较来实现的。 如果接收电平和平均电平之间的差异超过阈值，则确定该时隙被接受ARBS。 在时隙经受ARBS的情况下，具有LSB = 0和LSB = 1的交替抢占位信令时隙的帧的DIL序列信号被分别累积（如果可用），以便为该时隙产生两个转换表（TRT0，TRT1） 。 在仅具有LSB = 0或具有LSB = 1的交替抢夺位信令时隙的帧中找到DIL序列的情况下，只能生成一个转换表。 提供了不同的算法用于设计用于交替抢夺位信令时隙的星座，这取决于（a）是否为时隙生成了两个转换表，（b）帧到TRT对应是否已知，以及（c） 生成一个转换表，生成的转换表是否为TRT0或TRT1。

公开(公告)号：US06272171B1

公开(公告)日：2001-08-07

申请号：US09238302

申请日：1999-01-28

Applicant: Yuri Okunev ,  Vitaly Drucker ,  Qin Wang ,  Yuri Goldstein

Inventor： Yuri Okunev ,  Vitaly Drucker ,  Qin Wang ,  Yuri Goldstein

IPC: H04B138

CPC classification number: H04L25/4927 ,  H04J3/125

Abstract: Methods are provided for determining whether any slots of a modem frame are subject to robbed bit signaling (RBS), and whether the robbed bit signaling is &bgr;-codec robbed bit signaling. From an obtained DIL sequence, an ordered table of level values for each slot is generated. In determining whether any slots are RBS slots, distances between adjacent levels of the table for each slot are obtained and are compared to a “zero distance” threshold value in order to determine the number of distances which exceed the “zero distance” value. For each slot, the number of zero distances are compared to a threshold value, and if the number of zero distances exceeds the threshold value, the slot is declared to be a RBS slot. Zero distance thresholds for each slot are generated by finding a function of a maximum distance for that slot among the adjacent levels. In determining whether any RBS slots are &bgr;-codec slots, distances are found between corresponding levels of the ordered tables. If substantially more than half of the distances from one slot to the others are found to be greater than a zero distance threshold value, the slot is determined to be a &bgr;-codec slot.

Abstract translation: 提供了用于确定调制解调器帧的任何时隙是否遭受抢占比特信令（RBS）以及抢占比特信令是否为β-codec抢夺比特信令的方法。 从获得的DIL序列中，生成每个时隙的级别值的有序表。 在确定任何时隙是否是RBS时隙时，获得每个时隙的表的相邻电平之间的距离，并将其与“零距离”阈值进行比较，以便确定超过“零距离”值的距离数。 对于每个时隙，将零距离的数量与阈值进行比较，并且如果零距离的数量超过阈值，则该时隙被声明为RBS时隙。 通过找到相邻级别中该时隙的最大距离的函数来生成每个时隙的零距离阈值。 在确定任何RBS时隙是否为β编解码器插槽时，在有序表的相应级别之间找到距离。 如果发现从一个时隙到另一个时隙的距离的大致一半大于零距离阈值，那么该时隙被确定为β-codec时隙。

公开(公告)号：US11109889B2

公开(公告)日：2021-09-07

申请号：US16091461

申请日：2016-04-05

Applicant: Qin Wang

Inventor： Qin Wang

IPC: A61B17/34 ,  A61B90/11

Abstract: A double-sided needle groove, a frame body and a puncture frame, wherein the double-sided needle groove has an axisymmetric outer contour, and is provided at one side with at least one needle slot a (1) and at the other side with at least one needle slot b (2); and the needle slot b (2) is fan-shaped. The double-sided needle groove is provided with one or more needle slots a (1) having a fixed needle insertion angle and a needle slot b (2) having an adjustable needle insertion angle, and the needle slot a (1) and the needle slot b (2) respectively correspond to the diameters of puncture needles and may be designed to meet multiple width specifications. During the performance of a B-ultrasound puncture operation, based on operation requirements of a surgeon for a fixed or adjustable angle, there is only a need to switch front and back sides of the double-sided needle groove, thus avoiding the need for an additional puncture frame, and switch the needle slots according to the diameters of the puncture needles. As can be seen, the double-sided needle groove can be applied to various types of B-ultrasound puncture operations and can effectively reduce the number of accessories in the puncture operations, thereby providing fast installation, saving resources and reducing costs.

公开(公告)号：US11033297B2

公开(公告)日：2021-06-15

申请号：US15773930

申请日：2015-12-25

Applicant: Qin Wang

Inventor： Qin Wang

IPC: A61B17/34 ,  A61B8/08 ,  A61B90/00 ,  A61B17/00

Abstract: A needle guide holder, which is used for a fixing medical puncture needle and a ultrasonic probe, comprises a holder body (1a, 1b) and a fixing device (2a, 2b) used in cooperation with the holder body (1a, 1b). The fixing device (2a, 2b) is mounted onto the holder body (1a, 1b) and provided with a weakening portion (23a, 23b). The needle guide holder is designed to be disposable, thereby avoiding the possibility of cross-infection caused by using the same needle guide holder on different patients. The needle guide holder can be used on one and same patient to perform a number of treatments just through the replacement of a sliding frame and without replacing the fixing device and a fixing frame. In a treatment process, the puncture needle is left in the body for a subsequent treatment, while the needle guide holder and the ultrasonic probe can be removed from the human body.