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1.发明申请公开(公告)号：US20060147394A1
公开(公告)日：2006-07-06
申请号：US11285871
申请日：2005-11-23
申请人： Ramachandra Shastry , Yelloji Mirajkar , Nagaraj Dixit , Ryan Cameron , Qin Wang , Lynette Zaidel , Suman Chopra , Michael Prencipe
发明人： Ramachandra Shastry , Yelloji Mirajkar , Nagaraj Dixit , Ryan Cameron , Qin Wang , Lynette Zaidel , Suman Chopra , Michael Prencipe
IPC分类号： A61K8/00
CPC分类号： A61K8/22 , A61K8/8152 , A61Q11/00
摘要： In various embodiments, the present invention provides a tooth whitening composition comprising a peroxide composite and an orally acceptable carrier. The peroxide composite comprises a peroxide compound and a porous cross-linked polymer, preferably in the form of a microporous particulate. The peroxide compound can be sorbed onto the porous crosslinked polymer. The porous cross-linked polymer may comprise a polymerized polyunsaturated monomer selected from polyacrylates, polymethacrylates, polyitaconates, and mixtures thereof. The carrier can be non-aqueous, and can comprise a film forming material. Methods are also provided for whitening a tooth surface with the tooth whitening compositions.
摘要翻译： 在各种实施方案中，本发明提供了包含过氧化物复合物和口服可接受的载体的牙齿增白组合物。 过氧化物复合物包括过氧化物化合物和多孔交联聚合物，优选为微孔颗粒形式。 过氧化物可以吸附到多孔交联聚合物上。 多孔交联聚合物可以包含选自聚丙烯酸酯，聚甲基丙烯酸酯，多衣康酸酯及其混合物的聚合的多不饱和单体。 载体可以是非水的，并且可以包含成膜材料。 还提供了用于使牙齿美白组合物使牙齿美白的方法。
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公开(公告)号：US20050210615A1
公开(公告)日：2005-09-29
申请号：US10811723
申请日：2004-03-29
IPC分类号： A61C15/00 , A61C19/06 , A61F13/00 , A61K8/02 , A61K8/22 , A61Q11/00 , A61Q11/02 , A61K7/16 , A47L23/04
CPC分类号： A61K8/0208 , A61C19/063 , A61K8/22 , A61K2800/88 , A61Q11/00
摘要： A method for improving effectiveness of an oral care agent comprises preconditioning an oral surface by wiping the surface with an absorbent fabric having impregnated therein or coated thereon an orally acceptable preconditioning agent such as an activating agent for the oral care agent, wherein the wiping transfers an activating effective amount of the preconditioning agent from the fabric to the oral surface, and thereafter applying a composition comprising the oral care agent to the oral surface.
摘要翻译： 一种用于提高口腔护理剂的有效性的方法包括通过用浸渍在其中的吸收性织物擦拭表面来预处理口腔表面，或者在其上涂覆口腔可接受的预处理剂，例如用于口腔护理剂的活化剂，其中擦拭将 将有效量的预处理剂从织物活化至口腔表面，然后将包含口腔护理剂的组合物施用于口腔表面。
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3.发明申请公开(公告)号：US20050069502A1
公开(公告)日：2005-03-31
申请号：US10917263
申请日：2004-08-12
申请人： Suman Chopra , Lynette Zaidel , Guisheng Pan , Suryakant Patel , Ryan Cameron , Michael Prencipe
发明人： Suman Chopra , Lynette Zaidel , Guisheng Pan , Suryakant Patel , Ryan Cameron , Michael Prencipe
IPC分类号： A61C19/06 , A61K8/20 , A61K8/22 , A61K8/38 , A61K8/81 , A61K8/89 , A61K8/891 , A61Q11/00 , A61Q11/02 , A61K7/20
CPC分类号： A61Q11/00 , A61C19/066 , A61K8/22 , A61K8/8111 , A61K8/8176 , A61K8/891
摘要： A tooth whitening system comprising a tooth whitening composition comprising a whitening agent and a hydrophobic polymer carrier. The tooth whitening composition is preferably substantially non-water soluble. The tooth whitening composition is applied to the surface of a tooth to be whitened in a mammal to effect whitening on the tooth surface. Methods of whitening a surface of a tooth are also provided.
摘要翻译： 一种牙齿美白系统，其包括含有增白剂和疏水聚合物载体的牙齿增白组合物。 牙齿美白组合物优选基本上是非水溶性的。 将牙齿美白组合物施用于哺乳动物中待白化牙齿的表面以在牙齿表面上发白。 还提供了使牙齿表面变白的方法。
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公开(公告)号：US09682027B2
公开(公告)日：2017-06-20
申请号：US12058424
申请日：2008-03-28
申请人： Michael Prencipe , Diane Cummins , Richard Scott Robinson , Sarita V. Mello , Richard J. Sullivan , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Ralph Peter Santarpia, III , Qin Wang , Gary Edward Tambs , Rajnish Kohli , Virginia Monsul Barnes , Sergio Leite , Eric A. Simon
发明人： Michael Prencipe , Diane Cummins , Richard Scott Robinson , Sarita V. Mello , Richard J. Sullivan , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Ralph Peter Santarpia, III , Qin Wang , Gary Edward Tambs , Rajnish Kohli , Virginia Monsul Barnes , Sergio Leite , Eric A. Simon
CPC分类号： A61K8/44 , A61K8/25 , A61K31/198 , A61Q11/00
摘要： This invention relates to oral care compositions comprising a basic amino acid or salt thereof, and a small particle fraction: and to methods of using and of making these compositions.
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公开(公告)号：US20090202454A1
公开(公告)日：2009-08-13
申请号：US12058209
申请日：2008-03-28
申请人： Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
发明人： Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
摘要： This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an antibacterial agent, and to methods of using and of making such compositions.
摘要翻译： 本发明涉及包含游离或盐形式的有效量的碱性氨基酸与抗菌剂的口腔护理组合物，以及使用和制备这些组合物的方法。
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公开(公告)号：US20050038181A1
公开(公告)日：2005-02-17
申请号：US10642458
申请日：2003-08-15
申请人： Suman Chopra , Lynette Zaidel , Guisheng Pan , Suryakant Patel , Ryan Cameron , Michael Prencipe
发明人： Suman Chopra , Lynette Zaidel , Guisheng Pan , Suryakant Patel , Ryan Cameron , Michael Prencipe
CPC分类号： A61K8/22 , A61C19/066 , A61K8/8176 , A61K8/891 , A61Q11/00
摘要： A stable, nonaqueous liquid tooth whitening composition comprised of an anhydrous peroxide compound dispersed in an orally acceptable hydrophobic organic material such as a silicone based pressure sensitive polymer which composition when applied topically to tooth surfaces forms an adherent layer containing the peroxide compound which peroxide compound is thereafter is released from the layer to effect tooth whitening.
摘要翻译： 一种稳定的非水液体牙齿增白组合物，其由分散在口腔可接受的疏水性有机材料如硅氧烷基压敏聚合物中的无水过氧化物组合物组成，该组合物当局部施用于牙齿表面时形成含有过氧化物化合物的粘附层， 此后从该层释放以实现牙齿美白。
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公开(公告)号：US20090202456A1
公开(公告)日：2009-08-13
申请号：US12058387
申请日：2008-03-28
申请人： Michael Prencipe , Guofeng Xu , Ravi Subramanyam , Donghui Wu , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Sarita V. Mello , Lynette Zaidel , Suman Chopra , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Andre M. Morgan , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
发明人： Michael Prencipe , Guofeng Xu , Ravi Subramanyam , Donghui Wu , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Sarita V. Mello , Lynette Zaidel , Suman Chopra , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Andre M. Morgan , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
IPC分类号： A61K8/44 , A61K31/195 , A61Q11/00
CPC分类号： A61K8/44 , A61K8/463 , A61K8/55 , A61K8/8164 , A61K31/198 , A61Q11/00
摘要： The invention relates to novel arginine salts, compositions comprising them, and their uses.
摘要翻译： 本发明涉及新颖的精氨酸盐，包含它们的组合物及其用途。
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公开(公告)号：US20090202455A1
公开(公告)日：2009-08-13
申请号：US12058360
申请日：2008-03-28
申请人： Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
发明人： Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
摘要： This invention relates to oral care compositions comprising an effective amount of a salt of a basic amino acid the salt having a pH in an unbuffered solution of less than about 7.5; an effective amount of a soluble fluoride salt; and a particulate material which has a pH in an unbuffered solution of less than about 7.5; and to methods of using and of making such compositions.
摘要翻译： 本发明涉及口腔护理组合物，其包含有效量的碱性氨基酸盐，该盐在无缓冲溶液中的pH值小于约7.5; 有效量的可溶性氟化物盐; 以及具有小于约7.5的无缓冲溶液中的pH的颗粒材料; 以及使用和制备这种组合物的方法。
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公开(公告)号：US20080274065A1
公开(公告)日：2008-11-06
申请号：US12028782
申请日：2008-02-08
申请人： Richard Scott Robinson , Richard J. Sullivan , Michael Prencipe , Rajnish Kohli , Isabelle Van Rycke , Richard Lovell , Sergio Leite , Eric A. Simon , Ralph Peter Santarpia , Diane Cummins , Sarita V. Mello , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
发明人： Richard Scott Robinson , Richard J. Sullivan , Michael Prencipe , Rajnish Kohli , Isabelle Van Rycke , Richard Lovell , Sergio Leite , Eric A. Simon , Ralph Peter Santarpia , Diane Cummins , Sarita V. Mello , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
CPC分类号： A61K8/25 , A61K8/44 , A61K2800/28 , A61K2800/412 , A61K2800/88 , A61Q11/00
摘要： The invention includes methods of cleaning an oral surface, maintaining oral health and/or increasing oral health. Such methods encompass contacting an oral surface with a primary oral care composition at least once daily, contacting the oral surface with a periodic oral care maintenance composition at least once monthly, wherein the periodic oral care maintenance composition comprises a basic amino acid, in free or salt form and optionally contacting the oral surface with a periodic oral care cleaning composition at least once monthly. The periodic oral care cleaning compositions suitable for use in the method comprise an abrasive system.
摘要翻译： 本发明包括清洁口腔表面，维持口腔健康和/或增加口腔健康的方法。 这样的方法包括每天至少一次使口腔表面与主要口腔护理组合物接触，使口腔表面与定期的口腔护理维持组合物每月至少一次接触，其中定期口腔护理维持组合物包含游离或 任选地使口腔表面与定期的口腔护理清洁组合物每月至少一次接触。 适用于该方法的定期口腔护理清洁组合物包括研磨系统。
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公开(公告)号：US09682026B2
公开(公告)日：2017-06-20
申请号：US12058360
申请日：2008-03-28
申请人： Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
发明人： Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
IPC分类号： A61K8/00 , A61Q11/00 , A61K8/25 , A61K8/21 , A61K8/19 , A61K8/40 , A61K8/44 , A61K8/24 , A61K31/198
摘要： This invention relates to oral care compositions comprising an effective amount of a salt of a basic amino acid the salt having a pH in an unbuffered solution of less than about 7.5; an effective amount of a soluble fluoride salt; and a particulate material which has a pH in an unbuffered solution of less than about 7.5; and to methods of using and of making such compositions.
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